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Extract from the Register of European Patents

EP About this file: EP3294745

EP3294745 - NOVEL OXATHIOLANE CARBOXYLIC ACIDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.11.2020
Database last updated on 21.08.2024
FormerThe patent has been granted
Status updated on  05.12.2019
FormerGrant of patent is intended
Status updated on  31.07.2019
FormerRequest for examination was made
Status updated on  18.06.2019
FormerGrant of patent is intended
Status updated on  04.12.2018
FormerRequest for examination was made
Status updated on  16.02.2018
FormerThe international publication has been made
Status updated on  18.11.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2018/12]
Inventor(s)01 / LIU, Haixia
Building No. 5
Lane 720 Cailun Road
Shanghai 201203 / CN
02 / WU, Guolong
Building No. 5
Lane 720 Cailun Road
Shanghai 201203 / CN
03 / YUN, Hongying
Building No. 5
Lane 720 Cailun Road
Shanghai 201203 / CN
 [2018/12]
Representative(s)Bernard, Guillaume
F. Hoffmann-La Roche AG
Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[2018/12]
Application number, filing date16720138.304.05.2016
[2018/12]
WO2016EP59949
Priority number, dateWO2015CN7857808.05.2015         Original published format: PCT/CN2015/078578
[2018/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016180691
Date:17.11.2016
Language:EN
[2016/46]
Type: A1 Application with search report 
No.:EP3294745
Date:21.03.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 17.11.2016 takes the place of the publication of the European patent application.
[2018/12]
Type: B1 Patent specification 
No.:EP3294745
Date:01.01.2020
Language:EN
[2020/01]
Search report(s)International search report - published on:EP17.11.2016
ClassificationIPC:C07D513/04, A61K31/52, A61P31/12
[2018/12]
CPC:
C07D513/04 (EP,CN,US); A61P1/16 (EP); A61P31/12 (EP);
A61P31/20 (EP); A61P43/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/12]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:NEUARTIGE OXATHIOLAN-CARBONSÄUREN UND DERIVATE ZUR BEHANDLUNG UND PROPHYLAXE VON VIRUSINFEKTIONEN[2018/12]
English:NOVEL OXATHIOLANE CARBOXYLIC ACIDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION[2018/12]
French:NOUVEAUX ACIDES CARBOXYLIQUES OXATHIOLANE ET DÉRIVÉS POUR LE TRAITEMENT ET LA PROPHYLAXIE D'UNE INFECTION VIRALE[2018/12]
Entry into regional phase08.12.2017National basic fee paid 
08.12.2017Designation fee(s) paid 
08.12.2017Examination fee paid 
Examination procedure06.10.2017Date on which the examining division has become responsible
08.12.2017Examination requested  [2018/12]
22.06.2018Amendment by applicant (claims and/or description)
05.12.2018Communication of intention to grant the patent
15.04.2019Fee for grant paid
15.04.2019Fee for publishing/printing paid
22.05.2019Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
17.06.2019Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
01.08.2019Communication of intention to grant the patent
25.11.2019Receipt of the translation of the claim(s)
Opposition(s)02.10.2020No opposition filed within time limit [2020/50]
Request for further processing for:17.06.2019Request for further processing filed
17.06.2019Full payment received (date of receipt of payment)
Request granted
28.06.2019Decision despatched
The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
17.06.2019Request for further processing filed
17.06.2019Full payment received (date of receipt of payment)
Request granted
28.06.2019Decision despatched
Fees paidRenewal fee
07.05.2018Renewal fee patent year 03
08.05.2019Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.05.2016
AL01.01.2020
AT01.01.2020
CY01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
MK01.01.2020
MT01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
IE04.05.2020
LU04.05.2020
PT27.05.2020
BE31.05.2020
[2022/31]
Former [2022/30]HU04.05.2016
AL01.01.2020
AT01.01.2020
CY01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
MT01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
IE04.05.2020
LU04.05.2020
PT27.05.2020
BE31.05.2020
Former [2022/27]HU04.05.2016
AT01.01.2020
CY01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
MT01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
TR01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
IE04.05.2020
LU04.05.2020
PT27.05.2020
BE31.05.2020
Former [2021/24]AT01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
IE04.05.2020
LU04.05.2020
PT27.05.2020
BE31.05.2020
Former [2021/20]AT01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
IE04.05.2020
LU04.05.2020
PT27.05.2020
Former [2021/15]AT01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
LU04.05.2020
PT27.05.2020
Former [2021/10]AT01.01.2020
CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
IT01.01.2020
LT01.01.2020
LV01.01.2020
MC01.01.2020
NL01.01.2020
PL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SI01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/50]CZ01.01.2020
DK01.01.2020
EE01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/49]CZ01.01.2020
DK01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SK01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/48]CZ01.01.2020
DK01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RO01.01.2020
RS01.01.2020
SE01.01.2020
SM01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/47]CZ01.01.2020
DK01.01.2020
ES01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RS01.01.2020
SE01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/40]CZ01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RS01.01.2020
SE01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
IS01.05.2020
PT27.05.2020
Former [2020/39]CZ01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RS01.01.2020
SE01.01.2020
BG01.04.2020
NO01.04.2020
GR02.04.2020
PT27.05.2020
Former [2020/38]CZ01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RS01.01.2020
SE01.01.2020
NO01.04.2020
GR02.04.2020
PT27.05.2020
Former [2020/37]CZ01.01.2020
FI01.01.2020
HR01.01.2020
LT01.01.2020
LV01.01.2020
NL01.01.2020
RS01.01.2020
SE01.01.2020
NO01.04.2020
PT27.05.2020
Former [2020/35]CZ01.01.2020
FI01.01.2020
LT01.01.2020
NL01.01.2020
NO01.04.2020
Former [2020/33]NL01.01.2020
Cited inInternational search[A]WO2005016235  (UNIV CALIFORNIA [US], et al) [A] 1-33 * paragraph [0009] - paragraph [0011] * * claims 1, 4-10, 14 *;
 [AP]WO2016055553  (HOFFMANN LA ROCHE [CH], et al) [AP] 1-33 * pages 1-4 * * page 2, line 30 - page 3, line 7 ** claims 1, 14 *
by applicant   - D. J CONNOLLY; L. AJ O'NEILL, CURRENT OPINION IN PHARMACOLOGY, (2012), vol. 12, pages 510 - 518
    - P. A. ROETHLE ET AL., J. MED. CHEM., (2013), vol. 56, pages 7324 - 7333
    - T. ASSELAH ET AL., CLIN LIVER DIS, (2007), vol. 11, pages 839 - 849
    - "Prodrugs and Drug Delivery Systems", RICHARD B. SILVERMAN, The Organic Chemistry of Drug Design and Drug Action, ACADEMIC PRESS, (2004), pages 497 - 558
    - J. AM. CHEM. SOC., (2009), vol. 131, pages 3450 - 3451
    - TSUNEYASU KAISHO; TAKASHI TANAKA, TRENDS IN IMMUNOLOGY, (200807), vol. 29, no. 7, page 329
    - HIROAKI HEMMI ET AL., NATURE IMMUNOLOGY, (2002), vol. 3, pages 196 - 200
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