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EP3221700
European procedure
Extract from the Register of European Patents
EP About this file: EP3221700
| EP3221700 - PRKACB FUSIONS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 28.04.2023 Database last updated on 20.07.2024 | |
| Former | The patent has been granted Status updated on 20.05.2022 | ||
| Former | Grant of patent is intended Status updated on 23.01.2022 | ||
| Former | Examination is in progress Status updated on 30.11.2018 | ||
| Former | Request for examination was made Status updated on 25.08.2017 | ||
| Former | The international publication has been made Status updated on 13.05.2017 | Most recent event Tooltip | 31.05.2024 | Lapse of the patent in a contracting state New state(s): MK | published on 03.07.2024 [2024/27] | Applicant(s) | For all designated states Blueprint Medicines Corporation 38 Sidney Street, suite 200 Cambridge, MA 02139 / US | [2017/39] | Inventor(s) | 01 /
STRANSKY, Nicolas 12 Lexington Street 2 Charlestown, MA 02129 / US | [2017/39] | Representative(s) | Finnegan Europe LLP 1 London Bridge London SE1 9BG / GB | [2022/25] |
| Former [2017/39] | Finnegan Europe LLP 16 Old Bailey London EC4M 7EG / GB | Application number, filing date | 15802296.2 | 17.11.2015 | [2017/39] | WO2015US61073 | Priority number, date | US201462081445P | 18.11.2014 Original published format: US 201462081445 P | [2017/39] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016081450 | Date: | 26.05.2016 | Language: | EN | [2016/21] | Type: | A1 Application with search report | No.: | EP3221700 | Date: | 27.09.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 26.05.2016 takes the place of the publication of the European patent application. | [2017/39] | Type: | B1 Patent specification | No.: | EP3221700 | Date: | 22.06.2022 | Language: | EN | [2022/25] | Search report(s) | International search report - published on: | EP | 26.05.2016 | Classification | IPC: | G01N33/574 | [2017/39] | CPC: |
G01N33/574 (EP,US);
C12Q1/6886 (US);
C12Y207/11001 (EP,US);
G01N33/5743 (US);
G01N33/57496 (US);
C12Q2600/158 (US);
G01N2333/912 (US);
G01N2500/00 (EP,US);
G01N2800/52 (EP,US);
G01N33/57415 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/39] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | FUSIONEN VON PRKACB | [2022/06] | English: | PRKACB FUSIONS | [2017/39] | French: | FUSIONS DE PRKACB | [2017/39] |
| Former [2017/39] | PRKACB-FUSIONEN | Entry into regional phase | 08.06.2017 | National basic fee paid | 08.06.2017 | Designation fee(s) paid | 08.06.2017 | Examination fee paid | Examination procedure | 08.06.2017 | Amendment by applicant (claims and/or description) | 08.06.2017 | Examination requested [2017/39] | 08.06.2017 | Date on which the examining division has become responsible | 30.11.2018 | Despatch of a communication from the examining division (Time limit: M06) | 17.05.2019 | Reply to a communication from the examining division | 23.03.2020 | Despatch of a communication from the examining division (Time limit: M06) | 22.09.2020 | Reply to a communication from the examining division | 03.12.2021 | Cancellation of oral proceeding that was planned for 07.12.2021 | 07.12.2021 | Date of oral proceedings (cancelled) | 24.01.2022 | Communication of intention to grant the patent | 17.05.2022 | Fee for grant paid | 17.05.2022 | Fee for publishing/printing paid | 17.05.2022 | Receipt of the translation of the claim(s) | Opposition(s) | 23.03.2023 | No opposition filed within time limit [2023/22] | Fees paid | Renewal fee | 13.11.2017 | Renewal fee patent year 03 | 14.11.2018 | Renewal fee patent year 04 | 14.11.2019 | Renewal fee patent year 05 | 13.11.2020 | Renewal fee patent year 06 | 21.10.2021 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 17.11.2015 | AL | 22.06.2022 | AT | 22.06.2022 | CY | 22.06.2022 | CZ | 22.06.2022 | DK | 22.06.2022 | EE | 22.06.2022 | ES | 22.06.2022 | FI | 22.06.2022 | HR | 22.06.2022 | IT | 22.06.2022 | LT | 22.06.2022 | LV | 22.06.2022 | MC | 22.06.2022 | MK | 22.06.2022 | NL | 22.06.2022 | PL | 22.06.2022 | RO | 22.06.2022 | RS | 22.06.2022 | SE | 22.06.2022 | SI | 22.06.2022 | SK | 22.06.2022 | SM | 22.06.2022 | BG | 22.09.2022 | NO | 22.09.2022 | GR | 23.09.2022 | IS | 22.10.2022 | PT | 24.10.2022 | GB | 17.11.2022 | IE | 17.11.2022 | LU | 17.11.2022 | BE | 30.11.2022 | CH | 30.11.2022 | FR | 30.11.2022 | LI | 30.11.2022 | [2024/27] |
| Former [2024/21] | HU | 17.11.2015 | |
| AL | 22.06.2022 | ||
| AT | 22.06.2022 | ||
| CY | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| IT | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| BE | 30.11.2022 | ||
| CH | 30.11.2022 | ||
| FR | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2024/18] | HU | 17.11.2015 | |
| AL | 22.06.2022 | ||
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| IT | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| BE | 30.11.2022 | ||
| CH | 30.11.2022 | ||
| FR | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2024/11] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| IT | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| BE | 30.11.2022 | ||
| CH | 30.11.2022 | ||
| FR | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/52] | AL | 22.06.2022 | |
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| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| BE | 30.11.2022 | ||
| CH | 30.11.2022 | ||
| FR | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/49] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| BE | 30.11.2022 | ||
| CH | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/48] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| IE | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| CH | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/47] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| GB | 17.11.2022 | ||
| LU | 17.11.2022 | ||
| CH | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/37] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SI | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| LU | 17.11.2022 | ||
| CH | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/35] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| CH | 30.11.2022 | ||
| LI | 30.11.2022 | ||
| Former [2023/30] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| MC | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/21] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| DK | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/17] | AL | 22.06.2022 | |
| AT | 22.06.2022 | ||
| CZ | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/12] | AT | 22.06.2022 | |
| CZ | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| IS | 22.10.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/11] | AT | 22.06.2022 | |
| CZ | 22.06.2022 | ||
| EE | 22.06.2022 | ||
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| PL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/09] | AT | 22.06.2022 | |
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| EE | 22.06.2022 | ||
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| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| RO | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| SK | 22.06.2022 | ||
| SM | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| PT | 24.10.2022 | ||
| Former [2023/08] | AT | 22.06.2022 | |
| ES | 22.06.2022 | ||
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| Former [2023/07] | AT | 22.06.2022 | |
| FI | 22.06.2022 | ||
| HR | 22.06.2022 | ||
| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
| GR | 23.09.2022 | ||
| Former [2023/02] | FI | 22.06.2022 | |
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| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| NL | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
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| Former [2022/50] | FI | 22.06.2022 | |
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| LT | 22.06.2022 | ||
| LV | 22.06.2022 | ||
| RS | 22.06.2022 | ||
| SE | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
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| Former [2022/49] | FI | 22.06.2022 | |
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| LT | 22.06.2022 | ||
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| SE | 22.06.2022 | ||
| BG | 22.09.2022 | ||
| NO | 22.09.2022 | ||
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| Former [2022/47] | FI | 22.06.2022 | |
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| NO | 22.09.2022 | Cited in | International search | [A]WO2004073609 (PROTEOLOGICS INC [US], et al) [A] 1-33,41,42,56-60 * claims 3-4, 11; p. 63, 2nd par.; p. 73 *; | [A]WO2014038884 (MACROGEN INC [KR], et al) [A] 1-33,41,42,56-60* abstract *; | [XP] - HIROMI NAKAMURA ET AL, "Genomic spectra of biliary tract cancer", NATURE GENETICS., NEW YORK, US, (20150810), vol. 47, no. 9, doi:10.1038/ng.3375, ISSN 1061-4036, pages 1003 - 1010, XP055250263 [XP] 1-33,41,42,56-60 * abstract; fig. 3 * DOI: http://dx.doi.org/10.1038/ng.3375 | by applicant | - M. SODA ET AL., "Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer", NATURE, (2007), vol. 444, doi:doi:10.1038/nature05945, pages 561 - 566, XP002464689 DOI: http://dx.doi.org/10.1038/nature05945 | - T. BROWN, "Hybridization Analysis of DNA Blots", CURRENT PROTOCOLS IN MOLECULAR BIOLOGY, (2001), pages 21.2.10.1 - 21.2.10.16 |