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Extract from the Register of European Patents

EP About this file: EP3278813

EP3278813 - GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  16.08.2019
Database last updated on 02.11.2024
FormerRequest for examination was made
Status updated on  10.08.2018
FormerThe application has been published
Status updated on  05.01.2018
Most recent event   Tooltip26.06.2020Change - applicantpublished on 29.07.2020  [2020/31]
Applicant(s)For all designated states
Amunix Pharmaceuticals, Inc.
500 Ellis Street
Mountain View, CA 94043 / US
[2020/31]
Former [2019/11]For all designated states
Amunix Pharmaceuticals, Inc.
500 Ellis Street
Mountain View, c / US
Former [2018/06]For all designated states
Amunix Operating Inc.
500 Ellis Street
Mountain View, CA 94043 / US
Inventor(s)01 / SCHELLENBERGER, Volker
914 Moreno Avenue
Palo Alto, CA 94303 / US
02 / SILVERMAN, Joshua
27791 Edgerton Rd
Los Altos Hills, CA 94022 / US
03 / STEMMER, Willem P.
108 Kathy Court
Los Gatos, CA 95051 / US
04 / WANG, Chia-Wei
1449 David Lane
Milpitas, CA 95035 / US
05 / GEETHING, Nathan
9 Hemlock Lane
Acton, MA 01720 / US
06 / CLELAND, Jeffrey L.
225 Aberdeen Drive
San Carlos, CA 94070 / US
07 / SPINK, Benjamin
379 Northam Avenue
San Carlos, CA 94070 / US
 [2018/06]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2018/06]Kremer, Simon Mark
Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date17175282.708.06.2010
[2018/06]
Priority number, dateUS20090185112P08.06.2009         Original published format: US 185112 P
US20090236836P25.08.2009         Original published format: US 236836 P
US20090280955P10.11.2009         Original published format: US 280955 P
US2010069976103.02.2010         Original published format: US 699761
WO2010US2310603.02.2010         Original published format: PCT/US2010/023106
[2018/06]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3278813
Date:07.02.2018
Language:EN
[2018/06]
Search report(s)(Supplementary) European search report - dispatched on:EP08.11.2017
ClassificationIPC:A61K38/48, C07K14/46, C12N9/64, C07K14/61, C07H21/04, C12N15/63, C12N1/21, C12N5/10, A61P3/10, A61P3/04, A61P3/08, C12N15/62, A61K38/27, A61K9/00
[2018/06]
CPC:
C07K14/61 (EP,CN); A61P1/00 (EP); A61P1/04 (EP);
A61P15/00 (EP); A61P19/00 (EP); A61P19/02 (EP);
A61P19/08 (EP); A61P21/00 (EP); A61P21/04 (EP);
A61P25/00 (EP); A61P25/28 (EP); A61P3/00 (EP);
A61P3/04 (EP); A61P3/06 (EP); A61P3/08 (EP);
A61P3/10 (EP); A61P31/18 (EP); A61P5/06 (EP);
A61P5/22 (EP); A61P5/50 (EP); A61P7/04 (EP);
A61P9/10 (EP); A61P9/12 (EP); C07K14/00 (CN);
A61K38/00 (EP,CN); A61K9/0019 (EP); C07K2319/31 (EP);
C07K2319/35 (EP); C07K2319/50 (CN) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2018/37]
Former [2018/06]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:WACHSTUMSHORMONPOLYPEPTIDE SOWIE VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DAVON[2018/06]
English:GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME[2018/06]
French:POLYPEPTIDES DE L'HORMONE DE CROISSANCE ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION[2018/06]
Examination procedure09.06.2017Date on which the examining division has become responsible
01.08.2018Examination requested  [2018/37]
14.09.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
26.11.2018Amendment by applicant (claims and/or description)
08.08.2019Application withdrawn by applicant  [2019/38]
Parent application(s)   TooltipEP10786725.1  / EP2440241
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
26.11.2018Request for further processing filed
26.11.2018Full payment received (date of receipt of payment)
Request granted
07.12.2018Decision despatched
Fees paidRenewal fee
28.06.2017Renewal fee patent year 03
28.06.2017Renewal fee patent year 04
28.06.2017Renewal fee patent year 05
28.06.2017Renewal fee patent year 06
28.06.2017Renewal fee patent year 07
28.06.2017Renewal fee patent year 08
27.06.2018Renewal fee patent year 09
27.06.2019Renewal fee patent year 10
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]WO2007103515  (AMUNIX INC [US], et al) [I] 1-19 * figure 44; claim - * * page 2 - page 3 * * page 71, paragraph [00261] *;
 [A]WO2008155134  (UNIV MUENCHEN TECH [DE], et al) [A] 1-19 * the whole document *;
 [E]WO2010091122  (AMUNIX INC [US], et al) [E] 1-19 * claim -; sequences 1812, 1813, 1817, 1818 * * page 173 - page 177; examples 32-40 * * figures 29-34 ** page 440 - page 442; table 44 *;
 [A]  - PAULA ALVAREZ ET AL, "Improving protein pharmacokinetics by genetic fusion to simple amino acid sequences", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (200401), vol. 279, doi:10.1074/JBC.M311356200, ISSN 0021-9258, pages 3375 - 3380, XP008131025 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.M311356200
 [T]  - CLELAND JEFFREY L ET AL, "A novel long-acting human growth hormone fusion protein (vrs-317): enhanced in vivo potency and half-life", JOURNAL OF PHARMACEUTICAL SCIENCES, (20120607), vol. 101, no. 8, pages 2744 - 2754, XP002694804 [T] * the whole document *

DOI:   http://dx.doi.org/10.1002/JPS.23229
 [A]  - M. SCHLAPSCHY ET AL, "Fusion of a recombinanat antibody fragment with a homo-amino -acid polymer: effects on biophysical properties and prolonged plasma half-life", PROTEIN ENGINEERING, DESIGN & SELECTION, oxford journal london, GB, (20070626), vol. 20, no. 6, pages 273 - 284, XP002498446 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1093/protein/gzm020
 [XP]  - CLELAND JEFFREY L ET AL, "A novel human growth hormone XTEN construct (VRS-317) for monthly administration", ENDOCRINE JOURNAL, & 14TH INTERNATIONAL CONGRESS OF ENDOCRINOLOGY ICE2010; KYOTO, JAPAN; MARCH 26 -30, 2010, (201003), vol. 57, no. Suppl. 2, ISSN 0918-8959, page S618, XP002696184 [XP] 1-19 * abstract *
 [XP]  - VOLKER SCHELLENBERGER ET AL, "A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner", NATURE BIOTECHNOLOGY, GALE GROUP INC, vol. 27, no. 12, doi:10.1038/NBT.1588, ISSN 1087-0156, (20091115), pages 1186 - 1190, (20091115), XP002665891 [XP] 1-19 * page 1188; table 1 * * page 1189, column l, paragraph 1 *

DOI:   http://dx.doi.org/10.1038/NBT.1588
 [XP]  - VOLKER SCHELLENBERGER ET AL, "Online Supplementary Material: A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner", NATURE BIOTECHNOLOGY, (20091115), vol. 27, no. 12, doi:10.1038/nbt.1588, ISSN 1087-0156, pages 1186 - 1190, XP055190665 [XP] 1-19 * page 15 - page 18; figure S7 *

DOI:   http://dx.doi.org/10.1038/nbt.1588
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.