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Extract from the Register of European Patents

EP About this file: EP3325633

EP3325633 - RECOMBINANT VECTORS COMPRISING 2A PEPTIDE [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  12.06.2020
Database last updated on 02.11.2024
FormerRequest for examination was made
Status updated on  27.04.2018
FormerThe international publication has been made
Status updated on  11.03.2017
Most recent event   Tooltip12.06.2020Withdrawal of applicationpublished on 15.07.2020  [2020/29]
Applicant(s)For all designated states
Tocagen Inc.
3030 Bunker Hill Street Suite 230
San Diego, CA 92109 / US
[2018/22]
Inventor(s)01 / JOLLY, Douglas, J.
382 Sunset Drive
Encinitas, CA 92024 / US
02 / LIN, Amy, H.
5488 Sonoma Place
San Diego, CA 92130 / US
03 / HOFACRE, Andrew
24942 Rancho Clemente
Laguna Niguel, CA 92677 / US
04 / OSTERTAG, Derek G.
6156 Blue Dawn Trail
San Diego, California 92130 / US
05 / HOGAN, Daniel J.
7712 Parma Lane
San Diego, California 92126 / US
 [2018/22]
Representative(s)Daniels, Jeffrey Nicholas
Page White & Farrer Limited
Bedford House
21A John Street
London WC1N 2BF / GB
[N/P]
Former [2018/22]Daniels, Jeffrey Nicholas
Page White & Farrer
Bedford House
John Street
London WC1N 2BF / GB
Application number, filing date16842998.301.09.2016
[2018/22]
WO2016US49947
Priority number, dateUS201562214884P04.09.2015         Original published format: US 201562214884 P
[2018/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017040815
Date:09.03.2017
Language:EN
[2017/10]
Type: A1 Application with search report 
No.:EP3325633
Date:30.05.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 09.03.2017 takes the place of the publication of the European patent application.
[2018/22]
Search report(s)International search report - published on:US09.03.2017
(Supplementary) European search report - dispatched on:EP14.12.2018
ClassificationIPC:C12N15/867, C12N7/01, A61P35/00
[2018/22]
CPC:
C12N15/86 (EP,KR,US); A61K48/005 (EP,KR,US); A61P35/00 (EP,US);
C07K14/535 (US); C07K14/57 (KR); C07K14/70507 (US);
C07K16/2827 (EP,KR,US); C12N15/1138 (EP,KR,US); C12N9/78 (KR);
A61K48/00 (US); C07K2317/76 (EP,US); C07K2319/30 (EP,US);
C07K2319/50 (EP,KR,US); C07K2319/60 (EP,US); C07K2319/75 (EP,US);
C12N2310/141 (EP,KR,US); C12N2740/13021 (US); C12N2740/13022 (EP,KR,US);
C12N2740/13043 (EP,KR,US); C12N2840/20 (EP,KR,US); C12N2840/203 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/22]
TitleGerman:REKOMBINANTE VEKTOREN MIT 2A-PEPTID[2018/22]
English:RECOMBINANT VECTORS COMPRISING 2A PEPTIDE[2018/22]
French:VECTEURS DE RECOMBINAISON COMPRENANT UN PEPTIDE 2A[2018/22]
Entry into regional phase20.02.2018National basic fee paid 
20.02.2018Search fee paid 
20.02.2018Designation fee(s) paid 
20.02.2018Examination fee paid 
Examination procedure20.02.2018Examination requested  [2018/22]
20.02.2018Date on which the examining division has become responsible
18.07.2019Amendment by applicant (claims and/or description)
05.06.2020Application withdrawn by applicant  [2020/29]
Fees paidRenewal fee
27.09.2018Renewal fee patent year 03
27.09.2019Renewal fee patent year 04
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Documents cited:Search[Y]WO2014066700  (TOCAGEN INC [US]) [Y] 1-16 * abstract * * paragraphs [0007] , [0 10] , [0 12] , [0 14] , [0 52] , [0 65] , [0 66] , [0 72] * * figure 8 *;
 [Y]  - OMAR D PEREZ ET AL, "Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression", MOLECULAR THERAPY, (20120501), vol. 20, no. 9, doi:10.1038/mt.2012.83, ISSN 1525-0016, pages 1689 - 1698, XP055077731 [Y] 1-7,9,13-16 * abstract * * page 1690 * * figures 1, 4 *

DOI:   http://dx.doi.org/10.1038/mt.2012.83
 [Y]  - JIN HEE KIM ET AL, "High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice", PLOS ONE, (20110429), vol. 6, no. 4, doi:10.1371/journal.pone.0018556, page e18556, XP055175691 [Y] 1-16 * abstract * * page 2, column 1, paragraph 3 * * page 5, column 2 - page 7, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0018556
 [Y]  - S YANG ET AL, "Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition", GENE THERAPY, (20080522), vol. 15, no. 21, doi:10.1038/gt.2008.90, ISSN 0969-7128, pages 1411 - 1423, XP055035564 [Y] 1-16 * abstract * * page 2, paragraphs 3, 4 *

DOI:   http://dx.doi.org/10.1038/gt.2008.90
International search[YA]US2012028821  (JAENISCH RUDOLF [US], et al) [Y] 1-6, 9/(1-5), 10, 13-18, 25 -42, 45-46 * . Especially para [0146], [0147], [0151], sheet 13 Fig 13A, SEQ ID NO: 35 * [A] 51-54;
 [YA]WO2014066700  (TOCAGEN INC [US]) [Y] 1-5, 9/(1-5), 10, 13-18, 25 -42, 45-46 * . Especially para [0007], [0011], [0014], [0058], [0072]; claims 2-4, 42-44; SEQ ID NO: 22 * [A] 51-54;
 [A]  - BIENIASZ., "Intrinsic immunity: a front-line defense against viral attack.", Nat Immunol, (20041100), vol. 5, no. 11, pages 1109 - 1115, XP055373123 [A] 51-54 * . Especially pg 1112 col 1 para 2. *

DOI:   http://dx.doi.org/10.1038/ni1125
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.