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EP About this file: EP3271329

EP3271329 - NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 24.06.2022 Database last updated on 05.10.2024
Former	The patent has been granted Status updated on 16.07.2021
Former	Grant of patent is intended Status updated on 03.03.2021
Former	Examination is in progress Status updated on 03.12.2019
Former	Request for examination was made Status updated on 28.12.2017
Former	The international publication has been made Status updated on 11.11.2016
Most recent event Tooltip	13.09.2024	Lapse of the patent in a contracting state New state(s): MT	published on 16.10.2024 [2024/42]
Applicant(s)	For all designated states Hangzhou Dac Biotech Co., Ltd Building 12, ZhengTaiZhongZi Technology Park No. 260 Sixth Street, HEDA Hangzhou City, Zhejiang Province 310018 / CN
	[2018/04]
Inventor(s)	01 / SUN, Sanxing 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	02 / ZHAO, Robert Yongxin 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	03 / LI, Xing 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	04 / GUO, Huihui 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	05 / JIA, Junxiang 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	06 / XIE, Hongsheng 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	07 / ZHOU, Xiaomai 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	08 / HUANG, Yuanyuan 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	09 / YANG, Qingliang 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	10 / ZHUO, Xiaotao 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	11 / YE, Hangbo 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	12 / GAI, Shun 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	13 / QU, Lan 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	14 / LI, Wenjun 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	15 / LIN, Chen 452 Sixth Street Building 2 Room B2005 Hangzhou Zhejiang 310018 / CN
	[2018/04]
Representative(s)	Haseltine Lake Kempner LLP One Portwall Square Portwall Lane Bristol BS1 6BH / GB
	[N/P]
Former [2021/33]	Haseltine Lake Kempner LLP Redcliff Quay 120 Redcliff Street Bristol BS1 6HU / GB
Former [2018/04]	Haseltine Lake LLP Redcliff Quay 120 Redcliff Street Bristol BS1 6HU / GB
Application number, filing date	15885301.0	19.03.2015
	[2018/04]
	WO2015IB52011
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2016147031
	Date:	22.09.2016
	Language:	EN
	[2016/38]
	Type:	A2 Application without search report
	No.:	EP3271329
	Date:	24.01.2018
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 22.09.2016 takes the place of the publication of the European patent application.
	[2018/04]
	Type:	B1 Patent specification
	No.:	EP3271329
	Date:	18.08.2021
	Language:	EN
	[2021/33]
Search report(s)	International search report - published on:	CN	10.11.2016
	(Supplementary) European search report - dispatched on:	EP	28.03.2019
Classification	IPC:	A61K47/68, C07D207/404, C07D207/327, C07F9/6558, C07K16/28, A61P35/00, C07F9/572, C07K16/00, C07D207/46	[2021/10]
	CPC:	C07F9/572 (EP,US); A61K47/68033 (EP,US); A61K47/6811 (US); A61K47/6849 (US); A61K47/6851 (US); A61K47/6889 (US); (+) C07D207/46 (EP,US); C07F9/65583 (EP,US); C07K16/00 (US); C07K16/2878 (US) (-)
	Former IPC [2019/18]	C07D207/404, C07D207/327, C07F9/6558, C07K16/28, A61P35/00, C07F9/572, C07K16/00, C07D207/46, A61K47/68
	Former IPC [2018/04]	C07D207/404, C07D207/327, C07F9/38, C07K16/28, A61P35/00
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/04]
Extension states	BA	Not yet paid
	ME	Not yet paid
Validation states	MA	Not yet paid
Title	German:	NEUARTIGE HYDROPHILE LINKER UND LIGANDENARZNEIMITTELKONJUGATE DAVON	[2018/04]
	English:	NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF	[2018/04]
	French:	NOUVEAUX LIEURS HYDROPHILES ET CONJUGUÉS LIGAND-MÉDICAMENT LES COMPRENANT	[2018/04]
Entry into regional phase	08.09.2017	National basic fee paid
	08.09.2017	Search fee paid
	08.09.2017	Designation fee(s) paid
	08.09.2017	Examination fee paid
Examination procedure	08.09.2017	Examination requested [2018/04]
	08.09.2017	Date on which the examining division has become responsible
	24.10.2019	Amendment by applicant (claims and/or description)
	06.12.2019	Despatch of a communication from the examining division (Time limit: M02)
	14.02.2020	Reply to a communication from the examining division
	24.04.2020	Despatch of a communication from the examining division (Time limit: M02)
	23.06.2020	Reply to a communication from the examining division
	15.07.2020	Despatch of a communication from the examining division (Time limit: M02)
	11.09.2020	Reply to a communication from the examining division
	04.03.2021	Communication of intention to grant the patent
	12.07.2021	Fee for grant paid
	12.07.2021	Fee for publishing/printing paid
	12.07.2021	Receipt of the translation of the claim(s)
Divisional application(s)	EP21184933.6 / EP3912982
Opposition(s)	19.05.2022	No opposition filed within time limit [2022/30]
Fees paid	Renewal fee
	08.09.2017	Renewal fee patent year 03
	27.03.2018	Renewal fee patent year 04
	26.03.2019	Renewal fee patent year 05
	27.03.2020	Renewal fee patent year 06
	12.03.2021	Renewal fee patent year 07
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	AL	18.08.2021
	CY	18.08.2021
	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	MK	18.08.2021
	MT	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SI	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
	[2024/42]
Former [2024/22]	AL	18.08.2021
	CY	18.08.2021
	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	MK	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SI	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2024/20]	AL	18.08.2021
	CY	18.08.2021
	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SI	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/36]	AL	18.08.2021
	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SI	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/29]	AL	18.08.2021
	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/25]	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SK	18.08.2021
	SM	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/24]	CZ	18.08.2021
	EE	18.08.2021
	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RO	18.08.2021
	RS	18.08.2021
	SK	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/10]	HR	18.08.2021
	LT	18.08.2021
	LV	18.08.2021
	RS	18.08.2021
	BG	18.11.2021
	IS	18.12.2021
Former [2022/09]	LT	18.08.2021
	RS	18.08.2021
	BG	18.11.2021
Former [2022/08]	LT	18.08.2021
	BG	18.11.2021
Documents cited:	Search	[X]WO2006107175 (INKTEC CO LTD [KR], et al);
		[XI]WO2012143497 (BAYER IP GMBH [DE], et al);
		[X]US2013144541 (RYCHNOVSKY SCOTT [US], et al);
		[X]WO2014080251 (HANGZHOU DAC BIOTECH CO LTD [CN], et al);
		[XAI]WO2014151030 (NOVARTIS AG [CH], et al);
		[XAI]WO2015028850 (HANGZHOU DAC BIOTECH CO LTD [CN])
	International search	[A]WO2010126551 (IMMUNOGEN INC [US], et al);
		[X]WO2012143497 (BAYER IP GMBH [DE], et al);
		[X]WO2014080251 (HANGZHOU DAC BIOTECH CO LTD [CN], et al)
	Examination	EP3041846
	by applicant	WO2014080251
		WO2015028850

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