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Extract from the Register of European Patents

EP About this file: EP3271383

EP3271383 - STAPLED PEPTIDES AND USES THEREOF [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  17.02.2023
Database last updated on 24.08.2024
FormerThe application is deemed to be withdrawn
Status updated on  07.01.2022
FormerExamination is in progress
Status updated on  18.03.2020
FormerRequest for examination was made
Status updated on  28.12.2017
FormerThe international publication has been made
Status updated on  27.10.2017
Most recent event   Tooltip26.03.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
London Health Sciences Centre Research Inc.
Suite 105
100 Collip Circle
London, ON N6G 4X8 / CA
[2018/04]
Inventor(s)01 / LUYT, Leonard
129 High Street
London, Ontario N6C 4K3 / CA
02 / TURLEY, Eva
1-517 Dufferin Avenue
London, Ontario N6B 2A3 / CA
03 / HAUSER-KAWAGUCHI, Alexandra
27 Olsen Drive
Toronto, Ontario M3A 3J1 / CA
04 / RODRIGUES, Emily
11 Billington Crescent
Hamilton, Ontario L8T 4P9 / CA
 [2018/04]
Representative(s)Lengyel, Zsolt
POB 198
1368 Budapest / HU
[2018/04]
Application number, filing date16767835.821.03.2016
[2018/04]
WO2016IB51587
Priority number, dateUS201562135951P20.03.2015         Original published format: US 201562135951 P
[2018/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016151478
Date:29.09.2016
Language:EN
[2016/39]
Type: A1 Application with search report 
No.:EP3271383
Date:24.01.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 29.09.2016 takes the place of the publication of the European patent application.
[2018/04]
Search report(s)International search report - published on:CA29.09.2016
(Supplementary) European search report - dispatched on:EP10.05.2019
ClassificationIPC:C07K14/47, C07K14/705, A61K38/17, A61K49/00, A61K51/08, A61K9/127, A61P17/02, A61P35/00, A61P35/04, C07K7/08, C07K7/64, G01N33/53, G01N33/574
[2019/09]
CPC:
C07K7/64 (EP,US); A61K38/014 (EP,US); A61K38/08 (US);
A61K38/10 (US); A61K38/177 (EP,US); A61P17/02 (EP);
A61P35/00 (EP); A61P35/04 (EP); C07K14/47 (EP,US);
C07K14/705 (EP,US); C07K7/06 (EP,US); C07K7/08 (EP,US);
G01N33/53 (EP,US); A61K38/00 (EP,US); A61K47/36 (EP,US);
G01N2800/7052 (EP,US); G01N2800/7095 (EP,US); G01N33/564 (EP,US);
G01N33/574 (EP,US) (-)
C-Set:
A61K38/014, A61K2300/00 (EP,US)
Former IPC [2018/04]C07K14/705, A61K38/17, A61K47/48, A61K49/00, A61K51/08, A61K9/127, A61P17/02, A61P35/00, A61P35/04, C07K7/06, C07K7/08, C07K7/50, C07K7/64, G01N33/53, G01N33/574
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/04]
TitleGerman:GEHEFTETE PEPTIDE UND VERWENDUNGEN DAVON[2018/04]
English:STAPLED PEPTIDES AND USES THEREOF[2018/04]
French:PEPTIDES AGRAFÉS ET LEURS UTILISATIONS[2018/04]
Entry into regional phase20.10.2017National basic fee paid 
20.10.2017Search fee paid 
20.10.2017Designation fee(s) paid 
20.10.2017Examination fee paid 
Examination procedure20.10.2017Examination requested  [2018/04]
20.10.2017Date on which the examining division has become responsible
09.12.2019Amendment by applicant (claims and/or description)
23.03.2020Despatch of a communication from the examining division (Time limit: M06)
30.09.2020Reply to a communication from the examining division
11.03.2021Despatch of a communication from the examining division (Time limit: M06)
22.09.2021Application deemed to be withdrawn, date of legal effect  [2022/06]
15.12.2021Reply to a communication from the examining division
deletedDeletion: Application deemed to be withdrawn, date of legal effect  [2023/12]
17.07.2023Despatch of a communication from the examining division (Time limit: M04)
16.02.2024Reply to a communication from the examining division
Divisional application(s)EP21198177.4   Application deemed to be withdrawn  : 22.09.2021
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
16.02.2024Request for further processing filed
16.02.2024Full payment received (date of receipt of payment)
Request granted
26.02.2024Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
15.12.2021Request for further processing filed
15.12.2021Full payment received (date of receipt of payment)
Request granted
10.10.2022Decision despatched
Request for re-establishment of rights:07.01.2022Date of receipt
Fees paidRenewal fee
22.02.2018Renewal fee patent year 03
06.03.2019Renewal fee patent year 04
06.03.2020Renewal fee patent year 05
19.01.2021Renewal fee patent year 06
31.03.2022Renewal fee patent year 07
09.02.2023Renewal fee patent year 08
25.03.2024Renewal fee patent year 09
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Documents cited:Search[A]WO03033535  (TRANSITION THERAPEUTICS INC [CA], et al) [A] 1-15 * pages 3,5,27; claims 1-3,8-10; sequences 81,82 *;
 [A]WO2014082042  (UNIV CALIFORNIA [US]) [A] 1-15 * paragraphs [0028] , [0029] , [0085] , [0109] , [0121] , [0122]; figure 1; claims 1,33,60; sequence 2 *;
 [A]  - LOREN D. WALENSKY ET AL, "Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress : Miniperspective", JOURNAL OF MEDICINAL CHEMISTRY, (20140306), vol. 57, no. 15, doi:10.1021/jm4011675, ISSN 0022-2623, pages 6275 - 6288, XP055537971 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm4011675
 [A]  - LUKASZ FRANKIEWICZ ET AL, "Stabilisation of a short [alpha] -helical VIP fragment by side chain to side chain cyclisation: a comparison of common cyclisation motifs by circular dichroism", JOURNAL OF PEPTIDE SCIENCE, (20130727), vol. 19, no. 7, doi:10.1002/psc.2515, ISSN 1075-2617, pages 423 - 432, XP055139042 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/psc.2515
 [T]  - Emily Rodrigues, "Design and Synthesis of Hyaluronan: RHAMM Interaction Inhibitors", Electronic Thesis and Dissertation Repository of the University of Western Ontario, (20170901), URL: https://ir.lib.uwo.ca/etd/4876, (20190102), XP055537946 [T] * the whole document *
International search[A]CA2160603  (UNIV MANITOBA [CA], et al) [A] 0 *Abstract; Fig. 18A *;
 [A]CA2237051  (TURLEY EVA A [CA]) [A] 0 *Abstract; p. 16, third paragraph *;
 [Y]WO2006130974  (CANGENE CORP [CA], et al) [Y] 1-7, 9-27, 29, 31-48, 55, 62-91, 106 *Table on p. 25, compounds HABP 33 and HABP35; p. 15, second paragraph *;
 [A]WO2011150495  (LONDON HEALTH SCIENCES CT RES INC [CA], et al) [A] 0 *SEQ ID NO:19 (Fig. 1A) *;
 [A]  - YANG et al., "Identification of common hyaluronan binding motif in the hyaluronan binding proteins RHAMM, CD 44 and link protein.", The EMBO Journal, (19940000), vol. 13, no. 2, pages 286 - 296, XP002134781 [A] 0 *Abstract; p. 288, Fig. lA; p. 289, Fig. 2B; p. 291, Table I *
 [A]  - ZIEBELL et al., "Interactions of peptide mimics of hyaluronic acid with the receptor for hyaluronan mediated motility (RHAMM).", Journal of Computer-aided Molecular Design, (20040000), vol. 18, pages 597 - 614, XP019248094 [A] 0 *p. 599, left hand column; p. 609, Fig. 9 *
 [Y]  - SHEPHERD et al., "Single Turn Peptide Alpha Helices with Exceptional Stability in Water.", Journal of the American Chemical Society, (20050000), vol. 127, pages 2974 - 2983, XP008085097 [Y] 1-7, 9-27, 29, 31-48, 55, 62-91, 106 *Introduction; p. 2976, left hand column *

DOI:   http://dx.doi.org/10.1021/ja0456003
 [Y]  - HOUSTON et al., "Lactam bridge stabilization of alpha-helical peptides: ring size, orientation and positional effects.", Journal of Peptide Science, vol. 1, no. 4, pages 274 - 282, XP055315955 [Y] 1-7, 9-27, 29, 31-48, 55, 62-91, 106 *Abstract *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.