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Extract from the Register of European Patents

EP About this file: EP3297610

EP3297610 - CRYSTALS AS HOSTS FOR ENTRAPMENT AND SLOW RELEASE OF COMPOUNDS [Right-click to bookmark this link]
StatusGrant of patent is intended
Status updated on  08.09.2024
Database last updated on 25.09.2024
FormerExamination is in progress
Status updated on  26.05.2022
FormerRequest for examination was made
Status updated on  23.02.2018
FormerThe international publication has been made
Status updated on  25.11.2016
Most recent event   Tooltip08.09.2024New entry: Communication of intention to grant a patent 
Applicant(s)For all designated states
Technion Research & Development Foundation Ltd.
Senate House
Technion City
3200004 Haifa / IL
[2018/13]
Inventor(s)01 / POKROY, Boaz
Aba Hushi Av. 10a.
3478610 Haifa / IL
02 / CALVARESI, Matteo
via Cesare Beccaria 17
63082 Castel di Lama (AP) / IT
03 / FALINI, Giuseppe
via Masia 3/2
Italy Bologna / IT
04 / POLISHCHUK, Iryna
Yigal Alon 38 apt.8
3298338 Haifa / IL
 [2018/13]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[N/P]
Former [2018/13]Boult Wade Tennant
Verulam Gardens
70 Gray's Inn Road
London WC1X 8BT / GB
Application number, filing date16796025.119.05.2016
[2018/13]
WO2016IL50533
Priority number, dateUS201562164667P21.05.2015         Original published format: US 201562164667 P
[2018/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2016185480
Date:24.11.2016
Language:EN
[2016/47]
Type: A1 Application with search report 
No.:EP3297610
Date:28.03.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 24.11.2016 takes the place of the publication of the European patent application.
[2018/13]
Search report(s)International search report - published on:IL24.11.2016
(Supplementary) European search report - dispatched on:EP15.10.2019
ClassificationIPC:A61K9/18, A61K31/704, A61K38/28, A61K31/713, A61K33/10, A61K45/06, A61P29/00, A61P3/08, A61P31/00, A61P35/00
[2024/33]
CPC:
A61K38/28 (EP,US); A61K47/6949 (US); A61K31/704 (EP,US);
A61K31/713 (EP,US); A61K33/10 (EP,US); A61K45/06 (EP,US);
A61K47/6911 (US); A61K9/0019 (US); A61P29/00 (EP,US);
A61P3/08 (EP,US); A61P31/00 (EP,US); A61P35/00 (EP,US) (-)
C-Set:
A61K31/704, A61K2300/00 (US,EP);
A61K31/713, A61K2300/00 (US,EP);
A61K33/10, A61K2300/00 (EP,US)
Former IPC [2018/13]A61K9/18, A61K31/704, A61K38/28
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/13]
TitleGerman:KRISTALLE ALS WIRTE FÜR DEN EINSCHLUSS UND DIE LANGSAME FREISETZUNG VON VERBINDUNGEN[2018/13]
English:CRYSTALS AS HOSTS FOR ENTRAPMENT AND SLOW RELEASE OF COMPOUNDS[2018/13]
French:CRISTAUX UTILISÉS EN TANT QU'HÔTES POUR LE PIÉGEAGE ET LA LIBÉRATION PROLONGÉE DE COMPOSÉS[2018/13]
Entry into regional phase19.12.2017National basic fee paid 
19.12.2017Search fee paid 
19.12.2017Designation fee(s) paid 
19.12.2017Examination fee paid 
Examination procedure19.12.2017Examination requested  [2018/13]
19.12.2017Date on which the examining division has become responsible
09.01.2019Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time
12.05.2020Amendment by applicant (claims and/or description)
25.05.2022Despatch of a communication from the examining division (Time limit: M06)
02.12.2022Reply to a communication from the examining division
09.09.2024Communication of intention to grant the patent
Fees paidRenewal fee
30.11.2018Renewal fee patent year 03
29.05.2019Renewal fee patent year 04
22.05.2020Renewal fee patent year 05
30.07.2021Renewal fee patent year 06
25.05.2022Renewal fee patent year 07
26.05.2023Renewal fee patent year 08
27.05.2024Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.05.201803   M06   Fee paid on   30.11.2018
31.05.202106   M06   Fee paid on   30.07.2021
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Documents cited:Search[X]CN101428009  (SHANGHAI INST PHARM INDUSTRY [CN]);
 [E]WO2017077539  (ARIEL-UNIVERSITY RES AND DEV COMPANY LTD [IL]);
International search[XY]  - UKRAINCZYK, M. et al., "Interactions of salicylic acid derivatives with calcite crystals.", Journal of colloid and interface science, vol. 365, no. 1, (20110912), pages 296 - 307, URL: http://www.sciencedirect.com/science/article/pii/S0021979711011222, XP028323036 [X] 1-5, 6, 7, 9-19 * ) Figures 7 and 8 and sections 3.3 and 3.4 of the paper. Figures 7 and 8 and sections 3.3 and 3.4 of the paper. Figures 7 and 8 and sections 3.3 and 3.4 of the paper. * [Y] 6-8, 21-25, 38

DOI:   http://dx.doi.org/10.1016/j.jcis.2011.09.009
 [XY]  - POKROY, B. et al., "Anisotropic lattice distortions in biogenic calcite induced by intra-crystalline organic molecules.", Journal of structural biology, vol. 155, no. 1, (20060420), pages 96 - 103, URL: http://www.sciencedirect.com/science/article/pii/51047847706000840, XP024905195 [X] 1-5, 20, 34-37, 39, 6,7, 9-19, 26-33 * ) section 2.7;last paragraphs of section 3 section 2.7;last paragraphs of section 3 section 2.7;last paragraphs of section 3 * [Y] 6-8, 38

DOI:   http://dx.doi.org/10.1016/j.jsb.2006.03.008
 [XY]  - BORUKHIN, S. et al., "Screening the incorporation of amino acids into an inorganic crystalline host: The case of calcite.", Advanced Functional Materials, vol. 22, no. 20, (20120620), pages 4216 - 4224, URL: http://onlinelibrary.wiley.com/doi/10.1002/adfm.201201079/full, XP055330954 [X] 1-5, 6, 7, 9-19, 26-33, 20, 34-37, 39 * ) experimental section; figure 1. experimental section; figure 1. experimental section; figure 1. * [Y] 6-8, 38

DOI:   http://dx.doi.org/10.1002/adfm.201201079
 [Y]  - PENG, C. et al., "Sustained delivery of doxorubicin by porous CaCO 3 and chitosan/alginate multilayers-coated CaCO 3 microparticles.", Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 353, no. 2, (20091110), pages 132 - 139, URL: http://www.sciencedirect.com/science/article/pii/S0927775709006542, XP026806481 [Y] 6-8, 21-25, 38 * ) section 3.3, starting at page 137 and figure 8 *
 [Y]  - PENG, H. et al., "Preparation of hierarchical mesoporous CaCO 3 by a facile binary solvent approach as anticancer drug carrier for etoposide.", Nanoscale research letters, vol. 8, no. 1, (20130715), page 1., URL: https://nanoscalereslett.springeropen.com/articles/10.1186/1556-276X-8-321, XP055330958 [Y] 6-8, 21-25 * ) Figure 7;figure 6 *

DOI:   http://dx.doi.org/10.1186/1556-276X-8-321
 [Y]  - SUKHORUKOV, G. B. et al., "Porous calcium carbonate microparticles as templates for encapsulation of bioactive compounds.", Journal of Materials Chemistry, vol. 14, no. 14, (20040615), pages 2073 - 2081, URL: http://pubs.rsc.org/en/content/articlelanding/2004/jm/b402617a#!divAbstract, XP002352569 [Y] 6, 7 * ) Figure 6 *

DOI:   http://dx.doi.org/10.1039/b402617a
 [Y]  - Wei Wei et al, "Preparation of hierarchical hollow CaC03 particles and the application as anticancer drug carrier.", Journal of the American Chemical Society, vol. 130, no. 47, (20081104), pages 15808 - 15810, URL: http://pubs.acs.org/doi/abs/10.1021/ja8039585, XP055330959 [Y] 6, 7, 21-25, 38 * ) figures 4 and 5 *

DOI:   http://dx.doi.org/10.1021/ja8039585
 [Y]  - KONG, X. et al., "Calcium carbonate microparticles used as a gene vector for delivering p53 gene into cancer cells.", Journal of biomedical materials research Part A, vol. 100, no. 9, (20120424), pages 2312 - 2318, URL: http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.34155/full, XP055330960 [Y] 6, 7, 21-25 * ) Page 2313, paragraph bridging the two columns;page 2313, paragraph bridging the two columns *

DOI:   http://dx.doi.org/10.1002/jbm.a.34155
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