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Extract from the Register of European Patents

EP About this file: EP3112377

EP3112377 - BIFUNCTIONAL POLYPEPTIDES [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  06.08.2021
Database last updated on 17.07.2024
FormerThe patent has been granted
Status updated on  16.03.2018
FormerGrant of patent is intended
Status updated on  13.03.2018
FormerRequest for examination was made
Status updated on  06.02.2018
FormerGrant of patent is intended
Status updated on  25.09.2017
FormerRequest for examination was made
Status updated on  07.07.2017
FormerThe application has been published
Status updated on  02.12.2016
Most recent event   Tooltip06.08.2021Revocation of patentpublished on 08.09.2021  [2021/36]
Applicant(s)For all designated states
Immunocore Ltd.
101 Park Drive
Milton Park
Abingdon OX14 4RY
Oxfordshire / GB
[2017/01]
Inventor(s)01 / JAKOBSEN, Bent Karsten
Immunocore Limited
57 Jubilee Avenue
Milton Park
Abingdon, Oxfordshire OX14 4RX / GB
02 / VUIDEPOT, Annelise Brigitte
Immunocore Limited
57 Jubilee Avenue
Milton Park
Abingdon, Oxfordshire OX14 4RX / GB
03 / LI, Yi
Immunocore Limited
57 Jubilee Avenue
Milton Park
Abingdon, Oxfordshire OX14 4RX / GB
 [2017/01]
Representative(s)Lee, Nicholas John, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[2018/16]
Former [2017/01]Lee, Nicholas John, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date16176249.719.05.2010
[2017/01]
Priority number, dateGB2009000861320.05.2009         Original published format: GB 0908613
[2017/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3112377
Date:04.01.2017
Language:EN
[2017/01]
Type: B1 Patent specification 
No.:EP3112377
Date:18.04.2018
Language:EN
[2018/16]
Search report(s)(Supplementary) European search report - dispatched on:EP26.09.2016
ClassificationIPC:C07K14/705, C12N15/62, A61K38/17, // A61K38/00
[2017/01]
CPC:
A61K47/6849 (EP,US); A61K39/00114 (EP,US); A61K47/6425 (EP,US);
A61P31/04 (EP); A61P35/00 (EP); A61P35/02 (EP);
A61P37/00 (EP); A61P43/00 (EP); A61P9/00 (EP);
C07K14/54 (US); C07K14/7051 (EP,US); C07K16/2809 (EP,US);
C07K16/46 (EP,US); A61K38/00 (EP,US); C07K2317/622 (EP,US);
C07K2317/73 (EP,US); C07K2319/33 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2017/32]
Former [2017/01]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:BIFUNKTIONELLE POLYPEPTIDE[2017/01]
English:BIFUNCTIONAL POLYPEPTIDES[2017/01]
French:POLYPEPTIDES BIFONCTIONNELS[2017/01]
Examination procedure24.06.2016Date on which the examining division has become responsible
29.06.2017Amendment by applicant (claims and/or description)
29.06.2017Examination requested  [2017/32]
26.09.2017Communication of intention to grant the patent
05.02.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
05.02.2018Fee for grant paid
05.02.2018Fee for publishing/printing paid
13.03.2018Information about intention to grant a patent
13.03.2018Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP10720803.5  / EP2432802
Opposition(s)Opponent(s)01  15.01.2019  24.01.2019  ADMISSIBLE
Michalski Hüttermann & Partner Patentanwälte mbB
Speditionstraße 21
40221 Düsseldorf / DE
 [2021/16]
Former [2019/08]
Opponent(s)01  15.01.2019    ADMISSIBLE
Michalski Hüttermann & Partner Patentanwälte mbB
Speditionstraße 21
40221 Düsseldorf / DE
01.02.2019Invitation to proprietor to file observations on the notice of opposition
11.06.2019Reply of patent proprietor to notice(s) of opposition
03.06.2020Cancellation of oral proceeding that was planned for 22.07.2020
22.07.2020Date of oral proceedings
02.10.2020Cancellation of oral proceeding that was planned for 04.12.2020
04.12.2020Date of oral proceedings
19.03.2021Date of oral proceedings
19.03.2021Legal effect of revocation of patent [2021/36]
22.04.2021Despatch of minutes of oral proceedings
22.04.2021Despatch of communication that the patent will be revoked
Fees paidRenewal fee
24.06.2016Renewal fee patent year 03
24.06.2016Renewal fee patent year 04
24.06.2016Renewal fee patent year 05
24.06.2016Renewal fee patent year 06
24.06.2016Renewal fee patent year 07
30.05.2017Renewal fee patent year 08
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Patent Court
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO9960120  (AVIDEX LTD [GB], et al) [A] 1-9 * abstract ** page 15, lines 4-25 *;
 [X]WO0193913  (SUNOL MOLECULAR CORP [US]) [X] 1-9 * abstract * * page 3, lines 15-24 * * page 4, lines 4-7 * * page 5, line 12 - page 6, line 19 * * page 9, line 10 - page 10, line 11 * * page 14, lines 14-18 * * page 17, line 24 - page 19, line 2 * * examples 5-8,12 *;
 [X]WO03020763  (AVIDEX LTD [GB], et al) [X] 1-9 * abstract * * page 2, lines 4-21 * * page 5, line 24 - page 6, line 18 * * page 7, line 25 - page 8, line 22 * * page 11, line 18 - page 12, line 23 * * page 15, line 23 - page 16, line 2 * * page 16, line 26 - page 17, line 15 * * claims 1,11,18,19 *;
 [XY]WO2004074322  (AVIDEX LTD [GB], et al) [X] 1-4 * abstract * * page 4, line 18 - page 5, line 17 * * page 6, lines 4-12 * * page 9, line 18 - page 10, line 13 * * page 13, line 19 - page 14, line 13 * * page 14, lines 20-24 * * page 17, lines 27-30 * * page 19, lines 18,19 * * claims 1,11,12,18,19,21 * [Y] 5-9;
 [X]US2004253632  (RHODE PETER R [US], et al) [X] 1-9 * abstract * * paragraphs [0096] , [0098] * * paragraphs [0220] , [ 222] , [ 226] , [ 244] - [0247]; claims 10, 11, 14 * * paragraph [0272] *;
 [Y]WO2005113595  (AVIDEX LTD [GB], et al) [Y] 1-9 * abstract * * page 1, lines 20-25 * * page 3, line 1 - page 4, line 24 * * page 11, line 24 - page 14, line 17 * * page 15, lines 14-32 * * page 20, lines 24-31 * * page 22, line 24 - page 23, line 20 *;
 [Y]WO2006037960  (AVIDEX LTD [GB], et al) [Y] 1-9 * abstract * * page 2, line 20 - page 3, line 31 * * page 4, line 7 - page 6, line 18 * * page 7, line 25 - page 8, line 25 * * page 10, line 24 - page 11, line 22 * * page 17, line 1 - page 18, line 9 *;
 [A]  - BIBOLLET-RUCHE FREDERIC ET AL, "The Quality of Chimpanzee T-Cell Activation and Simian Immunodeficiency Virus/Human Immunodeficiency Virus Susceptibility Achieved via Antibody-Mediated T-Cell Receptor/CD3 Stimulation Is a Function of the Anti-CD3 Antibody Isotype", JOURNAL OF VIROLOGY, (200810), vol. 82, no. 20, ISSN 0022-538X, pages 10271 - 10278, XP002600945 [A] 1-9 * abstract * * page 10272, column 1, paragraph 4 *

DOI:   http://dx.doi.org/10.1128/JVI.01319-08
 [A]  - SCHLITT H J ET AL, "DIFFERENT ACTIVATION STATES OF HUMAN LYMPHOCYTES AFTER ANTIBODY-MEDIATED STIMULATION VIA CD3 AND THE ALPHA-BETA T CELL RECEPTOR", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, (1990), vol. 32, no. 6, ISSN 0300-9475, pages 717 - 726, XP002600946 [A] 1-9 * abstract *
 [A]  - LI BOHUA ET AL, "Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions", IMMUNOLOGY, (200512), vol. 116, no. 4, ISSN 0019-2805, pages 487 - 498, XP002600947 [A] 1-9 * abstract *

DOI:   http://dx.doi.org/10.1111/J.1365-2567.2005.02247.X
by applicantWO03020763
    - NEETHLING FA. ET AL., VACCINE, (2008), vol. 26, no. 25, pages 3092 - 102
    - CHAMES P. ET AL., PROC NATL ACAD SCI U S A, (2000), vol. 97, no. 14, pages 7969 - 74
    - WILLEMSEN RA. ET AL., J IMMUNOL, (2005), vol. 174, no. 12, pages 7853 - 8
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OppositionWO0193913
 WO03020763
 WO2004033685
 WO2004074322
 US2004253632
 WO2006037960
 WO2008135734
 US2009042285
    - ORTIZ-SANCHEZ E et al., "Antibody- cytokine fusion proteins: applica- tions in cancer therapy", Expert Opin Biol Ther., (20080000), vol. 8, no. 5, pages 609 - 632, XP008145785

DOI:   http://dx.doi.org/10.1517/14712598.8.5.609
    - MOLLOY PE et al., "Soluble T cell receptors: novel immunotherapies", Curr Opin Phar- macol, (20050800), vol. 5, no. 4, pages 438 - 443, XP004969013

DOI:   http://dx.doi.org/10.1016/j.coph.2005.02.004
    - CARD KF et al., "A soluble single- chain T- cell receptor IL -2 fusion protein retains MHC-restricted peptide specificity and IL -2 bioac- tivity", Cancer Immunol Immu- nother, (20040000), vol. 53, pages 345 - 357, XP002351550

DOI:   http://dx.doi.org/10.1007/s00262-003-0450-3
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    - JONATHAN M. BOULTER et al., "Stable, soluble T- cell receptor molecules for crys- tallization and therapeutics", Pro- tein Engineering, (20030901), vol. 16, no. 9, pages 707 - 711, XP002275339

DOI:   http://dx.doi.org/10.1093/protein/gzg087
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DOI:   http://dx.doi.org/10.1007/s00262-008-0504-7
    - DENKBERG G et al., "Recombinant antibodies with T- cell receptor-like specificity: novel tools to study MHC class I presen- tation", Autoimmun Rev., (20060400), vol. 5, no. 4, pages 252 - 257, XP005428923

DOI:   http://dx.doi.org/10.1016/j.autrev.2005.07.004
    - ARGOS P, "An investigation of oligo- peptides linking domains in protein tertiary structures and possible can- didates for general gene fusion", J Mol Biol., (19900220), vol. 211, no. 4, pages 943 - 958, XP009043079

DOI:   http://dx.doi.org/10.1016/0022-2836(90)90085-Z
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