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Extract from the Register of European Patents

EP About this file: EP3269812

EP3269812 - CELL-FREE ULTRA-HIGH THROUGHPUT SAMPLING SYSTEMS FOR PROTEIN ENGINEERING [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  21.12.2018
Database last updated on 11.09.2024
FormerThe application has been published
Status updated on  15.12.2017
Most recent event   Tooltip21.12.2018Application deemed to be withdrawnpublished on 23.01.2019  [2019/04]
Applicant(s)For all designated states
Rheinisch-Westfälische Technische Hochschule Aachen (RWTH)
Templergraben 55
52062 Aachen / DE
[2018/03]
Inventor(s)01 / Schwaneberg, Ulrich
Worringer Weg 3
52074 Aachen / DE
02 / Vojcic, Ljubica
Worringer Weg 3
52074 Aachen / DE
03 / Körfer, Georgette
Worringer Weg 3
52074 Aachen / DE
04 / Pitzler, Christian
Worringer Weg 3
52074 Aachen / DE
05 / Mertens, Alan
Worringer Weg 3
52074 Aachen / DE
06 / Martinez-Moya, Ronny
Worringer Weg 3
52074 Aachen / DE
 [2018/03]
Representative(s)Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Postfach 10 60 78
28060 Bremen / DE
[2018/03]
Application number, filing date16179234.613.07.2016
[2018/03]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP3269812
Date:17.01.2018
Language:DE
[2018/03]
Search report(s)(Supplementary) European search report - dispatched on:EP01.02.2017
ClassificationIPC:C12N15/10
[2018/03]
CPC:
C12N15/1034 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/03]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:ZELLFREIE ULTRA-HOCHDURCHSATZ-DURCHMUSTERUNGSSYSTEME FÜR DAS PROTEIN-ENGINEERING[2018/03]
English:CELL-FREE ULTRA-HIGH THROUGHPUT SAMPLING SYSTEMS FOR PROTEIN ENGINEERING[2018/03]
French:SYSTEMES DE SELECTION A ULTRA-HAUT DEBIT EXEMPTS DE CELLULE POUR L'INGENIERIE DES PROTEINES[2018/03]
Examination procedure18.07.2018Application deemed to be withdrawn, date of legal effect  [2019/04]
04.09.2018Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2019/04]
Fees paidPenalty fee
Additional fee for renewal fee
31.07.201803   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]  - SYLVIA MAY ET AL, "In Vitro Expressed GPCR Inserted in Polymersome Membranes for Ligand-Binding Studies", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, DE, (20121119), vol. 52, no. 2, doi:10.1002/anie.201204645, ISSN 1433-7851, pages 749 - 753, XP055271230 [X] 12,13 * the whole document * [Y] 1-13

DOI:   http://dx.doi.org/10.1002/anie.201204645
    [ ] - May S, "Functional characterisation of in vitro synthesised G-protein coupled receptors in polymersomes", (20120702), Dissertation, URL: http://ubm.opus.hbz-nrw.de/volltexte/2012/3184/pdf/doc.pdf, (20161213), XP055328492 [ ] * das ganze Dokument, insbesondere "Materials and Methods" und "Results and Discussion) *
 [XY]  - Madhavan Nallani ET AL, "Proteopolymersomes: in vitro production of a membrane protein in polymersome membranes", Biointerphases, United States, doi:10.1116/1.3644384], (20111201), page 153, URL: http://download.springer.com/static/pdf/195/art%3A10.1116%2F1.3644384.pdf?originUrl=http://link.springer.com/article/10.1116/1.3644384&token2=exp=1455205035~acl=/static/pdf/195/art%253A10.1116%252F1.3644384.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1116%2F1.3644384*~hmac=3cc6922ed1, (20160211), XP055249466 [X] 12,13 * das ganze Dokument, insbesondere Fig. 1 * [Y] 1-13

DOI:   http://dx.doi.org/10.1116/1.3644384
 [XY]  - BALASUBRAMANIAN VIMALKUMAR ET AL, "Multifaceted polymersome platforms: Spanning from self-assembly to drug delivery and protocells", PROGRESS IN POLYMER SCIENCE, PERGAMON PRESS, OXFORD, GB, (20160520), vol. 60, doi:10.1016/J.PROGPOLYMSCI.2016.04.004, ISSN 0079-6700, pages 51 - 85, XP029712061 [X] 12,13 * das ganze Dokument, insbesodere "6.3. Gene and protein expressing protocells" * [Y] 1-13

DOI:   http://dx.doi.org/10.1016/j.progpolymsci.2016.04.004
 [Y]  - GEORGETTE KÖRFER ET AL, "In vitro flow cytometry-based screening platform for cellulase engineering", SCIENTIFIC REPORTS, (20160517), vol. 6, doi:10.1038/srep26128, page 26128, XP055327597 [Y] 1-13 * das ganze Dokument, insbesondere Abb. 1 *

DOI:   http://dx.doi.org/10.1038/srep26128
 [Y]  - GEORGETTE WIRTZ ET AL, "Development of a flow cytometer-based in vitro compartmentalization screening platform for directed protein evolution", NEW BIOTECHNOLOGY, NL, (20140701), vol. 31, doi:10.1016/j.nbt.2014.05.1987, ISSN 1871-6784, page S149, XP055327598 [Y] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.nbt.2014.05.1987
 [A]  - MALINOVA V ET AL, "Synthetic biology, inspired by synthetic chemistry", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 586, no. 15, doi:10.1016/J.FEBSLET.2012.05.033, ISSN 0014-5793, (20120516), pages 2146 - 2156, (20120612), XP028400692 [A] 1-13

DOI:   http://dx.doi.org/10.1016/j.febslet.2012.05.033
 [A]  - PASCAL TANNER ET AL, "Polymeric Vesicles: From Drug Carriers to Nanoreactors and Artificial Organelles", ACCOUNTS OF CHEMICAL RESEARCH, (20111018), vol. 44, no. 10, doi:10.1021/ar200036k, ISSN 0001-4842, pages 1039 - 1049, XP055201342 [A] 1-13

DOI:   http://dx.doi.org/10.1021/ar200036k
 [A]  - VALERIE TALY ET AL, "Droplets as Microreactors for High-Throughput Biology", CHEMBIOCHEM - A EUROPEAN JOURNAL OF CHEMICAL BIOLOGY., DE, (20070212), vol. 8, no. 3, doi:10.1002/cbic.200600425, ISSN 1439-4227, pages 263 - 272, XP055327895 [A] 1-13

DOI:   http://dx.doi.org/10.1002/cbic.200600425
 [A]  - CHRISTIAN PITZLER ET AL, "A Fluorescent Hydrogel-Based Flow Cytometry High-Throughput Screening Platform for Hydrolytic Enzymes", CHEMISTRY AND BIOLOGY., GB, (20141201), vol. 21, no. 12, doi:10.1016/j.chembiol.2014.10.018, ISSN 1074-5521, pages 1733 - 1742, XP055327601 [A] 1-13

DOI:   http://dx.doi.org/10.1016/j.chembiol.2014.10.018
by applicant   - TEE, K. L.; SCHWANEBERG, U., COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, (2007), vol. 10, no. 3, page 197
    - LEEMHUIS, H.; KELLY, R. M.; DIJKHUIZEN, L., IUBMB LIFE, (2009), vol. 61, no. 3, page 222
    - BARET, J.-C. ET AL., LAB ON A CHIP, (2009), vol. 9, no. 13, page 1850
    - MASTROBATTISTA, E. ET AL., CHEMISTRY & BIOLOGY, (2005), vol. 12, no. 12, page 1291
    - MILLER, O. J. ET AL., NATURE METHODS, (2006), vol. 3, no. 7, page 561
    - LIEBL, W. ET AL., APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, (2014), vol. 98, no. 19, page 8099
    - BLANUSA, M.; SCHENK, A.; SADEGHI, H.; MARIENHAGEN, J.; SCHWANEBERG, U., ANALYTICAL BIOCHEMISTRY, (2010), vol. 406, no. 2, page 141
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