| Designated contracting states | AL | | AT | | BE | | BG | | CH | | CY | | CZ | | DE | | DK | | EE | | ES | | FI | | FR | | GB | | GR | | HR | | HU | | IE | | IS | | IT | | LI | | LT | | LU | | LV | | MC | | MK | | MT | | NL | | NO | | PL | | PT | | RO | | RS | | SE | | SI | | SK | | SM | | TR | | Validation states | MA | | MD | | Examination procedure | 25.03.2022 | Receipt of the translation of the claim(s) | Entry into regional phase | 27.09.2018 | National basic fee paid | | 27.09.2018 | Designation fee(s) paid | | 27.09.2018 | Examination fee paid | | Fees paid | Renewal fee | 27.03.2019 | Renewal fee patent year 03 | 23.03.2020 | Renewal fee patent year 04 | 27.04.2021 | Renewal fee patent year 05 | 21.04.2022 | Renewal fee patent year 06 | European patent granted | 01.06.2022 | Opposition procedure | 14.04.2025 | Despatch of communication that the patent will be maintained as amended | | Appeal following opposition | 05.02.2025 | APPEAL FILED | 05.02.2025 | DATE PAYMENT APPEAL FEE | 04.04.2025 | APPEAL RESULT | INPADOC data Tooltip | The EPO does not accept any responsibility for the accuracy of legal status data relating to the post-grant phase, including but not limited to their completeness and fitness for specific purposes, nor can it guarantee that such data are up to date. For authoritative information, please refer to the relevant national patent authority. | Event date: | 13.02.2019 | | Event description: | REQUEST FOR EXAMINATION FILED | Effective DATE: | 20180927 | | Event date: | 13.02.2019 | | Event description: | DESIGNATED CONTRACTING STATES | Kind Code of Ref Document: | A1 | Designated State(s): | AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR | | Event date: | 13.02.2019 | | Event description: | REQUEST FOR EXTENSION OF THE EUROPEAN PATENT | Validation States: | BA ME | | Event date: | 11.01.2019 | | Event description: | PUBLIC REFERENCE MADE UNDER ARTICLE 153(3) EPC TO A PUBLISHED INTERNATIONAL APPLICATION THAT HAS ENTERED THE EUROPEAN PHASE | Free Format Text: | ORIGINAL CODE: 0009012 | | Event date: | 11.01.2019 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: REQUEST FOR EXAMINATION WAS MADE | | Event date: | 13.10.2017 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE | | Event date: | 07.06.2017 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: UNKNOWN | | Event date: | 10.04.2019 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: REQUEST FOR EXAMINATION WAS MADE | | Event date: | 17.11.2021 | | Event description: | DESPATCH OF COMMUNICATION OF INTENTION TO GRANT A PATENT | Free Format Text: | ORIGINAL CODE: EPIDOSNIGR1 | | Event date: | 17.11.2021 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: GRANT OF PATENT IS INTENDED | | Event date: | 15.12.2021 | | Event description: | INTENTION TO GRANT ANNOUNCED | Effective DATE: | 20211118 | | Event date: | 29.03.2022 | | Event description: | GRANT FEE PAID | Free Format Text: | ORIGINAL CODE: EPIDOSNIGR3 | | Event date: | 29.04.2022 | | Event description: | (EXPECTED) GRANT | Free Format Text: | ORIGINAL CODE: 0009210 | | Event date: | 29.04.2022 | | Event description: | INFORMATION ON THE STATUS OF AN EP PATENT APPLICATION OR GRANTED EP PATENT | Free Format Text: | STATUS: THE PATENT HAS BEEN GRANTED | | Event date: | 01.06.2022 | | Event description: | DESIGNATED CONTRACTING STATES | Kind Code of Ref Document: | B1 | Designated State(s): | AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR | | Event date: | 01.06.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG GB FG4D | Code Expl.: | +EUROPEAN PATENT GRANTED | | Event date: | 15.06.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG DE R096 602017057996 DE | Code Expl.: | +DPMA PUBLICATION OF MENTIONED EP PATENT GRANT | | Event date: | 15.06.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG AT REF 1494914 AT T | Code Expl.: | +REFERENCE TO AT NUMBER (EP PATENT VALIDATED IN AUSTRIA) | Effective DATE: | 20220615 | | Event date: | 15.06.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG CH EP | Code Expl.: | +EUROPEAN PATENT TAKES EFFECT AS A NATIONAL PATENT IN CH/LI | | Event date: | 22.06.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG IE FG4D | Code Expl.: | +EUROPEAN PATENTS GRANTED DESIGNATING IRELAND | | Event date: | 10.08.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG NL FP | Code Expl.: | TRANSLATION FOR EP FILED (ENTRY OF EP INTO COUNTRY) | | Event date: | 29.08.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG DK T3 | Code Expl.: | +EP PATENT WITH DANISH CLAIMS | Effective DATE: | 20220826 | | Event date: | 30.08.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG PT SC4A 3439637 PT 20220830 T | Code Expl.: | +TRANSLATION IS AVAILABLE | Free Format Text: | AVAILABILITY OF NATIONAL TRANSLATION | Effective DATE: | 20220823 | | Event date: | 20.09.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG SE TRGR | Code Expl.: | +TRANSLATION OF GRANTED EP PATENT | | Event date: | 03.10.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG NO T2 | Code Expl.: | +ENTRY OF EP PATENT INTO NATIONAL PHASE OF NORWAY [PUBL. OF TRANSLATION] | Effective DATE: | 20220601 | | Event date: | 12.08.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG FI FGE | Code Expl.: | +EP PATENT VALIDATED IN FINLAND | | Event date: | 30.09.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG MA VAGR 43793 MA B1 | Code Expl.: | +VALIDATION OF EP PATENT IN VALIDATION STATE [INFORMATION PROVIDED BY NATIONAL OFFICE] | | Event date: | 11.10.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG ES FG2A 2924881 ES T3 | Code Expl.: | +DEFINITIVE PROTECTION | Effective DATE: | 20221011 | | Event date: | 26.10.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG GR EP 20220401691 GR | Code Expl.: | +EP PATENT VALIDATED IN GREECE | Effective DATE: | 20221010 | | Event date: | 31.10.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG MD VAGR 3439637 MD 20221031 T2 | Code Expl.: | +TRANSLATION OF VALIDATED EUROPEAN PATENT | | Event date: | 17.10.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG EE FG4A E022537 EE | Code Expl.: | +TRANSLATION OF THE SPECIFICATION OF EUROPEAN PATENT VALID IN ESTONIA | Effective DATE: | 20220822 | | Event date: | 10.11.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG SK T3 E 40351 SK | Code Expl.: | +TRANSLATION OF EUROPEAN PATENT SPECIFICATION INTO SLOVAK | | Event date: | 28.11.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG HU AG4A E059531 HU | Code Expl.: | +FILING OF THE TRANSLATION OF THE TEXT OF EUROPEAN PATENTS | | Event date: | 04.04.2017 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG HR TUEP P20221073 HR | Code Expl.: | REQUEST FOR EP VALIDATION RECEIVED | | Event date: | 25.11.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG HR T1PR P20221073 HR | Code Expl.: | +EP PATENT VALIDATED IN CROATIA | | Event date: | 24.08.2022 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG RO EPE | Code Expl.: | +EP PATENT VALID IN ROMANIA | | Event date: | 24.02.2023 | | Event description: | OPPOSITION FILED | Free Format Text: | ORIGINAL CODE: 0009260 | | Event date: | 22.02.2023 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG DE R026 602017057996 DE | Code Expl.: | -OPPOSITION FILED AGAINST PATENT | | Event date: | 15.03.2023 | | Event description: | NOTICE OF OPPOSITION AND REQUEST TO FILE OBSERVATION + TIME LIMIT SENT | Free Format Text: | ORIGINAL CODE: EPIDOSNOBS2 | | Event date: | 29.03.2023 | | Event description: | OPPOSITION FILED | OPPONENT: | ELKINGTON AND FIFE LLP | Effective DATE: | 20230222 | | Event date: | 31.03.2023 | | Event description: | LAPSED IN A CONTRACTING STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO] | Ref Country Code: | AL | Free Format Text: | LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT | Effective DATE: | 20220601 | | Event date: | 14.04.2023 | | Event description: | REFERENCE TO A NATIONAL CODE | Event code: | REG HR ODRP P20221073 HR | Code Expl.: | +RENEWAL FEE FOR THE MAINTENANCE OF A PATENT | Payment DATE: | 20230302 | Year of Fee Payment: | 7 | | Event date: | 31.05.2023 | | Event description: | PARTY DATA CHANGED (PATENT OWNER DATA CHANGED OR RIGHTS OF A PATENT TRANSFERRED) | OWNER: | ALFASIGMA S.P.A. | | Event date: | 31.05.2023 | | Event description: | ANNUAL FEE PAID TO VALIDATION STATE [ANNOUNCED VIA POSTGRANT INFORMATION FROM NATIONAL OFFICE TO EPO] | Ref Country Code: | MD | Payment DATE: | 20230216 | Year of Fee Payment: | 07 | | Event date: | 14.06.2023 | | Event description: | OPT-OUT OF THE COMPETENCE OF THE UNIFIED PATENT COURT (UPC) REGISTERED | Effective DATE: | 20230418 | | Event date: | 28.06.2023 | | Event description: | INFORMATION MODIFIED RELATED TO COMMUNICATION OF A NOTICE OF 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