Extract from the Register of European Patents

EP About this file: EP3237621

EP3237621 - HUMAN ALPHA-GALACTOSIDASE VARIANTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.02.2024
Database last updated on 08.04.2026
FormerThe patent has been granted
Status updated on  17.03.2023
FormerGrant of patent is intended
Status updated on  26.10.2022
FormerExamination is in progress
Status updated on  13.06.2020
FormerRequest for examination was made
Status updated on  29.09.2017
FormerThe international publication has been made
Status updated on  21.07.2017
Most recent event   Tooltip23.02.2024No opposition filed within time limitpublished on 27.03.2024  [2024/13]
Applicant(s)For all designated states
Codexis, Inc.
200 Penobscot Drive
Redwood City, CA 94063 / US
[2017/44]
Inventor(s)01 / AGARD, Nicholas, J.
200 Penobscot Drive
Redwood City, California 94063 / US
02 / MILLER, Mathew, G.
200 Penobscot Drive
Redwood City, California 94063 / US
03 / ZHANG, Xiyun
34279 Maybird Circle
Fremont, California 94555 / US
04 / HUISMAN, Gjalt, W.
200 Penobscot Drive
Redwood City, California 94063 / US
 [2017/44]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2023/16]
Former [2017/44]Chapman, Desmond Mark
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Application number, filing date15874075.302.12.2015
[2017/44]
WO2015US63329
Priority number, dateUS201462095313P22.12.2014         Original published format: US 201462095313 P
US201562216452P10.09.2015         Original published format: US 201562216452 P
[2017/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016105889
Date:30.06.2016
Language:EN
[2016/26]
Type: A1 Application with search report 
No.:EP3237621
Date:01.11.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 30.06.2016 takes the place of the publication of the European patent application.
[2017/44]
Type: B1 Patent specification 
No.:EP3237621
Date:19.04.2023
Language:EN
[2023/16]
Search report(s)International search report - published on:US30.06.2016
(Supplementary) European search report - dispatched on:EP26.10.2018
ClassificationIPC:C12N15/56, A61K38/47, C07K14/47, C12N9/24, A61P3/00, A61P3/06
[2018/33]
CPC:
A61K38/47 (EP,IL,KR,US); C12N9/2465 (EP,IL,KR,US); A61K38/00 (IL);
A61K9/0019 (IL,US); A61P3/00 (EP,KR); A61P3/06 (EP);
A61P43/00 (EP); C12N15/79 (KR); C12Y302/01022 (EP,IL,KR,US) (-)
Former IPC [2017/44]C12N15/56, A61K38/47, C07K14/47, C12N9/24
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/44]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VARIANTEN VON MENSCHLICHER ALPHA-GALACTOSIDASE[2017/44]
English:HUMAN ALPHA-GALACTOSIDASE VARIANTS[2017/44]
French:VARIANTS D'ALPHA-GALACTOSIDASE HUMAINE[2017/44]
Entry into regional phase21.07.2017National basic fee paid 
21.07.2017Search fee paid 
21.07.2017Designation fee(s) paid 
21.07.2017Examination fee paid 
Examination procedure21.07.2017Examination requested  [2017/44]
21.07.2017Date on which the examining division has become responsible
20.05.2019Amendment by applicant (claims and/or description)
17.06.2020Despatch of a communication from the examining division (Time limit: M04)
18.09.2020Reply to a communication from the examining division
15.01.2021Despatch of a communication from the examining division (Time limit: M06)
22.07.2021Reply to a communication from the examining division
07.09.2021Despatch of a communication from the examining division (Time limit: M06)
15.03.2022Reply to a communication from the examining division
27.10.2022Communication of intention to grant the patent
03.03.2023Fee for grant paid
03.03.2023Fee for publishing/printing paid
03.03.2023Receipt of the translation of the claim(s)
Divisional application(s)EP23168236.0  / EP4234699
Opposition(s)22.01.2024No opposition filed within time limit [2024/13]
Fees paidRenewal fee
27.12.2017Renewal fee patent year 03
31.12.2018Renewal fee patent year 04
27.12.2019Renewal fee patent year 05
28.12.2020Renewal fee patent year 06
16.12.2021Renewal fee patent year 07
20.12.2022Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL19.04.2023
SM19.04.2023
[2024/12]
Former [2024/08]SM19.04.2023
Documents cited:Search[XY] US2012328592  (SHULMAN AVIDOR et al.) [X] 1,4-15 * the whole document * * sequence 15 *[Y] 1,4-15
 [XY] WO2013156552  (VIB VZW et al.) [X] 1,4-15 * abstract * * sequence 1 *[Y] 1,4-15
International search[X] US2011280856  (SELDEN RICHARD F et al.) [X] 1-2, 4/(1-2) * para [0014], [0050]; SEQ ID NO: 4 *
 [L] US5356804  (DESNICK ROBERT J et al.) [L] 2, 4/2 * col 7, In 17-24; col 11, In 53-60; col 12, In 24-32 Incorporated by reference by Selden *
by applicantUS2011280856
 US5356804
 US2012328592
 WO2013156552
 US6117679
 US6420175
 US6376246
 US6586182
 US7747391
 US7747393
 US7783428
 US8383346
 WO9600787
 WO9522625
 WO9700078
 WO9735966
 WO9827230
 WO0042651
 WO0175767
 US6537746
 US5605793
 US5811238
 US5830721
 US5834252
 US5837458
 US5928905
 US6096548
 US6132970
 US6165793
 US6180406
 US6251674
 US6277638
 US6287861
 US6287862
 US6291242
 US6297053
 US6303344
 US6309883
 US6319713
 US6319714
 US6323030
 US6326204
 US6335160
 US6335198
 US6344356
 US6352859
 US6355484
 US6358740
 US6358742
 US6365377
 US6365408
 US6368861
 US6372497
 US6379964
 US6387702
 US6391552
 US6391640
 US6395547
 US6406855
 US6406910
 US6413745
 US6413774
 US6423542
 US6426224
 US6436675
 US6444468
 US6455253
 US6479652
 US6482647
 US6489146
 US6506602
 US6506603
 US6519065
 US6521453
 US6528311
 US6573098
 US6576467
 US6579678
 US6602986
 US6613514
 US6653072
 US6716631
 US6946296
 US6961664
 US6995017
 US7024312
 US7058515
 US7105297
 US7148054
 US7288375
 US7421347
 US7430477
 US7534564
 US7620500
 US7620502
 US7629170
 US7702464
 US7751986
 US7776598
 US7795030
 US7853410
 US7868138
 US7873499
 US7904249
 US7957912
 US8504498
 US8849575
 US8876066
 US8768871
 US2008220990
 US2009312196
 US2014005057
 US2014214391
 US2014221216
 US2015050658
 US2015133307
 US2015134315
 WO2009152336
 US7531341
 US7534595
 US7560263
 US2013039898
 US2012177722
 WO2010144103
   NANCE ET AL., ARCH. NEUROL., vol. 63, 2006, pages 453 - 457
   SCHIFFMANN, PHARM. THER., vol. 122, 2009, pages 65 - 77
   WANT ET AL., GENET. MED., vol. 13, 2011, pages 457 - 484
   SMITHWATERMAN, ADV. APPL. MATH., vol. 2, 1981, pages 482
   NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443
   PEARSONLIPMAN, PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
   ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
   ALTSCHUL ET AL., NUCLEIC ACIDS RES., 1977, pages 3389 - 3402
   HENIKOFFHENIKOFF, PROC. NATL. ACAD. SCI. USA, vol. 89, 1989, pages 10915
   ROMANOS ET AL., YEAST, vol. 8, 1992, pages 423 - 488
   GUOSHERMAN, MOL. CELL. BIO., vol. 15, 1995, pages 5983 - 5990
   STEMMER, PROC. NATL. ACAD. SCI. USA, vol. 91, 1994, pages 10747 - 10751
   ZHAO ET AL., NAT. BIOTECHNOL., vol. 16, 1998, pages 258 - 261
   CALDWELL ET AL., PCR METHODS APPL., vol. 3, 1994, pages S136 - S140
   BLACK ET AL., PROC. NATL. ACAD. SCI. USA, vol. 93, 1996, pages 3525 - 3529
   LING ET AL., ANAL. BIOCHEM., vol. 254, no. 2, 1997, pages 157 - 78
   DALE ET AL., METH. MOL. BIOL., vol. 57, 1996, pages 369 - 74
   SMITH, ANN. REV. GENET., vol. 19, 1985, pages 423 - 462
   BOTSTEIN ET AL., SCIENCE, vol. 229, 1985, pages 1193 - 1201
   CARTER, BIOCHEM. J., vol. 237, 1986, pages 1 - 7
   KRAMER ET AL., CELL, vol. 38, 1984, pages 879 - 887
   WELLS ET AL., GENE, vol. 34, 1985, pages 315 - 323
   MINSHULL ET AL., CURR. OP. CHEM. BIOL., vol. 3, 1999, pages 284 - 290
   CHRISTIANS ET AL., NAT. BIOTECHNOL., vol. 17, 1999, pages 259 - 264
   CRAMERI ET AL., NATURE, vol. 391, 1998, pages 288 - 291
   CRAMERI ET AL., NAT. BIOTECHNOL., vol. 15, 1997, pages 436 - 438
   ZHANG ET AL., PROC. NAT. ACAD. SCI. U.S.A., vol. 94, 1997, pages 4504 - 4509
   CRAMERI ET AL., NAT. BIOTECHNOL., vol. 14, 1996, pages 315 - 319
   STEMMER, NATURE, vol. 370, 1994, pages 389 - 391
   STEMMER, PROC. NAT. ACAD. SCI. USA, vol. 91, 1994, pages 10747 - 10751
   BEAUCAGE ET AL., TETRA. LETT., vol. 22, 1981, pages 1859 - 69
   MATTHES ET AL., EMBO J., vol. 3, 1984, pages 801 - 05
   IKEDA, AMINO ACIDS, vol. 29, 2005, pages 283 - 287
   MCLLVAINE, J. BIOL. CHEM., vol. 49, 1921, pages 183 - 186
   YASUDA ET AL., PROT. EXP. PUR, vol. 37, 2004, pages 499 - 506
   VITA ET AL., NUCL. ACIDS RES., vol. 38, 2010, pages D854 - 62
   SOUTHWOOD ET AL., J. IMMUNOL., vol. 160, 1998, pages 3363 - 3373
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.