Extract from the Register of European Patents

EP Citations: EP3218406

Cited inInternational search
Type:Non-patent literature
Publication information:[XI]   J. STAGG ET AL: "Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 107, no. 4, 4 January 2010 (2010-01-04), US, pages 1547 - 1552, XP055245510, ISSN: 0027-8424, DOI: 10.1073/pnas.0908801107
DOI: http://dx.doi.org/10.1073/pnas.0908801107
Type:Non-patent literature
Publication information:[X]   B. ALLARD ET AL: "Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs", CLINICAL CANCER RESEARCH, vol. 19, no. 20, 15 October 2013 (2013-10-15), pages 5626 - 5635, XP055216360, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-13-0545
DOI: http://dx.doi.org/10.1158/1078-0432.CCR-13-0545
Cited inOpposition
Type:Patent literature
Publication No.:WO2016075099  
Type:Patent literature
Publication No.:WO2016055609  
Type:Patent literature
Publication No.:WO2014153424  
Type:Patent literature
Publication No.:WO2016081748  
Type:Patent literature
Publication No.:US2009203538  
Type:Patent literature
Publication No.:WO2016055609  
Type:Patent literature
Publication No.:WO2016081748  
Type:Patent literature
Publication No.:US2009203538  
Type:Non-patent literature
Publication information:  HUSLER ET AL.: "Anti- CD 39 and anti- CD 73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion", AM J TRANSL RES, vol. 6, no. 2, 2014, pages 129 - 139, XP055240896
Type:Non-patent literature
Publication information:  ANONYMOUS: "Product datasheet Anti-CD73 antibody [7G2] ab54217 ", ABCAM, 1 January 2009 (2009-01-01), pages 1 - 3, XP055879813, [retrieved on 20220117] * D2a E-mail from Abcam regarding cat. no. ab54217, antibody clone 7G2 *
Type:Non-patent literature
Publication information:  THOMSON ET AL.: "Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5'- nucleotidase CD 73", TISSUE ANTIGENS, vol. 35, no. 1, 1990, pages 9 - 19, XP008131950, DOI: 10.1111/j.1399-0039.1990.tb01750.x
DOI: http://dx.doi.org/10.1111/j.1399-0039.1990.tb01750.x
Type:Non-patent literature
Publication information:  GOUDENEGE ET AL.: "Myoblasts derived from normal hESCs and dystrophic hiPSCs efficiently fuse with existing muscle fibers following transplantation", MOL THER, vol. 20, no. 11, 2012, pages 2153 - 2167, XP055457899, DOI: 10.1038/mt.2012.188
DOI: http://dx.doi.org/10.1038/mt.2012.188
Type:Non-patent literature
Publication information:  ANONYMOUS: "CD73 Monoclonal Antibody (AD2), APC, eBioscience", INVITROGEN, 1 January 2017 (2017-01-01), pages 1 - 2, XP055879871, Retrieved from the Internet [retrieved on 20220117]
Type:Non-patent literature
Publication information:  ANONYMOUS: "Product Datasheet 5'-Nucleotidase/CD73 Antibody (AD2) NBP2-48480 Earn rewards for product reviews and publications", NOVUSBIO, 1 January 2012 (2012-01-01), pages 1 - 5, XP055879876, Retrieved from the Internet [retrieved on 20220117] * D7a E-mail from Novus Biologicals regarding cat. nos. NBP2-48480 (antibody clone AD2 and NBP1 -60135 (antibody clone 4G4) *
Type:Non-patent literature
Publication information:  AIRAS ET AL.: "Differential regulation and function of CD 73, a glycosyl-phosphatidylinositol- linked 70-kD adhesion molecule, on lymphocytes and endothelial cells", J CELL BIOL, vol. 136, no. 2, 1997, pages 421 - 431, XP055242069, DOI: 10.1083/jcb.136.2.421
DOI: http://dx.doi.org/10.1083/jcb.136.2.421
Type:Non-patent literature
Publication information:  CINTI ALESSANDRO, ET AL: "Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF--Induced Injury In Vitro", PLOS ONE, 1 October 2015 (2015-10-01), pages 1 - 23, XP055879866, Retrieved from the Internet [retrieved on 20220117], DOI: 10.1371/journal.pone.0141933
DOI: http://dx.doi.org/10.1371/journal.pone.0141933
Type:Non-patent literature
Publication information:  ANONYMOUS: "Product Datasheet 5'-Nucleotidase/CD73 Antibody (4G4) NBP1-60135-0.05mg Earn rewards for product reviews and publications", NOVIUSBIO, 6 May 2020 (2020-05-06), pages 1 - 3, XP055879883, Retrieved from the Internet [retrieved on 20220117] * D12a Excerpt web page of Novus Biologicals of cat. no. NBP1-60135, antibody clone 4G4 https://www.novusbio.com/products/5-nucleotidase-cd73-antibody-4q4 nbp1-60135 *
Type:Non-patent literature
Publication information:  GROZIO ALESSIA, ET AL: "CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 288, no. 36, 23 July 2013 (2013-07-23), US , pages 25938 - 25949, XP055879886, ISSN: 0021-9258, DOI: 10.1074/jbc.M113.470435
DOI: http://dx.doi.org/10.1074/jbc.M113.470435
Type:Non-patent literature
Publication information:  FAUSTHER MICHEL, ET AL: "NT5E Mutations That Cause Human Disease Are Associated with Intracellular Mistrafficking of NT5E Protein", PLOS ONE, 1 June 2014 (2014-06-01), pages 1 - 11, XP055879890, Retrieved from the Internet [retrieved on 20220117], DOI: 10.1371/journal.pone.0098568
DOI: http://dx.doi.org/10.1371/journal.pone.0098568
Type:Non-patent literature
Publication information:  ANONYMOUS: "Anti-CD73 Antibody (2B6): sc-130006", SANTA CRUZ BIOTECHNOLOGY, 1 January 2016 (2016-01-01), pages 1 - 1, XP055879895, Retrieved from the Internet [retrieved on 20220117]
Type:Non-patent literature
Publication information:  DELCOURT NICOLAS, ET AL: "Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 290, no. 6, 1 February 2015 (2015-02-01), US , pages 3405 - 3417, XP055879897, ISSN: 0021-9258, DOI: 10.1074/jbc.M114.618611 * D16a Publication date of D16 *
DOI: http://dx.doi.org/10.1074/jbc.M114.618611
Type:Non-patent literature
Publication information:  GARCIA-ESPARCIA PAULA, ET AL: "Purine metabolism gene deregulation in Parkinson's disease : Purine in PD", NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY., BLACKWELL SCIENTIFIC PUBLICATIONS, LONDON, GB, vol. 41, no. 7, 1 December 2015 (2015-12-01), GB , pages 926 - 940, XP055879903, ISSN: 0305-1846, DOI: 10.1111/nan.12221 * D17a Publication date of D17 *
DOI: http://dx.doi.org/10.1111/nan.12221
Type:Non-patent literature
Publication information:  ANONYMOUS: "NT5E monoclonal antibody (M01), clone 4C4-2B5", ABNOVA, 1 January 2015 (2015-01-01), pages 1 - 1, XP055879910, Retrieved from the Internet [retrieved on 20220117], DOI: 10.1111/nan.12221 * D18a E-mail from Abnova regarding cat. no. H00004907-M01, antibody clone 4C4-2B5 *
DOI: http://dx.doi.org/10.1111/nan.12221
Type:Non-patent literature
Publication information:  NTOKOU AGLAIA, ET AL: "CALL FOR PAPERS Bioengineering the Lung Characterization of the platelet-derived growth factor receptor-alpha-positive cell lineage during murine late lung development", J PHYSIOL LUNG CELL MOL PHYSIOL, 28 August 2015 (2015-08-28), pages 942 - 958, XP055879917, Retrieved from the Internet [retrieved on 20220117]
Type:Non-patent literature
Publication information:  ANONYMOUS: "NT5E/CD73 (D7F9A) Rabbit mAb #13160", CELL SIGNALING, 1 January 2015 (2015-01-01), pages 1 - 2, XP055879926 * D20a E-mail from Cell Signaling regarding cat. no. 13160, antibody clone D7F9A *
Type:Non-patent literature
Publication information:  THOMPSON LF, ET AL: "Antibodies to 5'-nucleotidase (CD73), a glycosyl-phosphatidylinositol- anchored protein, cause human peripheral blood T cells to proliferate", THE JOURNAL OF IMMUNOLOGY (1950), AM ASSOC IMMNOL, UNITED STATES, 15 September 1989 (1989-09-15), United States, pages 1815 - 1821, XP055879929, Retrieved from the Internet [retrieved on 20220117]
Type:Non-patent literature
Publication information:  TERP ET AL.: "Anti-Human CD 73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD 73 expressed on the surface of cancer cells", J IMMUNOL, vol. 191, 2013, pages 4165 - 4173, XP055245512, DOI: 10.4049/jimmunol.1301274
DOI: http://dx.doi.org/10.4049/jimmunol.1301274
Type:Non-patent literature
Publication information:  SUPERNAT ANNA, ET AL: "CD73 expression as a potential marker of good prognosis in breast carcinoma", APPL IMMUNOHISTOCHEM MOL MORPHOL, vol. 20, 1 January 2012 (2012-01-01), pages 103 - 107, XP055879938
Type:Non-patent literature
Publication information:  STAGG ET AL.: "Anti- CD 73 antibody therapy inhibits breast tumor growth and metastasis", PNAS, vol. 107, no. 4, 2010, pages 1547 - 1552, XP055245510, DOI: 10.1073/pnas.0908801107
DOI: http://dx.doi.org/10.1073/pnas.0908801107
Type:Non-patent literature
Publication information:  ALLARD ET AL.: "Targeting CD 73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs", CLIN CANCER RES, vol. 19, no. 20, 2013, pages 5626 - 5635, XP055216360, DOI: 10.1158/1078-0432.CCR-13-0545
DOI: http://dx.doi.org/10.1158/1078-0432.CCR-13-0545
Type:Non-patent literature
Publication information:  HEUTS DOMINIC P. H. M., ET AL: "Crystal Structure of a Soluble Form of Human CD73 with Ecto-5-Nucleotidase Activity", CHEMBIOCHEM, vol. 13, no. 16, 5 November 2012 (2012-11-05), pages 2384 - 2391, XP055879943, ISSN: 1439-4227, DOI: 10.1002/cbic.201200426
DOI: http://dx.doi.org/10.1002/cbic.201200426
Type:Non-patent literature
Publication information:  KNAPP KAREN, ET AL: "Crystal Structure of the Human Ecto-5-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling", STRUCTURE, ELSEVIER, AMSTERDAM, NL, vol. 20, no. 12, 1 December 2012 (2012-12-01), AMSTERDAM, NL , pages 2161 - 2173, XP055879947, ISSN: 0969-2126, DOI: 10.1016/j.str.2012.10.001
DOI: http://dx.doi.org/10.1016/j.str.2012.10.001
Type:Non-patent literature
Publication information:  ALLARD ET AL.: "Targeting CD 73 and downstream adenosine receptor signaling in triple- neaative breast cancer", EXP OPIN THER TARGETS, vol. 18, no. 8, 2014, pages 863 - 881, XP055267045, DOI: 10.1517/14728222.2014.915315
DOI: http://dx.doi.org/10.1517/14728222.2014.915315
Type:Non-patent literature
Publication information:  GEOGHEGAN ET AL.: "Inhibition of CD 73 AMP hydrolysis by a therapeutic antibody with a dual, non- competitive mechanism of action", MABS, vol. 8, no. 3, 2016, pages 454 - 467, XP055533459, DOI: 10.1080/19420862.2016.1143182 * D33a Supplemental figures of D33 *
DOI: http://dx.doi.org/10.1080/19420862.2016.1143182
Type:Non-patent literature
Publication information:  ANTONIOLI LUCA, ET AL: "Immunity, inflammation and cancer: a leading role for adenosine", NATURE REVIEWS CANCER, NATURE PUB. GROUP, LONDON, vol. 13, no. 12, 1 December 2013 (2013-12-01), London , pages 842 - 857, XP055879955, ISSN: 1474-175X, DOI: 10.1038/nrc3613
DOI: http://dx.doi.org/10.1038/nrc3613
Type:Non-patent literature
Publication information:  YOUNG ET AL.: "Taraetina cancer-derived adenosine: new therapeutic approaches", CANCER DISCOV, vol. 4, no. 8, 2014, pages 879 - 888, XP055242089, DOI: 10.1158/2159-8290.CD-14-0341
DOI: http://dx.doi.org/10.1158/2159-8290.CD-14-0341
Type:Non-patent literature
Publication information:  ANTONIOLI ET AL.: "Anti - CD 73 in cancer immunotherapy: awakening new opportunities", TRENDS CANCER, 2016, pages 95 - 109, XP055529454, DOI: 10.1016/j.trecan.2016.01.003
DOI: http://dx.doi.org/10.1016/j.trecan.2016.01.003
Type:Non-patent literature
Publication information:  C OLGAN ET AL.: "Physiological roles for ecto-5'-nucleotidase CD 73", PURINERGIC SIGNALLING, vol. 2, no. 2, 2006, pages 351 - 360, XP019410884, DOI: 10.1007/s11302-005-5302-5
DOI: http://dx.doi.org/10.1007/s11302-005-5302-5
Type:Non-patent literature
Publication information:  ZHANG: "CD 73: a novel target for cancer immunotherapy", CANCER RES, vol. 70, no. 16, 2010, pages 6407 - 6411, XP055252656, DOI: 10.1158/0008-5472.CAN-10-1544
DOI: http://dx.doi.org/10.1158/0008-5472.CAN-10-1544
Type:Non-patent literature
Publication information:  ASCIERTO ET AL.: "Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types", CLIN CANCER RES, 2013, pages 1009 - 1020, XP055124339, DOI: 10.1158/1078-0432.CCR-12-2982
DOI: http://dx.doi.org/10.1158/1078-0432.CCR-12-2982
Type:Non-patent literature
Publication information:  SULT ERIN: "Checkpoint inhibitor combinations with MEDI9447 in a human mixed leukocyte reaction", AACR 106TH ANNUAL MEETING, 9 April 2015 (2015-04-09), pages 1 - 1, XP055879961
Type:Non-patent literature
Publication information:  STEVEN RUST ET AL: "Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer c", MOLECULAR CANCER, BIOMED CENTRAL, LONDON, GB, vol. 12, no. 1, 13 February 2013 (2013-02-13), GB , pages 11, XP021139556, ISSN: 1476-4598, DOI: 10.1186/1476-4598-12-11
DOI: http://dx.doi.org/10.1186/1476-4598-12-11
Type:Non-patent literature
Publication information:  SACHSENMEIER KRIS F, ET AL: "Development of a Novel Ectonucleotidase Assay Suitable for High-Throughput Screening", JOURNAL OF BIOMOLECULAR SCREENING, 1 January 2012 (2012-01-01), pages 993 - 998, XP055879969, Retrieved from the Internet [retrieved on 20220117]
Type:Non-patent literature
Publication information:  MIKE SCHUTKOWSKI, ULRICH REINEKE (EDS.): "Epitope Mapping Protocols : Second Edition; IN: Methods in Molecular Biology; ISSN 1064-3745; Vol. 524", vol. 524, 1 January 2009, HUMANA PRESS , US , ISBN: 978-1-59745-450-6, article M H VAN REGENMORTEL: "What is a B-cell epitope?", pages: 3 - 20, XP055642505, DOI: 10.1007/978-1-59745-450-6_1
DOI: http://dx.doi.org/10.1007/978-1-59745-450-6_1
Type:Non-patent literature
Publication information:  CYTIVA: "Outstanding sensitivity for confident SPR interaction analysis", 1 January 2022 (2022-01-01), pages 1 - 8, XP093104401
Type:Non-patent literature
Publication information:  HOLLIGER PHILIPP; HUDSON PETER J: "ENGINEERED ANTIBODY FRAGMENTS AND THE RISE OF SINGLE DOMAINS", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP US, NEW YORK, vol. 23, no. 9, 1 September 2005 (2005-09-01), New York, pages 1126 - 1136, XP008076746, ISSN: 1087-0156, DOI: 10.1038/nbt1142
DOI: http://dx.doi.org/10.1038/nbt1142
Type:Non-patent literature
Publication information:  CARTER P J: "POTENT ANTIBODY THERAPEUTICS BY DESIGN", NATURE REVIEWS IMMUNOLOGY, NATURE PUBLISHING GROUP UK, LONDON, vol. 6, 7 April 2006 (2006-04-07), London, pages 343 - 357, XP007901440, ISSN: 1474-1733, DOI: 10.1038/nri1837
DOI: http://dx.doi.org/10.1038/nri1837
Type:Non-patent literature
Publication information:  "Concepts and techniques in genomics and proteomics ", 1 July 2011, WOODHEAD PUBLISHING LIMITED, ISBN: 978-1-907568-10-7, article SARASWATHY NACHIMUTHU, PONNUSAMY RAMALINGAM: "Section 14: Protein sequencing techniques", pages: 193 - 201, XP093127370, DOI: 10.1533/9781908818058.193
DOI: http://dx.doi.org/10.1533/9781908818058.193
Type:Non-patent literature
Publication information:  NUNO BANDEIRA, PHAM VICTORIA, PEVZNER PAVEL, ARNOTT DAVID, LILL JENNIE R: "Automated de novo protein sequencing of monoclonal antibodies", NATURE BIOTECHNOLOGY, GALE GROUP INC., vol. 26, no. 12, 1 December 2008 (2008-12-01), pages 1336 - 1338, XP055023375, ISSN: 10870156, DOI: 10.1038/nbt1208-1336
DOI: http://dx.doi.org/10.1038/nbt1208-1336
Type:Non-patent literature
Publication information:  LOISEL, S. OHRESSER, M. PALLARDY, M. DAYDE, D. BERTHOU, C. CARTRON, G. WATIER, H.: "Relevance, advantages and limitations of animal models used in the development of monoclonal antibodies for cancer treatment", CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 62, no. 1, 7 March 2007 (2007-03-07), AMSTERDAM, NL , pages 34 - 42, XP005912444, ISSN: 1040-8428, DOI: 10.1016/j.critrevonc.2006.11.010
DOI: http://dx.doi.org/10.1016/j.critrevonc.2006.11.010
Type:Non-patent literature
Publication information:  ALLARD ET AL.: "Targeting CD 73 and downstream adenosine receptor signaling in triple- neaative breast cancer", EXP OPIN THER TARGETS, vol. 18, no. 8, 2014, pages 863 - 881, XP055267045, DOI: 10.1517/14728222.2014.915315
DOI: http://dx.doi.org/10.1517/14728222.2014.915315
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