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Extract from the Register of European Patents

EP About this file: EP3360573

EP3360573 - MEDICINAL DRUG FOR PREVENTING OR INHIBITING ACUTE KIDNEY INJURY [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  02.11.2018
Database last updated on 13.07.2024
FormerRequest for examination was made
Status updated on  13.07.2018
FormerThe international publication has been made
Status updated on  18.04.2017
Most recent event   Tooltip02.11.2018Withdrawal of applicationpublished on 05.12.2018  [2018/49]
Applicant(s)For all designated states
National Cerebral and Cardiovascular Center
5-7-1, Fujishirodai Suita-shi
Osaka 565-8565 / JP
[2018/33]
Inventor(s)01 / KANGAWA, Kenji
c/o NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
5-7-1 Fujishirodai
Suita-shi Osaka 565-8565 / JP
02 / HOSODA, Hiroshi
c/o NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
5-7-1 Fujishirodai
Suita-shi Osaka 565-8565 / JP
03 / NOJIRI, Takashi
c/o NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
5-7-1 Fujishirodai
Suita-shi Osaka 565-8565 / JP
 [2018/33]
Representative(s)Witte, Weller & Partner Patentanwälte mbB
Postfach 10 54 62
70047 Stuttgart / DE
[2018/33]
Application number, filing date16853615.905.10.2016
[2018/33]
WO2016JP79606
Priority number, dateJP2015019792105.10.2015         Original published format: JP 2015197921
JP2015025265924.12.2015         Original published format: JP 2015252659
[2018/33]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017061461
Date:13.04.2017
Language:JA
[2017/15]
Type: A1 Application with search report 
No.:EP3360573
Date:15.08.2018
Language:EN
[2018/33]
Search report(s)International search report - published on:JP13.04.2017
ClassificationIPC:A61K45/00, A61K31/18, A61K31/381, A61K31/44, A61K45/06, A61P13/12
[2018/33]
CPC:
A61K31/18 (EP,US); A61K31/34 (EP,US); A61K31/381 (EP,US);
A61K31/44 (EP,US); A61K45/00 (EP,US); A61K45/06 (EP,US);
A61P13/12 (EP,US); A61K2300/00 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/33]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:ARZNEIMITTEL ZUR VORBEUGUNG ODER HEMMUNG VON AKUTER NIERENLÄSION[2018/33]
English:MEDICINAL DRUG FOR PREVENTING OR INHIBITING ACUTE KIDNEY INJURY[2018/33]
French:MÉDICAMENT POUR PRÉVENIR OU INHIBER UNE INSUFFISANCE RÉNALE AIGUË[2018/33]
Entry into regional phase02.05.2018Translation filed 
02.05.2018National basic fee paid 
02.05.2018Search fee paid 
02.05.2018Designation fee(s) paid 
02.05.2018Examination fee paid 
Examination procedure02.05.2018Examination requested  [2018/33]
02.05.2018Date on which the examining division has become responsible
24.10.2018Application withdrawn by applicant  [2018/49]
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Cited inInternational search[XY]WO2008156142  (MITSUBISHI TANABE PHARMA CORP [JP], et al) [X] 12, 13 * , claims 1 to 16; paragraph [0040] & US 2010/0228026 A1 claims 1 to 16; paragraph [0070] & EP 2172450 A1 & KR 10-2010-0023967 A & CN 101784520 A * [Y] 4, 5;
 [PA]WO2015152393  (NAT CEREBRAL & CARDIOVASCULAR CT [JP], et al) [PA] 1-17 * , (Family: none) *
 [XY]  - MATAVELLI, L.C. et al., "Angiotensin AT 2 Receptor Stimulation Inhibits Early Renal Inflammation in Renovascular Hypertension", Hypertension, (20110000), vol. 57, no. 2, ISSN 0194-911X, pages 308 - 313, XP055080312 [X] 1, 10, 12-14, 16 * , particularly, Abstract, Figure 5 * [Y] 4, 5

DOI:   http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.164202
 [XY]  - HRENAK, J. et al., "Protective Effect of Captopril, Olmesartan, Melatonin and Compound 21 on Doxorubicin-Induced Nephrotoxicity in Rats", Physiol.Res., (20130000), ISSN 0862-8408, pages S181 - S189, XP055373844 [X] 12, 13 * , particularly, Summary, S186, right column, line 3 to S187, left column, line 11 * [Y] 1-11, 14-17
 [Y]  - OZKOK, A. et al., "Pathophysiology of Cisplatin- Induced Acute Kidney Injury", BioMed Research International, (20140000), vol. 2014, ISSN 2314-6133, pages 1 - 17, XP055373845 [Y] 1-11, 14-17 * , particularly, Table 2 *

DOI:   http://dx.doi.org/10.1155/2014/967826
 [X]  - ISHIGURO, S. et al., "Involvement of angiotensin II type 2 receptor ( AT 2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT 2R agonist effectively attenuates growth of PDAC grafts in mice", Cancer Biology & Therapy, (20150200), vol. 16, no. 2, ISSN 1538-4047, pages 307 - 316, XP055373847 [X] 6 * , particularly, Abstract, Figures 2-4 *

DOI:   http://dx.doi.org/10.1080/15384047.2014.1002357
 [A]  - DANYEL, L.A. et al., "Impact of AT 2-receptor stimulation on vascular biology, kidney function, and blood pressure", Integrated Blood Pressure Control, (20130000), vol. 6, doi:doi:10.2147/IBPC.S34425, ISSN 1178-7104, pages 153 - 161, XP055373851 [A] 1-17

DOI:   http://dx.doi.org/10.2147/IBPC.S34425
 [A]  - OKUI, S. et al., "Cisplatin-induced acute renal failure in mice is mediated by chymase- activated angiotensin-aldosterone system and interleukin-18", European Journal of Pharmacology, (20120000), vol. 685, pages 149 - 155, XP028489997 [A] 1-17

DOI:   http://dx.doi.org/10.1016/j.ejphar.2012.04.027
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