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Extract from the Register of European Patents

EP About this file: EP3250689

EP3250689 - METHODS AND COMPOSITIONS FOR LABELING A SINGLE-STRANDED TARGET NUCLEIC ACID [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.09.2021
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  02.10.2020
FormerGrant of patent is intended
Status updated on  06.05.2020
FormerRequest for examination was made
Status updated on  03.11.2017
FormerThe international publication has been made
Status updated on  18.07.2017
Most recent event   Tooltip13.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 16.10.2024  [2024/42]
Applicant(s)For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607 / US
[2017/49]
Inventor(s)01 / O'CONNELL, Mitchell R.
731 Stanley Hall
Berkeley, California 94720 / US
02 / DOUDNA, Jennifer A.
708A Stanley Hall
Berkeley, California 94720 / US
 [2017/49]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[2020/45]
Former [2017/49]Green, Katherine, et al
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date16744052.827.01.2016
[2017/49]
WO2016US15178
Priority number, dateUS201562108967P28.01.2015         Original published format: US 201562108967 P
[2017/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016123243
Date:04.08.2016
Language:EN
[2016/31]
Type: A1 Application with search report 
No.:EP3250689
Date:06.12.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 04.08.2016 takes the place of the publication of the European patent application.
[2017/49]
Type: B1 Patent specification 
No.:EP3250689
Date:04.11.2020
Language:EN
[2020/45]
Search report(s)International search report - published on:US04.08.2016
(Supplementary) European search report - dispatched on:EP18.06.2018
ClassificationIPC:C12N15/00, C12N9/14, C12N9/22, C12Q1/68
[2017/49]
CPC:
C12N9/22 (EP); C12Q1/6806 (US); C12N9/222 (US);
C12Q1/6818 (US); C12Q1/701 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/49]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR MARKIERUNG EINER EINZELSTRÄNGIGEN ZIELNUKLEINSÄURE[2017/49]
English:METHODS AND COMPOSITIONS FOR LABELING A SINGLE-STRANDED TARGET NUCLEIC ACID[2017/49]
French:PROCÉDÉS ET COMPOSITIONS POUR LE MARQUAGE D'UN ACIDE NUCLÉIQUE CIBLE MONOCATÉNAIRE[2017/49]
Entry into regional phase27.07.2017National basic fee paid 
27.07.2017Search fee paid 
27.07.2017Designation fee(s) paid 
27.07.2017Examination fee paid 
Examination procedure17.07.2017Date on which the examining division has become responsible
27.07.2017Examination requested  [2017/49]
02.04.2020Amendment by applicant (claims and/or description)
14.05.2020Communication of intention to grant the patent
22.09.2020Fee for grant paid
22.09.2020Fee for publishing/printing paid
22.09.2020Receipt of the translation of the claim(s)
Opposition(s)05.08.2021No opposition filed within time limit [2021/41]
Fees paidRenewal fee
29.01.2018Renewal fee patent year 03
28.01.2019Renewal fee patent year 04
27.01.2020Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.01.2016
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Documents cited:Search[A]   SAMUEL HENRY STERNBERG: "Mechanism and engineering of CRISPR-associated endonucleases", 1 September 2014 (2014-09-01), University of California, Berkeley, pages 1 - 179, XP055481490, Retrieved from the Internet [retrieved on 20180606] [A] 1-21 * Chapter 6 *
 [A]   BERNARD JUSKOWIAK: "Nucleic acid-based fluorescent probes and their analytical potential", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, BERLIN, DE, vol. 399, no. 9, 29 October 2010 (2010-10-29), pages 3157 - 3176, XP019885328, ISSN: 1618-2650, DOI: 10.1007/S00216-010-4304-5 [A] 1-21 * the whole document *

DOI:   http://dx.doi.org/10.1007/s00216-010-4304-5
 [A]   J. A. DOUDNA ET AL: "The new frontier of genome engineering with CRISPR-Cas9", SCIENCE, vol. 346, no. 6213, 28 November 2014 (2014-11-28), pages 1258096 - 1258096, XP055162699, ISSN: 0036-8075, DOI: 10.1126/science.1258096 [A] 1-21 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.1258096
International search[Y] US5846726  (NADEAU JAMES G et al.) [Y] 1-6, 8, 9, 38-41, 43-45 * . Especially col 3 In 41-58, col 8 In 19-21 *
 [Y]   O'CONNELL ET AL.: "Programmable RNA recognition and cleavage by CRISPR/Cas9.", NATURE, vol. 516, no. 7530, pages 263 - 266, XP055168138 [Y] 1-6, 8, 9, 38-41, 43-45 * . Especially abstract, pg 264 fig 3C, pg 265 col 1 para 2. *

DOI:   http://dx.doi.org/10.1038/nature13769
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.