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Extract from the Register of European Patents

EP About this file: EP3280272

EP3280272 - EXTRACTS FROM PLANTS OF THE MORINGACEAE FAMILY AND METHODS OF MAKING [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.04.2022
Database last updated on 10.07.2024
FormerThe patent has been granted
Status updated on  23.04.2021
FormerGrant of patent is intended
Status updated on  08.12.2020
FormerExamination is in progress
Status updated on  24.09.2019
FormerRequest for examination was made
Status updated on  12.01.2018
FormerThe international publication has been made
Status updated on  24.10.2017
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR
published on 17.07.2024 [2024/29]
Applicant(s)For all designated states
Rutgers, The State University of New Jersey
Old Queens Building Somerset and George Streets
New Brunswick, NJ 08903 / US
[2018/07]
Inventor(s)01 / RASKIN, Ilya
48 Alexandria Drive
Manalapan, NJ 07726 / US
02 / WATERMAN, Carrie
280 Robbins Beach Road
Killeen, Alabama 35645 / US
 [2018/35]
Former [2018/07]01 / RASKIN, Ilya
48 Alexandria Drive
Manalapan, NJ 07726 / US
02 / WATERMAN, Carrie
35 Tunison Road
New Brunswick, NJ 08901 / US
Representative(s)Lahrtz, Fritz, et al
Simmons & Simmons LLP
Lehel Carré Thierschplatz 6
80538 München / DE
[N/P]
Former [2021/21]Lahrtz, Fritz, et al
Patentanwälte
Isenbruck Bösl Hörschler PartG mbB
Seckenheimer Landstr. 4
68163 Mannheim / DE
Former [2018/07]Lahrtz, Fritz
Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68
81675 München / DE
Application number, filing date16777063.530.03.2016
[2018/07]
WO2016US24924
Priority number, dateUS20151468373010.04.2015         Original published format: US201514683730
[2018/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016164224
Date:13.10.2016
Language:EN
[2016/41]
Type: A1 Application with search report 
No.:EP3280272
Date:14.02.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 13.10.2016 takes the place of the publication of the European patent application.
[2018/07]
Type: B1 Patent specification 
No.:EP3280272
Date:26.05.2021
Language:EN
[2021/21]
Search report(s)International search report - published on:US13.10.2016
(Supplementary) European search report - dispatched on:EP19.11.2018
ClassificationIPC:A23L11/00, A61K8/97, A61K36/185, A61Q19/00, A61P3/00, A61P3/04, A61P3/10, A61K8/66
[2018/51]
CPC:
A61K36/185 (EP,US); A23K20/10 (US); A23L2/52 (EP);
A23L33/105 (EP); A61K31/26 (EP); A61K31/7034 (US);
A61K8/66 (EP); A61K8/9783 (EP,US); A61K8/9789 (EP,US);
A61P3/00 (EP); A61P3/04 (EP); A61P3/10 (EP);
A61Q19/00 (EP,US); A61Q19/06 (EP); A61Q90/00 (EP);
A23K10/30 (EP); A23V2002/00 (EP,US); A61K2236/00 (EP);
A61K2236/15 (EP,US); A61K2236/17 (EP,US); A61K2236/19 (EP,US);
A61K2236/33 (EP,US); A61K2236/331 (EP,US); A61K2236/53 (EP,US);
A61K2800/10 (EP); A61K2800/92 (EP) (-)
C-Set:
A23V2002/00, A23V2200/324, A23V2200/328, A23V2200/332, A23V2250/21 (EP)
Former IPC [2018/07]A23L11/00, A61K8/97, A61K36/185, A61Q19/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/07]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:PFLANZENEXTRAKTE AUS DER FAMILIE MORINGACEAE UND VERFAHREN ZUR HERSTELLUNG[2018/07]
English:EXTRACTS FROM PLANTS OF THE MORINGACEAE FAMILY AND METHODS OF MAKING[2018/07]
French:EXTRAITS DE PLANTES DE LA FAMILLE DES MORINGACÉES ET PROCÉDÉS DE PRODUCTION[2018/07]
Entry into regional phase24.10.2017National basic fee paid 
24.10.2017Search fee paid 
24.10.2017Designation fee(s) paid 
24.10.2017Examination fee paid 
Examination procedure24.10.2017Examination requested  [2018/07]
24.10.2017Date on which the examining division has become responsible
13.06.2019Amendment by applicant (claims and/or description)
27.09.2019Despatch of a communication from the examining division (Time limit: M04)
28.01.2020Reply to a communication from the examining division
03.11.2020Cancellation of oral proceeding that was planned for 10.11.2020
10.11.2020Date of oral proceedings (cancelled)
09.12.2020Communication of intention to grant the patent
15.04.2021Fee for grant paid
15.04.2021Fee for publishing/printing paid
15.04.2021Receipt of the translation of the claim(s)
Opposition(s)01.03.2022No opposition filed within time limit [2022/18]
Fees paidRenewal fee
13.03.2018Renewal fee patent year 03
13.03.2019Renewal fee patent year 04
12.03.2020Renewal fee patent year 05
12.03.2021Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.03.2016
AL26.05.2021
AT26.05.2021
CY26.05.2021
CZ26.05.2021
DK26.05.2021
EE26.05.2021
ES26.05.2021
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HR26.05.2021
IT26.05.2021
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MC26.05.2021
MK26.05.2021
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TR26.05.2021
BG26.08.2021
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GR27.08.2021
IS26.09.2021
PT27.09.2021
[2024/29]
Former [2024/22]HU30.03.2016
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DK26.05.2021
EE26.05.2021
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BG26.08.2021
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Former [2024/18]HU30.03.2016
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DK26.05.2021
EE26.05.2021
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SM26.05.2021
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BG26.08.2021
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GR27.08.2021
IS26.09.2021
PT27.09.2021
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DK26.05.2021
EE26.05.2021
ES26.05.2021
FI26.05.2021
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GR27.08.2021
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EE26.05.2021
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PT27.09.2021
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HR26.05.2021
LT26.05.2021
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GR27.08.2021
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PT27.09.2021
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GR27.08.2021
PT27.09.2021
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Documents cited:Search[T]  - ASHA JAJA-CHIMEDZA ET AL, "Biochemical characterization and anti-inflammatory properties of an isothiocyanate-enriched moringa (Moringa oleifera) seed extract", PLOS ONE, (20170808), vol. 12, no. 8, doi:10.1371/journal.pone.0182658, page e0182658, XP055508153 [T] 1-15 * the whole document * * page 4, paragraph 2 - page 5, paragraph 2 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0182658
 [T]  - YOUJIN KIM ET AL, "A 14-day repeated-dose oral toxicological evaluation of an isothiocyanate-enriched hydro-alcoholic extract from Moringa oleifera Lam. seeds in rats", TOXICOLOGY REPORTS, (20180101), vol. 5, doi:10.1016/j.toxrep.2018.02.012, ISSN 2214-7500, pages 418 - 426, XP055508158 [T] 1-15 * the whole document * * 2.1 Plant material, extraction, and MIC-1 quantification; page 419 *

DOI:   http://dx.doi.org/10.1016/j.toxrep.2018.02.012
 [XY]  - DEHSHAHRI S ET AL, "Determination of volatile glucosinolate degradation products in seed coat, stem and in vitro cultures of Moringa peregrina (Forssk.) Fiori", RESEARCH IN PHARMACEUTICAL SCIENCES, MEDKNOW PUBLICATIONS AND MEDIA PVT. LTD, INDIA, (20120131), vol. 7, no. 1, ISSN 1735-5362, pages 51 - 56, XP009508058 [X] 1,3-7,9,11,12 * the whole document * * Autolysis and collection of the volatile constituents; page 2 * * page 2, paragraph l - page 3, paragraph 1 * [Y] 1-15
 [XY]  - EILERT E ET AL, "THE ANTIBIOTIC PRINCIPLE OF SEEDS OF MORINGA OLEIFERA AND MORINGA STENOEPTALA", PLANTA MEDICA, THIEME VERLAG, DE, (19810101), vol. 42, no. 1, ISSN 0032-0943, pages 55 - 61, XP009024217 [X] 1-7,9-12 * the whole document * * page 57, column l, paragraph 2 * * page 60, column r, paragraph 1 - page 61, column l, paragraph l * [Y] 1-15
 [Y]  - SHAILAJA G. MAHAJAN ET AL, "Inhibitory Action of Ethanolic Extract of Seeds of Moringa oleifera Lam. On Systemic and Local Anaphylaxis", JOURNAL OF IMMUNOTOXICOLOGY, US, (20070101), vol. 4, no. 4, doi:10.1080/15476910701680137, ISSN 1547-691X, pages 287 - 294, XP055508197 [Y] 1-15 * the whole document * * page 288, column r, paragraph 2 *

DOI:   http://dx.doi.org/10.1080/15476910701680137
 [YP]  - CARRIE WATERMAN ET AL, "Isothiocyanate-rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice", MOLECULAR NUTRITION & FOOD RESEARCH, DE, (20150427), vol. 59, no. 6, doi:10.1002/mnfr.201400679, ISSN 1613-4125, pages 1013 - 1024, XP055386467 [YP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/mnfr.201400679
International search[A]US2006127996  (FAHEY JED W [US]) [A] 1-28* , whole document *;
 [Y]US2007264366  (CHEN HUEIH M [TW], et al) [Y] 1-28 * para [0008]; para [0005]; para [0012] *;
 [Y]US2011245526  (EKANAYAKE ATHULA [US], et al) [Y] 1-28 * claim 1; claim 2; para [0030]; para [0057]; para [0087]; para [0057]; para [0031]; claim 17; para [0033]; para [0086] claim 15; para [0070]; para [0044]; para [0041] *;
 [Y]WO2014053944  (UNIV WITWATERSRAND JHB [ZA]) [Y] 21-23 * Abstract; claim 1; page 8, para 1 *;
 [Y]  - WATERMAN et al., "Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro", Phytochemistry, (20140700), vol. 103, pages 114 - 122, XP055321973 [Y] 2, 10, 16 * , especially, page 4, para 4; page 5, para 1; page 4, para 2; Abstract . *

DOI:   http://dx.doi.org/10.1016/j.phytochem.2014.03.028
 [Y]  - BAIS et al., "Antiobesity and Hypolipidemic activity of Moringa oleifera leaves against high fat diet-induced obesity in rats", Advances in Biology., (20140710), vol. 2014, pages 1 - 9, XP055321974 [Y] 24-28 * , especially, Abstract; page 7, Col. 1, para 2; page 7, Col. 1 para 4; page 7, Col. 2, para 1 *

DOI:   http://dx.doi.org/10.1155/2014/162914
by applicantUS5744161
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    - WATERMAN CCHENG DMROJAS-SILVA PPOULEV ADREIFUS JLILA MA et al., "Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro", Phytochem, (20140000), vol. 103, doi:10.1016/j.phytochem.2014.03.028, pages 114 - 22, XP055321973

DOI:   http://dx.doi.org/10.1016/j.phytochem.2014.03.028
    - CHEENPRACHA SPARK E-JYOSHIDA WYBARIT CWALL MPEZZUTO JM et al., "Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits", Bioorgan Med Chem, (20100000), vol. 18, no. 17, pages 6598 - 602, XP027218846
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DOI:   http://dx.doi.org/10.1002/mnfr.200800245
    - BRUNELLI DTAVECCHIO MFALCIONI CFRAPOLLI RERBA EIORI R et al., "The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo", Biochem Pharmacol, (20100000), vol. 79, no. 8, pages 1141 - 8
    - FAIZI SSIDDIQUI BSSALEEM RSIDDIQUI SAFTAB KGILANI AH, "Isolation and structure elucidation of new nitrile and mustard oil glycosides from Moringa oleifera and their effect on blood pressure", J Nat Prod, (19940000), vol. 57, no. 9, doi:10.1021/np50111a011, pages 1256 - 61, XP009024216

DOI:   http://dx.doi.org/10.1021/np50111a011
    - SHAPIRO TAFAHEY JWWADE KLSTEPHENSON KKTALALAY P, "Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts metabolism and excretion in humans", Cancer Epidem Biomar, (20010000), vol. 10, no. 5, pages 501 - 8
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DOI:   http://dx.doi.org/10.1016/j.phrs.2007.01.009
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    - TRAKA MMITHEN R, "Glucosinolates, isothiocyanates and human health", Phytochem Rev, (20090000), vol. 8, no. 1, pages 269 - 82, XP019686429
    - MIRMIRAN PBAHADORAN ZHOSSEINPANAH FKEYZAD AAZIZI F, "Effects of broccoli sprout with high sulforaphane concentration on inflammatory markers in type 2 diabetic patients: A randomized double-blind placebo-controlled clinical trial", J Funct Foods, (20120000), vol. 4, no. 4, doi:10.1016/j.jff.2012.05.012, pages 837 - 41, XP055100429

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