EP3350188 - INHIBITORS OF TRYPTOPHAN DIOXYGENASES (IDO1 AND TDO) AND THEIR USE IN THERAPY [Right-click to bookmark this link] | Status | The patent has been granted Status updated on 09.02.2024 Database last updated on 22.08.2024 | |
Former | Grant of patent is intended Status updated on 23.05.2023 | ||
Former | Examination is in progress Status updated on 26.11.2021 | ||
Former | Request for examination was made Status updated on 22.06.2018 | ||
Former | The international publication has been made Status updated on 04.03.2017 | Most recent event Tooltip | 02.08.2024 | Lapse of the patent in a contracting state New state(s): LV | published on 04.09.2024 [2024/36] | Applicant(s) | For all designated states Auckland Uniservices Limited Level 10, 49 Symonds Street Auckland 1010 / NZ | [2023/44] |
Former [2018/30] | For all designated states AUCKLAND UNISERVICES LIMITED Level 10, 70 Symonds Street Auckland / NZ | Inventor(s) | 01 /
PALMER, Brian Desmond 9 Monet Grove West Harbour Auckland 0618 / NZ | 02 /
CHING, Lai-Ming 9 Monet Grove West Harbour Auckland 0618 / NZ | [2018/30] | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [2024/11] |
Former [2018/30] | Watson, Robert James, et al Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB | Application number, filing date | 16839685.1 | 25.08.2016 | [2018/30] | WO2016NZ50135 | Priority number, date | NZ20140157115 | 27.08.2015 Original published format: NZ 15711514 | [2018/30] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2017034420 | Date: | 02.03.2017 | Language: | EN | [2017/09] | Type: | A1 Application with search report | No.: | EP3350188 | Date: | 25.07.2018 | Language: | EN | The application published by WIPO in one of the EPO official languages on 02.03.2017 takes the place of the publication of the European patent application. | [2018/30] | Type: | B1 Patent specification | No.: | EP3350188 | Date: | 13.03.2024 | Language: | EN | [2024/11] | Search report(s) | International search report - published on: | AU | 02.03.2017 | (Supplementary) European search report - dispatched on: | EP | 01.03.2019 | Classification | IPC: | C07D498/04, A61K31/437, A61P9/04, A61P13/12, A61P15/00, A61P25/00, A61P27/12, A61P29/00, A61P31/00, A61P35/00 | [2018/30] | CPC: |
C07D498/04 (EP,KR,US);
A61K31/437 (EP,KR,US);
A61K45/06 (KR,US);
A61P35/00 (EP,KR,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2018/30] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | INHIBITOREN VON TRYPTOPHANDIOXYGENASEN (IDO1 UND TDO) UND DEREN VERWENDUNG IN DER THERAPIE | [2018/30] | English: | INHIBITORS OF TRYPTOPHAN DIOXYGENASES (IDO1 AND TDO) AND THEIR USE IN THERAPY | [2018/30] | French: | INHIBITEURS DES TRYPTOPHANE-DIOXYGÉNASES (IDO1 ET TDO) ET LEUR UTILISATION EN THÉRAPIE | [2018/30] | Entry into regional phase | 14.02.2018 | National basic fee paid | 14.02.2018 | Search fee paid | 14.02.2018 | Designation fee(s) paid | 14.02.2018 | Examination fee paid | Examination procedure | 05.02.2018 | Date on which the examining division has become responsible | 14.02.2018 | Examination requested [2018/30] | 27.09.2019 | Amendment by applicant (claims and/or description) | 25.11.2021 | Despatch of a communication from the examining division (Time limit: M06) | 31.05.2022 | Reply to a communication from the examining division | 20.09.2022 | Despatch of a communication from the examining division (Time limit: M04) | 13.01.2023 | Reply to a communication from the examining division | 24.05.2023 | Communication of intention to grant the patent | 26.09.2023 | Fee for grant paid | 26.09.2023 | Fee for publishing/printing paid | 26.09.2023 | Receipt of the translation of the claim(s) | Fees paid | Renewal fee | 21.08.2018 | Renewal fee patent year 03 | 02.08.2019 | Renewal fee patent year 04 | 13.08.2020 | Renewal fee patent year 05 | 27.08.2021 | Renewal fee patent year 06 | 31.08.2022 | Renewal fee patent year 07 | 04.02.2024 | Renewal fee patent year 08 | Penalty fee | Additional fee for renewal fee | 31.08.2023 | 08   M06   Fee paid on   04.02.2024 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | BG | 13.03.2024 | ES | 13.03.2024 | FI | 13.03.2024 | HR | 13.03.2024 | LT | 13.03.2024 | LV | 13.03.2024 | NO | 13.06.2024 | RS | 13.06.2024 | GR | 14.06.2024 | [2024/36] |
Former [2024/35] | BG | 13.03.2024 | |
ES | 13.03.2024 | ||
FI | 13.03.2024 | ||
HR | 13.03.2024 | ||
LT | 13.03.2024 | ||
NO | 13.06.2024 | ||
RS | 13.06.2024 | ||
GR | 14.06.2024 | ||
Former [2024/34] | BG | 13.03.2024 | |
FI | 13.03.2024 | ||
HR | 13.03.2024 | ||
LT | 13.03.2024 | ||
NO | 13.06.2024 | ||
RS | 13.06.2024 | ||
GR | 14.06.2024 | ||
Former [2024/33] | LT | 13.03.2024 | |
NO | 13.06.2024 | Documents cited: | Search | [A]EP1813606 (TAKEDA PHARMACEUTICAL [JP]) [A] 1-21 * the whole document * * in particular example 38 *; | [A]WO2014186035 (CURADEV PHARMA PRIVATE LTD [IN]) [A] 1-21 * the whole document *; | [E]RU2619120 (FED GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIYA K [RU]) [E] 1-21* the whole document *; | [A] - MARK S. TICHENOR ET AL, "Heteroaryl urea inhibitors of fatty acid amide hydrolase: Structure-mutagenicity relationships for arylamine metabolites", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, AMSTERDAM, NL, (20121201), vol. 22, no. 24, doi:10.1016/j.bmcl.2012.10.076, ISSN 0960-894X, pages 7357 - 7362, XP055477985 [A] 1-21 * the whole document * * in particular Scheme 2 on page 7359, compounds 18m to 18p * DOI: http://dx.doi.org/10.1016/j.bmcl.2012.10.076 | International search | [A]WO2005089753 (JANSSEN PHARMACEUTICA NV [BE], et al) [A] 1-80 * Page 2 lines 22-28, page 2 line 30 - page 4 line 13, page 10 line 10 - page 11 line 21, page 20 Scheme 2, Claims 1 and 9. *; | [A]US2008176915 (MERLA BEATRIX [DE], et al) [A] 1-80 * Paragraphs [0006]-[0026], Claims 1, 20 and 21. *; | [A]US2008312301 (MERLA BEATRIX [DE], et al) [A] 1-80 * Paragraphs [0005]-[0044], Claims 35 and 69-72. *; | [PA]WO2016024233 (AUCKLAND UNISERVICES LTD [NZ], et al) [PA] 1-80* Page 2 line 19 - page 5 line 13, page 6 lines 18-32, Examples, Claims 1, 23-26, 28, 31, 34-36 and 39. *; | [X] - POREBA, K. et al., "Synthesis and antibacterial activity of new sulfonamide isoxazolo[5,4- b]pyridine derivatives", Acta Poloniae Pharmaceutica - Drug Research, (20150000), vol. 72, no. 4, pages 727 - 735, XP055515617 [X] 1, 2, 5, 6, 14-17, 31-33 and 67-80 * . Page 728 left column line 29 - page 729 left column line 11, page 729 right column line 35 - page 730 left column line 43, page 731 left column line 22 - right column line 2 Section In vitro antibacterial activity, page 731 right column lines 3-8 Section In vitro cytotoxicity, page 732 Table 2, pa * | [X] - POR?BA, K. et al., "Synthesis and Antiproliferative Activity In Vitro of New 3- Substituted Aminoisoxazolo[5,4-b]pyridines", Acta Poloniae Pharmaceutica - Drug Research, (20030000), vol. 60, no. 4, pages 293 - 301, XP 055366599 [X] 1, 2, 5, 6, 14-17, 31-33 and 67-78 * Pages 295-297 Table 1, page 299 Scheme 1, page 300 Table 2 and page 301 left column lines 5-9. * | by applicant | WO2015082499 | - UYTTENHOVE et al., J. Nat. Med., (20030000), vol. 9, page 1269 | - ZHENG et al., J. Immunol., (20060000), vol. 177, page 5639 | - CADYSONO, Arch. Biochem. Biophys., (19910000), vol. 291, page 326 | - HOU et al., Cancer Res., (20070000), page 614 | - BRASTIANOS et al., J. Am. Chem. Soc., (20060000), vol. 128, page 16046 | - PEREIRA et al., J. Nat. Prod., (20060000), vol. 69, page 1496 | - KUMAR et al., J. Med. Chem., (20080000), vol. 51, page 1706 | - YUE et al., J. Med. Chem., (20090000), vol. 52, page 7364 | - NEWTON et al., J Clin Oncol., (20120000), vol. 30 | - Goodman and Gilman's The Pharmacological Basis of Therapeutics, McGraw-Hill, (20060000), pages 1225 - 1287 |