EP3227300 - ALDOSTERONE SYNTHASE INHIBITORS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 03.07.2020 Database last updated on 02.11.2024 | |
Former | The patent has been granted Status updated on 17.05.2019 | ||
Former | Grant of patent is intended Status updated on 14.05.2019 | ||
Former | Examination is in progress Status updated on 01.05.2019 | ||
Former | Grant of patent is intended Status updated on 23.01.2019 | ||
Former | Examination is in progress Status updated on 30.03.2018 | ||
Former | Request for examination was made Status updated on 08.09.2017 | ||
Former | The international publication has been made Status updated on 19.04.2017 | Most recent event Tooltip | 01.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 03.08.2022 [2022/31] | Applicant(s) | For all designated states Boehringer Ingelheim International GmbH Binger Strasse 173 55216 Ingelheim am Rhein / DE | [2017/41] | Inventor(s) | 01 /
CHEN, Zhidong c/o VP IP Legal Boehringer Ingelheim USA Corp. 900 Ridgebury Rd., P.O. Box 368 Ridgefield, Connecticut 06877-0368 / US | 02 /
COGAN, Derek 290 Commonwealth Ave, 11 Boston, MA 02115 / US | 03 /
GUO, Xin c/o VP IP Legal Boehringer Ingelheim USA Corp. 900 Ridgebury Rd., P.O. Box 368 Ridgefield, Connecticut 06877-0368 / US | 04 /
MARSHALL, Daniel Richard c/o VP IP Legal Boehringer Ingelheim USA Corp. 900 Ridgebury Rd., P.O. Box 368 Ridgefield, Connecticut 06877-0368 / US | 05 /
MEYERS, Kenneth Michael c/o VP IP Legal Boehringer Ingelheim USA Corp. 900 Ridgebury Rd., P.O. Box 368 Ridgefield, Connecticut 06877-0368 / US | 06 /
ZHANG, Yunlong c/o VP IP Legal Boehringer Ingelheim USA Corp. 900 Ridgebury Rd., P.O. Box 368 Ridgefield, Connecticut 06877-0368 / US | [2017/41] | Representative(s) | Simon, Elke Anna Maria, et al Boehringer Ingelheim GmbH Binger Strasse 173 55216 Ingelheim am Rhein / DE | [2017/41] | Application number, filing date | 15813641.6 | 01.12.2015 | [2017/41] | WO2015US63064 | Priority number, date | US201462086218P | 02.12.2014 Original published format: US 201462086218 P | [2017/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016089800 | Date: | 09.06.2016 | Language: | EN | [2016/23] | Type: | A1 Application with search report | No.: | EP3227300 | Date: | 11.10.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.06.2016 takes the place of the publication of the European patent application. | [2017/41] | Type: | B1 Patent specification | No.: | EP3227300 | Date: | 19.06.2019 | Language: | EN | [2019/25] | Search report(s) | International search report - published on: | EP | 09.06.2016 | Classification | IPC: | C07D491/052, C07D519/00, A61K31/436, A61K31/4704, A61K31/4709, A61K31/4725, A61K31/437, A61K31/4375, A61K31/55, A61K31/553, A61P9/00 | [2017/41] | CPC: |
C07D491/052 (EP,US);
A61P13/12 (EP);
A61P3/10 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/41] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | ALDOSTERONE SYNTHASE INHIBITOREN | [2019/06] | English: | ALDOSTERONE SYNTHASE INHIBITORS | [2017/41] | French: | INHIBITEURS D'ALDOSTERONE SYNTHASE | [2019/06] |
Former [2017/41] | ALDOSTERONSYNTHASEHEMMER | ||
Former [2017/41] | INHIBITEURS DE L'ALDOSTÉRONE SYNTHASE | Entry into regional phase | 03.07.2017 | National basic fee paid | 03.07.2017 | Designation fee(s) paid | 03.07.2017 | Examination fee paid | Examination procedure | 19.04.2017 | Date on which the examining division has become responsible | 03.07.2017 | Examination requested [2017/41] | 24.08.2017 | Amendment by applicant (claims and/or description) | 03.04.2018 | Despatch of a communication from the examining division (Time limit: M04) | 06.07.2018 | Reply to a communication from the examining division | 24.01.2019 | Communication of intention to grant the patent | 25.04.2019 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 25.04.2019 | Fee for grant paid | 25.04.2019 | Fee for publishing/printing paid | 14.05.2019 | Information about intention to grant a patent | 14.05.2019 | Receipt of the translation of the claim(s) | Opposition(s) | 03.06.2020 | No opposition filed within time limit [2020/32] | Fees paid | Renewal fee | 02.01.2018 | Renewal fee patent year 03 | 02.01.2019 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 01.12.2015 | AL | 19.06.2019 | AT | 19.06.2019 | CY | 19.06.2019 | CZ | 19.06.2019 | DK | 19.06.2019 | EE | 19.06.2019 | ES | 19.06.2019 | FI | 19.06.2019 | HR | 19.06.2019 | IT | 19.06.2019 | LT | 19.06.2019 | LV | 19.06.2019 | MC | 19.06.2019 | MK | 19.06.2019 | MT | 19.06.2019 | NL | 19.06.2019 | PL | 19.06.2019 | RO | 19.06.2019 | RS | 19.06.2019 | SE | 19.06.2019 | SI | 19.06.2019 | SK | 19.06.2019 | SM | 19.06.2019 | TR | 19.06.2019 | BG | 19.09.2019 | NO | 19.09.2019 | GR | 20.09.2019 | IS | 19.10.2019 | PT | 21.10.2019 | IE | 01.12.2019 | LU | 01.12.2019 | BE | 31.12.2019 | CH | 31.12.2019 | LI | 31.12.2019 | [2022/31] |
Former [2021/34] | HU | 01.12.2015 | |
AL | 19.06.2019 | ||
AT | 19.06.2019 | ||
CY | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
MT | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
IE | 01.12.2019 | ||
LU | 01.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2021/33] | HU | 01.12.2015 | |
AL | 19.06.2019 | ||
AT | 19.06.2019 | ||
CY | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
IE | 01.12.2019 | ||
LU | 01.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2021/26] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CY | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
IE | 01.12.2019 | ||
LU | 01.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2020/51] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
IE | 01.12.2019 | ||
LU | 01.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2020/46] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
IE | 01.12.2019 | ||
LU | 01.12.2019 | ||
Former [2020/39] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
MC | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/37] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SI | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/36] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/24] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
PL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
PT | 21.10.2019 | ||
IS | 24.02.2020 | ||
Former [2020/22] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
DK | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/17] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
TR | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/13] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
SM | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/12] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
IT | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
IS | 19.10.2019 | ||
PT | 21.10.2019 | ||
Former [2020/11] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
EE | 19.06.2019 | ||
ES | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
SK | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
PT | 21.10.2019 | ||
Former [2020/10] | AL | 19.06.2019 | |
AT | 19.06.2019 | ||
CZ | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RO | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
PT | 21.10.2019 | ||
Former [2020/09] | AL | 19.06.2019 | |
CZ | 19.06.2019 | ||
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
Former [2020/07] | AL | 19.06.2019 | |
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
NL | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
Former [2019/51] | AL | 19.06.2019 | |
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
BG | 19.09.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
Former [2019/50] | AL | 19.06.2019 | |
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
LV | 19.06.2019 | ||
RS | 19.06.2019 | ||
SE | 19.06.2019 | ||
NO | 19.09.2019 | ||
GR | 20.09.2019 | ||
Former [2019/49] | AL | 19.06.2019 | |
FI | 19.06.2019 | ||
HR | 19.06.2019 | ||
LT | 19.06.2019 | ||
SE | 19.06.2019 | ||
NO | 19.09.2019 | ||
Former [2019/48] | FI | 19.06.2019 | |
LT | 19.06.2019 | ||
SE | 19.06.2019 | ||
NO | 19.09.2019 | ||
Former [2019/47] | FI | 19.06.2019 | |
LT | 19.06.2019 | ||
NO | 19.09.2019 | Cited in | International search | [A]WO2013041591 (HOFFMANN LA ROCHE [CH], et al) [A] 1-12 * the whole document *; | [A]WO2013156423 (HOFFMANN LA ROCHE [CH], et al) [A] 1-12* the whole document *; | [A]WO2014179186 (BOEHRINGER INGELHEIM INT [DE], et al) [A] 1-12 * the whole document * | by applicant | - D. W. GOOD, HYPERTENSION, (2007), vol. 49, pages 728 - 739 | - FIEBLER ET AL., CIRCULATION, (2005), vol. 111, pages 3087 - 3094 | - LEA ET AL., KIDNEY INTERNATIONAL, (2009), vol. 75, pages 936 - 945 | - E. J. LEWIS ET AL., N. ENGL. J. MED., (2001), vol. 345, pages 851 - 860 | - B.M. BRENNER ET AL., N. ENGL. J. MED., (2001), vol. 345, pages 861 - 869 | - BIRGE, S.M. ET AL., J. PHARM. SCI., (1977), vol. 66, pages 1 - 19 | - J.D. MCGARRY ET AL., BIOCHEM. J., (1983), vol. 214, pages 21 - 28 | - R. YAMAGUCHI ET AL., CELL DEATH AND DIFFERENTIATION, (2007), vol. 14, pages 616 - 624 |