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Extract from the Register of European Patents

EP About this file: EP3143036

EP3143036 - PAR-1 BASED THERAPEUTIC CONJUGATES AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.06.2024
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  30.06.2023
FormerGrant of patent is intended
Status updated on  26.02.2023
FormerExamination is in progress
Status updated on  03.03.2020
FormerRequest for examination was made
Status updated on  17.02.2017
FormerThe international publication has been made
Status updated on  02.12.2016
Most recent event   Tooltip07.06.2024No opposition filed within time limitpublished on 10.07.2024  [2024/28]
Applicant(s)For all designated states
Tel Hashomer Medical Research Infrastructure and Services Ltd.
The Chaim Sheba Medical Center
52621 Ramat Gan / IL
[2017/12]
Inventor(s)01 / CHAPMAN, Joab
24 Remez Street
55212 Kiryat Ono / IL
02 / SHAVIT-STEIN, Efrat
13 Tritch Street
69860 Tel Aviv / IL
 [2017/12]
Representative(s)Gassner, Birgitta, et al
REDL Life Science Patent Attorneys
Donau-City-Straße 11
1220 Wien / AT
[2017/12]
Application number, filing date15793541.211.05.2015
[2017/12]
WO2015IL50488
Priority number, dateUS201461991532P11.05.2014         Original published format: US 201461991532 P
US201562137846P25.03.2015         Original published format: US 201562137846 P
[2017/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2015173802
Date:19.11.2015
Language:EN
[2015/46]
Type: A1 Application with search report 
No.:EP3143036
Date:22.03.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 19.11.2015 takes the place of the publication of the European patent application.
[2017/12]
Type: B1 Patent specification 
No.:EP3143036
Date:02.08.2023
Language:EN
[2023/31]
Search report(s)International search report - published on:IL19.11.2015
(Supplementary) European search report - dispatched on:EP31.01.2018
ClassificationIPC:C07K7/02, C07K5/02, A61K38/04, A61P25/00
[2017/12]
CPC:
A61K45/06 (EP,US); A61K38/1796 (US); A61K31/519 (EP);
A61K38/57 (US); A61K47/54 (EP); A61P25/00 (EP);
C07K14/723 (EP,US); C07K5/0806 (EP,US); C07K5/0819 (EP,US);
C07K5/101 (EP,US); C07K5/1024 (EP,US); A61K38/00 (EP,US) (-)
C-Set:
A61K31/519, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/12]  
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:PAR-1-BASIERTE THERAPEUTISCHE KONJUGATE UND VERWENDUNGEN DAVON[2017/12]
English:PAR-1 BASED THERAPEUTIC CONJUGATES AND USES THEREOF[2017/12]
French:CONJUGUÉS THÉRAPEUTIQUES À BASE DE PAR-1 ET UTILISATIONS CORRESPONDANTES[2017/12]
Entry into regional phase02.12.2016National basic fee paid 
02.12.2016Search fee paid 
02.12.2016Designation fee(s) paid 
02.12.2016Examination fee paid 
Examination procedure02.12.2016Examination requested  [2017/12]
02.12.2016Date on which the examining division has become responsible
30.07.2018Amendment by applicant (claims and/or description)
06.03.2020Despatch of a communication from the examining division (Time limit: M04)
06.07.2020Reply to a communication from the examining division
27.02.2023Communication of intention to grant the patent
23.06.2023Fee for grant paid
23.06.2023Fee for publishing/printing paid
23.06.2023Receipt of the translation of the claim(s)
Opposition(s)03.05.2024No opposition filed within time limit [2024/28]
Fees paidRenewal fee
23.05.2017Renewal fee patent year 03
25.05.2018Renewal fee patent year 04
23.05.2019Renewal fee patent year 05
22.05.2020Renewal fee patent year 06
18.05.2021Renewal fee patent year 07
25.05.2022Renewal fee patent year 08
26.05.2023Renewal fee patent year 09
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCZ02.08.2023
HR02.08.2023
PL02.08.2023
RO02.08.2023
RS02.08.2023
SK02.08.2023
SM02.08.2023
NO02.11.2023
GR03.11.2023
IS02.12.2023
[2024/23]
Former [2024/20]HR02.08.2023
PL02.08.2023
RS02.08.2023
SM02.08.2023
NO02.11.2023
GR03.11.2023
IS02.12.2023
Former [2024/10]HR02.08.2023
PL02.08.2023
RS02.08.2023
NO02.11.2023
GR03.11.2023
IS02.12.2023
Former [2024/09]NO02.11.2023
GR03.11.2023
IS02.12.2023
Former [2024/08]NO02.11.2023
GR03.11.2023
Documents cited:Search[I]US4161522  (HAMBURGER ROBERT N [US]) [I] 1-3,5-7,9 * column 5, line 18 - line 41; examples 1, 8b, 10, 11; claims 1, 2 *;
 [A]EP1806141  (KOWA CO [JP]) [A] 1-15 * claims 1-8 *;
 [A]WO2011039584  (TSOPANOGLOU NIKOS [GR], et al) [A] 1-15 * claims 1-3; sequences 1, 4 *;
 [A]  - SAMUEL CHACKALAMANNIL, "G-Protein Coupled Receptor Antagonists-1: Protease Activated Receptor-1 (PAR-1) Antagonists as Novel Cardiovascular Therapeutic Agents (Hot Topic: Structure and property Approaches in Recent Drug Discovery Guest Editor: Guo Zhu Zheng)", CURRENT TOPICS IN MEDICINAL CHEMISTRY, (20030501), vol. 3, no. 10, doi:10.2174/1568026033452122, ISSN 1568-0266, pages 1115 - 1123, XP055094137 [A] 1-15 * tables 1, 2 *

DOI:   http://dx.doi.org/10.2174/1568026033452122
International search[A]CA2340461  (UNIV MANITOBA [CA]) [A] 1-20 * paragraph 0032, examples 3 and 4, table 1 *;
 [A]WO02071847  (UNIV EMORY [US], et al) [A] 1-20* FIG. 3, example 2 *;
 [A]WO2011039584  (TSOPANOGLOU NIKOS [GR], et al) [A] 1-20 * SEQ ID NO 4 *;
 [A]WO2013070256  (SCRIPPS RESEARCH INST [US], et al) [A] 1-20 * the whole document, especially paragraph 0062 *;
 [A]WO2013173676  (TUFTS MEDICAL CT INC [US]) [A] 1-20 * table on page 12, page 9 lines 9-20, page 18 lines 6-15 *
by applicantUS2004092535
 US2007142272
 US2009176803
 US2009281100
 US7842716
 US8232295
 US2012232097
    - SHAVIT et al., Brain, (20080000), vol. 131, no. 4, pages 1113 - 1122
    - SHAVIT et al., J Neurochem., vol. 119, no. 3, pages 460 - 473
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.