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Extract from the Register of European Patents

EP About this file: EP3474886

EP3474886 - METHODS FOR TREATING HYPOPHOSPHATASIA IN CHILDREN AND ADOLESCENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.06.2022
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  02.07.2021
FormerGrant of patent is intended
Status updated on  01.02.2021
FormerExamination is in progress
Status updated on  04.12.2019
FormerRequest for examination was made
Status updated on  29.03.2019
FormerThe international publication has been made
Status updated on  06.01.2018
Most recent event   Tooltip27.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 30.10.2024  [2024/44]
Applicant(s)For all designated states
Alexion Pharmaceuticals, Inc.
100 College Street
New Haven, CT 06510 / US
[2019/18]
Inventor(s)01 / FUJITA, Kenji
54 Greenwood Drive
Milburn, NJ 07041 / US
02 / VALLEE, Marc
1845 Main Street
Concord, MA 01742 / US
03 / PHILLIPS, Dawn
1104 Willow Drive
Chapel Hill, NC 27517 / US
 [2019/18]
Representative(s)D Young & Co LLP
3 Noble Street
London EC2V 7BQ / GB
[N/P]
Former [2019/18]D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
Application number, filing date16739617.527.06.2016
[2019/18]
WO2016US39595
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018004517
Date:04.01.2018
Language:EN
[2018/01]
Type: A1 Application with search report 
No.:EP3474886
Date:01.05.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 04.01.2018 takes the place of the publication of the European patent application.
[2019/18]
Type: B1 Patent specification 
No.:EP3474886
Date:04.08.2021
Language:EN
[2021/31]
Search report(s)International search report - published on:EP04.01.2018
ClassificationIPC:A61K38/46, A61P19/00
[2019/18]
CPC:
A61K38/465 (EP,US); A61B5/112 (US); A61K9/0019 (US);
A61P19/00 (EP,US); C12Y301/03001 (EP,US); G01N2800/38 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/18]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON HYPOPHOSPHATASIE BEI KINDERN UND JUGENDLICHEN[2021/09]
English:METHODS FOR TREATING HYPOPHOSPHATASIA IN CHILDREN AND ADOLESCENTS[2019/18]
French:MÉTHODES DE TRAITEMENT DE L'HYPOPHOSPHATASIE CHEZ L'ENFANT ET L'ADOLESCENT[2019/18]
Former [2019/18]VERFAHREN ZUR BEHANDLUNG VON HYPOPHATASIE BEI KINDERN UND JUGENDLICHEN
Entry into regional phase01.01.2019National basic fee paid 
01.01.2019Designation fee(s) paid 
01.01.2019Examination fee paid 
Examination procedure01.01.2019Examination requested  [2019/18]
01.01.2019Date on which the examining division has become responsible
15.08.2019Amendment by applicant (claims and/or description)
09.12.2019Despatch of a communication from the examining division (Time limit: M04)
20.04.2020Reply to a communication from the examining division
11.05.2020Despatch of a communication from the examining division (Time limit: M04)
21.09.2020Reply to a communication from the examining division
02.02.2021Communication of intention to grant the patent
02.06.2021Fee for grant paid
02.06.2021Fee for publishing/printing paid
02.06.2021Receipt of the translation of the claim(s)
Opposition(s)06.05.2022No opposition filed within time limit [2022/28]
Fees paidRenewal fee
31.12.2018Renewal fee patent year 03
27.06.2019Renewal fee patent year 04
29.06.2020Renewal fee patent year 05
28.06.2021Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.06.2016
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
MK04.08.2021
MT04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
[2024/44]
Former [2024/22]HU27.06.2016
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
MK04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2024/20]HU27.06.2016
AL04.08.2021
AT04.08.2021
CY04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2024/18]HU27.06.2016
AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2023/08]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
MC04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/36]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SI04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/29]AL04.08.2021
AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/25]AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
SM04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/24]AT04.08.2021
CZ04.08.2021
DK04.08.2021
EE04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RO04.08.2021
RS04.08.2021
SE04.08.2021
SK04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/21]AT04.08.2021
DK04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/16]AT04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
NL04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/10]AT04.08.2021
FI04.08.2021
HR04.08.2021
LT04.08.2021
LV04.08.2021
PL04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
GR05.11.2021
IS04.12.2021
PT06.12.2021
Former [2022/09]AT04.08.2021
FI04.08.2021
LT04.08.2021
RS04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
PT06.12.2021
Former [2022/08]AT04.08.2021
FI04.08.2021
LT04.08.2021
SE04.08.2021
BG04.11.2021
NO04.11.2021
Former [2022/07]AT04.08.2021
LT04.08.2021
NO04.11.2021
Cited inInternational search[Y]   DAWN PHILLIPS ET AL: "A modified performance-oriented mobility assessment tool for assessing clinically relevant gait impairments and change in children with hypophosphatasia: development and validation", BONE ABSTRACTS, 1 July 2015 (2015-07-01), XP055339488, ISSN: 2052-1219, DOI: 10.1530/boneabs.4.P136

DOI:   http://dx.doi.org/10.1530/boneabs.4.P136
 [XY]   ANONYMOUS: "HIGHLIGHTS OF PRESCRIBING INFORMATION", 1 October 2015 (2015-10-01), XP055339497, Retrieved from the Internet [retrieved on 20170126]
 [XY]   ANONYMOUS: "Gait Assessment in Children with Childhood Hypophosphatasia: Impairments in Muscle Strength and Physical Function", 1 January 2015 (2015-01-01), XP055339649, Retrieved from the Internet [retrieved on 20170127]
 [XY]   ANONYMOUS: "Printing ENDO 2015: Hypophosphatasia in the Spotlight", 1 January 2015 (2015-01-01), XP055339774, Retrieved from the Internet [retrieved on 20170127]
 [XY]   ANONYMOUS: "NCT02235493 on 2015_11_19: ClinicalTrials.gov Archive", 19 November 2015 (2015-11-19), XP055339659, Retrieved from the Internet [retrieved on 20170127]
 [XY]   CARLA EPPS ET AL: "CENTER FOR DRUG EVALUATION AND RESEARCH", 1 January 2015 (2015-01-01), XP055339606, Retrieved from the Internet [retrieved on 20170127]
 [XY]   ANONYMOUS: "Improvement in bone manifestations and respiratory status in infants and young children with HPP treated with asfotase alfa: an update on the ENB-010-10 trial", 1 January 2015 (2015-01-01), XP055339614, Retrieved from the Internet [retrieved on 20170127]
by applicantUS201662305450
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 WO2005103263
 WO2008138131
 US7763712
 US7960529
 US2013323244
 WO2005007809
 US4485045
 US4544545
 US5013556
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.