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Extract from the Register of European Patents

EP About this file: EP3256605

EP3256605 - DETECTING MUTATIONS FOR CANCER SCREENING AND FETAL ANALYSIS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.12.2022
Database last updated on 22.08.2024
FormerThe patent has been granted
Status updated on  07.01.2022
FormerGrant of patent is intended
Status updated on  24.10.2021
FormerRequest for examination was made
Status updated on  20.08.2021
FormerGrant of patent is intended
Status updated on  13.05.2021
FormerRequest for examination was made
Status updated on  17.11.2017
FormerThe international publication has been made
Status updated on  05.09.2017
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR
published on 17.07.2024  [2024/29]
Applicant(s)For all designated states
The Chinese University Of Hong Kong
Office of Research and Knowledge Transfer Services
(ORKTS)
Room 301Pi Ch'iu Building
Shatin, New Territories
Hong Kong 999077 / CN
[2017/51]
Inventor(s)01 / LO, Yuk-Ming Dennis
4th Floor
7 King Tak Street
Homantin
Kowloon
Hong Kong 999077 / CN
02 / CHIU, Rossa Wai Kwun
House 31
Double Haven
52 Ma Lok Path
Shatin, New Territories
Hong Kong 999077 / CN
03 / CHAN, Kwan Chee
Flat C 15th Floor Block 5
Peak One
Mei Tin Road
Shatin, New Territories
Hong Kong 999077 / CN
04 / JIANG, Peiyong
Flat 7 on 1st Floor of Block B of Kwong Lam Court
Nos. 62-66 (No.62) Siu Lek Yuen Road
Shatin
New Territories
Hong Kong / CN
 [2017/51]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[2022/06]
Former [2017/51]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date16748745.314.02.2016
[2017/51]
WO2016CN73753
Priority number, dateUS201562114471P10.02.2015         Original published format: US 201562114471 P
US201562271196P22.12.2015         Original published format: US 201562271196 P
[2017/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016127944
Date:18.08.2016
Language:EN
[2016/33]
Type: A1 Application with search report 
No.:EP3256605
Date:20.12.2017
Language:EN
The application published by WIPO in one of the EPO official languages on 18.08.2016 takes the place of the publication of the European patent application.
[2017/51]
Type: B1 Patent specification 
No.:EP3256605
Date:09.02.2022
Language:EN
[2022/06]
Search report(s)International search report - published on:CN18.08.2016
(Supplementary) European search report - dispatched on:EP18.09.2018
ClassificationIPC:G16B20/00, G16B30/00
[2021/20]
CPC:
G16B20/00 (EP,CN,US); G16B20/50 (KR); C12Q1/6806 (EP,CN,KR,US);
C12Q1/6886 (CN,KR,US); G16B20/20 (EP,CN,US); G16B30/00 (EP,CN,KR,US);
G16B30/10 (EP,CN,US); C12Q2600/154 (CN,KR,US); C12Q2600/156 (CN,KR,US) (-)
C-Set:
C12Q1/6806, C12Q2535/122 (CN,EP,US)
Former IPC [2018/42]G06F19/18, G06F19/22
Former IPC [2017/51]C12Q1/68, C40B40/06, C40B40/08
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/51]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:NACHWEIS VON MUTATIONEN FÜR KREBSSCREENING UND FETALE ANALYSE[2017/51]
English:DETECTING MUTATIONS FOR CANCER SCREENING AND FETAL ANALYSIS[2017/51]
French:DÉTECTION DE MUTATIONS UTILISÉES POUR LE DÉPISTAGE DU CANCER ET L'ANALYSE FOETALE[2017/51]
Entry into regional phase05.09.2017National basic fee paid 
05.09.2017Search fee paid 
05.09.2017Designation fee(s) paid 
05.09.2017Examination fee paid 
Examination procedure05.09.2017Examination requested  [2017/51]
05.09.2017Date on which the examining division has become responsible
15.02.2019Amendment by applicant (claims and/or description)
14.05.2021Communication of intention to grant the patent
20.08.2021Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
25.10.2021Communication of intention to grant the patent
21.12.2021Fee for grant paid
21.12.2021Fee for publishing/printing paid
21.12.2021Receipt of the translation of the claim(s)
Divisional application(s)EP21205562.8  / EP4012715
Opposition(s)10.11.2022No opposition filed within time limit [2023/03]
Fees paidRenewal fee
14.02.2018Renewal fee patent year 03
13.02.2019Renewal fee patent year 04
13.02.2020Renewal fee patent year 05
12.02.2021Renewal fee patent year 06
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL09.02.2022
CY09.02.2022
CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
MK09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
TR09.02.2022
BG09.05.2022
IS09.06.2022
[2024/29]
Former [2024/22]AL09.02.2022
CY09.02.2022
CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
MK09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2024/20]AL09.02.2022
CY09.02.2022
CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2023/10]AL09.02.2022
CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2023/01]AL09.02.2022
CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2022/49]CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2022/48]CZ09.02.2022
EE09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2022/47]HR09.02.2022
LT09.02.2022
LV09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SM09.02.2022
BG09.05.2022
IS09.06.2022
Former [2022/42]HR09.02.2022
LT09.02.2022
LV09.02.2022
PL09.02.2022
RS09.02.2022
BG09.05.2022
IS09.06.2022
Former [2022/36]HR09.02.2022
LT09.02.2022
LV09.02.2022
PL09.02.2022
RS09.02.2022
BG09.05.2022
Former [2022/35]HR09.02.2022
LT09.02.2022
RS09.02.2022
BG09.05.2022
Former [2022/33]LT09.02.2022
Documents cited:Search[A]US2014100121  (LO YUK-MING DENNIS [CN], et al) [A] 1-16 * whole doc, in particular claims , [0230] *;
 [AP]US2015087529  (LO YUK-MING DENNIS [CN], et al) [AP] 1-16 * the whole document *;
 [A]  - MARYAM HEIDARY ET AL, "The dynamic range of circulating tumor DNA in metastatic breast cancer", BREAST CANCER RESEARCH, CURRENT MEDICINE GROUP LTD, GB, (20140809), vol. 16, no. 4, doi:10.1186/S13058-014-0421-Y, ISSN 1465-5411, page 421, XP021196558 [A] 1-16 * whole document, in particular abstract, p.3, 4, 7 and fig.4 *

DOI:   http://dx.doi.org/10.1186/s13058-014-0421-y
 [A]  - DAVID L GOODE ET AL, "A simple consensus approach improves somatic mutation prediction accuracy", GENOME MEDICINE,, (20130930), vol. 5, no. 9, doi:10.1186/GM494, ISSN 1756-994X, page 90, XP021165732 [A] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1186/gm494
 [A]  - KRISTIAN CIBULSKIS ET AL, "Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples", NATURE BIOTECHNOLOGY, (20130210), vol. 31, no. 3, doi:10.1038/nbt.2514, ISSN 1087-0156, pages 213 - 219, XP055256219 [A] 1-16 * whole doc, in particula p.4, variant detection *

DOI:   http://dx.doi.org/10.1038/nbt.2514
International search[A]WO2014039556  (GUARDANT HEALTH INC [US], et al) [A] 1-70* see the whole document *;
 [X]WO2014130890  (TOMA BIOSCIENCES INC [US]) [X] 1-70 * see description, paragragh 27 and claim 207 *
by applicant   - CHEN et al., Nat Med, (19960000), vol. 2, pages 1033 - 1035
    - DIEHL et al., Proc Natl Acad Sci USA, (20050000), vol. 102, pages 16368 - 16373
    - FORSHEW et al., Sci Transl Med, (20120000), vol. 4
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.