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Extract from the Register of European Patents

EP About this file: EP3322448

EP3322448 - A NOVEL APPROACH FOR TREATMENT OF CANCER USING IMMUNOMODULATION [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  14.02.2020
Database last updated on 16.09.2024
FormerRequest for examination was made
Status updated on  20.04.2018
FormerThe international publication has been made
Status updated on  20.01.2017
Most recent event   Tooltip12.06.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
OnkosXcel Therapeutics, LLC
555 Long Wharf Drive, 12th Floor
New Haven, CT 06511 / US
[2023/13]
Former [2018/21]For all designated states
Bioxcel Therapeutics, Inc.
780 East Main Street
Branford, CT 06405 / US
Inventor(s)01 / MEHTA, Vimal D.
47 Leighton Trail
Guilford, Connecticut 06437 / US
02 / RASTELLI, Luca
11 Laurelwood Drive
Norwell, Massachusetts 02061 / US
03 / SAPRA, Aparna Katoch
19 Taxila
IIT Delhi
New Delhi 110016 / IN
 [2018/21]
Representative(s)Cooley (UK) LLP
22 Bishopsgate
London EC2N 4BQ / GB
[N/P]
Former [2018/21]Cooley (UK) LLP
Dashwood
69 Old Broad Street
London EC2M 1QS / GB
Application number, filing date16825310.218.07.2016
[2018/21]
WO2016US42798
Priority number, dateUS201562193348P16.07.2015         Original published format: US 201562193348 P
US201562204495P13.08.2015         Original published format: US 201562204495 P
[2018/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017011831
Date:19.01.2017
Language:EN
[2017/03]
Type: A1 Application with search report 
No.:EP3322448
Date:23.05.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 19.01.2017 takes the place of the publication of the European patent application.
[2018/21]
Search report(s)International search report - published on:US19.01.2017
(Supplementary) European search report - dispatched on:EP05.02.2019
ClassificationIPC:A61K45/08, A61K38/04, C07K16/24, C12N15/11
[2018/21]
CPC:
A61K31/69 (EP,CN,KR,RU,US); A61K31/198 (RU); A61K39/3955 (CN,KR,US);
A61K31/40 (RU); A61K38/04 (EP,KR,US); A61K39/395 (RU);
A61K39/39541 (EP,KR,US); A61K45/06 (EP,CN,US); A61P35/00 (EP,CN,KR,RU);
A61P35/02 (EP); A61P35/04 (CN); A61P37/04 (EP,RU);
A61P43/00 (EP); C07K16/2818 (EP,KR,US); C12N15/1137 (EP,KR,US);
A61K2039/505 (EP,KR,US); A61K2039/545 (EP,KR,US); C07K2317/21 (KR,US);
C07K2317/76 (EP,KR,US); C12N2310/14 (EP,US); C12N2320/31 (EP,US) (-)
C-Set:
A61K31/69, A61K2300/00 (US,CN,EP);
A61K39/39541, A61K2300/00 (EP,US);
A61K39/3955, A61K2300/00 (CN)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/21]
Extension statesBA16.02.2018
ME16.02.2018
Validation statesMA16.02.2018
TitleGerman:NEUARTIGES VERFAHREN ZUR BEHANDLUNG VON KREBS MIT IMMUNMODULATION[2018/21]
English:A NOVEL APPROACH FOR TREATMENT OF CANCER USING IMMUNOMODULATION[2018/21]
French:NOUVELLE APPROCHE POUR LE TRAITEMENT DU CANCER PAR IMMUNOMODULATION[2018/21]
Entry into regional phase16.02.2018National basic fee paid 
16.02.2018Search fee paid 
16.02.2018Designation fee(s) paid 
16.02.2018Examination fee paid 
Examination procedure15.02.2017Request for preliminary examination filed
International Preliminary Examining Authority: US
16.02.2018Examination requested  [2018/21]
16.02.2018Date on which the examining division has become responsible
03.09.2019Amendment by applicant (claims and/or description)
18.02.2020Despatch of a communication from the examining division (Time limit: M06)
27.08.2020Reply to a communication from the examining division
23.04.2021Despatch of a communication from the examining division (Time limit: M04)
01.09.2021Reply to a communication from the examining division
Fees paidRenewal fee
31.07.2018Renewal fee patent year 03
25.07.2019Renewal fee patent year 04
14.07.2020Renewal fee patent year 05
15.07.2021Renewal fee patent year 06
16.06.2022Renewal fee patent year 07
14.06.2023Renewal fee patent year 08
12.06.2024Renewal fee patent year 09
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Documents cited:Search[Y]WO2008066729  (POINT THERAPEUTICS INC [US], et al) [Y] 7-16 * the whole document *;
 [XY]US2015125447  (HEIDER KARL-HEINZ [AU]) [X] 1-6 * paragraph [0085] * * paragraph [0087] *[Y] 7-16
International search[XY]US2014271725  (BACHOVCHIN WILLIAM W [US]) [X] 1, 2, 5, 7, 9, 11 * ; abstract; paragraphs [0067], [0070], [0145], [0147], [0148], [0150], [0154]), * [Y] 6, 28, 29;
 [XY]WO2014144600  (ROSCHKE VIKTOR [US], et al) [X] 8, 21, 22 * ; paragraphs [0017], [0019], [0277], [0331], [0336], [0632], [0636], * [Y] 6, 30;
 [Y]US2014335048  (STOGNIEW MARTIN [US], et al) [Y] 30* ; paragraph [0031] *;
 [Y]  - JANSEN, KOEN et al., "Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4- Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold", ACS Medicinal Chemistry Letters, (20130318), vol. 4, pages 491 - 496, XP055186472 [Y] 28, 29 * , second column, second paragraph; page 2, first column, first paragraph *

DOI:   http://dx.doi.org/10.1021/ml300410d
 [Y]  - WALSH, MEGHAAN et al., "Val-BoroPro Accelerates T Cell Priming via Modulation of Dendritic Cell Trafficking Resulting in Complete Regression of Established Murine Tumors", PLOS One, (20130300), vol. 8, no. Issue 3, pages 1 - 13, XP055344567 [Y] 1, 4, 10, 23 * , e58860; abstract; page 9, fist column, second paragraph, figure 9 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0058860
 [Y]  - FEIG, CHRISTINE et al., "Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer", PNAS, (20130000), vol. 110, no. 50, pages 20212 - 20217, XP002760317 [Y] 1, 4, 10, 23 * ; abstract; page 20212, second column, first paragraph, figure 3D, E *

DOI:   http://dx.doi.org/10.1073/pnas.1320318110
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