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Extract from the Register of European Patents

EP About this file: EP3334837

EP3334837 - ASSESSMENT OF NFKB CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.10.2021
Database last updated on 28.03.2026
FormerThe patent has been granted
Status updated on  13.11.2020
FormerGrant of patent is intended
Status updated on  12.07.2020
FormerExamination is in progress
Status updated on  02.03.2019
FormerRequest for examination was made
Status updated on  18.05.2018
FormerThe international publication has been made
Status updated on  25.02.2017
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024  [2024/41]
Applicant(s)For all designated states
Koninklijke Philips N.V.
High Tech Campus 52
5656 AG Eindhoven / NL
[2020/12]
Former [2018/25]For all designated states
Koninklijke Philips N.V.
High Tech Campus 5
5656 AE Eindhoven / NL
Inventor(s)01 / VAN OOIJEN, Hendrik Jan
c/o High Tech Campus 5
5656 AE Eindhoven / NL
 [2018/25]
Representative(s)Philips Intellectual Property & Standards
High Tech Campus 52
5656 AG Eindhoven / NL
[N/P]
Former [2018/25]Coops, Peter
Philips Intellectual Property & Standards
High Tech Campus 5
5656 AE Eindhoven / NL
Application number, filing date16753888.312.08.2016
[2018/25]
WO2016EP69237
Priority number, dateEP2015018102914.08.2015         Original published format: EP 15181029
[2018/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017029215
Date:23.02.2017
Language:EN
[2017/08]
Type: A1 Application with search report 
No.:EP3334837
Date:20.06.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 23.02.2017 takes the place of the publication of the European patent application.
[2018/25]
Type: B1 Patent specification 
No.:EP3334837
Date:16.12.2020
Language:EN
[2020/51]
Search report(s)International search report - published on:EP23.02.2017
ClassificationIPC:C12Q1/6886
[2020/30]
CPC:
G16B25/20 (EP,US); A61K31/336 (EP,US); A61K31/416 (EP,US);
A61K31/4985 (EP,US); A61K31/573 (EP,US); A61K38/05 (EP,US);
C12Q1/6886 (EP,US); G01N33/5758 (US); G16B25/00 (EP,US);
G16B40/00 (EP,US); G16B5/00 (EP,US); G16B5/20 (EP,US);
C12Q2600/158 (EP,US); G01N2800/60 (US) (-)
Former IPC [2018/25]C12Q1/68, G06F19/12, G06F19/24
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/25]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:BEURTEILUNG DER ZELLULÄREN NFKB-SIGNALISIERUNGSPFADAKTIVITÄT MITTELS MATHEMATISCHER MODELLIERUNG DER ZIELGENEXPRESSION[2018/25]
English:ASSESSMENT OF NFKB CELLULAR SIGNALING PATHWAY ACTIVITY USING MATHEMATICAL MODELLING OF TARGET GENE EXPRESSION[2018/25]
French:ÉVALUATION DE L'ACTIVITÉ DE LA VOIE DE SIGNALISATION CELLULAIRE NFKB UTILISANT UNE MODÉLISATION MATHÉMATIQUE DE L'EXPRESSION DU GÈNE CIBLE[2020/30]
Former [2018/25]ÉVALUATION DE L'ACTIVITÉ DE LA VOIE DE SIGNALISATION CELLULAIRE DE NFKB AU MOYEN DE LA MODÉLISATION MATHÉMATIQUE D'UNE EXPRESSION GÉNIQUE CIBLE
Entry into regional phase14.03.2018National basic fee paid 
14.03.2018Designation fee(s) paid 
14.03.2018Examination fee paid 
Examination procedure12.02.2018Amendment by applicant (claims and/or description)
12.02.2018Date on which the examining division has become responsible
14.03.2018Examination requested  [2018/25]
06.03.2019Despatch of a communication from the examining division (Time limit: M04)
04.07.2019Reply to a communication from the examining division
05.11.2019Despatch of a communication from the examining division (Time limit: M04)
24.02.2020Reply to a communication from the examining division
13.07.2020Communication of intention to grant the patent
10.11.2020Fee for grant paid
10.11.2020Fee for publishing/printing paid
10.11.2020Receipt of the translation of the claim(s)
Opposition(s)17.09.2021No opposition filed within time limit [2021/47]
Fees paidRenewal fee
31.08.2018Renewal fee patent year 03
02.09.2019Renewal fee patent year 04
31.08.2020Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU12.08.2016
AL16.12.2020
AT16.12.2020
CY16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
MK16.12.2020
MT16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
TR16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
[2024/41]
Former [2024/29]HU12.08.2016
AL16.12.2020
AT16.12.2020
CY16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
MK16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
TR16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
Former [2024/22]HU12.08.2016
AL16.12.2020
AT16.12.2020
CY16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
MK16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
Former [2023/30]HU12.08.2016
AL16.12.2020
AT16.12.2020
CY16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
Former [2023/29]HU12.08.2016
AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
Former [2022/35]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
IE12.08.2021
LU12.08.2021
Former [2022/24]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
LU12.08.2021
Former [2022/18]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
MC16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
Former [2022/13]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SI16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
Former [2021/48]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
IT16.12.2020
LT16.12.2020
LV16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
Former [2021/45]AL16.12.2020
AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
Former [2021/42]AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
IS16.04.2021
PT16.04.2021
Former [2021/39]AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
PL16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/37]AT16.12.2020
CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/36]CZ16.12.2020
EE16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/35]CZ16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
RO16.12.2020
RS16.12.2020
SE16.12.2020
SK16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/34]CZ16.12.2020
FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
RS16.12.2020
SE16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/33]FI16.12.2020
HR16.12.2020
LT16.12.2020
LV16.12.2020
RS16.12.2020
SE16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
PT16.04.2021
Former [2021/32]FI16.12.2020
HR16.12.2020
LV16.12.2020
RS16.12.2020
SE16.12.2020
SM16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
Former [2021/28]FI16.12.2020
HR16.12.2020
LV16.12.2020
RS16.12.2020
SE16.12.2020
BG16.03.2021
NO16.03.2021
GR17.03.2021
Former [2021/23]FI16.12.2020
LV16.12.2020
RS16.12.2020
SE16.12.2020
BG16.03.2021
NO16.03.2021
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Former [2021/22]FI16.12.2020
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NO16.03.2021
Former [2021/20]FI16.12.2020
Cited inInternational search[YD] EP2549399  (KONINKL PHILIPS ELECTRONICS NV et al.) [YD] 1-12,15 * paragraph [0070]; claims 1-4, 14, 15 *
 [YD] WO2014102668  (KONINKL PHILIPS NV et al.) [YD] 1-12,15 * the whole document *
 [Y] US2004180341  (SEDIVY JOHN M et al.) [Y] 1-12,15 * table 1 *
 [Y]   YUJUN XING ET AL: "Subset of genes targeted by transcription factor NF-[kappa]B in TNF[alpha]-stimulated human HeLa cells", FUNCTIONAL AND INTEGRATIVE GENOMICS, vol. 13, no. 1, 18 December 2012 (2012-12-18), DE, pages 143 - 154, XP055249443, ISSN: 1438-793X, DOI: 10.1007/s10142-012-0305-0 [Y] 1-12,15 * figures 1, 3, 4 *

DOI:   http://dx.doi.org/10.1007/s10142-012-0305-0
 [Y]   F. FEUERHAKE ET AL: "NF B activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes", BLOOD, vol. 106, no. 4, 15 August 2005 (2005-08-15), US, pages 1392 - 1399, XP055249402, ISSN: 0006-4971, DOI: 10.1182/blood-2004-12-4901 [Y] 1-12,15 * table S1 *

DOI:   http://dx.doi.org/10.1182/blood-2004-12-4901
 [Y]   "NFkB target gene sets", 20 April 2005 (2005-04-20), XP055249438, Retrieved from the Internet [retrieved on 20160211]
 [X]   AFFYMETRIX: "GeneChip TM Human Genome Arrays", INTERNET CITATION, 1 January 2004 (2004-01-01), pages 1 - 4, XP002714318, Retrieved from the Internet [retrieved on 20131008] [X] 13,14 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.