| EP3328355 - IMPLANT COMPOSITIONS FOR THE UNIDIRECTIONAL DELIVERY OF THERAPEUTIC COMPOUNDS TO THE BRAIN [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 08.07.2022 Database last updated on 28.03.2026 | |
| Former | The patent has been granted Status updated on 30.07.2021 | ||
| Former | Grant of patent is intended Status updated on 08.03.2021 | ||
| Former | Examination is in progress Status updated on 11.02.2021 | ||
| Former | Grant of patent is intended Status updated on 28.09.2020 | ||
| Former | Examination is in progress Status updated on 08.05.2019 | ||
| Former | Request for examination was made Status updated on 04.05.2018 | ||
| Former | The international publication has been made Status updated on 03.02.2017 | Most recent event Tooltip | 19.12.2025 | Lapse of the patent in a contracting state New state(s): TR | published on 21.01.2026 [2026/04] | Applicant(s) | For all designated states Board of Regents, The University of Texas System 210 West 7th Street Austin, TX 78701 / US | [2021/11] |
| Former [2018/23] | For all designated states Board of Regents, The University of Texas System 201 West 7th Street Austin, TX 78701 / US | Inventor(s) | 01 /
MCGINITY, Michael J. c/o Ut Health Science Center At San Antonio Dep. of Neurosurgery 7703 Floyd Curl Dr. MC 7843 San Antonio, TX 78229 / US | 02 /
ZHANG, Feng 17133 Bishopsgate Dr. Pflugerville, TX 78660 / US | 03 /
FLOYD, John R. c/o Ut Health Science Center At San Antonio Dept. of Neurosurgery 7703 Floyd Curl Dr. MC 7843 San Antonio, TX 78229 / US | 04 /
MCGINITY, James W. 4209 Dunning Lane Austin, TX 78746 / US | [2021/35] |
| Former [2018/23] | 01 /
MCGINITY, Michael, J. c/o Ut Health Science Center At San Antonio Dep. of Neurosurgery 7703 Floyd Curl Dr. MC 7843 San Antonio, TX 78229 / US | ||
| 02 /
ZHANG, Feng 17133 Bishopsgate Dr. Pflugerville, TX 78660 / US | |||
| 03 /
FLOYD, John, R. c/o Ut Health Science Center At San Antonio Dept. of Neurosurgery 7703 Floyd Curl Dr. MC 7843 San Antonio, TX 78229 / US | |||
| 04 /
MCGINITY, James, W. 4209 Dunning Ln. Austin, TX 78746 / US | Representative(s) | Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München / DE | [2018/23] | Application number, filing date | 16748241.3 | 28.07.2016 | [2018/23] | WO2016US44390 | Priority number, date | US201562198040P | 28.07.2015 Original published format: US 201562198040 P | US201562197739P | 28.07.2015 Original published format: US 201562197739 P | US201662329973P | 29.04.2016 Original published format: US 201662329973 P | [2018/23] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017019829 | Date: | 02.02.2017 | Language: | EN | [2017/05] | Type: | A1 Application with search report | No.: | EP3328355 | Date: | 06.06.2018 | Language: | EN | The application published by WIPO in one of the EPO official languages on 02.02.2017 takes the place of the publication of the European patent application. | [2018/23] | Type: | B1 Patent specification | No.: | EP3328355 | Date: | 01.09.2021 | Language: | EN | [2021/35] | Search report(s) | International search report - published on: | EP | 02.02.2017 | Classification | IPC: | A61K9/00, A61L27/54, A61K31/436, A61K31/155, A61K31/198, A61K31/282, A61K47/10, A61K31/337, A61K47/12, A61K47/14, A61K47/36, A61K31/40, A61K31/4745, A61K31/495, A61K31/519, A61K31/538, A61P35/00 | [2020/40] | CPC: |
A61K9/0085 (EP,US);
A61K31/155 (EP,US);
A61K31/198 (EP,US);
A61K31/282 (EP,US);
A61K31/337 (EP,US);
A61K31/40 (EP,US);
A61K31/436 (EP,US);
A61K31/4745 (EP,US);
A61K31/495 (EP,US);
A61K31/519 (EP,US);
A61K31/538 (EP,US);
A61K31/573 (EP,US);
A61K31/661 (EP,US);
A61K31/704 (EP,US);
A61K33/243 (EP,US);
A61K39/3955 (US);
A61K47/10 (EP,US);
A61K47/12 (EP,US);
A61K47/14 (EP,US);
A61K47/36 (EP,US);
A61K9/0024 (EP,US);
A61K9/7007 (US);
A61L27/54 (EP,US);
A61P35/00 (EP);
A61L2430/32 (EP,US)
(-)
| C-Set: |
A61L27/54, A61L2300/43 (EP,US);
A61L27/54, A61L2300/604 (US,EP) |
| Former IPC [2018/23] | A61K9/00, A61K47/10, A61K31/337, A61P35/00, A61K47/12, A61K47/14, A61K47/36 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/23] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | IMPLANTATZUSAMMENSETZUNGEN ZUR EINSEITIGEN ABGABE VON THERAPEUTISCHEN VERBINDUNGEN AN DAS GEHIRN | [2018/23] | English: | IMPLANT COMPOSITIONS FOR THE UNIDIRECTIONAL DELIVERY OF THERAPEUTIC COMPOUNDS TO THE BRAIN | [2018/23] | French: | COMPOSITIONS D'IMPLANT DESTINÉES À L'APPORT UNIDIRECTIONNEL DE COMPOSÉS THÉRAPEUTIQUES AU CERVEAU | [2018/23] | Entry into regional phase | 28.02.2018 | National basic fee paid | 28.02.2018 | Designation fee(s) paid | 28.02.2018 | Examination fee paid | Examination procedure | 12.02.2018 | Date on which the examining division has become responsible | 28.02.2018 | Examination requested [2018/23] | 19.09.2018 | Amendment by applicant (claims and/or description) | 13.05.2019 | Despatch of a communication from the examining division (Time limit: M06) | 25.11.2019 | Reply to a communication from the examining division | 24.08.2020 | Cancellation of oral proceeding that was planned for 17.09.2020 | 17.09.2020 | Date of oral proceedings (cancelled) | 29.09.2020 | Communication of intention to grant the patent | 09.02.2021 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 09.02.2021 | Fee for grant paid | 09.02.2021 | Fee for publishing/printing paid | 16.03.2021 | Communication of intention to grant the patent | 26.07.2021 | Receipt of the translation of the claim(s) | Opposition(s) | 02.06.2022 | No opposition filed within time limit [2022/32] | Fees paid | Renewal fee | 24.07.2018 | Renewal fee patent year 03 | 30.07.2019 | Renewal fee patent year 04 | 14.07.2020 | Renewal fee patent year 05 | 15.07.2021 | Renewal fee patent year 06 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 28.07.2016 | AL | 01.09.2021 | AT | 01.09.2021 | CY | 01.09.2021 | CZ | 01.09.2021 | DK | 01.09.2021 | EE | 01.09.2021 | ES | 01.09.2021 | FI | 01.09.2021 | HR | 01.09.2021 | IT | 01.09.2021 | LT | 01.09.2021 | LV | 01.09.2021 | MC | 01.09.2021 | MK | 01.09.2021 | MT | 01.09.2021 | NL | 01.09.2021 | PL | 01.09.2021 | RO | 01.09.2021 | RS | 01.09.2021 | SE | 01.09.2021 | SI | 01.09.2021 | SK | 01.09.2021 | SM | 01.09.2021 | TR | 01.09.2021 | BG | 01.12.2021 | NO | 01.12.2021 | GR | 02.12.2021 | IS | 01.01.2022 | PT | 03.01.2022 | [2026/04] |
| Former [2024/42] | HU | 28.07.2016 | |
| AL | 01.09.2021 | ||
| AT | 01.09.2021 | ||
| CY | 01.09.2021 | ||
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| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
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| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2024/22] | HU | 28.07.2016 | |
| AL | 01.09.2021 | ||
| AT | 01.09.2021 | ||
| CY | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
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| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| MC | 01.09.2021 | ||
| MK | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SI | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2024/20] | HU | 28.07.2016 | |
| AL | 01.09.2021 | ||
| AT | 01.09.2021 | ||
| CY | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| MC | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SI | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2024/18] | HU | 28.07.2016 | |
| AL | 01.09.2021 | ||
| AT | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| MC | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SI | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2023/11] | AL | 01.09.2021 | |
| AT | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| MC | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SI | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2022/36] | AL | 01.09.2021 | |
| AT | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| DK | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| IT | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SI | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2022/29] | AL | 01.09.2021 | |
| AT | 01.09.2021 | ||
| CZ | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2022/25] | AT | 01.09.2021 | |
| CZ | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| SM | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2022/24] | AT | 01.09.2021 | |
| CZ | 01.09.2021 | ||
| EE | 01.09.2021 | ||
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| NL | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RO | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| SK | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| IS | 01.01.2022 | ||
| PT | 03.01.2022 | ||
| Former [2022/21] | AT | 01.09.2021 | |
| ES | 01.09.2021 | ||
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| Former [2022/10] | ES | 01.09.2021 | |
| FI | 01.09.2021 | ||
| HR | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| LV | 01.09.2021 | ||
| PL | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| GR | 02.12.2021 | ||
| Former [2022/09] | ES | 01.09.2021 | |
| FI | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| RS | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| Former [2022/08] | ES | 01.09.2021 | |
| FI | 01.09.2021 | ||
| LT | 01.09.2021 | ||
| SE | 01.09.2021 | ||
| BG | 01.12.2021 | ||
| NO | 01.12.2021 | ||
| Former [2022/07] | LT | 01.09.2021 | |
| NO | 01.12.2021 | Cited in | International search | [XI] WO2007112286 (AUXILIUM PHARMACEUTICALS INC et al.) [X] 1-3,11,13-18,20-23,28,29,33,34,37,40-43,46-50,52-54,58,59,61-64,66-77,79 * page 11, line 5; examples 9,12,13 *[I] 4-10,12,19,24-27,30-32,35,36,38,39,44,45,51,55-57,60,65,78,80-91 | [Y] WO2014036290 (UNIV TULANE et al.) [Y] 1-91 * examples 1-6; claims 1-56 * | [Y] KREYE F ET AL: "Drug release mechanisms of cast lipid implants", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 78, no. 3, 15 February 2011 (2011-02-15), pages 394 - 400, XP028241955, ISSN: 0939-6411, [retrieved on 20110223], DOI: 10.1016/J.EJPB.2011.02.011 [Y] 1-91 * the whole document * DOI: http://dx.doi.org/10.1016/j.ejpb.2011.02.011 | Examination | SANDRA HERRMANN ET AL: "New Insight into the Role of Polyethylene Glycol Acting as Protein Release Modifier in Lipidic Implants", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 24, no. 8, 23 March 2007 (2007-03-23), pages 1527 - 1537, XP019507255, ISSN: 1573-904X, DOI: 10.1007/S11095-007-9271-Y DOI: http://dx.doi.org/10.1007/s11095-007-9271-y |