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Extract from the Register of European Patents

EP About this file: EP3243073

EP3243073 - METHOD FOR CONTROLLING CONTINUOUS CHROMATOGRAPHY AND MULTI-COLUMN CHROMATOGRAPHY ASSEMBLY [Right-click to bookmark this link]
Former [2017/46]METHOD FOR CONTROLLING CONTINUOUS CHROMATOGRAPHY AND MULTI-COLUMN CHROMATOGRAPHY ARRANGEMENT
[2018/16]
StatusThe patent has been granted
Status updated on  08.02.2019
Database last updated on 25.09.2024
FormerGrant of patent is intended
Status updated on  16.11.2018
FormerRequest for examination was made
Status updated on  17.09.2018
FormerGrant of patent is intended
Status updated on  06.05.2018
FormerRequest for examination was made
Status updated on  13.10.2017
FormerThe international publication has been made
Status updated on  02.06.2017
Formerunknown
Status updated on  20.01.2017
Most recent event   Tooltip01.03.2024Change: Date of oral proceedings 
01.03.2024Deletion: Despatch of minutes of oral proceedings 
Applicant(s)For all designated states
Karlsruher Institut für Technologie
Kaiserstrasse 12
76131 Karlsruhe / DE
[2017/46]
Inventor(s)01 / HUBBUCH, Jürgen
Bruckner Straße 7b
76327 Pfinztal / DE
02 / BRESTRICH, Nina
Horburgstrasse 114
4057 Basel / CH
03 / RÜDT, Matthias
Welfenstr. 14a
76137 Karlsruhe / DE
04 / ROLINGER, Laura
Zur Kopp 27
66706 Perl / DE
 [2019/11]
Former [2017/46]01 / HUBBUCH, Jürgen
Bruckner Straße 7b
76327 Pfinztal / DE
02 / BRESTRICH, Nina
Henriette-Obermüller-Strasse 15
76137 Karlsruhe / DE
03 / RÜDT, Matthias
Kriegststrasse 187
76135 Karlsruhe / DE
04 / ROLINGER, Laura
Zur Kopp 27
66706 Perl / DE
Representative(s)Müller-Boré & Partner Patentanwälte PartG mbB
Friedenheimer Brücke 21
80639 München / DE
[2017/46]
Application number, filing date16825323.525.11.2016
[2017/46]
WO2016EP01995
Priority number, dateEP2015019659926.11.2015         Original published format: EP 15196599
[2017/46]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2017088979
Date:01.06.2017
Language:DE
[2017/22]
Type: A1 Application with search report 
No.:EP3243073
Date:15.11.2017
Language:DE
The application published by WIPO in one of the EPO official languages on 01.06.2017 takes the place of the publication of the European patent application.
[2017/46]
Type: B1 Patent specification 
No.:EP3243073
Date:13.03.2019
Language:DE
[2019/11]
Search report(s)International search report - published on:EP01.06.2017
ClassificationIPC:G01N30/86, G01N30/88, G01N30/46
[2017/46]
CPC:
B01D15/1871 (EP,US); B01D15/1814 (EP,US); G01N30/46 (EP,US);
G01N30/74 (US); G01N30/78 (EP,US); G01N30/86 (EP,US);
G01N30/8658 (US); G01N30/8675 (US); G01N2030/8831 (EP,US);
G01N2201/129 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2017/46]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN ZUR STEUERUNG KONTINUIERLICHER CHROMATOGRAPHIE UND MULTISÄULEN-CHROMATOGRAPHIE-ANORDNUNG[2017/46]
English:METHOD FOR CONTROLLING CONTINUOUS CHROMATOGRAPHY AND MULTI-COLUMN CHROMATOGRAPHY ASSEMBLY[2018/16]
French:PROCEDE DE COMMANDE DE CHROMATOGRAPHIE EN CONTINU ET AGENCEMENT DE CHROMATOGRAPHIE MULTICOLONNE[2018/16]
Former [2017/46]METHOD FOR CONTROLLING CONTINUOUS CHROMATOGRAPHY AND MULTI-COLUMN CHROMATOGRAPHY ARRANGEMENT
Former [2017/46]PROCÉDÉ POUR CONTRÔLER UNE CHROMATOGRAPHIE CONTINUE ET ENSEMBLE DE CHROMATOGRAPHIE MULTI-COLONNES
Entry into regional phase09.08.2017National basic fee paid 
09.08.2017Designation fee(s) paid 
09.08.2017Examination fee paid 
Examination procedure09.08.2017Amendment by applicant (claims and/or description)
09.08.2017Examination requested  [2017/46]
09.08.2017Date on which the examining division has become responsible
07.05.2018Communication of intention to grant the patent
12.09.2018Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
13.09.2018Fee for grant paid
13.09.2018Fee for publishing/printing paid
16.11.2018Information about intention to grant a patent
16.11.2018Receipt of the translation of the claim(s)
Opposition(s)Opponent(s)01  09.10.2019  11.10.2019  WITHDRAWN
Bayer AG / Bayer Intellectual Property GmbH
Kaiser-Wilhelm-Allee 1 /
Alfred-Nobel-Straße 10
51373 Leverkusen / 40789 Monheim / DE
Opponent's representative
BIP Patents
c/o Bayer Intellectual Property GmbH
Alfred-Nobel-Straße 50
40789 Monheim am Rhein / DE
 02  13.12.2019  17.12.2019  ADMISSIBLE
Aechter, Bernd
Nymphenburgerstrasse 4
80335 München / DE
Opponent's representative
Ter Meer Steinmeister & Partner
Patentanwälte mbB
Nymphenburger Straße 4
80335 München / DE
 [2023/15]
Former [2020/04]
Opponent(s)01  09.10.2019  11.10.2019  ADMISSIBLE
Bayer AG / Bayer Intellectual Property GmbH
Kaiser-Wilhelm-Allee 1 /
Alfred-Nobel-Straße 10
51373 Leverkusen / 40789 Monheim / DE
Opponent's representative
BIP Patents
c/o Bayer Intellectual Property GmbH
Alfred-Nobel-Straße 10
40789 Monheim am Rhein / DE
 02  13.12.2019  17.12.2019  ADMISSIBLE
Aechter, Bernd
Nymphenburgerstrasse 4
80335 München / DE
Opponent's representative
Ter Meer Steinmeister & Partner
Patentanwälte mbB
Nymphenburger Straße 4
80335 München / DE
Former [2019/46]
Opponent(s)01  09.10.2019    ADMISSIBLE
Bayer AG / Bayer Intellectual Property GmbH
Kaiser-Wilhelm-Allee 1 /
Alfred-Nobel-Straße 10
51373 Leverkusen / 40789 Monheim / DE
Opponent's representative
BIP Patents
c/o Bayer Intellectual Property GmbH
Alfred-Nobel-Straße 10
40789 Monheim am Rhein / DE
07.01.2020Invitation to proprietor to file observations on the notice of opposition
02.06.2020Reply of patent proprietor to notice(s) of opposition
02.12.2021Date of oral proceedings
13.01.2022Despatch of interlocutory decision in opposition
13.01.2022Despatch of minutes of oral proceedings
Appeal following opposition23.03.2022Appeal received No.  T0758/22
23.03.2022Payment of appeal fee
23.05.2022Statement of grounds filed
27.11.2024Date of oral proceedings
Fees paidRenewal fee
30.01.2019Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.11.201803   M06   Fee paid on   30.01.2019
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.11.2016
AL13.03.2019
CY13.03.2019
CZ13.03.2019
DK13.03.2019
EE13.03.2019
ES13.03.2019
FI13.03.2019
HR13.03.2019
IT13.03.2019
LT13.03.2019
LV13.03.2019
MC13.03.2019
MK13.03.2019
MT13.03.2019
NL13.03.2019
PL13.03.2019
RO13.03.2019
RS13.03.2019
SE13.03.2019
SI13.03.2019
SK13.03.2019
SM13.03.2019
TR13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
IS13.07.2019
PT13.07.2019
IE25.11.2019
LU25.11.2019
BE30.11.2019
AT25.11.2021
[2023/07]
Former [2022/32]HU25.11.2016
AL13.03.2019
CY13.03.2019
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BG13.06.2019
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GR14.06.2019
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IE25.11.2019
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BE30.11.2019
Former [2021/34]HU25.11.2016
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BE30.11.2019
Former [2021/33]HU25.11.2016
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SM13.03.2019
TR13.03.2019
BG13.06.2019
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GR14.06.2019
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IE25.11.2019
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BE30.11.2019
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BG13.06.2019
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GR14.06.2019
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PT13.07.2019
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BE30.11.2019
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SK13.03.2019
SM13.03.2019
TR13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
IS13.07.2019
PT13.07.2019
IE25.11.2019
LU25.11.2019
BE30.11.2019
Former [2020/46]AL13.03.2019
CZ13.03.2019
DK13.03.2019
EE13.03.2019
ES13.03.2019
FI13.03.2019
HR13.03.2019
IT13.03.2019
LT13.03.2019
LV13.03.2019
MC13.03.2019
NL13.03.2019
PL13.03.2019
RO13.03.2019
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SK13.03.2019
SM13.03.2019
TR13.03.2019
BG13.06.2019
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GR14.06.2019
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BG13.06.2019
NO13.06.2019
GR14.06.2019
IS13.07.2019
PT13.07.2019
LU25.11.2019
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PL13.03.2019
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SM13.03.2019
TR13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
IS13.07.2019
PT13.07.2019
LU25.11.2019
Former [2020/17]AL13.03.2019
CZ13.03.2019
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ES13.03.2019
FI13.03.2019
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BG13.06.2019
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GR14.06.2019
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PL13.03.2019
RO13.03.2019
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SM13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
IS13.07.2019
PT13.07.2019
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FI13.03.2019
HR13.03.2019
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RO13.03.2019
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SM13.03.2019
BG13.06.2019
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GR14.06.2019
IS13.07.2019
PT13.07.2019
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PL13.03.2019
RO13.03.2019
RS13.03.2019
SE13.03.2019
SK13.03.2019
SM13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
PT13.07.2019
Former [2019/51]AL13.03.2019
CZ13.03.2019
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FI13.03.2019
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LV13.03.2019
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RS13.03.2019
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SM13.03.2019
BG13.06.2019
NO13.06.2019
GR14.06.2019
PT13.07.2019
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EE13.03.2019
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FI13.03.2019
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Cited inInternational search[XY]WO0045929  (CPBD INC [US]) [X] 12-14 * figure 5; claim 3 * * page 27, lines 20-22; claim 12 * * page 31, lines 4-6 * * page 23, lines 26-27 * * page 46, lines 9-14 * * page 18, lines 15-20 * * page 48, lines 21-28 * * page 40, lines 13-19 * [Y] 1-11;
 [A]WO2004106915  (WATERS INVESTMENTS LTD [US], et al) [A] 1,12 * page 4, paragraph 3; figure 7; claims 1,2 *;
 [Y]DE102010047427  (KARLSRUHER INST TECHNOLOGIE [DE]) [Y] 1-11 * claims 1,2-6,11 * * paragraphs [0031] - [0032] *;
 [A]US2014251913  (LACKI KAROL [SE], et al) [A] 1,12 * figures 1,5,11; claims 1,20 * * paragraph [0066] * * paragraph [0057] *
 [YA]  - BORTOLATO SANTIAGO A ET AL, "Chemometric processing of second-order liquid chromatographic data with UV-vis and fluorescence detection. A comparison of multivariate curve resolution and parallel factor analys", ANALYTICA CHIMICA ACTA, ELSEVIER, AMSTERDAM, NL, (20140714), vol. 842, doi:10.1016/J.ACA.2014.07.007, ISSN 0003-2670, pages 11 - 19, XP029045047 [Y] 1,5 * abstract * * page 18, column r * [A] 12

DOI:   http://dx.doi.org/10.1016/j.aca.2014.07.007
 [YA]  - GARCIA-MARTIN S ET AL, "Solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) determination of volatile compounds in orujo spirits: Multivariate chemometric characterisation", FOOD CHEMISTRY, ELSEVIER LTD, NL, vol. 118, no. 2, doi:10.1016/J.FOODCHEM.2009.04.105, ISSN 0308-8146, (20100115), pages 456 - 461, (20090503), XP026497695 [Y] 1 * abstract * * page 460, column r, paragraph 4 * [A] 12

DOI:   http://dx.doi.org/10.1016/j.foodchem.2009.04.105
OppositionWO0045929
 WO2010019814
 WO2012045396
 US5457260
 WO2004106915
 US7606681
 US2009312851
 WO2010151214
 DE102010047427
 WO2014166799
    - Abel, S. et al, "Optimizing control of simulated moving beds -experimental implementation", Journal of Chromatography A, (20050000), vol. 1092, pages 2 - 16, XP005091366

DOI:   http://dx.doi.org/10.1016/j.chroma.2005.04.101
    - HARYNUK et al., "Application of Chemometrics Published online to the Interpretation of Analytical Separations", Chemometrics in Practical Applications, (20120323), XP055650806
    - SANTIAGO A. BORTOLATO et al., "Chemometric processing of second-order liquid Chromatographie data with UV-vis and fluorescence detection. A comparison of multivariate curve resolution and parallel factor analysis 2", Analytica Chimica Acta, (2014), vol. 842, pages 11 - 19, XP029045047

DOI:   http://dx.doi.org/10.1016/j.aca.2014.07.007
    - S. GARCIA-MARTIN et al., "Solid-phase microextraction gas chromato- graphy-mass spectrometry (HS-SPME-GC-MS) determination of volatile compounds in orujo spirits: Multivariate chemometric characterisation", FOOD CHEMISTRY,, (2010), vol. 118, no. 2, pages 456 - 461, XP026497695

DOI:   http://dx.doi.org/10.1016/j.foodchem.2009.04.105
    - N. BRESTRICH et al., "A Tool for Selective Inline Quantification of Co- Eluting Proteins in Chromatography Using Spectral Analysis and Partial Least Squares", Biotechnology and Bioengineering, (20140700), vol. 111, no. 7, pages 1365 - 1373, XP055663656
    - N. BRESTRICH et al., "Advances in Inline Quantification of Co-Eluting Pro- teins in Chromatography: Process-Data-Based Model Calibration and Ap- plication Towards Real-Life Separation Issues", Biotechnology and Bioengineering, (20150700), vol. 112, no. 7, pages 1406 - 1416, XP055663660
    - C. ÜNDEY et al., "Applied advanced process analytics in biopharmaceutical manufacturing: Challenges and prospects in real-time monitoring and control", Journal of Process Control, (20100000), vol. 20, pages 1009 - 1018, XP027265910
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