EP3237430 - PRODRUGS OF 17ß -HSD1 -INHIBITORS [Right-click to bookmark this link] | |||
Former [2017/44] | PRODRUGS OF 17 -HSD1 -INHIBITORS | ||
[2019/12] | Status | No opposition filed within time limit Status updated on 24.01.2020 Database last updated on 16.11.2024 | |
Former | The patent has been granted Status updated on 15.02.2019 | ||
Former | Grant of patent is intended Status updated on 10.10.2018 | ||
Former | Request for examination was made Status updated on 29.09.2017 | ||
Former | The international publication has been made Status updated on 19.07.2017 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Forendo Pharma Ltd Itäinen Pitkäkatu 4 B 20520Turku / FI | [2017/44] | Inventor(s) | 01 /
HIRVELÄ, Leena c/o Forendo Pharma Ltd. Itäinen Pitkäkatu 4 B 20520 Turku / FI | 02 /
KOSKIMIES, Pasi c/o Forendo Pharma Ltd. Itäinen Pitkäkatu 4 B 20520 Turku / FI | 03 /
LAMMINTAUSTA, Risto c/o Forendo Pharma Ltd. Itäinen Pitkäkatu 4 B 20520 Turku / FI | 04 /
HAKOLA, Marjo c/o Forendo Pharma Ltd. Itäinen Pitkäkatu 4 B 20520 Turku / FI | 05 /
ELORANTA, Maire c/o Forendo Pharma Ltd. Itäinen Pitkäkatu 4 B 20520 Turku / FI | [2017/44] | Representative(s) | Kolster Oy Ab (Salmisaarenaukio 1) P.O. Box 204 00181 Helsinki / FI | [2017/44] | Application number, filing date | 15828339.0 | 22.12.2015 | [2017/44] | WO2015FI50928 | Priority number, date | FI20140006149 | 23.12.2014 Original published format: FI 20146149 | [2017/44] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016102775 | Date: | 30.06.2016 | Language: | EN | [2016/26] | Type: | A1 Application with search report | No.: | EP3237430 | Date: | 01.11.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 30.06.2016 takes the place of the publication of the European patent application. | [2017/44] | Type: | B1 Patent specification | No.: | EP3237430 | Date: | 20.03.2019 | Language: | EN | [2019/12] | Search report(s) | International search report - published on: | EP | 30.06.2016 | Classification | IPC: | C07J43/00, C07J51/00, A61K31/58, A61P35/00, A61P5/24 | [2017/44] | CPC: |
C07J43/003 (EP,CN,US);
A61P13/02 (EP,US);
A61P17/02 (EP,US);
A61P19/02 (EP,US);
A61P27/12 (EP,US);
A61P3/04 (EP,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/44] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | PRODRUGS VON 17ß-HSD1-INHIBITOREN | [2019/12] | English: | PRODRUGS OF 17ß -HSD1 -INHIBITORS | [2019/12] | French: | PROMÉDICAMENTS D'INHIBITEURS DE 17ß -HSD1 | [2019/12] |
Former [2017/44] | PRODRUGS VON 17-HSD1-INHIBITOREN | ||
Former [2017/44] | PRODRUGS OF 17 -HSD1 -INHIBITORS | ||
Former [2017/44] | PROMÉDICAMENTS D'INHIBITEURS DE 17 -HSD1 | Entry into regional phase | 18.07.2017 | National basic fee paid | 18.07.2017 | Designation fee(s) paid | 18.07.2017 | Examination fee paid | Examination procedure | 18.07.2017 | Examination requested [2017/44] | 18.07.2017 | Date on which the examining division has become responsible | 02.03.2018 | Amendment by applicant (claims and/or description) | 11.10.2018 | Communication of intention to grant the patent | 01.02.2019 | Fee for grant paid | 01.02.2019 | Fee for publishing/printing paid | 01.02.2019 | Receipt of the translation of the claim(s) | Opposition(s) | 02.01.2020 | No opposition filed within time limit [2020/09] | Fees paid | Renewal fee | 29.12.2017 | Renewal fee patent year 03 | 18.12.2018 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 22.12.2015 | AL | 20.03.2019 | AT | 20.03.2019 | CY | 20.03.2019 | CZ | 20.03.2019 | DK | 20.03.2019 | EE | 20.03.2019 | ES | 20.03.2019 | FI | 20.03.2019 | HR | 20.03.2019 | IT | 20.03.2019 | LT | 20.03.2019 | LV | 20.03.2019 | MC | 20.03.2019 | MK | 20.03.2019 | MT | 20.03.2019 | NL | 20.03.2019 | PL | 20.03.2019 | RO | 20.03.2019 | RS | 20.03.2019 | SE | 20.03.2019 | SI | 20.03.2019 | SK | 20.03.2019 | SM | 20.03.2019 | TR | 20.03.2019 | BG | 20.06.2019 | NO | 20.06.2019 | GR | 21.06.2019 | IS | 20.07.2019 | PT | 20.07.2019 | IE | 22.12.2019 | LU | 22.12.2019 | BE | 31.12.2019 | CH | 31.12.2019 | LI | 31.12.2019 | [2022/32] |
Former [2021/34] | HU | 22.12.2015 | |
AL | 20.03.2019 | ||
AT | 20.03.2019 | ||
CY | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
MT | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
IE | 22.12.2019 | ||
LU | 22.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2021/32] | HU | 22.12.2015 | |
AL | 20.03.2019 | ||
AT | 20.03.2019 | ||
CY | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
IE | 22.12.2019 | ||
LU | 22.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2021/26] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CY | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
IE | 22.12.2019 | ||
LU | 22.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2020/51] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
IE | 22.12.2019 | ||
LU | 22.12.2019 | ||
BE | 31.12.2019 | ||
CH | 31.12.2019 | ||
LI | 31.12.2019 | ||
Former [2020/46] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
IE | 22.12.2019 | ||
LU | 22.12.2019 | ||
Former [2020/39] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
MC | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
Former [2020/17] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
TR | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
Former [2020/13] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SI | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
Former [2020/09] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
DK | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
Former [2020/04] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
IS | 20.07.2019 | ||
PT | 20.07.2019 | ||
Former [2020/03] | AL | 20.03.2019 | |
AT | 20.03.2019 | ||
CZ | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
PT | 20.07.2019 | ||
Former [2019/52] | AL | 20.03.2019 | |
CZ | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
PL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
PT | 20.07.2019 | ||
Former [2019/51] | AL | 20.03.2019 | |
CZ | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
SM | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
PT | 20.07.2019 | ||
Former [2019/49] | AL | 20.03.2019 | |
CZ | 20.03.2019 | ||
EE | 20.03.2019 | ||
ES | 20.03.2019 | ||
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
RO | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
SK | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
PT | 20.07.2019 | ||
Former [2019/48] | ES | 20.03.2019 | |
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
PT | 20.07.2019 | ||
Former [2019/47] | ES | 20.03.2019 | |
FI | 20.03.2019 | ||
HR | 20.03.2019 | ||
IT | 20.03.2019 | ||
LT | 20.03.2019 | ||
LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
Former [2019/46] | FI | 20.03.2019 | |
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IT | 20.03.2019 | ||
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LV | 20.03.2019 | ||
NL | 20.03.2019 | ||
RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
Former [2019/39] | FI | 20.03.2019 | |
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LV | 20.03.2019 | ||
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RS | 20.03.2019 | ||
SE | 20.03.2019 | ||
BG | 20.06.2019 | ||
NO | 20.06.2019 | ||
GR | 21.06.2019 | ||
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NO | 20.06.2019 | Cited in | International search | [AD]WO2005047303 (SOLVAY PHARM GMBH [DE]) [AD] 1-21 * page 1, paragraph 1 * * page 6, paragraph l - page 7, paragraph 2 * * page 111; example 329 * * page 113; example 329A * * page 158; example 329; table 42 *; | [A]US2006281710 (MESSINGER JOSEF [DE], et al) [A] 1-21 * page 86; example 9 * * pages 97-99; examples 2, 6, 30, 32, 34, 36-38, 40-42, 44 * * page 105; examples 163, 164 *; | [AD]WO2004085457 (STERIX LTD [GB], et al) [AD] 1-21 * page 9, paragraph l * * page 79, paragraph 2 * * page 256; compounds 338, 454 * * page 257; compound 515 *; | [ADP]WO2014207310 (FORENDO PHARMA LTD [FI]) [ADP] 1-21 * page 3, paragraphs 5-6 * * page 22; compound 58 * * page 26; compound 76 * * pages 32-33; compounds 100-104 * * pages 108-110; table 2 * * page 110; table 3 * | [A] - ALLAN G M ET AL, "Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 49, no. 4, doi:10.1021/JM050830T, ISSN 0022-2623, (20060223), pages 1325 - 1345, (20060126), XP002684169 [A] 1-21 * page 1333; table 3; compounds 5-8 * DOI: http://dx.doi.org/10.1021/jm050830t | Examination | WO2016102776 | by applicant | WO0142181 | WO03022835 | WO03033487 | WO2004046111 | WO2004060488 | WO2004110459 | WO2005032527 | WO2005084295 | WO2004085457 | WO2006003012 | WO2006003013 | WO2004085345 | WO2006027347 | WO2005047303 | WO2008034796 | WO9946279 | WO2006125800 | WO0007996 | US2003170292 | - POIRIER D., CURR MED CHEM, (2003), vol. 10, pages 453 - 77 | - POIRIER D., EXPERT OPIN. THER. PATENTS, (2010), vol. 20, no. 9, pages 1123 - 1145 | - MESSINGER ET AL., MOL CELL ENDOCRINOL., (2009), pages 216 - 224 | - PURANEN, T.J.; POUTANEN, M.H.; PELTOKETO, H.E.; VIHKO, P.T.; VIHKO, R.K., "Site-directed mutagenesis of the putative active site of human 17 p-hydroxysteroid dehydrogenase type 1", BIOCHEM. J., (1994), vol. 304, pages 289 - 293 |