EP3447153 - METHOD FOR DETERMINING THE QUALIFICATION OF A SAMPLE FOR FETAL ANEUPLOIDY STATUS DETERMINATION IN NON-INVASIVE PRENATAL TESTING [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 02.09.2022 Database last updated on 02.11.2024 | |
Former | The patent has been granted Status updated on 24.09.2021 | ||
Former | Grant of patent is intended Status updated on 10.05.2021 | ||
Former | Examination is in progress Status updated on 10.09.2020 | ||
Former | Request for examination was made Status updated on 21.06.2019 | ||
Former | The application has been published Status updated on 25.01.2019 | Most recent event Tooltip | 13.09.2024 | Lapse of the patent in a contracting state New state(s): MT | published on 16.10.2024 [2024/42] | Applicant(s) | For all designated states Comenius University in Bratislava Safárikovo námestie 6 814 99 Bratislava 1 / SK | [2021/22] |
Former [2019/09] | For all designated states Grendár, Marian Spojová 10 97404 Banská Bystrica / SI | ||
For all designated states Loderer, Dusan Pod Dubinkou 256 97662 Brusno / SK | |||
For all designated states Lasabová, Zora A. Mednanského 4972/22 03608 Martin / SK | |||
For all designated states Danko, Ján Hrdinov SNP 88 03601 Martin / SK | Inventor(s) | 01 /
Grendár, Marian Spojová 10 97404 Banská Bystrica / SK | 02 /
Loderer, Dusan Pod Dubinkou 256 97662 Brusno / SK | 03 /
Lasabová, Zora A. Mednanského 4972/22 03608 Martin / SK | 04 /
Danko, Ján Hrdinov SNP 88 03601 Martin / SK | [2021/42] |
Former [2021/12] | 01 /
Grendár, Marian Spojová 10 97404 Banská Bystrica / SI | ||
02 /
Loderer, Dusan Pod Dubinkou 256 97662 Brusno / SK | |||
03 /
Lasabová, Zora A. Mednanského 4972/22 03608 Martin / SK | |||
04 /
Danko, Ján Hrdinov SNP 88 03601 Martin / SK | |||
Former [2019/09] | 01 /
see applicant ... | Representative(s) | Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB Ganghoferstraße 68 B 80339 München / DE | [2019/09] | Application number, filing date | 17203198.1 | 23.11.2017 | [2019/09] | Priority number, date | SK20170000086 | 24.08.2017 Original published format: SK 862017 | [2019/09] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3447153 | Date: | 27.02.2019 | Language: | EN | [2019/09] | Type: | B1 Patent specification | No.: | EP3447153 | Date: | 27.10.2021 | Language: | EN | [2021/43] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 22.05.2018 | Classification | IPC: | C12Q1/6806 | [2019/09] | CPC: |
C12Q1/6806 (EP)
| C-Set: |
C12Q1/6806, C12Q2537/165, C12Q2543/101 (EP)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/30] |
Former [2019/09] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | VERFAHREN ZUR BESTIMMUNG DER EIGNUNG EINER PROBE ZUR BESTIMMUNG DES STATUS VON FÖTALER ANEUPLOIDIE IN NICHTINVASIVEN PRÄNATALEN TESTS | [2019/09] | English: | METHOD FOR DETERMINING THE QUALIFICATION OF A SAMPLE FOR FETAL ANEUPLOIDY STATUS DETERMINATION IN NON-INVASIVE PRENATAL TESTING | [2019/09] | French: | PROCÉDÉ POUR DÉTERMINER LA QUALIFICATION D'UN ÉCHANTILLON DE DÉTERMINATION DE L'ÉTAT D'ANEUPLOÏDIE F TALE LORS D'ESSAIS PRÉNATAUX NON INVASIFS | [2019/09] | Examination procedure | 12.06.2019 | Amendment by applicant (claims and/or description) | 12.06.2019 | Examination requested [2019/30] | 12.06.2019 | Date on which the examining division has become responsible | 09.09.2020 | Despatch of a communication from the examining division (Time limit: M04) | 08.12.2020 | Reply to a communication from the examining division | 11.05.2021 | Communication of intention to grant the patent | 15.09.2021 | Receipt of the translation of the claim(s) | 20.09.2021 | Fee for grant paid | 20.09.2021 | Fee for publishing/printing paid | Opposition(s) | 28.07.2022 | No opposition filed within time limit [2022/40] | Fees paid | Renewal fee | 26.11.2019 | Renewal fee patent year 03 | 20.11.2020 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 23.11.2017 | AL | 27.10.2021 | AT | 27.10.2021 | CY | 27.10.2021 | CZ | 27.10.2021 | DK | 27.10.2021 | EE | 27.10.2021 | ES | 27.10.2021 | FI | 27.10.2021 | HR | 27.10.2021 | IT | 27.10.2021 | LT | 27.10.2021 | LV | 27.10.2021 | MC | 27.10.2021 | MK | 27.10.2021 | MT | 27.10.2021 | NL | 27.10.2021 | PL | 27.10.2021 | RO | 27.10.2021 | RS | 27.10.2021 | SE | 27.10.2021 | SI | 27.10.2021 | SM | 27.10.2021 | TR | 27.10.2021 | IE | 23.11.2021 | LU | 23.11.2021 | BE | 30.11.2021 | CH | 30.11.2021 | LI | 30.11.2021 | FR | 27.12.2021 | BG | 27.01.2022 | GB | 27.01.2022 | NO | 27.01.2022 | GR | 28.01.2022 | IS | 27.02.2022 | PT | 28.02.2022 | DE | 01.06.2022 | [2024/42] |
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Former [2022/19] | BG | 27.01.2022 | Documents cited: | Search | [I]WO2016057901 (SEQUENOM INC [US]) [I] 1-15 * example 1 *; | [I] - DAPHNE M. VAN BEEK ET AL, "Comparing methods for fetal fraction determination and quality control of NIPT samples : Comparing fetal fraction and quality control tools for NIPT", PRENATAL DIAGNOSIS, GB, (20170710), vol. 37, no. 8, doi:10.1002/pd.5079, ISSN 0197-3851, pages 769 - 773, XP055472942 [I] 1-15 * the whole document * DOI: http://dx.doi.org/10.1002/pd.5079 | [I] - FRANCESCO FIORENTINO ET AL, "The importance of determining the limit of detection of non-invasive prenatal testing methods : The importance of determining the limit of detection of NIPT methods", PRENATAL DIAGNOSIS, GB, (20160221), vol. 36, no. 4, doi:10.1002/pd.4780, ISSN 0197-3851, pages 304 - 311, XP055473015 [I] 1-15 * page 308 * DOI: http://dx.doi.org/10.1002/pd.4780 | [I] - C. ZHAO ET AL, "Detection of Fetal Subchromosomal Abnormalities by Sequencing Circulating Cell-Free DNA from Maternal Plasma", CLINICAL CHEMISTRY, (20150220), vol. 61, no. 4, doi:10.1373/clinchem.2014.233312, ISSN 0009-9147, pages 608 - 616, XP055215005 [I] 1-15 * page 610 * DOI: http://dx.doi.org/10.1373/clinchem.2014.233312 | [I] - MARKUS STUMM ET AL, "Diagnostic accuracy of random massively parallel sequencing for non-invasive prenatal detection of common autosomal aneuploidies: a collaborative study in Europe", PRENATAL DIAGNOSIS, GB, (20131212), vol. 34, no. 2, doi:10.1002/pd.4278, ISSN 0197-3851, pages 185 - 191, XP055344715 [I] 1-15 * page 187 * DOI: http://dx.doi.org/10.1002/pd.4278 | [I] - L. F. JOHANSSON ET AL, "Novel Algorithms for Improved Sensitivity in Non-Invasive Prenatal Testing", SCIENTIFIC REPORTS, (20170512), vol. 7, no. 1, doi:10.1038/s41598-017-02031-5, XP055472801 [I] 1-15 * page 2 * DOI: http://dx.doi.org/10.1038/s41598-017-02031-5 | [I] - HAN ZHANG ET AL, "Statistical Approach to Decreasing the Error Rate of Noninvasive Prenatal Aneuploid Detection caused by Maternal Copy Number Variation", SCIENTIFIC REPORTS, (20151104), vol. 5, no. 1, doi:10.1038/srep16106, pages 1 - 9, XP055407852 [I] 1-15 * the whole document * DOI: http://dx.doi.org/10.1038/srep16106 | [A] - TANJA SCHLAIKJAER HARTWIG ET AL, "Discordant non-invasive prenatal testing (NIPT) - a systematic review : Discordant NIPT cases - a review", PRENATAL DIAGNOSIS, GB, (20170601), vol. 37, no. 6, doi:10.1002/pd.5049, ISSN 0197-3851, pages 527 - 539, XP055472773 [A] 1 * the whole document * DOI: http://dx.doi.org/10.1002/pd.5049 | [A] - C. H. YEANG ET AL, "Genome-wide normalized score: a novel algorithm to detect fetal trisomy 21 during non-invasive prenatal testing", ULTRASOUND IN OBSTETRICS AND GYNECOLOGY, GB, (20140612), vol. 44, no. 1, doi:10.1002/uog.13377, ISSN 0960-7692, pages 25 - 30, XP055407854 [A] 1 * the whole document * DOI: http://dx.doi.org/10.1002/uog.13377 | by applicant | WO9844151 | EP0994963 | WO2006084132 | EP1981995 | EP2183693 | EP2514842 | EP2981921 | US2016224724 | WO2017050244 | - LO et al., The Lancet, (19970000), vol. 350, pages 485 - 487 | - BAYINDIR et al., Eur. J. Hum. Genet., (20150000), vol. 23, pages 1286 - 1293 | - PORRECO et al., Am. J. Obstet. Gynecol., (20140000), vol. 211, pages 365 - e1 | - THUNG et al., Expert. Rev. Mol. Diagn., (20150000), vol. 15, pages 111 - 124 | - TAMMINGA et al., Adv. Clin. Chem., (20160000), vol. 74, pages 63 - 102 | - CHIU et al., Proc. Natl. Acad. Sci., (20080000), vol. 105, pages 20458 - 20463 | - JENSEN et al., PloS One, (20130000), vol. 8, page e57381 | - CHANDRANANDA et al., PloS One, (20140000), vol. 9, page e86993 | - SEHNERT et al., Clin. Chem., (20110000), vol. 57, pages 1042 - 1049 | - ZHAO et al., Clin. Chem., (20150000), vol. 61, pages 608 - 616 | - YEANG et al., Ultrasound Obstet. & Gynecol., (20140000), vol. 44, pages 25 - 30 | - JOHANSSON et al., Sci. Reports, (20170000), vol. 7 | - SIKKEMA-RADDATZ et al., Sci. Reports, (20160000), vol. 6, page 38359 | - BALSLEV-HARDER et al., Prenat. Diagn. | - PALOMAKI et al., Genet. Medicine, (20110000), vol. 13, pages 913 - 920 | - CANICK et al., Prenat. Diagn., (20130000), vol. 33, pages 667 - 674 | - EHRICH et al., Am. J. Obstet. Gynecol., (20110000), vol. 204, pages 205 - e1 | - NORTON et al., Am. J. Obstet. Gynecol., (20120000), vol. 207, pages 137 - e1 | - ASHOOR et al., Ultrasound Obstet. & Gynecol., (20130000), vol. 41, pages 26 - 32 | - FIORENTINO et al., Prenat. Diagn., (20160000), vol. 36, pages 304 - 311 | - MACKIE et al., BJOG: An Int. J. Obstet. & Gynaecol., (20170000), vol. 124, pages 32 - 46 | - GIL et al., Fetal Diagn. Ther., (20140000), vol. 35, pages 156 - 173 | - TAYLOR-PHILLIPS et al., BMJ Open, (20160000), vol. 6, page e010002 | - TAMMINGA et al., Advances in clinical chemistry, (20160000), vol. 74, pages 63 - 102 | - NORWITZ et al., Rev Obstet Gynecol, (20130000), vol. 6, no. 2, pages 48 - 62 | - BARRETT et al., PloS One, (20110000), vol. 6, page e25202 | - FIORENTINO et al., Prenat. Diagn., vol. 36, (20160000), pages 304 - 311, URL: http://dx.doi.org/10.1002/pd.4780 | - KIM et al., Prenat. Diagn., (20150000), vol. 35, pages 810 - 815 | - LO, Open Biol., (20120000), vol. 2, no. 6 | - NIGAM et al., JIMSA, (20120000), vol. 25, pages 119 - 200 | - CHIU, BMJ, (20110000), vol. 342, page c7401 | - HUDECOVA et al., PLoS One, (20140000), vol. 9, page e88484 | - LIAO et al., Clin Chem, (20110000), vol. 57, pages 91 - 101 | - LO et al., Sci Transl Med, (20100000), vol. 2, page 61ra91 | - YU et al., PNAS, (20140000), vol. 111, pages 8583 - 8588 | - LANGMEAD et al., Nat Methods, (20120000), vol. 9, pages 357 - 359 | - VOELKERDING et al., Clin Chem, (20090000), vol. 55, no. 4, pages 641 - 658 | - WHEELER et al., Nature, (20080000), vol. 452, no. 7189, pages 872 - 876 | - CANARD et al., Gene, (19940000), vol. 148, no. 1, pages 1 - 6 | - FENG et al., Mol Ecol Res, (20150000), vol. 16, no. 1, pages 91 - 102 | - SCHUSTER, Nat Methods, (20080000), vol. 51, no. 1, pages 16 - 18 | - DRMANAC et al., Science, (20100000), vol. 327, no. 5961, pages 78 - 81 | - PORRECA, Nat Biotechnol, (20100000), vol. 28, no. 1, pages 43 - 44 | - HARRIS et al., Science, (20080000), vol. 320, no. 5872, pages 106 - 109 | - LEVENE et al., Science, (20030000), vol. 299, no. 5607, pages 982 - 686 | - EID et al., Science, (20090000), vol. 323, no. 5910, pages 133 - 138 | - NIEDRINGHAUS et al., Anal Chem, (20110000), vol. 83, no. 12, pages 4327 - 4341 | - GREININGER et al., Genome Medicine, (20150000), vol. 7, page 99 | - LANGMEAD et al., Nat. Methods, (20120000), vol. 9, pages 357 - 359 | - HUBER et al., Nat. Methods, vol. 12, (20150000), pages 115 - 121, URL: http://dx.doi.org/10.1038/nmeth.3252. DOI 10.1038/nmeth.3252 | - HUDECOVA et al., PloS One, (20140000), vol. 9, page e88484 | - CHIU et al., BMJ, (20110000), vol. 342, page c7401 | - VAN BEEK et al., Prenat. Diagn., (20170000), vol. 37, pages 769 - 773 | - PENG et al., Int. J. Mol. Sci., (20170000), vol. 18, page 453 | - "R Core Team. R: A Language and Environment for Statistical Computing", R Foundation for Statistical Computing, (20150000), URL: https://www.R-project.org |