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EP3465156

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Extract from the Register of European Patents

EP About this file: EP3465156

EP3465156 - FLUORESCENCE LIFETIME MICROSCOPIC METHOD WITH TIME-CORRELATED SINGLE PHOTON COUNTING WHICH ALLOWS HIGHER LIGHT INTENSITIES, AND CORRESPONDING DEVICE [Right-click to bookmark this link]
Former [2019/15]	FLUORESCENCE-LIFETIME IMAGING MICROSCOPY METHOD HAVING TIME-CORRELATED SINGLE-PHOTON COUNTING, WHICH METHOD PERMITS HIGHER LIGHT INTENSITIES
	[2019/35]
Status	No opposition filed within time limit Status updated on 22.01.2021 Database last updated on 03.10.2024
Former	The patent has been granted Status updated on 14.02.2020
Former	Grant of patent is intended Status updated on 08.10.2019
Former	Request for examination was made Status updated on 08.03.2019
Former	The international publication has been made Status updated on 01.12.2017
Former	unknown Status updated on 15.06.2017
Most recent event Tooltip	15.07.2022	Lapse of the patent in a contracting state New state(s): MK	published on 17.08.2022 [2022/33]
Applicant(s)	For all designated states Leica Microsystems CMS GmbH CPTD Ernst-Leitz-Strasse 17-37 35578 Wetzlar / DE
	[2019/15]
Inventor(s)	01 / SEYFRIED, Volker Jahnstraße 28 69226 Nußloch / DE
	02 / WIDZGOWSKI, Bernd Bahnhofstrasse 6 69221 Dossenheim / DE
	03 / HECHT, Frank Collinistrasse 5 68161 Mannheim / DE
	[2019/15]
Representative(s)	Schaumburg und Partner Patentanwälte mbB Mauerkircherstraße 31 81679 München / DE
	[N/P]
Former [2019/15]	Schaumburg und Partner Patentanwälte mbB Postfach 86 07 48 81634 München / DE
Application number, filing date	17727541.9	24.05.2017
	[2019/15]
	WO2017EP62656
Priority number, date	DE201610109723	25.05.2016 Original published format: DE102016109723
	[2019/15]
Filing language	DE
Procedural language	DE
Publication	Type:	A1 Application with search report
	No.:	WO2017202980
	Date:	30.11.2017
	Language:	DE
	[2017/48]
	Type:	A1 Application with search report
	No.:	EP3465156
	Date:	10.04.2019
	Language:	DE
	The application published by WIPO in one of the EPO official languages on 30.11.2017 takes the place of the publication of the European patent application.
	[2019/15]
	Type:	B1 Patent specification
	No.:	EP3465156
	Date:	18.03.2020
	Language:	DE
	[2020/12]
Search report(s)	International search report - published on:	EP	30.11.2017
Classification	IPC:	G01N21/64	[2019/15]
	CPC:	G01N21/6408 (EP,US); G01N21/6458 (US)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/15]
Extension states	BA	Not yet paid
	ME	Not yet paid
Validation states	MA	Not yet paid
	MD	Not yet paid
Title	German:	FLUORESZENZLEBENSDAUER-MIKROSKOPIEVERFAHREN MIT ZEITKORRELIERTER EINZELPHOTONENZÄHLUNG WELCHES HÖHERE LICHTINTENSITÄTEN ZULÄSST, UND ENTSPRECHENDE VORRICHTUNG	[2019/35]
	English:	FLUORESCENCE LIFETIME MICROSCOPIC METHOD WITH TIME-CORRELATED SINGLE PHOTON COUNTING WHICH ALLOWS HIGHER LIGHT INTENSITIES, AND CORRESPONDING DEVICE	[2019/35]
	French:	MÉTHODE DE MICROSCOPIE POUR DÉTERMINER LA DURÉE DE VIE DE FLUORESCENCE BASÉ SUR LE COMPTAGE MONOPHOTONIQUE À CORRELATION TEMPORELLE QUI PERMET DES INTENSITÉS LUMINEUSES SUPÉRIEURES, ET DISPOSITF CORRESPONDANT	[2019/35]
	Former [2019/15]	FLUORESZENZLEBENSDAUER-MIKROSKOPIEVERFAHREN MIT ZEITKORRELIERTER EINZELPHOTONENZÄHLUNG WELCHES HÖHERE LICHTINTENSITÄTEN ZULÄSST
	Former [2019/15]	FLUORESCENCE-LIFETIME IMAGING MICROSCOPY METHOD HAVING TIME-CORRELATED SINGLE-PHOTON COUNTING, WHICH METHOD PERMITS HIGHER LIGHT INTENSITIES
	Former [2019/15]	PROCÉDÉ DE MICROSCOPIE À DURÉE DE VIE DE FLUORESCENCE À COMPTAGE DE PHOTONS UNIQUES CORRÉLÉ DANS LE TEMPS, LEQUEL PROCÉDÉ AUTORISE DES INTENSITÉS LUMINEUSES ÉLEVÉES
Entry into regional phase	20.12.2018	National basic fee paid
	20.12.2018	Designation fee(s) paid
	20.12.2018	Examination fee paid
Examination procedure	20.12.2018	Examination requested [2019/15]
	20.12.2018	Date on which the examining division has become responsible
	05.02.2019	Amendment by applicant (claims and/or description)
	09.10.2019	Communication of intention to grant the patent
	06.02.2020	Fee for grant paid
	06.02.2020	Fee for publishing/printing paid
	06.02.2020	Receipt of the translation of the claim(s)
Opposition(s)	21.12.2020	No opposition filed within time limit [2021/08]
Fees paid	Renewal fee
	29.05.2019	Renewal fee patent year 03
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	24.05.2017
	AL	18.03.2020
	CY	18.03.2020
	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	MK	18.03.2020
	MT	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SI	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	TR	18.03.2020
	IE	24.05.2020
	LU	24.05.2020
	BE	31.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
	[2022/31]
Former [2022/30]	HU	24.05.2017
	AL	18.03.2020
	CY	18.03.2020
	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	MT	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SI	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	TR	18.03.2020
	IE	24.05.2020
	LU	24.05.2020
	BE	31.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2022/27]	HU	24.05.2017
	CY	18.03.2020
	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	MT	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SI	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	TR	18.03.2020
	IE	24.05.2020
	LU	24.05.2020
	BE	31.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/24]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SI	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	IE	24.05.2020
	LU	24.05.2020
	BE	31.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/20]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	IE	24.05.2020
	LU	24.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/15]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	LU	24.05.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/10]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	NL	18.03.2020
	PL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/09]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	IT	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	MC	18.03.2020
	NL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2021/08]	CZ	18.03.2020
	DK	18.03.2020
	EE	18.03.2020
	ES	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	CH	31.05.2020
	LI	31.05.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2020/50]	CZ	18.03.2020
	EE	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2020/49]	CZ	18.03.2020
	FI	18.03.2020
	HR	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SK	18.03.2020
	SM	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2020/48]	FI	18.03.2020
	HR	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RO	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	SM	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
	PT	12.08.2020
Former [2020/47]	FI	18.03.2020
	HR	18.03.2020
	LT	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
Former [2020/46]	FI	18.03.2020
	HR	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
	IS	18.07.2020
Former [2020/45]	FI	18.03.2020
	HR	18.03.2020
	LV	18.03.2020
	NL	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
Former [2020/39]	FI	18.03.2020
	HR	18.03.2020
	LV	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	BG	18.06.2020
	NO	18.06.2020
	GR	19.06.2020
Former [2020/38]	FI	18.03.2020
	HR	18.03.2020
	LV	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	NO	18.06.2020
	GR	19.06.2020
Former [2020/37]	FI	18.03.2020
	HR	18.03.2020
	LV	18.03.2020
	RS	18.03.2020
	SE	18.03.2020
	NO	18.06.2020
Former [2020/35]	FI	18.03.2020
	NO	18.06.2020
Cited in	International search	[AD]DE102011055330 (LEICA MICROSYSTEMS [DE]) [AD] 1-21 * paragraphs [0016] - [0023] ** paragraphs [0029] - [0036] *;
		[A] - Michael Wahl, "The Principle of Time-Correlated Single Photon Counting", PicoQuant Technical Note, (20140624), pages 1 - 14, URL: http://www.picoquant.com/images/uploads/page/files/7253/technote_tcspc.pdf, (20140819), XP055135297 [A] 1-21 * pages 1-3 * * page 5, column r, paragraph l - page 6, column r, paragraph 1 * * page 9 *
		[A] - JOCHEN ARLT ET AL, "A study of pile-up in integrated time-correlated single photon counting systems", REVIEW OF SCIENTIFIC INSTRUMENTS., US, (20131010), vol. 84, no. 10, doi:10.1063/1.4824196, ISSN 0034-6748, page 103105, XP055278177 [A] 1-21 * pages 103105-1 - pages 103105-2 * * pages 103105-7 - pages 103105-9 * DOI: http://dx.doi.org/10.1063/1.4824196
		[A] - SEBASTIAN ISBANER ET AL, "Dead-time correction of fluorescence lifetime measurements and fluorescence lifetime imaging", OPTICS EXPRESS, (20160421), vol. 24, no. 9, doi:10.1364/OE.24.009429, pages 9429 - 9445, XP055396466 [A] 1-21 * page 9430 - page 9434 * * figure 6 * * page 9443 - page 9444 * DOI: http://dx.doi.org/10.1364/OE.24.009429
	by applicant	DE4339784
		US7215421
		WO2010089363
		US7999238
		DE102011052334
		DE102011055330
		DE102011055945
		- BAJZER, Z. ET AL., "Maximum-Likelihood Method For The Analysis Of Time-Resolved Fluorescence Decay Curves", EUROPEAN BIOPHYSICS JOURNAL, (1991), vol. 20, no. 5, pages 247 - 262

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