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Extract from the Register of European Patents

EP About this file: EP3186247

EP3186247 - PROTEIN KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.01.2022
Database last updated on 31.08.2024
FormerThe patent has been granted
Status updated on  29.01.2021
FormerGrant of patent is intended
Status updated on  13.10.2020
FormerExamination is in progress
Status updated on  02.03.2018
FormerRequest for examination was made
Status updated on  02.06.2017
FormerThe international publication has been made
Status updated on  25.03.2017
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK		published on 29.05.2024  [2024/22]
Applicant(s)For all designated states
Astar Biotech LLC
800E. Leigh Street Suite 53
Virginia Biotech Center
Richmond, VA 23219 / US
[2017/27]
Inventor(s)01 / YU, Chunrong
800E. Leigh Street
Suite 53
Richmond, Virginia 23219 / US
02 / HUANG, Haihong
Institute of Materia Medica
CAMS & PUMC.
1 Xian Nong Tan Street
Beijing 100050 / CN
03 / ZHANG, Dongfeng
Institute of Materia Medica
CAMS & PUMC.
1 Xian Nong Tan Street
Beijing 100050 / CN
04 / LI, Peng
Institute of Materia Medica
CAMS & PUMC.
1 Xian Nong Tan Street
Beijing 100050 / CN
 [2017/27]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2017/27]
Application number, filing date15834916.730.07.2015
[2017/27]
WO2015CN85600
Priority number, dateUS20141446915626.08.2014         Original published format: US201414469156
[2017/27]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016029776
Date:03.03.2016
Language:EN
[2016/09]
Type: A1 Application with search report 
No.:EP3186247
Date:05.07.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 03.03.2016 takes the place of the publication of the European patent application.
[2017/27]
Type: B1 Patent specification 
No.:EP3186247
Date:03.03.2021
Language:EN
[2021/09]
Search report(s)International search report - published on:CN03.03.2016
(Supplementary) European search report - dispatched on:EP10.05.2017
ClassificationIPC:A61P35/00, C07D403/12, C07D403/10, C07D237/20, C07D239/42, C07D498/04, A61P11/06, A61P19/02, A61P29/00, A61P35/02, A61P43/00
[2020/43]
CPC:
C07D498/04 (EP); A61P11/06 (EP); A61P19/02 (EP);
A61P29/00 (EP); A61P35/00 (EP); A61P35/02 (EP);
A61P43/00 (EP); C07D237/20 (EP); C07D239/42 (EP);
C07D403/10 (EP); C07D403/12 (EP) (-)
Former IPC [2017/27]C07D471/00, A61P35/00, C07D403/12, C07D403/10, C07D237/20, C07D239/42, C07D498/04
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/27]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
TitleGerman:PROTEINKINASEHEMMER[2017/27]
English:PROTEIN KINASE INHIBITORS[2017/27]
French:INHIBITEURS DE PROTÉINE KINASE[2017/27]
Entry into regional phase24.03.2017National basic fee paid 
24.03.2017Search fee paid 
24.03.2017Designation fee(s) paid 
24.03.2017Examination fee paid 
Examination procedure24.03.2017Examination requested  [2017/27]
24.03.2017Date on which the examining division has become responsible
29.11.2017Amendment by applicant (claims and/or description)
02.03.2018Despatch of a communication from the examining division (Time limit: M04)
18.06.2018Reply to a communication from the examining division
21.12.2018Despatch of a communication from the examining division (Time limit: M04)
05.04.2019Reply to a communication from the examining division
13.05.2019Despatch of a communication from the examining division (Time limit: M02)
18.07.2019Reply to a communication from the examining division
12.08.2019Despatch of a communication from the examining division (Time limit: M04)
22.10.2019Reply to a communication from the examining division
29.11.2019Despatch of a communication from the examining division (Time limit: M04)
30.03.2020Reply to a communication from the examining division
22.06.2020Despatch of a communication from the examining division (Time limit: M04)
04.09.2020Reply to a communication from the examining division
14.10.2020Communication of intention to grant the patent
20.01.2021Fee for grant paid
20.01.2021Fee for publishing/printing paid
20.01.2021Receipt of the translation of the claim(s)
Opposition(s)06.12.2021No opposition filed within time limit [2022/06]
Fees paidRenewal fee
28.07.2017Renewal fee patent year 03
27.07.2018Renewal fee patent year 04
30.07.2019Renewal fee patent year 05
24.07.2020Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.07.2015
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
MK03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
IE30.07.2021
LU30.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
[2024/22]
Former [2023/30]HU30.07.2015
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
IE30.07.2021
LU30.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
Former [2023/29]HU30.07.2015
AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
IE30.07.2021
LU30.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
Former [2022/35]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
IE30.07.2021
LU30.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
Former [2022/34]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
LU30.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
Former [2022/23]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
IT03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
LU30.07.2021
CH31.07.2021
LI31.07.2021
Former [2022/21]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
CH31.07.2021
LI31.07.2021
Former [2022/18]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2022/13]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2022/10]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2022/08]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
ES03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2022/07]AL03.03.2021
AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2021/51]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2021/50]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2021/48]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/46]AT03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/43]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/39]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/38]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/37]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
RS03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/36]FI03.03.2021
HR03.03.2021
LT03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/35]FI03.03.2021
HR03.03.2021
LT03.03.2021
NO03.06.2021
Former [2021/33]FI03.03.2021
LT03.03.2021
NO03.06.2021
Documents cited:Search[I]WO2012089106  (SUN SHUPING [CN]) [I] 1-11 * claim 1 for R4 is halogen *;
 [I]CN102775411  (ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD) [I] 1-11* claims 1-14, especially compounds of claims 4; *;
 [I]WO2014019338  (ASTAR BIOTECH LLC [US], et al) [I] 1-11 * compounds VII of claim 8; examples 36 and 37 on pages 70 and 71 *
International search[A]WO0146124  (NIHON NOHYAKU CO LTD [JP], et al) [A] 1-11* Abstract, Description paragraph [0046] *;
 [A]WO2013184681  (ARAGON PHARMACEUTICALS INC [US], et al) [A] 1-11 * Description page 48 compound 300, compound 301 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.