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EP3328403
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EP About this file: EP3328403
| EP3328403 - EXOSOME COMPOSITIONS AND USE THEREOF FOR SOFT TISSUE REPAIR [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 26.05.2023 Database last updated on 16.11.2024 | |
| Former | Examination is in progress Status updated on 27.08.2020 | ||
| Former | Request for examination was made Status updated on 04.05.2018 | ||
| Former | The international publication has been made Status updated on 11.02.2017 | Most recent event Tooltip | 26.05.2023 | Application deemed to be withdrawn | published on 28.06.2023 [2023/26] | Applicant(s) | For all designated states Zen-Bio, Inc. 3200 East Highway 54 Suite 100 Research Triangle Park NC 27709 / US | [2018/23] | Inventor(s) | 01 /
LUDLOW, John, W. 3200 East Highway 54 Suite 100 Research Triangle Park NC 27709 / US | 02 /
BUEHRER, Benjamin 3200 East Highway 54 Suite 100 Research Triangle Park NC 27709 / US | 03 /
PIERACCINI, Peter 3200 East Highway 54 Suite 100 Research Triangle Park NC 27709 / US | [2018/23] | Representative(s) | Gilani, Anwar, et al Venner Shipley LLP 406 Science Park Milton Road Cambridge CB4 0WW / GB | [N/P] |
| Former [2018/23] | Gilani, Anwar, et al Venner Shipley LLP Byron House Cambridge Business Park Cowley Road Cambridge CB4 0WZ / GB | Application number, filing date | 16833568.5 | 28.07.2016 | [2018/23] | WO2016US44453 | Priority number, date | US201562199696P | 31.07.2015 Original published format: US 201562199696 P | [2018/23] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017023689 | Date: | 09.02.2017 | Language: | EN | [2017/06] | Type: | A1 Application with search report | No.: | EP3328403 | Date: | 06.06.2018 | Language: | EN | The application published by WIPO in one of the EPO official languages on 09.02.2017 takes the place of the publication of the European patent application. | [2018/23] | Search report(s) | International search report - published on: | US | 09.02.2017 | (Supplementary) European search report - dispatched on: | EP | 15.03.2019 | Classification | IPC: | A61K35/28, C12N5/0775, A61P1/02, A61P17/02, A61P19/04 | [2019/16] | CPC: |
A61K35/28 (EP,US);
A61K31/74 (EP,US);
A61K35/545 (US);
A61K38/1709 (EP,US);
A61K8/14 (US);
A61K8/675 (US);
A61K8/678 (US);
A61P1/02 (EP,US);
A61P17/02 (EP,US);
A61P19/04 (EP,US);
A61Q19/007 (US);
A61Q19/08 (US);
C12N15/88 (US);
C12N5/0605 (US);
C12N5/0606 (US);
C12N5/0607 (US);
C12N5/0667 (EP,US);
C12N5/0668 (EP,US);
|
| Former IPC [2018/23] | A61K35/28, A61K35/35, A61K35/50, C12N5/077, C12N5/0775 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/23] | Title | German: | EXOSOME ZUSAMMENSETZUNGEN UND VERWENDUNG DAVON ZUR WEICHGEWEBEREPARATUR | [2018/23] | English: | EXOSOME COMPOSITIONS AND USE THEREOF FOR SOFT TISSUE REPAIR | [2018/23] | French: | COMPOSITIONS D'EXOSOME ET LEUR UTILISATION POUR LA RÉPARATION DE TISSUS MOUS | [2018/23] | Entry into regional phase | 23.02.2018 | National basic fee paid | 23.02.2018 | Search fee paid | 23.02.2018 | Designation fee(s) paid | 23.02.2018 | Examination fee paid | Examination procedure | 23.02.2018 | Examination requested [2018/23] | 23.02.2018 | Date on which the examining division has become responsible | 11.10.2019 | Amendment by applicant (claims and/or description) | 26.08.2020 | Despatch of a communication from the examining division (Time limit: M06) | 25.02.2021 | Reply to a communication from the examining division | 01.02.2023 | Application deemed to be withdrawn, date of legal effect [2023/26] | 21.02.2023 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2023/26] | Fees paid | Renewal fee | 19.07.2018 | Renewal fee patent year 03 | 25.07.2019 | Renewal fee patent year 04 | 20.07.2020 | Renewal fee patent year 05 | 09.07.2021 | Renewal fee patent year 06 | Penalty fee | Additional fee for renewal fee | 31.07.2022 | 07 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]US2011003008 (LIM SAI KIANG [SG]) [X] 7-15 * claim - *; | [X]WO2014013029 (UNIV DUISBURG ESSEN [DE]) [X] 7-15 * example - *; | [X]US2014065240 (MITSIALIS S ALEXANDER [US], et al) [X] 7-15 * example - *; | [X]WO2014197747 (UNIV COLUMBIA [US]) [X] 7-15 * examples 2, 8 *; | [A]CN104488850 (GUANGZHOU SALIAI STEMCELL SCIENCE & TECHNOLOGY CO LTD)[A] 3,9; | [X] - LUDLOW J ET AL, "Mesenchymal Stem Cell Exosomes - Potential Regenerative Medicine Application for Tendinopathy", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, (201504), Database accession no. PREV201600122429, XP002788942 [X] 7-15 * abstract * | [ ] - FASEB JOURNAL, EXPERIMENTAL BIOLOGY MEETING 2015; BOSTON, MA, USA; MARCH 28 -APRIL 01, 2015, (201504), vol. 29, no. Suppl. 1, ISSN 0892-6638(print), page 1018.3 | [XP] - BASU J & LUDLOW J, "Wound Healing, Skin Regeneration and Tendon Repair with MSC-sourced Exosomes: Functional Evaluation In Vitro and In Vivo and Methods of Manufacture", TISSUE ENGINEERING PART A, & 4th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS); Boston, MA, USA; 8-11 September 2015, (201509), vol. 21, no. Suppl. 1, pages S112 - S113, XP055557089 [XP] 7-15 * abstract * | [XP] - BASU J & LUDLOW J, "Exosomes for repair, regeneration and rejuvenation", EXPERT OPINION ON BIOLOGICAL THERAPY, (20160128), vol. 16, no. 4, doi:10.1517/14712598.2016.1131976, ISSN 1471-2598, pages 489 - 506, XP055557079 [XP] 7-15 * the whole document * DOI: http://dx.doi.org/10.1517/14712598.2016.1131976 | [X] - FENG Y ET AL, "Heat Shock Improves Sca-1 + Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR-34a/HSP70 Pathway", STEM CELLS, (201402), vol. 32, no. 2, doi:10.1002/stem.1571, ISSN 1066-5099, pages 462 - 472, XP055362024 [X] 1-15 * the whole document * DOI: http://dx.doi.org/10.1002/stem.1571 | [ ] - FENG Y ET AL, "Supplemental Information", STEM CELLS, (201402), vol. 32, no. 2, doi:10.1002/stem.1571, ISSN 1066-5099, pages 462 - 472, XP055557114 DOI: http://dx.doi.org/10.1002/stem.1571 | International search | [Y]WO2012053976 (AGENCY SCIENCE TECH & RES [SG], et al) [Y] 12, 18-21, 24-25 * ; page 3, line 20; abstract; page 4, lines 9-10, 24-26, 29; page 32, lines 4, 10-11; page 34, lines 1-2; page 46, lines 21-22 *; | [Y]US2013195899 (ICHIM THOMAS [US], et al) [Y] 8-9, 15-16 * ; paragraphs [0007]-[0009] *; | [Y]US8722406 (REITER MANFRED [AT], et al) [Y] 7 * ; column 1, lines 28-29, 33-35; claim 1 *; | [Y]CN104488850 (GUANGZHOU SALIAI STEMCELL SCIENCE & TECHNOLOGY CO LTD) [Y] 5, 13 * ; paragraphs [0044], [0046] *; | [Y]US2015166951 (MEYN III MALCOLM A [US], et al) [Y] 22-23* ; paragraphs [0087], [0093], [0097], [0110], [0112] *; | [XY] - FENG, Y et al., "Heat Shock Improves Sca-11 Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR-34a/HSP70 Pathway.", STEM CELLS., (20131007), vol. 32, no. 2, pages 462 - 472, XP055362024 [X] 1-4, 6, 10-11, 14, 17 * ; abstract; page 468, column 2, paragraph 1; supplemental information, page 1, paragraph 2; supplemental information, page 3, paragraph 4; DOI: 10.1002/stem.1571 * [Y] 5, 7-9, 12-13, 15-16, 18-25 DOI: http://dx.doi.org/10.1002/stem.1571 |