EP3191447 - S-IMINO-S-OXO IMINOTHIAZINE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.03.2020 Database last updated on 24.07.2024 | |
Former | The patent has been granted Status updated on 29.03.2019 | ||
Former | Grant of patent is intended Status updated on 18.11.2018 | ||
Former | Request for examination was made Status updated on 16.06.2017 | ||
Former | The international publication has been made Status updated on 01.04.2017 | Most recent event Tooltip | 08.07.2022 | Lapse of the patent in a contracting state New state(s): MK | published on 10.08.2022 [2022/32] | Applicant(s) | For all designated states Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2017/29] | Inventor(s) | 01 /
CUMMING, Jared N. 2000 Galloping Hill Road Kenilworth, New Jersey 07033 / US | 02 /
SCOTT, Jack D. 2000 Galloping Hill Road Kenilworth, New Jersey 07033 / US | [2017/29] | Representative(s) | Jaap, David Robert, et al Merck Sharp & Dohme Corp. 120 Moorgate London, EC2M 6UR / GB | [N/P] |
Former [2017/29] | Jaap, David Robert, et al Merck Sharp & Dohme Corp. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | Application number, filing date | 15840606.6 | 08.09.2015 | [2017/29] | WO2015US48786 | Priority number, date | US201462049471P | 12.09.2014 Original published format: US 201462049471 P | [2017/29] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2016040226 | Date: | 17.03.2016 | Language: | EN | [2016/11] | Type: | A1 Application with search report | No.: | EP3191447 | Date: | 19.07.2017 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.03.2016 takes the place of the publication of the European patent application. | [2017/29] | Type: | B1 Patent specification | No.: | EP3191447 | Date: | 01.05.2019 | Language: | EN | [2019/18] | Search report(s) | International search report - published on: | US | 17.03.2016 | (Supplementary) European search report - dispatched on: | EP | 12.02.2018 | Classification | IPC: | C07D471/04, C07D417/12, A61K31/541, A61P25/28 | [2018/11] | CPC: |
C07D471/04 (EP,US);
A61P25/28 (EP);
C07D417/12 (EP,US)
|
Former IPC [2017/29] | C07C335/32, C07C309/14, C07D295/088 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2017/29] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | Title | German: | S-IMINO-S-OXO-IMINOTHIAZIN-VERBINDUNGEN ALS BACE-HEMMER, ZUSAMMENSETZUNGEN UND DEREN VERWENDUNG | [2017/29] | English: | S-IMINO-S-OXO IMINOTHIAZINE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | [2017/29] | French: | COMPOSÉS DE S-IMINO-S-OXO IMINOTHIAZINE EN TANT QU'INHIBITEURS DE BACE, COMPOSITIONS, ET LEUR UTILISATION | [2017/29] | Entry into regional phase | 12.04.2017 | National basic fee paid | 12.04.2017 | Search fee paid | 12.04.2017 | Designation fee(s) paid | 12.04.2017 | Examination fee paid | Examination procedure | 31.03.2017 | Date on which the examining division has become responsible | 12.04.2017 | Examination requested [2017/29] | 06.09.2018 | Amendment by applicant (claims and/or description) | 19.11.2018 | Communication of intention to grant the patent | 19.03.2019 | Fee for grant paid | 19.03.2019 | Fee for publishing/printing paid | 19.03.2019 | Receipt of the translation of the claim(s) | Opposition(s) | 04.02.2020 | No opposition filed within time limit [2020/15] | Fees paid | Renewal fee | 11.09.2017 | Renewal fee patent year 03 | 11.09.2018 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 08.09.2015 | AL | 01.05.2019 | AT | 01.05.2019 | CY | 01.05.2019 | CZ | 01.05.2019 | DK | 01.05.2019 | EE | 01.05.2019 | ES | 01.05.2019 | FI | 01.05.2019 | HR | 01.05.2019 | IT | 01.05.2019 | LT | 01.05.2019 | LV | 01.05.2019 | MC | 01.05.2019 | MK | 01.05.2019 | MT | 01.05.2019 | NL | 01.05.2019 | PL | 01.05.2019 | RO | 01.05.2019 | RS | 01.05.2019 | SE | 01.05.2019 | SI | 01.05.2019 | SK | 01.05.2019 | SM | 01.05.2019 | TR | 01.05.2019 | BG | 01.08.2019 | NO | 01.08.2019 | GR | 02.08.2019 | IS | 01.09.2019 | PT | 01.09.2019 | IE | 08.09.2019 | LU | 08.09.2019 | BE | 30.09.2019 | CH | 30.09.2019 | LI | 30.09.2019 | [2022/32] |
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NO | 01.08.2019 | Documents cited: | Search | [ ] - No further relevant documents disclosed | International search | [A]US2014128382 (WU WEN-LIAN [US], et al) [A] 1-12 * , entire document, especially: *; | [A]US8729071 (SCOTT JACK D [US], et al) [A] 1-12 * , entire document. *; | [AP]WO2014150331 (MERCK SHARP & DOHME [US], et al) [AP] 1-12* , entire document, especially: abstract; Formula I. *; | [A] - OERLICH et al., "The evolution of amidine-based brain penetrant BACE1 inhibitors", Bioorganic & Medicinal Chemistry Letters., (20140300), vol. 24, doi:doi:10.1016/j.bmcl.2014.03.025, pages 2033 - 2045, XP055233028 [A] 1-12 * , entire document, especially: pg 2043, Figure 30. * DOI: http://dx.doi.org/10.1016/j.bmcl.2014.03.025 |