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EP3478679
European procedure
Extract from the Register of European Patents
EP Citations: EP3478679
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| Type: | Non-patent literature | Publication information: | "Chemical Neuroscience", 2014, AMERICAN CHEMICAL SOCIETY, article MICHAEL ET AL.: "Selective Activation of M4 Muscarinic Acetylcholine Receptors reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents" | Type: | Non-patent literature | Publication information: | BYNUM, NELLIE E. ET AL.: "Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100", NEUROPSYCHOPHARMACOLOGY, 2014, pages 1 - 16 | Type: | Non-patent literature | Publication information: | CHAN, W.Y. ET AL.: "Allosteric Modulation of the Muscarinic M4 receptor as an Approach to Treating Schizophrenia", PNAS, vol. 105, no. 31, August 2008 (2008-08-01), pages 10978 | Type: | Non-patent literature | Publication information: | BYUN, NELLIE ET AL.: "Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100", NEUROPSYCHOPHARMACOLOGY, 2014, pages 1 - 16 | Type: | Non-patent literature | Publication information: | SHIRLEY, JANA K ET AL.: "An allosteric potentiator of M4 mACHR modulates hippocampal synaptic transmission", NATURE CHEMICAL BIOLOGY, vol. 4, no. 1, January 2008 (2008-01-01) | Type: | Non-patent literature | Publication information: | DASARI, SAMEERA: "M1 and M4 Receptors Modulate Hippocampal Pyramidal Neurons", J. NEUROPHYSIOLOGY, vol. 105, 2011, pages 779 - 792 | Type: | Non-patent literature | Publication information: | TAMMINGA, CAROL A.: "Glutamate Dysfunction in Hippocampus: Relevance of Dentate Gyrus and CA3 Signaling", SCHIZOPHRENIA BULLETIN, vol. 38, no. 5, 2012, pages 927 - 935 | Type: | Non-patent literature | Publication information: | QUIROZ ET AL., ANN NEUROL, 2010 | Type: | Non-patent literature | Publication information: | FILIPINI ET AL., PNAS, 2009 | Type: | Non-patent literature | Publication information: | BAKKER, A.: "Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance", NEUROMALGE: CLINICAL, vol. 7, 2015, pages 688 - 698 | Type: | Non-patent literature | Publication information: | HALEBLIAN, J. PHARM. SCI., vol. 64, no. 8, August 1975 (1975-08-01), pages 1269 - 1288 | Type: | Non-patent literature | Publication information: | O. ALMARSSON; M. J. ZAWOROTKO, CHEM. COMMUN., vol. 17, 2004, pages 1889 - 1896 | Type: | Non-patent literature | Publication information: | J. K. HALEBLIAN, J. PHARM. SCI., vol. 64, 1975, pages 1269 - 1288 | Type: | Non-patent literature | Publication information: | FREEDMAN, T. B. ET AL.: "Absolute Configuration Determination of Chiral Molecules in the Solution State Using Vibrational Circular Dichroism.", CHIRALITY, vol. 15, 2003, pages 743 - 758 | Type: | Non-patent literature | Publication information: | BRINGMANN, G. ET AL.: "Atroposelective Synthesis of Axially Chiral Biaryl Compounds", ANGEW. CHEM., INT. ED, vol. 44, 2005, pages 5384 - 5427, XP055022810, DOI: doi:10.1002/anie.200462661 | DOI: | http://dx.doi.org/10.1002/anie.200462661 | Type: | Non-patent literature | Publication information: | STAHL; WERMUTH: "Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH | Type: | Non-patent literature | Publication information: | N. H. HARTSHORNE; A. STUART: "Crystals and the Polarizing Microscope, 4th Edition", 1970, EDWARD ARNOLD | Type: | Non-patent literature | Publication information: | T. HIGUCHI; W. STELLA: "Pro-drugs as Novel Delivery Systems", vol. 14, ACS SYMPOSIUM SERIES | Type: | Non-patent literature | Publication information: | E. B. ROCHE,: "Bioreversible Carriers in Drug Design", 1987, PERGAMON PRESS | Type: | Non-patent literature | Publication information: | H. BUNDGAARD: "Design of Prodrugs", 1985, ELSEVIER | Type: | Non-patent literature | Publication information: | VALENTINO STELLA, RONALD BORCHARDT, MICHAEL HAGEMAN, REZA OLIYAI, HANS MAAG, JEFFERSON TILLEY,: "Prodrugs: Challenges and Reward", 2007, SPRINGER, pages: 134 - 175 | Type: | Non-patent literature | Publication information: | J. W. F. MCOMIE: "Protective Groups in Organic Chemistry", 1973, PLENUM PRESS | Type: | Non-patent literature | Publication information: | T. W. GREENE; P. G. M. WUTS: "Protective Groups in Organic Synthesis, 3rd edition,", 1999, WILEY-INTERSCIENCE | Type: | Non-patent literature | Publication information: | PANCANI, T. ET AL.: "Allosteric activation of M4 improve behavioral and physiological alterations in early symptomatic YAC128 mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF THE SCIENCES OF THE UNITED STATES OF AMERICA, vol. 112, no. 45, 10 November 2015 (2015-11-10), pages 14078 - 83 | Type: | Non-patent literature | Publication information: | FELDER ET AL.: "Elucidating the Role of Muscarinic Receptors in Psychosis", LIFE SCI, vol. 68, 2001, pages 2605 - 2613 | Type: | Non-patent literature | Publication information: | TZAVARA ET AL.: "M4 Muscarinic Receptors Regulate the Dynamics of Cholinergic and Dopaminergic Neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies", FASEB J., vol. 18, 2004, pages 1410 - 1412 | Type: | Non-patent literature | Publication information: | BRADY ET AL.: "Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 327, no. 3, XP055081736, DOI: doi:10.1124/jpet.108.140350 | DOI: | http://dx.doi.org/10.1124/jpet.108.140350 | Type: | Non-patent literature | Publication information: | FOSTER, DANIEL J.: "Activation of M1 and M4 muscarinic receptors as potential treatments for Alzheimer's disease and schizophrenia", NEUROPSYCHIATRIC DISEASE AND TREATMENT, vol. 2014, no. 10, pages 183 - 191 | Type: | Non-patent literature | Publication information: | DILLON, CAROL: "Behavioral symptoms related to cognitive impairment", NEUROPSYCHIATRIC DISEASE AND TREATMENT, vol. 9, 2013, pages 1443 - 1455 | Type: | Non-patent literature | Publication information: | FINNIN; MORGAN, J. PHARM. SCI, vol. 88, no. 10, 1999, pages 955 - 958 | Type: | Non-patent literature | Publication information: | HOOVER, JOHN E.: "Remington's Pharmaceutical Sciences", 1975, MACK PUBLISHING CO. | Type: | Non-patent literature | Publication information: | LIBERMAN ET AL.,: "Pharmaceutical Dosage Forms", 1980, MARCEL DECKER | Type: | Non-patent literature | Publication information: | KIBBE ET AL.,: "Handbook of Pharmaceutical Excipients (3rd Ed.),", 1999, AMERICAN PHARMACEUTICAL ASSOCIATION | Type: | Non-patent literature | Publication information: | "COMPENDIUM OF ORGANIC SYNTHETIC METHODS", vol. I-XII, WILEY-INTERSCIENCE | Type: | Non-patent literature | Publication information: | T. W. GREENE: "Protective Groups in Organic Chemistry", 1981, JOHN WILEY & SONS | Type: | Non-patent literature | Publication information: | T. W. GREENE; P. G. M. WUTS: "Protective Groups in Organic Chemistry", 2006, JOHN WILEY & SONS | Type: | Non-patent literature | Publication information: | SHELDRICK, G. M., SADABS, 2009 | Type: | Non-patent literature | Publication information: | SHELDRICK, G. M., ACTA CRYST., vol. A71, 2015, pages 3 - 8 | Type: | Non-patent literature | Publication information: | SHELDRICK, G. M., ACTA CRYST., vol. C71, 2015, pages 3 - 8 | Type: | Non-patent literature | Publication information: | MULLER, P., CRYSTALLOGRAPHY REVIEWS, vol. 15, 2009, pages 57 - 83 | Type: | Non-patent literature | Publication information: | PARSONS, S.; FLACK, H. D., ACTA CRYST., vol. A60, 2004, pages s61 | Type: | Non-patent literature | Publication information: | HOOFT, R. W. W.; STRAVER, L. H.; SPEK, A. L., J. APPL. CRYST., vol. 41, 2008, pages 96 - 103 |