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EP About this file: EP3309253

EP3309253 - GENES FOR BIOSYNTHESIS OF TETRACYCLINE COMPOUNDS AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.08.2021
Database last updated on 03.10.2024
FormerThe patent has been granted
Status updated on  11.09.2020
FormerGrant of patent is intended
Status updated on  02.07.2020
FormerExamination is in progress
Status updated on  14.09.2019
FormerRequest for examination was made
Status updated on  02.11.2018
FormerThe application has been published
Status updated on  22.03.2018
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT
published on 09.10.2024 [2024/41]
Applicant(s)For all designated states
Univerza v Ljubljani
Kongresni trg 12
1000 Ljubljana / SI
[2018/16]
Inventor(s)01 / PETKOVIC, Hrvoje
Ulica bratov Ucakar 36
1000 Ljubljana / SI
02 / RASPOR, Peter
Neubergerjeva 13
1000 Ljubljana / SI
03 / LESNIK, Urska
Ulica Zore Majcenove 4
1000 Ljubljana / SI
 [2018/16]
Representative(s)Zacco GmbH
Bayerstrasse 83
80335 München / DE
[2018/16]
Application number, filing date17194792.207.08.2009
[2018/16]
Priority number, dateEP2008001414107.08.2008         Original published format: EP 08014141
[2018/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3309253
Date:18.04.2018
Language:EN
[2018/16]
Type: B1 Patent specification 
No.:EP3309253
Date:14.10.2020
Language:EN
[2020/42]
Search report(s)(Supplementary) European search report - dispatched on:EP05.03.2018
ClassificationIPC:C12N15/31, C07K14/195, C07C237/26
[2018/16]
CPC:
C07C237/26 (EP,US); A61P19/10 (EP); A61P25/16 (EP);
A61P25/28 (EP); A61P31/04 (EP); A61P31/10 (EP);
A61P35/00 (EP); A61P37/00 (EP); C07C225/20 (EP,US);
C07C49/747 (EP,US); C07K14/36 (EP,US); C07C2603/46 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2018/49]
Former [2018/16]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  SM,  TR 
TitleGerman:GENE FÜR DIE BIOSYNTHESE VON TETRACYCLIN-VERBINDUNGEN UND VERWENDUNGEN DAVON[2018/16]
English:GENES FOR BIOSYNTHESIS OF TETRACYCLINE COMPOUNDS AND USES THEREOF[2018/16]
French:GÈNES POUR LA BIOSYNTHÈSE DE COMPOSÉS DE TÉTRACYCLINE ET LEURS UTILISATIONS[2018/16]
Examination procedure18.10.2018Amendment by applicant (claims and/or description)
18.10.2018Examination requested  [2018/49]
18.10.2018Date on which the examining division has become responsible
18.09.2019Despatch of a communication from the examining division (Time limit: M04)
15.01.2020Reply to a communication from the examining division
03.07.2020Communication of intention to grant the patent
08.09.2020Fee for grant paid
08.09.2020Fee for publishing/printing paid
08.09.2020Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP09010246.8  / EP2154150
Opposition(s)15.07.2021No opposition filed within time limit [2021/38]
Fees paidRenewal fee
04.10.2017Renewal fee patent year 03
04.10.2017Renewal fee patent year 04
04.10.2017Renewal fee patent year 05
04.10.2017Renewal fee patent year 06
04.10.2017Renewal fee patent year 07
04.10.2017Renewal fee patent year 08
04.10.2017Renewal fee patent year 09
31.07.2018Renewal fee patent year 10
19.08.2019Renewal fee patent year 11
14.07.2020Renewal fee patent year 12
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Lapses during opposition  TooltipHU07.08.2009
AT14.10.2020
CY14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
MC14.10.2020
MK14.10.2020
MT14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
[2024/41]
Former [2024/22]HU07.08.2009
AT14.10.2020
CY14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
MC14.10.2020
MK14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2023/29]HU07.08.2009
AT14.10.2020
CY14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
MC14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2023/24]AT14.10.2020
CY14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
MC14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2022/18]AT14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
MC14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2021/48]AT14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
IT14.10.2020
LT14.10.2020
LV14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2021/37]AT14.10.2020
CZ14.10.2020
DK14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
LT14.10.2020
LV14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2021/36]AT14.10.2020
CZ14.10.2020
EE14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
LT14.10.2020
LV14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2021/35]AT14.10.2020
CZ14.10.2020
ES14.10.2020
FI14.10.2020
HR14.10.2020
LT14.10.2020
LV14.10.2020
NL14.10.2020
PL14.10.2020
RO14.10.2020
SE14.10.2020
SK14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
PT15.02.2021
Former [2021/34]AT14.10.2020
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FI14.10.2020
HR14.10.2020
LT14.10.2020
LV14.10.2020
NL14.10.2020
PL14.10.2020
SE14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
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SE14.10.2020
SM14.10.2020
BG14.01.2021
NO14.01.2021
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IS14.02.2021
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SM14.10.2020
BG14.01.2021
NO14.01.2021
GR15.01.2021
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BG14.01.2021
NO14.01.2021
GR15.01.2021
IS14.02.2021
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NO14.01.2021
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IS14.02.2021
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Former [2021/25]AT14.10.2020
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SE14.10.2020
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GR15.01.2021
IS14.02.2021
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Former [2021/23]AT14.10.2020
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Former [2021/22]FI14.10.2020
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Former [2021/20]FI14.10.2020
Documents cited:Search[XI]US3824285  (BLACKWOOD R, et al) [X] 1 * structure IX; columns 3-4 * * column 2, line 32 - line 35 * [I] 2;
 [XI]  - I CHOPRA, "Tetracycline analogs whose primary target is not the bacterial ribosome", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, (19940401), vol. 38, no. 4, ISSN 0066-4804, pages 637 - 640, XP055452259 [X] 1 * the whole document * [I] 3-5
 [A]  - ZAKERI BIJAN ET AL, "Chemical biology of tetracycline antibiotics", BIOCHEMISTRY AND CELL BIOLOGY, (200804), vol. 86, no. 2, ISSN 0829-8211, pages 124 - 136, XP002500431 [A] 1-9 * page 127, column r, paragraph l - page 129, column l, paragraph 1 *

DOI:   http://dx.doi.org/10.1139/O08-002
 [A]  - ZHANG WENJUN ET AL, "Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (200604), vol. 72, no. 4, ISSN 0099-2240, pages 2573 - 2580, XP002500434 [A] 1-9 * see the whole document *

DOI:   http://dx.doi.org/10.1128/AEM.72.4.2573-2580.2006
 [A]  - ZHANG WENJUN ET AL, "Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway", JOURNAL OF BIOLOGICAL CHEMISTRY, (200708), vol. 282, no. 35, ISSN 0021-9258, pages 25717 - 25725, XP002500433 [A] 1-9 * see the whole document *

DOI:   http://dx.doi.org/10.1074/JBC.M703437200
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