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Extract from the Register of European Patents

EP About this file: EP3368537

EP3368537 - PROCESS FOR PREPARING IBRUTINIB AND ITS INTERMEDIATES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  10.07.2020
Database last updated on 11.09.2024
FormerRequest for examination was made
Status updated on  03.08.2018
FormerThe international publication has been made
Status updated on  05.05.2017
Most recent event   Tooltip10.07.2020Application deemed to be withdrawnpublished on 12.08.2020  [2020/33]
Applicant(s)For all designated states
ScinoPharm Taiwan, Ltd.
No. 1, Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
[2018/36]
Inventor(s)01 / HSIAO, Tsung-Yu
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
02 / HO, Mengfen
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
03 / TSENG, Hsinchang
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
04 / TSAO, Wenshing
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
05 / HUANG, Yuanchang
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
06 / LO, Wei-Shuo
No. 1
Nan-Ke 8th Road
Southern Taiwan Science Park
Shan-Hua
Tainan 74144 / TW
 [2018/36]
Representative(s)Epping - Hermann - Fischer
Patentanwaltsgesellschaft mbH
Schloßschmidstraße 5
80639 München / DE
[2018/36]
Application number, filing date16860399.128.10.2016
[2018/36]
WO2016SG50528
Priority number, dateUS201562285035P28.10.2015         Original published format: US 201562285035 P
[2018/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017074265
Date:04.05.2017
Language:EN
[2017/18]
Type: A1 Application with search report 
No.:EP3368537
Date:05.09.2018
Language:EN
The application published by WIPO in one of the EPO official languages on 04.05.2017 takes the place of the publication of the European patent application.
[2018/36]
Search report(s)International search report - published on:KR04.05.2017
(Supplementary) European search report - dispatched on:EP20.05.2019
ClassificationIPC:C07D487/04, C07D401/04, A61K31/519, C07F9/6561
[2019/25]
CPC:
C07D487/04 (EP,KR,US); A61K31/519 (EP,KR,US); A61P35/02 (EP);
A61P43/00 (EP); C07D401/04 (KR,US); C07F9/6561 (US)
Former IPC [2018/36]C07D487/04, C07D401/04, A61K31/519
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/36]
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON IBRUTINIB UND SEINEN ZWISCHENPRODUKTEN[2018/36]
English:PROCESS FOR PREPARING IBRUTINIB AND ITS INTERMEDIATES[2018/36]
French:PROCÉDÉ DE PRÉPARATION D'IBRUTINIB ET DE SES INTERMÉDIAIRES[2018/36]
Entry into regional phase10.04.2018National basic fee paid 
10.04.2018Search fee paid 
10.04.2018Designation fee(s) paid 
10.04.2018Examination fee paid 
Examination procedure10.04.2018Examination requested  [2018/36]
10.04.2018Date on which the examining division has become responsible
21.10.2018Observations by third parties
06.12.2018Amendment by applicant (claims and/or description)
17.12.2019Application deemed to be withdrawn, date of legal effect  [2020/33]
27.01.2020Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2020/33]
Fees paidRenewal fee
12.03.2019Renewal fee patent year 03
15.10.2019Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.10.201803   M06   Fee paid on   12.03.2019
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Documents cited:Search[XPA]WO2016127915  (SHANGHAI DUDE MEDICAL SCIENCE AND TECH CO LTD [CN], et al) [XP] 1-5,16 * examples 17, 18 * [A] 6-15;
 [A]EP1780210  (KYORIN SEIYAKU KK [JP]) [A] 1-16 * reference example 10 *
International search[XYA]WO2015145415  (PERRIGO API LTD [IL]) [X] 26-29, 34-36 * See abstract; claims 59, 60, 82, 85; paragraph [00139]; figure 11. * [Y] 30-33 [A] 1-25;
 [A]CN104557945  (ARROMAX PHARMATECH CO LTD) [A] 1-36 * See the whole document. *;
 [A]CN103121999  (SUZHOU DEVI PHARMA TECHNOLOGY CO LTD) [A] 1-36 * See the whole document. *;
 [A]WO2015074464  (SUZHOU MIRACPHARMA TECHNOLOGY CO LTD [CN], et al) [A] 1-36 * See the whole document. *;
 [PX]WO2016115869  (HEFEI INST PHYSICAL SCI CAS [CN], et al) [PX] 24 * See page 25, compound 2. *
 [XYA]  - LIU, N. et al., "Direct and two-step bioorthogonal probes for Bruton' s tyrosine kinase based on ibrutinib: a comparative study", Organic & Biomolecular Chemistry, (20150327), vol. 13, no. 18, pages 5147 - 5157, XP055249951 [X] 1-13 * See abstract; page 5152, left column; scheme 1; figure 1. * [Y] 30-33 [A] 14-29, 34-36

DOI:   http://dx.doi.org/10.1039/C5OB00474H
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