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Extract from the Register of European Patents

EP About this file: EP3328873

EP3328873 - TARGETED OLIGONUCLEOTIDES [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  29.06.2020
Database last updated on 25.09.2024
FormerRequest for examination was made
Status updated on  04.05.2018
FormerThe international publication has been made
Status updated on  03.02.2017
Most recent event   Tooltip12.06.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Caris Science, Inc.
750 West John Carpenter Freeway, Suite 800
Irving, TX 75039 / US
[2019/14]
Former [2018/23]For all designated states
Caris Science, Inc.
6655 N. MacArthur Boulevard
Irving, TX 75039 / US
Inventor(s)01 / O'NEILL, Heather
1252 W Laguna Azul Avenue
Mesa, AZ 85202 / US
02 / MAYER, Gunter
Martin-Legrosstrasse 59
53123 Bonn / DE
03 / MIGLARESE, Mark
1620 East Silverwood Drive
Phoenix, AZ 85048 / US
04 / SPETZLER, David
6045 N. 40th Street
Paradise Valley, AZ 85253 / US
 [2018/23]
Representative(s)Patent Boutique LLP
10A Printing House Yard
Hackney Road
London E2 7PR / GB
[N/P]
Former [2018/23]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date16831384.928.07.2016
[2018/23]
WO2016US44595
Priority number, dateUS201562198051P28.07.2015         Original published format: US 201562198051 P
US201562198110P28.07.2015         Original published format: US 201562198110 P
US201562220652P18.09.2015         Original published format: US 201562220652 P
US201562239226P08.10.2015         Original published format: US 201562239226 P
US201562269671P18.12.2015         Original published format: US 201562269671 P
US201662305536P09.03.2016         Original published format: US 201662305536 P
[2018/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017019918
Date:02.02.2017
Language:EN
[2017/05]
Type: A1 Application with search report 
No.:EP3328873
Date:06.06.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 02.02.2017 takes the place of the publication of the European patent application.
[2018/23]
Search report(s)International search report - published on:US02.02.2017
ClassificationIPC:G01N33/50, C12N15/113, C07H21/02
[2019/14]
CPC:
C07H21/00 (EP,IL,US); C12N15/10 (EP,IL,US); C07H19/173 (US);
A61K47/6911 (US); A61K47/6929 (US); A61K9/0014 (US);
A61K9/0019 (US); A61K9/0053 (US); A61P25/28 (EP,US);
A61P29/00 (EP,US); A61P31/00 (EP,US); A61P35/02 (EP,US);
A61P37/00 (EP,US); A61P9/00 (EP,US); C07H19/09 (US);
C07H19/19 (US); C12N15/113 (IL); C12N15/115 (EP,US);
C12Q1/6886 (EP,US); G01N33/5308 (EP,US); G01N33/57484 (EP,US);
G01N33/68 (EP,US); G06T7/0012 (US); C12N2310/16 (EP,US);
C12N2320/10 (EP,US); C12Q2600/158 (EP,US) (-)
Former IPC [2018/23]C07H19/173, C07H21/00, C07H19/19, C07H19/09
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/23]
TitleGerman:GEZIELTE OLIGONUKLEOTIDE[2018/23]
English:TARGETED OLIGONUCLEOTIDES[2018/23]
French:OLIGONUCLÉOTIDES CIBLÉS[2018/23]
Entry into regional phase08.02.2018National basic fee paid 
08.02.2018Search fee paid 
08.02.2018Designation fee(s) paid 
08.02.2018Examination fee paid 
Examination procedure08.02.2018Examination requested  [2018/23]
08.02.2018Date on which the examining division has become responsible
07.10.2019Amendment by applicant (claims and/or description)
02.07.2020Despatch of a communication from the examining division (Time limit: M04)
04.09.2020Reply to a communication from the examining division
14.06.2021Despatch of a communication from the examining division (Time limit: M04)
20.10.2021Reply to a communication from the examining division
Fees paidRenewal fee
27.07.2018Renewal fee patent year 03
29.07.2019Renewal fee patent year 04
27.07.2020Renewal fee patent year 05
27.07.2021Renewal fee patent year 06
27.07.2022Renewal fee patent year 07
27.07.2023Renewal fee patent year 08
12.06.2024Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Rights in Rem or Legal Means of Executiondeleted
[2024/17]
Former [2019/14]ID:01
For:AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Date:19.12.2018
[2024/17]
Documents cited:Search[XI]WO2011147193  (UNIV HONG KONG [CN], et al) [X] 1,6,8 * claim 2; sequence 7 * [I] 2,6-14;
 [XI]JP2013094067  (HITACHI HIGH TECH CORP) [X] 1,6,8 * page 8; sequences 12,14 * [I] 2,6-14;
 [X]  - "Pseudorca crassidens DNA, BAC clone: QGB1-271M02_F, 5'end.", EMBL, (20131212), Database accession no. DE820782, URL: EBI, XP002789005 [X] 1,6,8 * the whole document *
 [XI]  - KOUTSIOUMPA MARINA ET AL, "Cell surface nucleolin as a target for anti-cancer therapies", RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, BENTHAM SCIENCE, SHARJAH, UNITED ARAB EMIRATES, (20140430), vol. 9, no. 2, doi:10.2174/1574892808666131119095953, ISSN 2212-3970, pages 137 - 152, XP009511363 [X] 1,3-6,8 * page 143 * [I] 1-15

DOI:   http://dx.doi.org/10.2174/1574892808666131119095953
 [XI]  - MONGELARD FABIEN ET AL, "AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia", CURRENT OPINION IN MOLECULAR THERAPEUTICS, THOMSON REUTERS (SCIETIFIC) LTD, (20100131), vol. 12, no. 1, ISSN 2040-3445, pages 107 - 114, XP009511364 [X] 1,3-6,8 * the whole document * [I] 1-15
    [XDPI] - FELIPE OPAZO ET AL, "Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer", MOLECULAR THERAPY-NUCLEIC ACIDS, (20150901), vol. 4, doi:10.1038/mtna.2015.25, ISSN 2162-2531, pages 1 - 10, XP055561058 [XDP] 1-6,8 * the whole document * [I] 1-8

DOI:   http://dx.doi.org/10.1038/mtna.2015.25
 [T]  - Sonal S Tonapi, "Abstract 2469: The B-cell lymphoma specific aptamer C10.36 binds a ribonucleoprotein complex on the cell surface of cancer cells | Cancer Research", (20170701), URL: http://cancerres.aacrjournals.org/content/77/13_Supplement/2469, (20190218), XP055558346

DOI:   http://dx.doi.org/10.1158/1538-7445.AM2017-2469
 [T]  - TONAPI SONAL S ET AL, "Aptamer C10.36 Reveals a Ribonucleoprotein Complex on the Surface of Non-Hodgkin Lymphoma Cells Providing Candidates for Multi-Target Therapeutics", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (20171207), Database accession no. PREV201800668307, XP002789040 [T] * abstract *
    [ ] - BLOOD, 59TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY (ASH); ATLANTA, GA, USA; DECEMBER 09 -12, 2017, (20171207), vol. 130, no. Suppl. 1, ISSN 0006-4971(print), page 3346
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