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Extract from the Register of European Patents

EP About this file: EP3290428

EP3290428 - TABLET COMPRISING CRYSTALLINE (S)-ISOPROPYL 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1 (2H)-YL)-4-FLUORO-3-HYDROXY-4-METHYLTETRAHYDROFURAN-2-YL)METHOXY)(PHENOXY)PHOSPHORYL)AMINO)PROPANOATE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  19.08.2022
Database last updated on 02.11.2024
FormerThe patent has been granted
Status updated on  10.09.2021
FormerGrant of patent is intended
Status updated on  13.05.2021
FormerExamination is in progress
Status updated on  17.04.2020
FormerRequest for examination was made
Status updated on  07.09.2018
FormerThe application has been published
Status updated on  02.02.2018
Most recent event   Tooltip13.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 16.10.2024  [2024/42]
Applicant(s)For all designated states
Gilead Pharmasset LLC
c/o Gilead Sciences, Inc.
333 Lakeside Drive
Foster City, CA 94404 / US
[2018/10]
Inventor(s)01 / Ross, Bruce S
155 Del Monte Road
El Granada, CA California 94018 / US
02 / Sofia, Michael Joseph
3066 Antler Drive
Doylestown, PA Pennsylvania 18902 / US
03 / Pamulapati, Ganapati Reddy
1709 Blakesley Drive
San Ramon, CA California 94582 / US
04 / Rachakonda, Suguna
1272 Sharonbrook Drive
Twinsburg, OH Ohio 44087 / US
05 / Zhang, Hai-Ren
6767 Mason Way
San Jose, CA California 95129 / US
06 / Chun, Byoung-Kwon
135 Heritage Street
Robbinsville, NJ New Jersey 08691 / US
07 / Wang, Peiyuan
42 Continental Circle
Totowa, NJ New Jersey 07512 / US
 [2018/10]
Representative(s)Nieuwenhuys, William Francis
Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[2021/41]
Former [2018/10]Nieuwenhuys, William Francis
Marks & Clerk LLP 90 Long Acre London
WC2E 9RA / GB
Application number, filing date17172585.631.03.2011
[2018/10]
Priority number, dateUS20100319513P31.03.2010         Original published format: US 319513 P
US20100319548P31.03.2010         Original published format: US 319548 P
US2010078368020.05.2010         Original published format: US 783680
[2018/10]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3290428
Date:07.03.2018
Language:EN
[2018/10]
Type: B1 Patent specification 
No.:EP3290428
Date:13.10.2021
Language:EN
[2021/41]
Search report(s)(Supplementary) European search report - dispatched on:EP04.12.2017
ClassificationIPC:C07H19/10, C07H19/24, C07H19/207, C07H19/20, C07H19/06, C07H19/052, A61K31/7072, A61P31/14, C07H19/044, C07F9/22, C07H19/04, A61K31/664, A61K31/716, C07F7/18, C07F9/6558, C07F9/24, C07F9/655, C07F9/6561, A61P31/00
[2021/21]
CPC:
C07F9/65517 (EP); A61P31/00 (EP); A61P31/14 (EP);
C07F7/1804 (EP); C07F9/242 (EP); C07F9/2458 (EP);
C07F9/65586 (EP); C07F9/65616 (EP); C07H19/04 (EP);
C07H19/044 (EP); C07H19/052 (EP); C07H19/06 (EP);
C07H19/10 (EP); C07H19/20 (EP); C07H19/207 (EP);
C07H19/24 (EP) (-)
Former IPC [2018/10]C07H19/10, C07H19/073, A61K31/7072, A61P31/14, C07F9/22, A61K31/664, A61K31/716, C07F9/6558, C07F9/24
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2018/41]
Former [2018/10]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Extension statesBA04.09.2018
ME04.09.2018
TitleGerman:TABLETTE MIT KRYSTALLINEM (S)-ISOPROPYL 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1 (2H)-YL)-4-FLUORO-3-HYDROXY-4-METHYLTETRAHYDROFURAN-2-YL)METHOXY)(PHENOXY)PHOSPHORYL)AMINO)PROPANOAT[2018/10]
English:TABLET COMPRISING CRYSTALLINE (S)-ISOPROPYL 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1 (2H)-YL)-4-FLUORO-3-HYDROXY-4-METHYLTETRAHYDROFURAN-2-YL)METHOXY)(PHENOXY)PHOSPHORYL)AMINO)PROPANOATE[2018/10]
French:COMPRIMÉ CONTENANT CRISTALLIN (S)-ISOPROPYL 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1 (2H)-YL)-4-FLUORO-3-HYDROXY-4-METHYLTETRAHYDROFURAN-2-YL)METHOXY)(PHENOXY)PHOSPHORYL)AMINO)PROPANOATE[2018/10]
Examination procedure23.05.2017Date on which the examining division has become responsible
04.09.2018Amendment by applicant (claims and/or description)
04.09.2018Examination requested  [2018/41]
21.04.2020Despatch of a communication from the examining division (Time limit: M04)
28.08.2020Reply to a communication from the examining division
14.05.2021Communication of intention to grant the patent
02.09.2021Fee for grant paid
02.09.2021Fee for publishing/printing paid
02.09.2021Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP11714465.9  / EP2552930
EP13159791.6  / EP2609923
Opposition(s)14.07.2022No opposition filed within time limit [2022/38]
Fees paidRenewal fee
23.05.2017Renewal fee patent year 03
23.05.2017Renewal fee patent year 04
23.05.2017Renewal fee patent year 05
23.05.2017Renewal fee patent year 06
23.05.2017Renewal fee patent year 07
27.03.2018Renewal fee patent year 08
27.03.2019Renewal fee patent year 09
27.03.2020Renewal fee patent year 10
12.03.2021Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU31.03.2011
AL13.10.2021
CY13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
MK13.10.2021
MT13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
LU31.03.2022
[2024/42]
Former [2024/22]HU31.03.2011
AL13.10.2021
CY13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
MK13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
LU31.03.2022
Former [2024/20]HU31.03.2011
AL13.10.2021
CY13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
LU31.03.2022
Former [2024/18]HU31.03.2011
AL13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
LU31.03.2022
Former [2023/08]AL13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
LU31.03.2022
Former [2022/49]AL13.10.2021
DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/47]DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
MC13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/35]DK13.10.2021
EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/34]EE13.10.2021
FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
RO13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/33]FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
RS13.10.2021
SM13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/24]FI13.10.2021
HR13.10.2021
LT13.10.2021
LV13.10.2021
RS13.10.2021
BG13.01.2022
IS13.02.2022
Former [2022/22]FI13.10.2021
LT13.10.2021
RS13.10.2021
BG13.01.2022
Former [2022/21]RS13.10.2021
BG13.01.2022
Former [2022/19]BG13.01.2022
Documents cited:Search[AD]WO2008121634  (PHARMASSET INC [US], et al) [AD] 1-3 * claim 2; compound 25 *;
 [AP]WO2010135569  (PHARMASSET INC [US], et al) [AP] 1-3 * page 72 - page 76; example 21 *;
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.