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Extract from the Register of European Patents

EP About this file: EP3377510

EP3377510 - GALNAC CLUSTER PHOSPHORAMIDITE [Right-click to bookmark this link]
Former [2018/39]	GalNAc CLUSTER PHOSPHORAMIDITE
	[2020/25]
Status	No opposition filed within time limit Status updated on 08.10.2021 Database last updated on 31.08.2024
Former	The patent has been granted Status updated on 30.10.2020
Former	Grant of patent is intended Status updated on 29.06.2020
Former	Request for examination was made Status updated on 24.08.2018
Former	The international publication has been made Status updated on 26.05.2017
Former	unknown Status updated on 28.11.2016
Most recent event Tooltip	27.04.2024	Lapse of the patent in a contracting state New state(s): MK	published on 29.05.2024 [2024/22]
Applicant(s)	For all designated states F. Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH
	[2018/39]
Inventor(s)	01 / TRUSSARDI, René c/o F. Hoffmann-La Roche AG Grenzacherstrasse 124 4070 Basel / CH
	[2018/39]
Representative(s)	Rauber, Beat F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124 4070 Basel / CH
	[2018/39]
Application number, filing date	16797831.1	14.11.2016
	[2018/39]
	WO2016EP77516
Priority number, date	EP20150194811	16.11.2015 Original published format: EP 15194811
	[2018/39]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2017084987
	Date:	26.05.2017
	Language:	EN
	[2017/21]
	Type:	A1 Application with search report
	No.:	EP3377510
	Date:	26.09.2018
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 26.05.2017 takes the place of the publication of the European patent application.
	[2018/39]
	Type:	B1 Patent specification
	No.:	EP3377510
	Date:	02.12.2020
	Language:	EN
	[2020/49]
Search report(s)	International search report - published on:	EP	26.05.2017
Classification	IPC:	C07H15/08, C07H21/04	[2018/39]
	CPC:	C07H15/08 (EP,IL,KR,US); C07H1/00 (EP,IL,KR,US); C07H21/04 (EP,IL,KR,US); Y02P20/55 (EP,KR,US)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/39]
Extension states	BA	Not yet paid
	ME	Not yet paid
Validation states	MA	Not yet paid
	MD	Not yet paid
Title	German:	GALNAC CLUSTER PHOSPHORAMIDIT DERIVATE	[2020/25]
	English:	GALNAC CLUSTER PHOSPHORAMIDITE	[2020/25]
	French:	DÉRIVÉ PHOSPHORAMIDITE DU CLUSTER GALNAC	[2020/25]
	Former [2018/39]	GALNAC-CLUSTERPHOSPHORAMIDIT
	Former [2018/39]	GalNAc CLUSTER PHOSPHORAMIDITE
	Former [2018/39]	AGRÉGAT DE GALNAC-PHOSPHORAMIDITE
Entry into regional phase	18.06.2018	National basic fee paid
	18.06.2018	Designation fee(s) paid
	18.06.2018	Examination fee paid
Examination procedure	16.04.2018	Date on which the examining division has become responsible
	18.06.2018	Examination requested [2018/39]
	10.12.2018	Amendment by applicant (claims and/or description)
	30.06.2020	Communication of intention to grant the patent
	13.10.2020	Fee for grant paid
	13.10.2020	Fee for publishing/printing paid
	13.10.2020	Receipt of the translation of the claim(s)
Opposition(s)	03.09.2021	No opposition filed within time limit [2021/45]
Fees paid	Renewal fee
	08.11.2018	Renewal fee patent year 03
	14.11.2019	Renewal fee patent year 04
	23.10.2020	Renewal fee patent year 05
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	14.11.2016
	AL	02.12.2020
	CY	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	MC	02.12.2020
	MK	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
	[2024/22]
Former [2023/30]	HU	14.11.2016
	AL	02.12.2020
	CY	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	MC	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2023/29]	HU	14.11.2016
	AL	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	MC	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2022/33]	AL	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	MC	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2022/23]	AL	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2022/10]	AL	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	PT	05.04.2021
Former [2021/49]	AL	02.12.2020
	CZ	02.12.2020
	DK	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SI	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2021/45]	AL	02.12.2020
	CZ	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2021/42]	CZ	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	IS	02.04.2021
	PT	05.04.2021
Former [2021/36]	CZ	02.12.2020
	EE	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	PT	05.04.2021
Former [2021/35]	CZ	02.12.2020
	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SK	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	PT	05.04.2021
Former [2021/33]	FI	02.12.2020
	HR	02.12.2020
	LT	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
	PT	05.04.2021
Former [2021/32]	FI	02.12.2020
	HR	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	SM	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
Former [2021/28]	FI	02.12.2020
	HR	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
Former [2021/23]	FI	02.12.2020
	LV	02.12.2020
	RS	02.12.2020
	BG	02.03.2021
	NO	02.03.2021
Former [2021/22]	FI	02.12.2020
	RS	02.12.2020
	NO	02.03.2021
Former [2021/20]	FI	02.12.2020
Cited in	International search	[AD]WO2012083046 (ARROWHEAD RES CORP [US], et al) [AD] 1-18 * Claims and examples, in particular Figure 6 *;
		[A]WO2014179620 (ISIS PHARMACEUTICALS INC [US]) [A] 1-18* whole document, in particular claims 1, 32, 63, 94 and 205 and the examples *;
		[A] - PRAKASH THAZHA P ET AL, "Solid-phase synthesis of 5'-triantennaryN-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemi", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (20150808), vol. 25, no. 19, doi:10.1016/J.BMCL.2015.08.019, ISSN 0960-894X, pages 4127 - 4130, XP029264267 [A] 1-18 * Whole document, in particular Scheme 1 and Fifure 1 * DOI: http://dx.doi.org/10.1016/j.bmcl.2015.08.019

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