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Extract from the Register of European Patents

EP About this file: EP3214443

EP3214443 - RHEUMATOID ARTHRITIS MARKER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  29.03.2019
Database last updated on 03.09.2024
FormerRequest for examination was made
Status updated on  04.08.2017
FormerThe international publication has been made
Status updated on  27.03.2017
Most recent event   Tooltip29.03.2019Application deemed to be withdrawnpublished on 01.05.2019  [2019/18]
Applicant(s)For all designated states
National Institute of Advanced Industrial Science and Technology
3-1, Kasumigaseki 1-chome
Chiyoda-ku
Tokyo 100-8921 / JP
For all designated states
Keio University
15-45 Mita 2-chome Minato-ku
Tokyo 108-8345 / JP
For all designated states
GlycoBiomarker Leading Innovation Co., Ltd.
Central 2, 1-1-1, Umezono
Tsukuba-shi
Ibaraki 305-8568 / JP
[2017/36]
Inventor(s)01 / KUNO, Atsushi
c/o National Institute of Advanced Industrial
Science and Technology
Tsukuba Central 2
1-1 Umezono 1-chome
Tsukuba-shi Ibaraki 305-8568 / JP
02 / MATSUDA, Atsushi
c/o National Institute of Advanced Industrial
Science and Technology
Tsukuba Central 2
1-1 Umezono 1-chome
Tsukuba-shi Ibaraki 305-8568 / JP
03 / NARIMATSU, Hisashi
c/o National Institute of Advanced Industrial
Science and Technology
Tsukuba Central 2
1-1, Umezono 1-chome
Tsukuba-shi Ibaraki 3058568 / JP
04 / TAKEUCHI, Tsutomu
c/o School of Medicine
Keio University
35 Shinanomachi
Shinjuku-ku
Tokyo 160-8582 / JP
05 / SUZUKI, Katsuya
c/o School of Medicine
Keio University
35 Shinanomachi
Shinjuku-ku
Tokyo 160-8582 / JP
06 / TAKESHITA, Masaru
c/o School of Medicine
Keio University
35 Shinanomachi
Shinjuku-ku
Tokyo 160-8582 / JP
 [2017/36]
Representative(s)Ladendorf, Oliver
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[2017/36]
Application number, filing date15854205.029.10.2015
[2017/36]
WO2015JP80522
Priority number, dateJP2014022209630.10.2014         Original published format: JP 2014222096
[2017/36]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016068226
Date:06.05.2016
Language:JA
[2016/18]
Type: A1 Application with search report 
No.:EP3214443
Date:06.09.2017
Language:EN
[2017/36]
Search report(s)International search report - published on:JP06.05.2016
(Supplementary) European search report - dispatched on:EP05.04.2018
ClassificationIPC:G01N33/564, C07K14/42, C12N9/64, G01N33/53, G01N33/573, C07K16/40
[2018/18]
CPC:
G01N33/573 (EP,US); C07K14/42 (EP,US); C07K16/40 (US);
C12N9/64 (EP,US); C12Y304/24017 (US); G01N33/53 (EP,US);
G01N33/564 (EP,US); G01N2333/96494 (US); G01N2800/102 (US) (-)
Former IPC [2017/36]G01N33/564, C07K14/42, C12N9/64, G01N33/53, G01N33/573
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/36]
TitleGerman:MARKER FÜR RHEUMATOIDE ARTHRITIS[2017/36]
English:RHEUMATOID ARTHRITIS MARKER[2017/36]
French:MARQUEUR DE L'ARTHRITE RHUMATOÏDE[2017/36]
Entry into regional phase09.05.2017Translation filed 
09.05.2017National basic fee paid 
09.05.2017Search fee paid 
09.05.2017Designation fee(s) paid 
09.05.2017Examination fee paid 
Examination procedure09.05.2017Amendment by applicant (claims and/or description)
09.05.2017Examination requested  [2017/36]
09.05.2017Date on which the examining division has become responsible
06.11.2018Application deemed to be withdrawn, date of legal effect  [2019/18]
14.12.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2019/18]
Fees paidRenewal fee
13.10.2017Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.10.201804   M06   Not yet paid
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Documents cited:Search[X]US2005186168  (ALBIN ERIC L [US]) [X] 3-6 * paragraph [0109] *;
 [X]  - ASKIN ATES ET AL, "Serum pro-matrix metalloproteinase-3 as an indicator of disease activity and severity in rheumatoid arthritis: comparison with traditional markers", RHEUMATOLOGY INTERNATIONAL ; CLINICAL AND EXPERIMENTAL INVESTIGATIONS, SPRINGER, BERLIN, DE, (20070411), vol. 27, no. 8, doi:10.1007/S00296-007-0338-1, ISSN 1437-160X, pages 715 - 722, XP019515063 [X] 3-6 * abstract *

DOI:   http://dx.doi.org/10.1007/s00296-007-0338-1
 [X]  - Atsushi Kuno ET AL, "Focused Differential Glycan Analysis with the Platform Antibody-assisted Lectin Profiling for Glycan-related Biomarker Verification", Molecular & Cellular Proteomics, United States, doi:10.1074/mcp.M800308-MCP200, (20080811), pages 99 - 108, URL: http://www.mcponline.org/content/8/1/99.abstract, (20180321), XP055186351 [X] 7,8,15 * abstract * * figure 4 *

DOI:   http://dx.doi.org/10.1074/mcp.M800308-MCP200
 [X]  - ASHISH SAROHA ET AL, "Jacalin Bound Plasma O-Glycoproteome and Reduced Sialylation of Alpha 2-HS Glycoprotein (A2HSG) in Rheumatoid Arthritis Patients", PLOS ONE, (20121003), vol. 7, no. 10, doi:10.1371/journal.pone.0046374, page e46374, XP055192372 [X] 8,15 * abstract *

DOI:   http://dx.doi.org/10.1371/journal.pone.0046374
 [X]  - KOJI IMAMURA ET AL, "Engineering of the glycan-binding specificity of Agrocybe cylindracea galectin towards [alpha](2,3)-linked sialic acid by saturation mutagenesis", JOURNAL OF BIOCHEMISTRY, GB, (20110803), vol. 150, no. 5, doi:10.1093/jb/mvr094, ISSN 0021-924X, pages 545 - 552, XP055461654 [X] 7 * abstract *

DOI:   http://dx.doi.org/10.1093/jb/mvr094
 [X]  - YOSHIYUKI HIZUKURI ET AL, "Extraction of leukemia specific glycan motifs in humans by computational glycomics", CARBOHYDRATE RESEARCH, GB, (20050810), vol. 340, no. 14, doi:10.1016/j.carres.2005.07.012, ISSN 0008-6215, pages 2270 - 2278, XP055461662 [X] 7 * abstract *

DOI:   http://dx.doi.org/10.1016/j.carres.2005.07.012
International search[A]JPH10115618  (FUJI YAKUHIN KOGYO KK) [A] 1-38 * , paragraph [0028] (Family: none) *;
 [A]JP2864219B  (Fuji Chemical Industries, Ltd.) [A] 1-38 * , paragraph [0024] (Family: none) *;
 [A]WO2009096403  (UNIV HOKKAIDO NAT UNIV CORP [JP], et al) [A] 1-38 * , abstract & US 2010/0297682 A1 abstract & EP 2256499 A1 & EP 2535719 A2 *;
 [A]JP2013044657  (UNIV OSAKA) [A] 1-38 * , claim 6 (Family: none) *;
 [A]  - MICHIYO URATA et al., "A Basic Study of Determination Matrix Metalloproteinase-3 and Carbohydrate in Rheumatoid Factor in Serum for Diagnosis of Rheumatoid Arthritis", The Japanese Journal of Clinical Pathology, (20030000), vol. 51, no. 8, pages 745 - 750, XP 009502498 [A] 1-38
 [A]  - VAN DEN STEEN P E et al., "Matrix remodelling enzymes, the protease cascade and glycosylation", Biochim Biophys Acta, (20010000), vol. 1528, no. 2/3, doi:doi:10.1016/S0304-4165(01)00190-8, pages 61 - 73, XP 004312001 [A] 1-38 * , Fig. 4 *
 [A]  - SAARINEN J et al., "N-Glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells", Eur J Biochem, (19990000), vol. 259, no. 3, doi:doi:10.1046/j.1432-1327.1999.00105.x, pages 829 - 840, XP 002960515 [A] 1-38 * , Abstract *
 [A]  - SHUO T et al., "Detection of the heterogeneous O-glycosylation profile of MT1-MMP expressed in cancer cells by a simple MALDI-MS method", PLoS One, (20120000), vol. 7, no. 8, page e43751, XP 055436141 [A] 1-38 * , Abstract *
 [A]  - AKIRA TOGAYACHI et al., "Functional Analysis of beta1,3-N-Acetylglucosaminyltransferases and Regulation of Immunological Function by Polylactosamine", Trends Glycoscience Glycotechnology, (20120000), vol. 24, no. 137, pages 95 - 111, XP003032486 [A] 22-38
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