EP3218376 - BROMODOMAIN INHIBITORS AND USES THEREOF [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 30.10.2020 Database last updated on 24.08.2024 | |
Former | The patent has been granted Status updated on 22.11.2019 | ||
Former | Grant of patent is intended Status updated on 26.06.2019 | ||
Former | Examination is in progress Status updated on 12.10.2018 | ||
Former | Request for examination was made Status updated on 18.08.2017 | ||
Former | The international publication has been made Status updated on 07.06.2017 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Genentech, Inc. 1 DNA Way South San Francisco, CA 94080-4990 / US | For all designated states Constellation Pharmaceuticals, Inc. 215 First Street, Suite 200 Cambridge, MA 02142 / US | [2017/38] | Inventor(s) | 01 /
ALBRECHT, Brian K. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 02 /
BELLON, Steven F. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 03 /
BURDICK, Daniel J. 1 DNA Way South San Francisco, California 94080-4990 / US | 04 /
COTE, Alexandre 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 05 /
CRAWFORD, Terry 1 DNA Way South San Francisco, California 94080-4990 / US | 06 /
DAKIN, Les A. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 07 /
HSIAO-WEI TSUI, Vickie 1 DNA Way South San Francisco, California 94080-4990 / US | 08 /
HEWITT, Michael Charles 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 09 /
LEBLANC, Yves 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 10 /
MAGNUSON, Steven R. 1 DNA Way South San Francisco, California 94080-4990 / US | 11 /
NASVESCHUK, Christopher G. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 12 /
ROMERO, F., Anthony 1 DNA Way South San Francisco, California 94080-4990 / US | 13 /
TANG, Yong 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 14 /
TAYLOR, Alexander M. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | 15 /
WANG, Shumei 1 DNA Way South San Francisco, California 94080-4990 / US | [2019/52] |
Former [2017/38] | 01 /
ALBRECHT, Brian K. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | ||
02 /
BELLON, Steven F. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
03 /
BURDICK, Daniel J. 1 DNA Way South San Francisco, California 94080-4990 / US | |||
04 /
COTE, Alexandre 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
05 /
CRAWFORD, Terry 1 DNA Way South San Francisco, California 94080-4990 / US | |||
06 /
DAKIN, Les A. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
07 /
HSIAO-WEI TSUI, Vickie 1 DNA Way South San Francisco, California 94080-4990 / US | |||
08 /
HEWITT, Michael Charles 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
09 /
LEBLANC, Yves 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
10 /
MAGNUSON, Steven R. 1 DNA Way South San Francisco, California 94080-4990 / US | |||
11 /
NASVESCHUK, Christopher G. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
12 /
ROMERO, F. Anthony 1 DNA Way South San Francisco, California 94080-4990 / US | |||
13 /
TANG, Yong 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
14 /
TAYLOR, Alexander M. 215 First Street Suite 200 Cambridge, Massachusetts 02142 / US | |||
15 /
WANG, Shumei 1 DNA Way South San Francisco, California 94080-4990 / US | Representative(s) | Müller-Boré & Partner Patentanwälte PartG mbB Friedenheimer Brücke 21 80639 München / DE | [2017/38] | Application number, filing date | 15801563.6 | 10.11.2015 | [2017/38] | WO2015US59997 | Priority number, date | US201462077711P | 10.11.2014 Original published format: US 201462077711 P | [2017/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016077375 | Date: | 19.05.2016 | Language: | EN | [2016/20] | Type: | A1 Application with search report | No.: | EP3218376 | Date: | 20.09.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 19.05.2016 takes the place of the publication of the European patent application. | [2017/38] | Type: | B1 Patent specification | No.: | EP3218376 | Date: | 25.12.2019 | Language: | EN | [2019/52] | Search report(s) | International search report - published on: | EP | 19.05.2016 | Classification | IPC: | C07D471/04, C07D519/00 | [2017/38] | CPC: |
A61K31/40 (EP,US);
C07D471/04 (EP,CN,US);
A61P1/00 (EP);
A61P1/04 (EP);
A61P1/16 (EP);
A61P1/18 (EP);
A61P11/00 (EP);
A61P11/06 (EP);
A61P13/12 (EP);
A61P17/00 (EP);
A61P17/02 (EP);
A61P17/04 (EP);
A61P17/06 (EP);
A61P19/00 (EP);
A61P19/02 (EP);
A61P19/06 (EP);
A61P19/08 (EP);
A61P21/00 (EP);
A61P25/00 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P35/00 (EP);
A61P35/02 (EP);
A61P37/02 (EP);
A61P37/06 (EP);
A61P43/00 (EP);
A61P5/00 (EP);
A61P5/16 (EP);
A61P7/04 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/38] | Extension states | BA | 01.06.2017 | ME | 01.06.2017 | Validation states | MA | 01.06.2017 | MD | 01.06.2017 | Title | German: | BROMODOMAININHIBITOREN UND DEREN VERWENDUNG | [2019/28] | English: | BROMODOMAIN INHIBITORS AND USES THEREOF | [2017/38] | French: | INHIBITEURS DE BROMODOMAINE ET LEURS UTILISATIONS | [2019/28] |
Former [2017/38] | BROMODOMAINHEMMER UND VERWENDUNGEN DAVON | ||
Former [2017/38] | INHIBITEURS DE BROMODOMAINES ET LEURS UTILISATIONS | Entry into regional phase | 01.06.2017 | National basic fee paid | 01.06.2017 | Designation fee(s) paid | 01.06.2017 | Examination fee paid | Examination procedure | 31.05.2017 | Date on which the examining division has become responsible | 01.06.2017 | Examination requested [2017/38] | 12.01.2018 | Amendment by applicant (claims and/or description) | 16.10.2018 | Despatch of a communication from the examining division (Time limit: M04) | 08.02.2019 | Reply to a communication from the examining division | 27.06.2019 | Communication of intention to grant the patent | 30.10.2019 | Fee for grant paid | 30.10.2019 | Fee for publishing/printing paid | 30.10.2019 | Receipt of the translation of the claim(s) | Opposition(s) | 28.09.2020 | No opposition filed within time limit [2020/49] | Fees paid | Renewal fee | 13.11.2017 | Renewal fee patent year 03 | 14.11.2018 | Renewal fee patent year 04 | 14.11.2019 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 10.11.2015 | AL | 25.12.2019 | AT | 25.12.2019 | CY | 25.12.2019 | CZ | 25.12.2019 | DK | 25.12.2019 | EE | 25.12.2019 | ES | 25.12.2019 | FI | 25.12.2019 | HR | 25.12.2019 | IT | 25.12.2019 | LT | 25.12.2019 | LV | 25.12.2019 | MC | 25.12.2019 | MK | 25.12.2019 | MT | 25.12.2019 | NL | 25.12.2019 | PL | 25.12.2019 | RO | 25.12.2019 | RS | 25.12.2019 | SE | 25.12.2019 | SI | 25.12.2019 | SK | 25.12.2019 | SM | 25.12.2019 | TR | 25.12.2019 | BG | 25.03.2020 | NO | 25.03.2020 | GR | 26.03.2020 | IS | 25.04.2020 | PT | 20.05.2020 | [2022/32] |
Former [2022/27] | HU | 10.11.2015 | |
AL | 25.12.2019 | ||
AT | 25.12.2019 | ||
CY | 25.12.2019 | ||
CZ | 25.12.2019 | ||
DK | 25.12.2019 | ||
EE | 25.12.2019 | ||
ES | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
IT | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
MC | 25.12.2019 | ||
MT | 25.12.2019 | ||
NL | 25.12.2019 | ||
PL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SI | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
TR | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2021/31] | AL | 25.12.2019 | |
AT | 25.12.2019 | ||
CZ | 25.12.2019 | ||
DK | 25.12.2019 | ||
EE | 25.12.2019 | ||
ES | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
IT | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
MC | 25.12.2019 | ||
NL | 25.12.2019 | ||
PL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SI | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2021/10] | AL | 25.12.2019 | |
AT | 25.12.2019 | ||
CZ | 25.12.2019 | ||
DK | 25.12.2019 | ||
EE | 25.12.2019 | ||
ES | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
IT | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
PL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SI | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2020/51] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
DK | 25.12.2019 | ||
EE | 25.12.2019 | ||
ES | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SI | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2020/47] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
DK | 25.12.2019 | ||
EE | 25.12.2019 | ||
ES | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2020/40] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
EE | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
IS | 25.04.2020 | ||
PT | 20.05.2020 | ||
Former [2020/37] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
EE | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
SK | 25.12.2019 | ||
SM | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
PT | 20.05.2020 | ||
Former [2020/36] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
EE | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
PT | 20.05.2020 | ||
Former [2020/35] | AL | 25.12.2019 | |
CZ | 25.12.2019 | ||
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RO | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
Former [2020/32] | AL | 25.12.2019 | |
FI | 25.12.2019 | ||
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
NL | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
Former [2020/25] | FI | 25.12.2019 | |
HR | 25.12.2019 | ||
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
RS | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
Former [2020/23] | FI | 25.12.2019 | |
LT | 25.12.2019 | ||
LV | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
GR | 26.03.2020 | ||
Former [2020/22] | FI | 25.12.2019 | |
LT | 25.12.2019 | ||
SE | 25.12.2019 | ||
BG | 25.03.2020 | ||
NO | 25.03.2020 | ||
Former [2020/21] | NO | 25.03.2020 | Cited in | International search | [I]US2014162971 (WANG LE [US], et al) [I] 1-24,26-52 * paragraphs [1416] , [1425]; claim 1 *; | [A]US2014256710 (LIU DACHUN [US], et al) [A] 1-52 * the whole document *; | [A] - DANIEL GALLENKAMP ET AL, "Bromodomains and Their Pharmacological Inhibitors", CHEMMEDCHEM, (20140304), vol. 9, no. 3, doi:10.1002/cmdc.201300434, ISSN 1860-7179, pages 438 - 464, XP055124420 [A] 1-52 * the whole document * DOI: http://dx.doi.org/10.1002/cmdc.201300434 | [A] - JEAN-MARC GARNIER ET AL, "BET bromodomain inhibitors: a patent review", EXPERT OPINION ON THERAPEUTIC PATENTS, (201402), vol. 24, no. 2, doi:10.1517/13543776.2014.859244, ISSN 1354-3776, pages 185 - 199, XP055121821 [A] 1-52 * the whole document * DOI: http://dx.doi.org/10.1517/13543776.2014.859244 | by applicant | US4943533 | US5212290 | EP0659439 | US5457105 | US5475001 | WO9603397 | WO9630347 | WO9633978 | WO9633980 | WO9640210 | US5616582 | US5654307 | US5679683 | WO9738983 | WO9814451 | US5747498 | US5760041 | US5770599 | US5804396 | WO9843960 | WO9850433 | WO9850038 | US5866572 | WO9906378 | WO9906396 | WO9909016 | US5891996 | WO9924037 | US6002008 | US6084095 | US6140332 | US6235883 | US6265410 | US6344459 | US6344455 | US6391874 | US6399602 | US6455534 | US6521620 | US6596726 | US6602863 | US6713484 | - STRUHL K., GENES DEV., (1989), vol. 12, no. 5, pages 599 - 606 | - JEANMOUGIN F. ET AL., TRENDS BIOCHEM. SCI., (1997), vol. 22, no. 5, pages 151 - 153 | - TAMKUN J.W. ET AL., CELL, (1992), vol. 7, no. 3, pages 561 - 572 | - PRINJHA ET AL., TRENDS PHARM. SCI., (2012), vol. 33, no. 3, pages 146 - 153 | - MULLER ET AL., EXPERT REV., (201109), vol. 13, no. 29, pages 1 - 20 | - "the Periodic Table of the Elements", DAVID R. LIDE, Handbook of Chemistry and Physics, 75th ed., 00001994 | - WILEN ET AL., TETRAHEDRON, (1977), vol. 33, page 2725 | - WILEN, S.H., Tables of Resolving Agents and Optical Resolutions, UNIV. OF NOTRE DAME PRESS, (1972), page 268 | - ANGEW CHEM. INTL. ED. ENGL., (1994), vol. 33, pages 183 - 186 | - STRAGLIOTTO ET AL., EUR. J. CANCER, (1996), vol. 32A, pages 636 - 640 | - JOHNS, J. BIOL. CHEM., (2004), vol. 279, no. 29, pages 30375 - 30384 |