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EP About this file: EP3337490

EP3337490 - COMPOSITIONS AND MULTIPLEXED SYSTEMS FOR COUPLED CELL-FREE TRANSCRIPTION-TRANSLATION AND PROTEIN SYNTHESIS AND METHODS FOR USING THEM [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 14.06.2024 Database last updated on 08.10.2024
Former	Examination is in progress Status updated on 02.07.2021
Former	Request for examination was made Status updated on 25.05.2018
Former	The international publication has been made Status updated on 25.02.2017
Most recent event Tooltip	14.06.2024	Application deemed to be withdrawn	published on 17.07.2024 [2024/29]
Applicant(s)	For all designated states Genomatica, Inc. 4757 Nexus Center Drive San Diego, CA 92121 / US
	[2018/26]
Inventor(s)	01 / CULLER, Stephanie Persephone Biome, Inc. JLABS 3120 Merryfield Row San Diego, California 92121 / US
	02 / CHEN, Ihsiung Brandon Genomatica Inc. 4757 Nexus Center Drive San Diego, California 92121 / US
	03 / PHARKYA, Priti Genomatica Inc. 4757 Nexus Center Drive San Diego, California 92121 / US
	04 / VAN DIEN, Steve Genomatica Inc. 4757 Nexus Center Drive San Diego, California 92121 / US
	05 / BARTON, Nelson Genomatica Inc. 4757 Nexus Center Drive San Diego, California 92121 / US
	[2018/26]
Representative(s)	Cantaluppi, Stefano, et al Cantaluppi & Partners S.r.l. Via A. Canova, 2 20145 Milano / IT
	[N/P]
Former [2018/26]	Ghirardi, Valeria, et al Cantaluppi & Partners S.r.l. Via Strobel, 8 20133 Milano / IT
Application number, filing date	16837891.7	19.08.2016
	[2018/26]
	WO2016US47704
Priority number, date	US201562207844P	20.08.2015 Original published format: US 201562207844 P
	[2018/26]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2017031399
	Date:	23.02.2017
	Language:	EN
	[2017/08]
	Type:	A1 Application with search report
	No.:	EP3337490
	Date:	27.06.2018
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 23.02.2017 takes the place of the publication of the European patent application.
	[2018/26]
Search report(s)	International search report - published on:	US	23.02.2017
	(Supplementary) European search report - dispatched on:	EP	24.06.2019
Classification	IPC:	C12P19/34, C12P21/02, C40B40/04, C12N15/52	[2019/16]
	CPC:	A61K35/66 (EP,US); C12Q1/6869 (US); A61K36/02 (US); A61K36/06 (US); C12N15/09 (US); C12N5/16 (US); (+) C12P19/34 (EP,US); C12P21/02 (EP,US); C40B40/04 (EP,US); A61K2236/15 (US); A61K2236/30 (US); C12N2330/50 (US); Y02A50/30 (EP,US) (-)
	C-Set:	A61K35/66, A61K35/12 (EP,US)
	Former IPC [2018/26]	A61K35/12, A61K48/00, C12N5/00, C12N5/02, C12N15/09, C12N5/10
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/26]
Extension states	BA	13.02.2018
	ME	13.02.2018
Validation states	MA	13.02.2018
	MD	13.02.2018
Title	German:	ZUSAMMENSETZUNGEN UND MULTIPLEXSYSTEME ZUR GEKOPPELTEN ZELLFREIEN TRANSKRIPTION-TRANSLATION UND PROTEINSYNTHESE UND VERFAHREN ZUR VERWENDUNG DAVON	[2018/26]
	English:	COMPOSITIONS AND MULTIPLEXED SYSTEMS FOR COUPLED CELL-FREE TRANSCRIPTION-TRANSLATION AND PROTEIN SYNTHESIS AND METHODS FOR USING THEM	[2018/26]
	French:	COMPOSITIONS ET SYSTÈMES MULTIPLEXÉS POUR LA TRANSCRIPTION-TRADUCTION ET LA SYNTHÈSE PROTÉIQUE COUPLÉES SANS CELLULES ET PROCÉDÉS POUR LES UTILISER	[2018/26]
Entry into regional phase	13.02.2018	National basic fee paid
	13.02.2018	Search fee paid
	13.02.2018	Designation fee(s) paid
	13.02.2018	Examination fee paid
Examination procedure	13.02.2018	Examination requested [2018/26]
	13.02.2018	Date on which the examining division has become responsible
	10.01.2020	Amendment by applicant (claims and/or description)
	05.07.2021	Despatch of a communication from the examining division (Time limit: M06)
	13.01.2022	Reply to a communication from the examining division
	01.03.2024	Application deemed to be withdrawn, date of legal effect [2024/29]
	22.03.2024	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2024/29]
Fees paid	Renewal fee
	10.08.2018	Renewal fee patent year 03
	15.08.2019	Renewal fee patent year 04
	13.08.2020	Renewal fee patent year 05
	13.08.2021	Renewal fee patent year 06
	11.08.2022	Renewal fee patent year 07
	Penalty fee
	Additional fee for renewal fee
	31.08.2023	08 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]US2013316397 (AIREN ISOKEN [US], et al) [X] 1-3 * abstract * * paragraphs [0010] , [0 42] *;
		[XY] - WILLIAM C. YANG ET AL, "Simplifying and streamlining Escherichia coli-based cell-free protein synthesis", BIOTECHNOLOGY PROGRESS, (20120101), vol. 28, no. 2, doi:10.1002/btpr.1509, ISSN 8756-7938, pages 413 - 420, XP055024064 [X] 1-3 * abstract * * page 3, column r, paragraph l - page 5, column r, paragraph 2; figure 3 * * page 7, column l, paragraph 2 - column r, paragraph 2; figure 6 * [Y] 4 DOI: http://dx.doi.org/10.1002/btpr.1509
		[X] - BAPTISTE PANTHU ET AL, "In vitro translation in a hybrid cell free lysate with exogenous cellular ribosomes", BIOCHEMICAL JOURNAL, GB, (20150501), vol. 467, no. 3, doi:10.1042/BJ20141498, ISSN 0264-6021, pages 387 - 398, XP055565494 [X] 1-4 * abstract * * page 388, column r, paragraph 2 - page 389, column l, paragraph 3 * * page 391, column r, paragraph 1 - page 392, column r, paragraph l; figures 3-5 * DOI: http://dx.doi.org/10.1042/BJ20141498
		[X] - ANDREW M. BORMAN ET AL, "Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation in vitro", NUCLEIC ACIDS RESEARCH, (19950101), vol. 23, no. 18, doi:10.1093/nar/23.18.3656, ISSN 0305-1048, pages 3656 - 3663, XP055565503 [X] 1-3 * abstract * * page 3657, column r, paragraph 2 - page 3659, column r, paragraph 2; figures 1, 2 * DOI: http://dx.doi.org/10.1093/nar/23.18.3656
		[Y] - Yong Y Wu ET AL, "Prototyping 1,4-butanediol (BDO) biosynthesis pathway in a cell-free transcription-translation (TX-TL) system", bioRxiv, doi:10.1101/017814, (20150409), URL: https://www.biorxiv.org/content/biorxiv/early/2015/04/09/017814.full.pdf, XP055566232 [Y] 4 * abstract * * pages 3-6; figures 4, 5 * DOI: http://dx.doi.org/10.1101/017814
		[YD] - ZACHARY Z. SUN ET AL, "Linear DNA for Rapid Prototyping of Synthetic Biological Circuits in an Escherichia coli Based TX-TL Cell-Free System", ACS SYNTHETIC BIOLOGY, Washington, DC,USA, (20140101), vol. 3, no. 6, doi:10.1021/sb400131a, ISSN 2161-5063, pages 387 - 397, XP055479595 [YD] 4 * the whole document * DOI: http://dx.doi.org/10.1021/sb400131a
		[AP] - Abel C Chiao ET AL, "Development of prokaryotic cell-free systems for synthetic biology", bioRxiv, doi:10.1101/048710, (20160415), URL: https://www.biorxiv.org/content/biorxiv/early/2016/04/15/048710.full-text.pdf, XP055566200 [AP] 1-4 * the whole document * DOI: http://dx.doi.org/10.1101/048710
		[A] - GANGULY T ET AL, "A cell-free assay using cytoplasmic cell extracts to study rejoining of radiation-induced DNA double-strand breaks in human cell nuclei", INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, TAYLOR & FRANCIS, GB, (19950101), vol. 68, no. 4, ISSN 0955-3002, pages 447 - 457, XP008121499 [A] 1 * abstract * DOI: http://dx.doi.org/10.1080/09553009514551411
	International search	[Y]US2003124689 (SHERMAN DAVID H [US], et al) [Y] 600-601, 602/600-601 * ; paragraphs [0017], [0018], [0044], [0135]. [0150] *;
		[A]US6753457 (WANGH LAWRENCE J [US]) [A] 1-3, 4/1-3, 5/4/1-3, 600-601 , 602/600-601* ; entire document *;
		[XY]US2005014258 (COLLAS PHILIPPE [NO], et al) [X] 1-3, 4/1-3, 5/4/1-3 * ; paragraphs [0005], [0012], [0022], [0025], [0031], [0086], [0089], [0166] * [Y] 600-601, 602/600-601;
		[A]US2015056295 (GAMMELSAETER RUNHILD [NO], et al) [A] 1-3, 4/1-3, 5/4/1-3, 600-601, 602/600-601 * ; entire document *

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