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EP3272353
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EP About this file: EP3272353
| EP3272353 - METHODS FOR PREVENTING OR TREATING INSULIN RESISTANCE [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 14.12.2018 Database last updated on 28.03.2026 | |
| Former | The application has been published Status updated on 28.12.2017 | Most recent event Tooltip | 14.12.2018 | Application deemed to be withdrawn | published on 16.01.2019 [2019/03] | Applicant(s) | For all designated states Cornell University Cornell Center for Technology Enterprise And Commercialization (CCTEC) 395 Pine Tree Road Suite 310 Ithaca, NY 14850 / US | For all designated states East Carolina University 210 Spilman Building Greenville, NC 27858 / US | [2018/04] | Inventor(s) | 01 /
NEUFER, P. Darrell 3703 Tucker Drive Greenville, NC North Carolina 27858 / US | 02 /
ANDERSON, Ethan J. 657 Cedar Ridge Dr. Winterville, NC North Carolina 28590 / US | 03 /
SZETO, Hazel H. 50 East 89th Street Apartment 25A New York, NY New York 10128 / US | [2018/04] | Representative(s) | J A Kemp LLP 80 Turnmill Street London EC1M 5QU / GB | [N/P] |
| Former [2018/04] | J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | Application number, filing date | 17175315.5 | 06.02.2009 | [2018/04] | Priority number, date | US20080026882P | 07.02.2008 Original published format: US 26882 P | [2018/04] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3272353 | Date: | 24.01.2018 | Language: | EN | [2018/04] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 18.10.2017 | Classification | IPC: | A61K38/00 | [2018/04] | CPC: |
A61K38/07 (EP,US);
A61K38/06 (EP,US);
A61P1/16 (EP);
A61P13/12 (EP);
A61P29/00 (EP);
A61P3/04 (EP);
A61P3/06 (EP);
A61P3/08 (EP);
A61P3/10 (EP);
A61P43/00 (EP);
A61P5/50 (EP);
A61P9/00 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2018/04] | Title | German: | VERFAHREN ZUR VORBEUGUNG ODER BEHANDLUNG VON INSULINRESISTENZ | [2018/04] | English: | METHODS FOR PREVENTING OR TREATING INSULIN RESISTANCE | [2018/04] | French: | PROCÉDÉS DE PRÉVENTION OU DE TRAITEMENT DE LA RÉSISTANCE À L'INSULINE | [2018/04] | Examination procedure | 25.07.2018 | Application deemed to be withdrawn, date of legal effect [2019/03] | 30.08.2018 | Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time [2019/03] | Parent application(s) Tooltip | EP09707235.9 / EP2252312 | EP13196962.8 / EP2712620 | EP14186864.6 / EP2902036 | EP16154315.2 / EP3103467 | Divisional application(s) | EP18184266.7 / EP3441079 | EP19191291.4 / EP3622963 | Fees paid | Renewal fee | 09.06.2017 | Renewal fee patent year 03 | 09.06.2017 | Renewal fee patent year 04 | 09.06.2017 | Renewal fee patent year 05 | 09.06.2017 | Renewal fee patent year 06 | 09.06.2017 | Renewal fee patent year 07 | 09.06.2017 | Renewal fee patent year 08 | 09.06.2017 | Renewal fee patent year 09 | 14.02.2018 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A] US2007129306 (SZETO HAZEL H et al.) | [A] US2007259377 (URDEA MICKEY et al.) | [XP] ANDERSON ETHAN J ET AL: "Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.", THE JOURNAL OF CLINICAL INVESTIGATION MAR 2009 LNKD- DOI:10.1172/JCI37048 PUBMED:19188683, vol. 119, no. 3, 2 February 2009 (2009-02-02), pages 573 - 581, XP002638673, ISSN: 1558-8238 DOI: http://dx.doi.org/10.1172/JCI37048 | [A] THOMAS DOLCA A ET AL: "Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol. 18, no. 1, January 2007 (2007-01-01), pages 213 - 222, XP002638674, ISSN: 1046-6673 DOI: http://dx.doi.org/10.1681/ASN.2006080825 | [A] LOWELL BRADFORD B ET AL: "Mitochondrial dysfunction and type 2 diabetes.", SCIENCE (NEW YORK, N.Y.) 21 JAN 2005 LNKD- PUBMED:15662004, vol. 307, no. 5708, 21 January 2005 (2005-01-21), pages 384 - 387, XP002638675, ISSN: 1095-9203 | [A] MORINO KATSUTARO ET AL: "Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction", DIABETES, vol. 55, no. Suppl. 2, December 2006 (2006-12-01), pages S9 - S15, XP002638676, ISSN: 0012-1797 DOI: http://dx.doi.org/10.2337/db06-S002 | [A] SHEU S S ET AL: "Targeting antioxidants to mitochondria: A new therapeutic direction", BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, AMSTERDAM, NL, vol. 1762, no. 2, 1 February 2006 (2006-02-01), pages 256 - 265, XP025138836, ISSN: 0925-4439, [retrieved on 20060201], DOI: 10.1016/J.BBADIS.2005.10.007 DOI: http://dx.doi.org/10.1016/j.bbadis.2005.10.007 | [A] SZETO HAZEL H: "Cell-permeable, mitochondrial-targeted, peptide antioxidants", AAPS JOURNAL, AMERICAN ASSOCIATION OF PHARMACEUTICAL SCIENTISTS, US, vol. 8, no. 2, 21 April 2006 (2006-04-21), pages E277 - E283, XP002594481, ISSN: 1550-7416 | [A] CHO SUNGHEE ET AL: "A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 16 FEB 2007 LNKD- PUBMED:17178711, vol. 282, no. 7, 16 February 2007 (2007-02-16), pages 4634 - 4642, XP002638723, ISSN: 0021-9258 DOI: http://dx.doi.org/10.1074/JBC.M609388200 | [A] THOMAS D ET AL: "Abstract 2842: Increased islet yield and reduced apoptosis by prevention of mitochondrial depolarization with cell permeable peptide D-ARG-DMT-LYS-PHE-NH2", AMERICAN JOURNAL OF TRANSPLANTATION; WORLD TRANSPLANT CONGRESS 2006 : 21ST INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY, BLACKWELL MUNKSGAARD, DK; HYNES CONVENTION CENTER, BOSTON MASSACHUSETTS, USA, vol. 6, no. S2, 1 August 2006 (2006-08-01), pages 991 - 992, XP008145670, ISSN: 1600-6135, [retrieved on 20060811], DOI: 10.1111/J.1600-6143.2006.01447.X DOI: http://dx.doi.org/10.1111/j.1600-6143.2006.01447.x | [A] UNGER R H ET AL: "Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes", DIABETOLOGIA, SPRINGER, BERLIN, DE, vol. 28, no. 3, 1 March 1985 (1985-03-01), pages 119 - 121, XP009148794, ISSN: 0012-186X | [A] ZHAO K ET AL: "Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 279, no. 33, 13 August 2004 (2004-08-13), pages 34682 - 34690, XP002594478, ISSN: 0021-9258, [retrieved on 20040602], DOI: 10.1074/JBC.M402999200 DOI: http://dx.doi.org/10.1074/JBC.M402999200 | [A] CORPELEIJN E ET AL: "Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance.", August 2006, DIABETIC MEDICINE : A JOURNAL OF THE BRITISH DIABETIC ASSOCIATION AUG 2006, VOL. 23, NR. 8, PAGE(S) 907 - 911, ISSN: 0742-3071, XP002719997 DOI: http://dx.doi.org/10.1111/j.1464-5491.2006.01888.x | [A] AITMAN T J ET AL: "IDENTIFICATION OF CD36 (FAT) AS AN INSULIN-RESISTANCE GENE CAUSING DEFECTIVE FATTY ACID AND GLUCOSE METABOLISM IN HYPERTENSIVE RATS", NATURE GENETICS, NATURE PUBLISHING GROUP, NEW YORK, US, vol. 21, no. 1, 1 January 1999 (1999-01-01), pages 76 - 83, XP001002349, ISSN: 1061-4036, DOI: 10.1038/5013 DOI: http://dx.doi.org/10.1038/5013 | by applicant | US6468798 | WO9915154 | US5674534 | US5716644 | WO9640073 | WO0038651 | US4522811 | US3817837 | US3850752 | US3939350 | US3996345 | US4277437 | US4275149 | US4366241 | US4391904 | "Current Protocols in Molecular Biology", vol. 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