Extract from the Register of European Patents

EP Citations: EP3261663

Cited inSearch
Type:Patent literature
Publication No.:EP1801123  [IY]
 (ALTUS PHARMACEUTICALS INC et al.) [I] 1-19 * See e.g. figures 1-6; examples 6, 26, 28, 31, 32, 34 and 37; paragraphs [0177] - [0185] and [0188] *[Y] 1-19
Type:Patent literature
Publication No.:WO2006133486  [Y]
 (MACFARLANE BURNET INST FOR MED et al.) [Y] 1-19 * See e.g. the abstract *
Type:Non-patent literature
Publication information:[IY]   SAPHIRE ERICA OLLMANN ET AL: "Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: An antibody that broadly neutralizes primary isolates of HIV-1", ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY, MUNKSGAARD PUBLISHERS LTD. COPENHAGEN, DK, vol. 57, no. 1, 1 January 2001 (2001-01-01), pages 168 - 171, XP002452899, ISSN: 0907-4449, DOI: 10.1107/S0907444900017376 [I] 1-19 * See e.g. the abstract; section 2.2. "Crystallization" on page 169, right column, second paragraph; page 169, right column, third paragraph * [Y] 1-19
DOI: http://dx.doi.org/10.1107/S0907444900017376
Type:Non-patent literature
Publication information:[IY]   OLLMANN SAPHIRE E ET AL: "Crystal structure of a neutralizing human IgG against HIV-1: A template for vaccine design", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 293, no. 5532, 10 August 2001 (2001-08-10), pages 1155 - 1159, XP002338502, ISSN: 0036-8075, DOI: 10.1126/SCIENCE.1061692 [I] 1-19 * See page 1155, most right column, beginning of second paragraph * [Y] 1-19
DOI: http://dx.doi.org/10.1126/science.1061692
Type:Non-patent literature
Publication information:[IY]   HARRIS LISA J ET AL: "Refined structure of an intact IgG2a monoclonal antibody", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 36, no. 7, 1 January 1997 (1997-01-01), pages 1581 - 1597, XP009506517, ISSN: 0006-2960, DOI: 10.1021/BI962514+ [I] 1-19 * See e.g. page 1582, left column, second paragraph * [Y] 1-19
DOI: http://dx.doi.org/10.1021/bi962514+
Type:Non-patent literature
Publication information:[IY]   HARRIS L J ET AL: "Crystallographic structure of an intact IgG1 monoclonal antibody", JOURNAL OF MOLECULAR BIO, ACADEMIC PRESS, UNITED KINGDOM, vol. 275, no. 5, 6 February 1998 (1998-02-06), pages 861 - 872, XP004461446, ISSN: 0022-2836, DOI: 10.1006/JMBI.1997.1508 [I] 1-19 * See e.g. the abstract; the line bridging left and right columns on page 869 *[Y] 1-19
DOI: http://dx.doi.org/10.1006/jmbi.1997.1508
Type:Non-patent literature
Publication information:[IY]   HARRIS L J ET AL: "CRYSTALLIZATION OF INTACT MONOCLONAL ANTIBODIES", PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS, JOHN WILEY & SONS, INC, US, vol. 23, no. 2, 1 October 1995 (1995-10-01), pages 285 - 289, XP001098112, ISSN: 0887-3585, DOI: 10.1002/PROT.340230218 [I] 1-19 * See e.g. the abstract; page 286, left column, fourth paragraph *[Y] 1-19
DOI: http://dx.doi.org/10.1002/prot.340230218
Type:Non-patent literature
Publication information:[Y]   SHARMA SADHANA ET AL: "Preparation, purification and crystallization of antibody Fabs and single-chain Fv domains", 1 January 1997, IMMUNOLOGY METHODS MANUAL : THE COMPREHENSIVE SOURCEBOOK OF TECHNIQUES, SAN DIEGO [U.A.] : ACAD. PRESS, 1997, US, PAGE(S) 15 - 37, ISBN: 978-0-12-442711-2, XP009506515 [Y] 1-19 * See e.g. pages 32 to 34 for general teachings about crystallization of antibody Fabs and single-chain Fv domains *
Type:Non-patent literature
Publication information:[IY]   HARRIS L J ET AL: "COMPARISON OF THE CONFORMATIONS OF TWO INTACT MONOCLONAL ANTIBODIES WITH HINGES", IMMUNOLOGICAL REVI, WILEY-BLACKWELL PUBLISHING, INC, US, vol. 163, 1 June 1998 (1998-06-01), pages 35 - 43, XP009056421, ISSN: 0105-2896, DOI: 10.1111/J.1600-065X.1998.TB01186.X [I] 1-19 * See e.g. page 35, first paragraph of the introduction *[Y] 1-19
DOI: http://dx.doi.org/10.1111/j.1600-065X.1998.tb01186.x
Type:Non-patent literature
Publication information:[PX]   SCAPIN GIOVANNA ET AL: "Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab", NATURE STRUCTURAL & MOLECULAR BIOLOGY, NATURE PUBLISHING GROUP, US, vol. 22, no. 12, 1 December 2015 (2015-12-01), pages 953 - 958, XP002766296, ISSN: 1545-9985, DOI: 10.1038/NSMB.3129 [PX] 1-19 * The whole document. This is the publication of the invention, co-authored by the inventors *
DOI: http://dx.doi.org/10.1038/nsmb.3129
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Publication No.:WO2008121301  
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Publication information:  ABRAHAMS GABRIEL JAN ET AL: "BLAST ing away preconceptions in crystallization trials", ACTA CRYSTALLOGRAPHICA SECTION F STRUCTURAL BIOLOGY COMMUNICATIONS, vol. 75, no. 3, 4 January 2019 (2019-01-04), pages 184 - 192, XP55792250, DOI: 10.1107/S2053230X19000141 [Y] 1-19
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Publication information:  OMID HAMID ET AL: "Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma", NEW ENGLAND JOURNAL OF MEDICINE, vol. 369, no. 2, 11 July 2013 (2013-07-11), pages 134 - 144, XP055182016, ISSN: 0028-4793, DOI: 10.1056/NEJMoa1305133 [I] 1-19 * See e.g. the abstract; section 2.2. "Crystallization" on page 169, right column, second paragraph; page 169, right column, third paragraph *[Y] 1-19
DOI: http://dx.doi.org/10.1056/NEJMoa1305133
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Cited inother
Type:Patent literature
Publication No.:WO02102303  
Type:Patent literature
Publication No.:US7960516  
Type:Patent literature
Publication No.:WO2008121301  
Type:Non-patent literature
Publication information:  OMID HAMID, CAROLINE ROBERT, ADIL DAUD, F. STEPHEN HODI, WEN-JEN HWU, RICHARD KEFFORD, JEDD D. WOLCHOK, PETER HERSEY, RICHARD W. J: "Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma", NEW ENGLAND JOURNAL OF MEDICINE, NEW ENGLAND JOURNAL OF MEDICINE, vol. 369, no. 2, 11 July 2013 (2013-07-11), pages 134 - 144, XP055182016, ISSN: 00284793, DOI: 10.1056/NEJMoa1305133
DOI: http://dx.doi.org/10.1056/NEJMoa1305133