Extract from the Register of European Patents

EP About this file: EP3328355

EP3328355 - IMPLANT COMPOSITIONS FOR THE UNIDIRECTIONAL DELIVERY OF THERAPEUTIC COMPOUNDS TO THE BRAIN [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.07.2022
Database last updated on 28.03.2026
FormerThe patent has been granted
Status updated on  30.07.2021
FormerGrant of patent is intended
Status updated on  08.03.2021
FormerExamination is in progress
Status updated on  11.02.2021
FormerGrant of patent is intended
Status updated on  28.09.2020
FormerExamination is in progress
Status updated on  08.05.2019
FormerRequest for examination was made
Status updated on  04.05.2018
FormerThe international publication has been made
Status updated on  03.02.2017
Most recent event   Tooltip19.12.2025Lapse of the patent in a contracting state
New state(s): TR
published on 21.01.2026  [2026/04]
Applicant(s)For all designated states
Board of Regents, The University of Texas System
210 West 7th Street
Austin, TX 78701 / US
[2021/11]
Former [2018/23]For all designated states
Board of Regents, The University of Texas System
201 West 7th Street
Austin, TX 78701 / US
Inventor(s)01 / MCGINITY, Michael J.
c/o Ut Health Science Center At San Antonio
Dep. of Neurosurgery
7703 Floyd Curl Dr.
MC 7843
San Antonio, TX 78229 / US
02 / ZHANG, Feng
17133 Bishopsgate Dr.
Pflugerville, TX 78660 / US
03 / FLOYD, John R.
c/o Ut Health Science Center At San Antonio
Dept. of Neurosurgery
7703 Floyd Curl Dr.
MC 7843
San Antonio, TX 78229 / US
04 / MCGINITY, James W.
4209 Dunning Lane
Austin, TX 78746 / US
 [2021/35]
Former [2018/23]01 / MCGINITY, Michael, J.
c/o Ut Health Science Center At San Antonio
Dep. of Neurosurgery
7703 Floyd Curl Dr.
MC 7843
San Antonio, TX 78229 / US
02 / ZHANG, Feng
17133 Bishopsgate Dr.
Pflugerville, TX 78660 / US
03 / FLOYD, John, R.
c/o Ut Health Science Center At San Antonio
Dept. of Neurosurgery
7703 Floyd Curl Dr.
MC 7843
San Antonio, TX 78229 / US
04 / MCGINITY, James, W.
4209 Dunning Ln.
Austin, TX 78746 / US
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2018/23]
Application number, filing date16748241.328.07.2016
[2018/23]
WO2016US44390
Priority number, dateUS201562198040P28.07.2015         Original published format: US 201562198040 P
US201562197739P28.07.2015         Original published format: US 201562197739 P
US201662329973P29.04.2016         Original published format: US 201662329973 P
[2018/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017019829
Date:02.02.2017
Language:EN
[2017/05]
Type: A1 Application with search report 
No.:EP3328355
Date:06.06.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 02.02.2017 takes the place of the publication of the European patent application.
[2018/23]
Type: B1 Patent specification 
No.:EP3328355
Date:01.09.2021
Language:EN
[2021/35]
Search report(s)International search report - published on:EP02.02.2017
ClassificationIPC:A61K9/00, A61L27/54, A61K31/436, A61K31/155, A61K31/198, A61K31/282, A61K47/10, A61K31/337, A61K47/12, A61K47/14, A61K47/36, A61K31/40, A61K31/4745, A61K31/495, A61K31/519, A61K31/538, A61P35/00
[2020/40]
CPC:
A61K9/0085 (EP,US); A61K31/155 (EP,US); A61K31/198 (EP,US);
A61K31/282 (EP,US); A61K31/337 (EP,US); A61K31/40 (EP,US);
A61K31/436 (EP,US); A61K31/4745 (EP,US); A61K31/495 (EP,US);
A61K31/519 (EP,US); A61K31/538 (EP,US); A61K31/573 (EP,US);
A61K31/661 (EP,US); A61K31/704 (EP,US); A61K33/243 (EP,US);
A61K39/3955 (US); A61K47/10 (EP,US); A61K47/12 (EP,US);
A61K47/14 (EP,US); A61K47/36 (EP,US); A61K9/0024 (EP,US);
A61K9/7007 (US); A61L27/54 (EP,US); A61P35/00 (EP);
A61L2430/32 (EP,US) (-)
C-Set:
A61L27/54, A61L2300/43 (EP,US);
A61L27/54, A61L2300/604 (US,EP)
Former IPC [2018/23]A61K9/00, A61K47/10, A61K31/337, A61P35/00, A61K47/12, A61K47/14, A61K47/36
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/23]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:IMPLANTATZUSAMMENSETZUNGEN ZUR EINSEITIGEN ABGABE VON THERAPEUTISCHEN VERBINDUNGEN AN DAS GEHIRN[2018/23]
English:IMPLANT COMPOSITIONS FOR THE UNIDIRECTIONAL DELIVERY OF THERAPEUTIC COMPOUNDS TO THE BRAIN[2018/23]
French:COMPOSITIONS D'IMPLANT DESTINÉES À L'APPORT UNIDIRECTIONNEL DE COMPOSÉS THÉRAPEUTIQUES AU CERVEAU[2018/23]
Entry into regional phase28.02.2018National basic fee paid 
28.02.2018Designation fee(s) paid 
28.02.2018Examination fee paid 
Examination procedure12.02.2018Date on which the examining division has become responsible
28.02.2018Examination requested  [2018/23]
19.09.2018Amendment by applicant (claims and/or description)
13.05.2019Despatch of a communication from the examining division (Time limit: M06)
25.11.2019Reply to a communication from the examining division
24.08.2020Cancellation of oral proceeding that was planned for 17.09.2020
17.09.2020Date of oral proceedings (cancelled)
29.09.2020Communication of intention to grant the patent
09.02.2021Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
09.02.2021Fee for grant paid
09.02.2021Fee for publishing/printing paid
16.03.2021Communication of intention to grant the patent
26.07.2021Receipt of the translation of the claim(s)
Opposition(s)02.06.2022No opposition filed within time limit [2022/32]
Fees paidRenewal fee
24.07.2018Renewal fee patent year 03
30.07.2019Renewal fee patent year 04
14.07.2020Renewal fee patent year 05
15.07.2021Renewal fee patent year 06
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Lapses during opposition  TooltipHU28.07.2016
AL01.09.2021
AT01.09.2021
CY01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
MK01.09.2021
MT01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
TR01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
[2026/04]
Former [2024/42]HU28.07.2016
AL01.09.2021
AT01.09.2021
CY01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
MK01.09.2021
MT01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2024/22]HU28.07.2016
AL01.09.2021
AT01.09.2021
CY01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
MK01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2024/20]HU28.07.2016
AL01.09.2021
AT01.09.2021
CY01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2024/18]HU28.07.2016
AL01.09.2021
AT01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2023/11]AL01.09.2021
AT01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
MC01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2022/36]AL01.09.2021
AT01.09.2021
CZ01.09.2021
DK01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
IT01.09.2021
LT01.09.2021
LV01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SI01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2022/29]AL01.09.2021
AT01.09.2021
CZ01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
LT01.09.2021
LV01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2022/25]AT01.09.2021
CZ01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
LT01.09.2021
LV01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SK01.09.2021
SM01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2022/24]AT01.09.2021
CZ01.09.2021
EE01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
LT01.09.2021
LV01.09.2021
NL01.09.2021
PL01.09.2021
RO01.09.2021
RS01.09.2021
SE01.09.2021
SK01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
IS01.01.2022
PT03.01.2022
Former [2022/21]AT01.09.2021
ES01.09.2021
FI01.09.2021
HR01.09.2021
LT01.09.2021
LV01.09.2021
PL01.09.2021
RS01.09.2021
SE01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
Former [2022/10]ES01.09.2021
FI01.09.2021
HR01.09.2021
LT01.09.2021
LV01.09.2021
PL01.09.2021
RS01.09.2021
SE01.09.2021
BG01.12.2021
NO01.12.2021
GR02.12.2021
Former [2022/09]ES01.09.2021
FI01.09.2021
LT01.09.2021
RS01.09.2021
SE01.09.2021
BG01.12.2021
NO01.12.2021
Former [2022/08]ES01.09.2021
FI01.09.2021
LT01.09.2021
SE01.09.2021
BG01.12.2021
NO01.12.2021
Former [2022/07]LT01.09.2021
NO01.12.2021
Cited inInternational search[XI] WO2007112286  (AUXILIUM PHARMACEUTICALS INC et al.) [X] 1-3,11,13-18,20-23,28,29,33,34,37,40-43,46-50,52-54,58,59,61-64,66-77,79 * page 11, line 5; examples 9,12,13 *[I] 4-10,12,19,24-27,30-32,35,36,38,39,44,45,51,55-57,60,65,78,80-91
 [Y] WO2014036290  (UNIV TULANE et al.) [Y] 1-91 * examples 1-6; claims 1-56 *
 [Y]   KREYE F ET AL: "Drug release mechanisms of cast lipid implants", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 78, no. 3, 15 February 2011 (2011-02-15), pages 394 - 400, XP028241955, ISSN: 0939-6411, [retrieved on 20110223], DOI: 10.1016/J.EJPB.2011.02.011 [Y] 1-91 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.ejpb.2011.02.011
Examination  SANDRA HERRMANN ET AL: "New Insight into the Role of Polyethylene Glycol Acting as Protein Release Modifier in Lipidic Implants", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 24, no. 8, 23 March 2007 (2007-03-23), pages 1527 - 1537, XP019507255, ISSN: 1573-904X, DOI: 10.1007/S11095-007-9271-Y

DOI:   http://dx.doi.org/10.1007/s11095-007-9271-y
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