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Extract from the Register of European Patents

EP About this file: EP3230454

EP3230454 - INHIBITORS OF MIR-17-92 CLUSTER FOR ANTI-TUMOR ACTIVITY IN MULTIPLE MYELOMA AND OTHER MALIGNANCIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.08.2018
Database last updated on 02.11.2024
FormerRequest for examination was made
Status updated on  15.09.2017
FormerThe international publication has been made
Status updated on  16.06.2017
Most recent event   Tooltip17.08.2018Application deemed to be withdrawnpublished on 19.09.2018  [2018/38]
Applicant(s)For all designated states
Tassone, Pierfrancesco
Piazzetta Osservanza 2
88100 Catanzaro / IT
For all designated states
Tagliaferri, Pierosandro
Via Cimarosa 89
80127 Napoli / IT
For all designated states
Di Martino, Maria Teresa
Via Benedetto Croce 23
88100 Catanzaro / IT
[2017/42]
Inventor(s)01 / see applicant
...
 [2017/42]
Representative(s)Ghirardi, Valeria, et al
Cantaluppi & Partners S.r.l.
Via Strobel, 8
20133 Milano / IT
[2017/42]
Application number, filing date15804539.304.12.2015
[2017/42]
WO2015EP78655
Priority number, dateIT2014RM0071209.12.2014         Original published format: IT RM20140712
[2017/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016091747
Date:16.06.2016
Language:EN
[2016/24]
Type: A1 Application with search report 
No.:EP3230454
Date:18.10.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 16.06.2016 takes the place of the publication of the European patent application.
[2017/42]
Search report(s)International search report - published on:EP16.06.2016
ClassificationIPC:C12N15/113, A61K31/7088
[2017/42]
CPC:
C12N15/113 (EP,US); A61K31/198 (EP,US); A61K31/713 (EP,US);
C12N2310/113 (EP,US); C12N2310/315 (EP,US); C12N2310/3231 (EP,US);
C12N2310/341 (EP,US); C12N2320/31 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/42]
TitleGerman:INHIBITOREN DES MIR-17-92-CLUSTERS ZUR ANTITUMORAKTIVITÄT IN MULTIPLEM MYELOM UND ANDEREN MALIGNOMEN[2017/42]
English:INHIBITORS OF MIR-17-92 CLUSTER FOR ANTI-TUMOR ACTIVITY IN MULTIPLE MYELOMA AND OTHER MALIGNANCIES[2017/42]
French:INHIBITEURS DU GROUPE MIR-17-92 DESTINÉS À UNE ACTIVITÉ DANS LE MYÉLOME MULTIPLE ET AUTRES TUMEURS MALIGNES[2017/42]
Entry into regional phase07.06.2017National basic fee paid 
07.06.2017Designation fee(s) paid 
07.06.2017Examination fee paid 
Examination procedure07.06.2017Examination requested  [2017/42]
07.06.2017Date on which the examining division has become responsible
16.03.2018Application deemed to be withdrawn, date of legal effect  [2018/38]
24.04.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time  [2018/38]
Fees paidRenewal fee
13.11.2017Renewal fee patent year 03
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Cited inInternational search[XYI]WO2008014008  (THE JOHNS HOPKINS UNIVERSITY [US]) [X] 3,6-8 * claim - * * the whole document * [Y] 14,15 [I] 1,2,4,5,10;
 [XI]WO2006119365  (COLD SPRING HARBOR LABORATORY [US]; UNIVERSITY OF NORTH CAROLINA [US]) [X] 3,6,7 * claim - * * the whole document * [I] 1,2,4,5,10;
 [XI]WO2011106104  (SLOAN KETTERING INST CANCER [US]; UNIV GHENT [BE]; UNIV COLUMBIA [US];) [X] 3,6,7 * claim - * * the whole document * [I] 1,2,4,5,10;
 [A]WO2007095387  (DHARMACON, INC. [US]) [A] 1-11 * page 51 - page 52; table 1; sequence 31 * * the whole document *;
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DOI:   http://dx.doi.org/10.1016/j.canlet.2011.05.017
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DOI:   http://dx.doi.org/10.1210/me.2010-0402
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DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-13-0927
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DOI:   http://dx.doi.org/10.1038/leu.2011.305
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    [ ] - "Supplementary Table S1. Primers used for the 3'UTR cloning", (20120501), URL: http://www.nature.com/leu/journal/v26/n5/extref/leu2011305x7.doc, (20150629), XP055198968
    [ ] - "Supplementary Table S2", (20120501), URL: http://www.nature.com/leu/journal/v26/n5/extref/leu2011305x8.doc, (20150629), XP055198969
    [ ] - "Supplemental Table S3", (20120501), URL: http://www.nature.com/leu/journal/v26/n5/extref/leu2011305x9.doc, (20150629), XP055198970
    [ ] - "Supplemental Table S4", (20120501), URL: http://www.nature.com/leu/journal/v26/n5/extref/leu2011305x10.doc, (20150629), XP055198972
    [ ] - "Supplementary Materials and Methods", (20120501), URL: http://www.nature.com/leu/journal/v26/n5/extref/leu2011305x11.doc, (20150629), XP055198974
 [A]  - D. KALUZA ET AL., "Histone Deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells", ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, (20130301), vol. 33, no. 3, doi:10.1161/ATVBAHA.112.300415, ISSN 1079-5642, pages 533 - 543, XP055198930 [A] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1161/ATVBAHA.112.300415
    [ ] - "Supplement Material Supplemental Methods", (20130301), URL: http://atvb.ahajournals.org/content/suppl/2013/01/03/ATVBAHA.112.300415.DC1/ATV201690-ATVB_ATVB-2012-300415_supp1.pdf, (20150629), XP055198926 [ ] * the whole document *
 [A]  - R. BOMBEN ET AL., "The miR-17~ 92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes", LEUKEMIA, (20120701), vol. 26, no. 7, doi:10.1038/leu.2012.44, ISSN 0887-6924, pages 1584 - 1593, XP055198859 [A] 1-11 * the whole document *

DOI:   http://dx.doi.org/10.1038/leu.2012.44
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    [ ] - "Table S1 Biological features of CLL cases", (20120701), URL: http://www.nature.com/leu/journal/v26/n7/extref/leu201244x2.xls, (20150629), XP055198947
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    [ ] - "Table S4 GO categories differentially represented in CpG stimulated versus unstimulated UM CLL samples", (20120701), URL: http://www.nature.com/leu/journal/v26/n7/extref/leu201244x5.xls, (20150629), XP055198950
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DOI:   http://dx.doi.org/10.1038/onc.2010.83
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DOI:   http://dx.doi.org/10.1038/ng1855
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DOI:   http://dx.doi.org/10.1038/cdd.2013.125
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