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Extract from the Register of European Patents

EP About this file: EP3247804

EP3247804 - HIGH MULTIPLEX PCR WITH MOLECULAR BARCODING [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.06.2021
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  03.07.2020
FormerGrant of patent is intended
Status updated on  23.02.2020
FormerExamination is in progress
Status updated on  15.06.2018
FormerRequest for examination was made
Status updated on  27.10.2017
FormerThe international publication has been made
Status updated on  22.08.2017
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024 [2024/41]
Applicant(s)For all designated states
Qiagen Sciences, LLC
19300 Germantown Road
Germantown, MD 20874 / US
[2017/48]
Inventor(s)01 / WANG, Yexun
4442 Cross Country Drive
Ellicott City, Maryland 21042 / US
02 / PENG, Quan
12436 Great Park Circle Apt. 304
Germantown, Maryland 20876 / US
 [2017/48]
Representative(s)Roth, Carla, et al
König-Szynka-Tilmann-von Renesse
Patentanwälte Partnerschaft mbB
Mönchenwerther Straße 11
40545 Düsseldorf / DE
[2017/48]
Application number, filing date16704966.721.01.2016
[2017/48]
WO2016US14274
Priority number, dateUS201562107137P23.01.2015         Original published format: US 201562107137 P
[2017/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016118719
Date:28.07.2016
Language:EN
[2016/30]
Type: A1 Application with search report 
No.:EP3247804
Date:29.11.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 28.07.2016 takes the place of the publication of the European patent application.
[2017/48]
Type: B1 Patent specification 
No.:EP3247804
Date:05.08.2020
Language:EN
[2020/32]
Search report(s)International search report - published on:EP28.07.2016
ClassificationIPC:C12Q1/686, C12Q1/6869
[2020/07]
CPC:
C12Q1/686 (EP,US); C12Q1/6869 (EP,US)
C-Set:
C12Q1/6869, C12Q2535/122, C12Q2563/179 (EP,US);
C12Q1/686, C12Q2525/161, C12Q2535/122, C12Q2537/143, C12Q2563/179 (US,EP)
Former IPC [2017/48]C12Q1/68
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/48]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:HOCHMULTIPLEX-PCR MIT MOLEKULARER STRICHCODIERUNG[2017/48]
English:HIGH MULTIPLEX PCR WITH MOLECULAR BARCODING[2017/48]
French:PCR EN MULTIPLEX ÉLEVÉ À L'AIDE DE MARQUAGE PAR CODE-BARRES MOLÉCULAIRE[2017/48]
Entry into regional phase21.08.2017National basic fee paid 
21.08.2017Designation fee(s) paid 
21.08.2017Examination fee paid 
Examination procedure21.08.2017Examination requested  [2017/48]
21.08.2017Date on which the examining division has become responsible
16.03.2018Amendment by applicant (claims and/or description)
13.06.2018Despatch of a communication from the examining division (Time limit: M06)
02.01.2019Reply to a communication from the examining division
12.04.2019Despatch of a communication from the examining division (Time limit: M06)
22.10.2019Reply to a communication from the examining division
24.02.2020Communication of intention to grant the patent
24.06.2020Fee for grant paid
24.06.2020Fee for publishing/printing paid
24.06.2020Receipt of the translation of the claim(s)
Divisional application(s)EP20189429.2  / EP3763825
Opposition(s)07.05.2021No opposition filed within time limit [2021/28]
Fees paidRenewal fee
26.01.2018Renewal fee patent year 03
22.01.2019Renewal fee patent year 04
23.01.2020Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU21.01.2016
AL05.08.2020
AT05.08.2020
CY05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
MK05.08.2020
MT05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
[2024/41]
Former [2024/22]HU21.01.2016
AL05.08.2020
AT05.08.2020
CY05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
MK05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
Former [2023/30]HU21.01.2016
AL05.08.2020
AT05.08.2020
CY05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
Former [2023/27]HU21.01.2016
AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
Former [2022/34]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
BE31.01.2021
CH31.01.2021
LI31.01.2021
Former [2022/07]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
IE21.01.2021
LU21.01.2021
CH31.01.2021
LI31.01.2021
Former [2021/52]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
LU21.01.2021
CH31.01.2021
LI31.01.2021
Former [2021/43]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
LU21.01.2021
Former [2021/40]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
MC05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/36]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SI05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/28]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SK05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/25]AL05.08.2020
AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/22]AT05.08.2020
CZ05.08.2020
DK05.08.2020
EE05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RO05.08.2020
RS05.08.2020
SE05.08.2020
SM05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/21]AT05.08.2020
DK05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RS05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/12]AT05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
NL05.08.2020
PL05.08.2020
RS05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/10]AT05.08.2020
ES05.08.2020
FI05.08.2020
HR05.08.2020
LT05.08.2020
LV05.08.2020
PL05.08.2020
RS05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
IS05.12.2020
PT07.12.2020
Former [2021/09]AT05.08.2020
ES05.08.2020
FI05.08.2020
LT05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
GR06.11.2020
PT07.12.2020
Former [2021/08]ES05.08.2020
FI05.08.2020
LT05.08.2020
SE05.08.2020
BG05.11.2020
NO05.11.2020
PT07.12.2020
Former [2021/07]FI05.08.2020
LT05.08.2020
NO05.11.2020
Cited inInternational search[XY]US2005170373  (MONFORTE JOSEPH [US]) [X] 32-47 * the whole document * * para. 25, 48-50, 66, 93-95, Fig. 3, 4 * [Y] 1-31;
 [Y]WO2009036525  (UNIV LEUVEN KATH [BE], et al) [Y] 1-47 * the whole document * * p. 6, 7; Fig. 4, 6 *;
 [Y]WO2013130512  (UNIV NORTH CAROLINA [US]) [Y] 1-47 * the whole document * * para. 5, 14, 114, Fig. 1 *;
 [XI]WO2013138510  (PATEL ABHIJIT AJIT [US]) [X] 1-3,5-20,22,24-28,30,31 * the whole document * * p. 21, 25, 28, 66 - p. 71, Fig. 1 * [I] 4,21,23,29,32-47;
 [XY]WO2014145992  (ADAPTIVE BIOTECHNOLOGIES CORP [US]) [X] 32-47 * the whole document * * para. 76-78, Fig. 1, 3 * [Y] 1-31;
 [XY]WO2014171898  (AGENCY SCIENCE TECH & RES [SG]) [X] 32-47 * the whole document * * 34, 47, Fig. 1 * [Y] 1-31;
 [XPI]  - QUAN PENG ET AL, "Reducing amplification artifacts in high multiplex amplicon sequencing by using molecular barcodes", BMC GENOMICS, BIOMED CENTRAL LTD, LONDON, UK, (20150807), vol. 16, no. 1, doi:10.1186/S12864-015-1806-8, ISSN 1471-2164, page 589, XP021224943 [XP] 1-31 * the whole document * [I] 32-47

DOI:   http://dx.doi.org/10.1186/s12864-015-1806-8
ExaminationUS8795961
by applicantUS5641658
 US2009026082
 US2010137143
 US2010197509
 US2010282617
 US2013005613
    - WILLIAMS ET AL., NATURE METHODS, (2006), vol. 3, pages 545 - 50
    - MYLLYKANGAS ET AL., Bioinformatics for High Throughput Sequencing, SPRINGER SCIENCE+BUSINESS MEDIA, LLC, (2012), pages 11 - 25
    - BENTLEY, CURR OPIN GENET DEV, (2006), vol. 16, pages 545 - 52
    - BENTLEY ET AL., NATURE, (2008), vol. 456, pages 53 - 59
    - SMITH ET AL., NUCLEIC ACID RES, (2010), vol. 38, page E142
    - VALOUEV ET AL., GENOME RES, (2008), vol. 18, pages 1051 - 63
    - DRMANAC ET AL., SCIENCE, (2010), vol. 327, pages 78 - 81
    - EID ET AL., SCIENCE, (2009), vol. 323, pages 133 - 8
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.