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Extract from the Register of European Patents

EP About this file: EP3277308

EP3277308 - GLUTAMATE OXALOACETATE TRANSAMINASE 1 (GOT1), PREPARATIONS AND METHODS OF GENERATING SAME AND USES THEREOF [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.01.2021
Database last updated on 16.09.2024
FormerExamination is in progress
Status updated on  14.09.2018
FormerRequest for examination was made
Status updated on  05.01.2018
FormerThe international publication has been made
Status updated on  17.10.2017
Most recent event   Tooltip15.01.2021Application deemed to be withdrawnpublished on 17.02.2021  [2021/07]
Applicant(s)For all designated states
Yeda Research and Development Co., Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
[2018/06]
Inventor(s)01 / MIRELMAN, David
5 Harduf Street
5296000 Ramat-Efal / IL
02 / RABINKOV, Aharon
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
03 / RUBAN, Angela
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
04 / JONA, Ghil
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
05 / HAZUM, Eli
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
06 / BUMELIS, Vladas
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
07 / MAKAUSKAS, Nerijus
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
08 / SUDZIUVIENE, Saule
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
09 / NARMONTAITE, Elena
c/o Yeda Research and Development Co. Ltd.
at the Weizmann Institute of Science
P.O. Box 95
7610002 Rehovot / IL
 [2018/06]
Representative(s)Dennemeyer & Associates S.A.
Postfach 70 04 25
81304 München / DE
[2018/06]
Application number, filing date16717478.831.03.2016
[2018/06]
WO2016IL50346
Priority number, dateUS201562140492P31.03.2015         Original published format: US 201562140492 P
[2018/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016157190
Date:06.10.2016
Language:EN
[2016/40]
Type: A1 Application with search report 
No.:EP3277308
Date:07.02.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 06.10.2016 takes the place of the publication of the European patent application.
[2018/06]
Search report(s)International search report - published on:EP06.10.2016
ClassificationIPC:A61K38/45, C12N9/10, C12N15/62
[2018/06]
CPC:
A61K38/45 (EP,KR,US); C12N9/1096 (EP,KR,US); A61P25/00 (EP);
A61P25/28 (EP); A61P3/00 (EP); A61P35/00 (EP);
A61P43/00 (EP); A61P9/10 (EP); C07K1/165 (KR);
C07K1/18 (KR); C07K1/303 (KR); C07K1/36 (KR);
C12Y206/01001 (EP,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/06]
TitleGerman:GLUTAMATOXALOACETATTRANSAMINASE 1 (GOT1), ZUBEREITUNGEN UND VERFAHREN ZUR ERZEUGUNG UND VERWENDUNGEN DAVON[2018/06]
English:GLUTAMATE OXALOACETATE TRANSAMINASE 1 (GOT1), PREPARATIONS AND METHODS OF GENERATING SAME AND USES THEREOF[2018/06]
French:GLUTAMATE OXALOACÉTATE TRANSAMINASE 1 (GOT1), PRÉPARATIONS, PROCÉDÉS DE GÉNÉRATION DES PRÉPARATIONS ET UTILISATIONS DES PRÉPARATIONS[2018/06]
Entry into regional phase16.10.2017National basic fee paid 
16.10.2017Designation fee(s) paid 
16.10.2017Examination fee paid 
Examination procedure16.10.2017Amendment by applicant (claims and/or description)
16.10.2017Examination requested  [2018/06]
16.10.2017Date on which the examining division has become responsible
17.09.2018Despatch of a communication from the examining division (Time limit: M04)
25.01.2019Reply to a communication from the examining division
25.06.2019Despatch of a communication from the examining division (Time limit: M06)
31.10.2019Reply to a communication from the examining division
30.04.2020Despatch of a communication from the examining division (Time limit: M04)
11.09.2020Application deemed to be withdrawn, date of legal effect  [2021/07]
01.10.2020Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2021/07]
Fees paidRenewal fee
13.03.2018Renewal fee patent year 03
13.03.2019Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.03.202005   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XY]EP1493750  (HOFFMANN LA ROCHE [CH]) [X] 1-5 * claim 23; table 2; sequence 149 * [Y] 19-26;
 [Y]WO2006069610  (METANOMICS GMBH [DE], et al) [Y] 7-18,29,30,33-36 * page 2973; table IIa; sequence 54831 * * paragraph [0282.0.0.0] * * paragraph [0310.0.0.0] *;
 [Y]EP2561889  (YEDA RES & DEV [IL]) [Y] 19-21,25 * claims 1-3 *;
 [X]WO2008083271  (LIFESENSORS INC [US], et al) [X] 6,27,28,31,32 * figures 1,7; claims 1-7,19; sequence 63 * * page 1, lines 14-17 * * page 4, lines 1-2 *;
 [X]WO2012159782  (CT DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS CIC BIOGUNE ASOC [ES], et al) [X] 6,27,28,31,32 * figure 1; claims 1,8,33,34 * * page 14, lines 7-9 *;
 [X]WO2008140582  (UNIV EMORY [US], et al) [X] 6,27,28,31,32 * claims 1-5 * * page 2, lines 1-3 *;
 [XY]  - MARBLESTONE JEFFREY G ET AL, "Comparison of SUMO fusion technology with traditional gene fusion systems: Enhanced expression and solubility with SUMO", PROTEIN SCIENCE, WILEY, US, (20060101), vol. 15, no. 1, doi:10.1110/PS.051812706, ISSN 0961-8368, pages 182 - 189, XP002500201 [X] 6,27 * abstract * [Y] 7-18,29,30,33-36

DOI:   http://dx.doi.org/10.1110/PS.051812706
 [Y]  - DOYLE J M ET AL, "THE AMINO ACID SEQUENCE OF CYTOSOLIC ASPARTATE AMINOTRANSFERASE FROM HUMAN LIVER", BIOCHEMICAL JOURNAL, PORTLAND PRESS LTD, GB, (19900915), vol. 270, no. 3, ISSN 0264-6021, pages 651 - 657, XP008006437 [Y] 8,14,19-26 * abstract *
 [Y]  - ANGELA RUBAN ET AL, "MRS of Brain Metabolite Levels Demonstrates the Ability of Scavenging of Excess Brain Glutamate to Protect against Nerve Agent Induced Seizures", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2012 MDPI AG CHE, (20150202), vol. 16, no. 2, doi:10.3390/ijms16023226, ISSN 1661-6596, pages 3226 - 3236, XP055276612 [Y] 22-24,26 * abstract *

DOI:   http://dx.doi.org/10.3390/ijms16023226
 [A]  - "Human GOT1 Recombinant protein (GST tag)", (2014), URL: http://www.novoprolabs.com/p/human-got1-recombinant-protein-gst-tag-508388.html, (20160530), XP002758238 [A] 7-18,29,30,33-36 * the whole document *
 [A]  - TANAKA-HAYASHI AYUMI ET AL, "Isd-aspartate produced by glutamic-oxaloacetic transaminase-1 like 1 (Got1l1): a putative aspartate racemase?", AMINO ACIDS, SPRINGER VERLAG, AU, vol. 47, no. 1, doi:10.1007/S00726-014-1847-3, ISSN 0939-4451, (20141007), pages 79 - 86, (20141007), XP035418067 [A] 7-18,29,30,33-36 * page 81, column 1, line 49 - page 81, column 2, line 1 *

DOI:   http://dx.doi.org/10.1007/s00726-014-1847-3
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.