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Extract from the Register of European Patents

EP About this file: EP3488012

EP3488012 - DNA PROBES FOR IN SITU HYBRIDIZATION ON CHROMOSOMES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  25.03.2022
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  16.04.2021
FormerGrant of patent is intended
Status updated on  22.12.2020
FormerRequest for examination was made
Status updated on  17.11.2020
FormerGrant of patent is intended
Status updated on  19.07.2020
FormerRequest for examination was made
Status updated on  26.04.2019
FormerThe international publication has been made
Status updated on  03.02.2018
Formerunknown
Status updated on  09.08.2017
Most recent event   Tooltip27.04.2024Lapse of the patent in a contracting state
New state(s): MK
published on 29.05.2024  [2024/22]
Applicant(s)For all designated states
Invivo Biotech Services GmbH
Neuendorfstraße 24a
16761 Hennigsdorf - Brandenburg / DE
[2019/22]
Inventor(s)01 / WEGLÖHNER, Wolfgang
c/o InVivo BioTech Services GmbH
Neuendorfstraße 24a
16761 Hennigsdorf - Brandenburg / DE
02 / SCHINDLER, Sabrina
c/o InVivo BioTech Services GmbH
Neuendorfstraße 24a
16761 Hennigsdorf - Brandenburg / DE
 [2019/22]
Representative(s)Boßmeyer, Jens
Bruker Daltonics GmbH & Co. KG
Fahrenheitstraße 4
28359 Bremen / DE
[N/P]
Former [2019/22]Boßmeyer, Jens
Bruker Daltonik GmbH
Fahrenheitstraße 4
28359 Bremen / DE
Application number, filing date17745665.414.07.2017
[2019/22]
WO2017EP67801
Priority number, dateDE20161011368125.07.2016         Original published format: DE102016113681
DE20161012484419.12.2016         Original published format: DE102016124844
[2019/22]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2018019610
Date:01.02.2018
Language:DE
[2018/05]
Type: A1 Application with search report 
No.:EP3488012
Date:29.05.2019
Language:DE
The application published by WIPO in one of the EPO official languages on 01.02.2018 takes the place of the publication of the European patent application.
[2019/22]
Type: B1 Patent specification 
No.:EP3488012
Date:19.05.2021
Language:DE
[2021/20]
Search report(s)International search report - published on:EP01.02.2018
ClassificationIPC:C12Q1/6841, C12Q1/6853
[2020/31]
CPC:
C12Q1/6841 (EP,KR,US); C12Q1/6827 (US); C12Q1/6853 (EP,KR,US);
C12Q2525/155 (KR); C12Q2565/102 (KR); C12Q2600/156 (US);
C12Q2600/16 (US) (-)
C-Set:
C12Q1/6841, C12Q2525/155, C12Q2565/102 (EP);
C12Q1/6853, C12Q2525/155, C12Q2565/102 (EP)
Former IPC [2019/22]C12Q1/68
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/22]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:DNA-SONDEN FÜR EINE IN-SITU HYBRIDISIERUNG AN CHROMOSOMEN[2019/22]
English:DNA PROBES FOR IN SITU HYBRIDIZATION ON CHROMOSOMES[2019/22]
French:SONDES D'ADN POUR HYBRIDATION IN SITU À DES CHROMOSOMES[2019/22]
Entry into regional phase06.02.2019National basic fee paid 
06.02.2019Designation fee(s) paid 
06.02.2019Examination fee paid 
Examination procedure05.03.2018Request for preliminary examination filed
International Preliminary Examining Authority: EP
30.01.2019Amendment by applicant (claims and/or description)
06.02.2019Examination requested  [2019/22]
06.02.2019Date on which the examining division has become responsible
20.07.2020Communication of intention to grant the patent
17.11.2020Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
23.12.2020Communication of intention to grant the patent
30.03.2021Fee for grant paid
30.03.2021Fee for publishing/printing paid
13.04.2021Receipt of the translation of the claim(s)
Opposition(s)22.02.2022No opposition filed within time limit [2022/17]
Fees paidRenewal fee
25.07.2019Renewal fee patent year 03
23.07.2020Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.07.2017
AL19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
IT19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
MK19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
IE14.07.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
[2024/22]
Former [2023/33]HU14.07.2017
AL19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
IT19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
IE14.07.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2023/30]AL19.05.2021
CY19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
IT19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
IE14.07.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/36]AL19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
IT19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
IE14.07.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/35]AL19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
IE14.07.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/34]AL19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
LU14.07.2021
BE31.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/29]AL19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SI19.05.2021
SK19.05.2021
SM19.05.2021
LU14.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/26]AL19.05.2021
CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
LU14.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/23]CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
LU14.07.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/21]CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
CH31.07.2021
LI31.07.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
PT20.09.2021
IS22.12.2021
Former [2022/18]CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
MC19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
PT20.09.2021
IS22.12.2021
Former [2022/10]CZ19.05.2021
DK19.05.2021
EE19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
PT20.09.2021
IS22.12.2021
Former [2022/09]CZ19.05.2021
DK19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RO19.05.2021
RS19.05.2021
SE19.05.2021
SK19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/08]CZ19.05.2021
DK19.05.2021
ES19.05.2021
FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/07]FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
SM19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2022/04]FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
NL19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/52]FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
PL19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/51]FI19.05.2021
HR19.05.2021
LT19.05.2021
LV19.05.2021
RS19.05.2021
SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
IS19.09.2021
PT20.09.2021
Former [2021/50]FI19.05.2021
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SE19.05.2021
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LT19.05.2021
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SE19.05.2021
BG19.08.2021
NO19.08.2021
GR20.08.2021
Former [2021/47]FI19.05.2021
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LT19.05.2021
Cited inInternational search[A]DE10240021  (ADNAGEN AG [DE]) [A] 1-14 * claims 1-6 *;
 [XI]  - GISSELSSON DAVID, "Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources", vol. 23, no. 1, doi:10.1023/A:1013129212367, ISSN 1381-5741, (20010301), pages 23 - 28, METHODS IN CELL SCIENCE, DORDRECHT [U.A.] : KLUWER, NL, URL: http://epo.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3PS8MwFA5TELz4G60_IAdBL5E2adP0KMPNg6c5BU8laRIR3Vba9bD_3pe2dmVe9BAKbV4oeSHf95rX7yF0TUPJFRU-iXmmSSg1JyLJFAGqr8PEZJLX8sVvw3A6jifj8GmA_O7Txfzz7udEst6o-1o8AQN0orXoGGy6bjG58Pz5tdt6aVKXaw0AhkgEWLmh5dOz7wFOdwK6oRZaI8xo___vdoD2WjaJ7xv3H6KBmR-hnaa-, XP009500605 [X] 1,2,4,6-11,13 * page 26, column r - page 27 * [I] 3,5,12,14

DOI:   http://dx.doi.org/10.1023/A:1013129212367
 [A]  - SHELAGH BOYLE ET AL, "Fluorescence in situ hybridization with high-complexity repeat-free oligonucleotide probes generated by massively parallel synthesis", CHROMOSOME RESEARCH, KLUWER ACADEMIC PUBLISHERS, DO, (20111018), vol. 19, no. 7, doi:10.1007/S10577-011-9245-0, ISSN 1573-6849, pages 901 - 909, XP019974141 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1007/s10577-011-9245-0
 [A]  - QUNFENG LOU ET AL, "Single-copy gene-based chromosome painting in cucumber and its application for chromosome rearrangement analysis in Cucumis", THE PLANT JOURNAL, GB, (20140312), vol. 78, no. 1, doi:10.1111/tpj.12453, ISSN 0960-7412, pages 169 - 179, XP055413186 [A] 1-14 * page 171 *

DOI:   http://dx.doi.org/10.1111/tpj.12453
 [A]  - BOGOMOLOV A G ET AL, "Fluorescence in situ hybridization with DNA probes derived from individual chromosomes and chromosome regions", vol. 48, no. 6, doi:10.1134/S002689331406003X, ISSN 0026-8933, (20141101), pages 767 - 777, MOLECULAR BIOLOGY : COVER-TO-COVER TRANSLATION = MOLEKULYARNAYA BIOLOGIYA, ACADEMY OF SCIENCES OF THE USSR, RU, URL: http://epo.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8QwEB5UEL34BldXyEEvYqWmaZoel9XVg3jwhZ5C8yguuqvsQ9h_70wf62M9iMeWSVomk8wrMx_AvlNGoibPAlKOgYhsHBgb5YGjqL7IpROGAvqPbXF7nlyfi8s54NPQRf_5uM5IFgd1CTsiqKSXS8KGR48AlXT0gMcuiRM56Df308QBqe_yVocMiLpKZP46w3dV9Glf_kiJFpqms_qff1yDlcquZK1SENZhzvc3YLFE, XP009500604 [A] 1-14 * page 774 - page 775 *

DOI:   http://dx.doi.org/10.1134/S002689331406003X
by applicantDE69032920T
 US6150160
 WO0106014
 EP1127163
 WO0188089
 US2003022204
 EP1285093
 US2003108943
 US2003194718
 US2004029298
 US2004161773
 WO2004083386
 WO2004097050
 US6828097
 US7014997
 EP1669902
 WO2007053245
 EP2069537
 DE102010029855
 US8407013
 WO2014036525
    - SWENNENHUIS JF et al., "Construction of repeat-free fluorescence in situ hybridization probes", Nucleic Acids Research, (20110000), vol. 40, no. 3, doi:doi:10.1093/nar/gkr1123, page e20, XP002717029

DOI:   http://dx.doi.org/10.1093/nar/gkr1123
    - CRAID JM et al., "Removal of repetitive sequences from FISH probes using PCR-assisted affinity chromatography", HUMAN GENETICS, Springer, vol. 100, pages 472 - 476
    - ROGAN PK et al., "Sequence-based design of single-copy genomic DNA probes for fluorescence in situ hybridization", Genome Res, (20010000), vol. 11, no. 6, doi:doi:10.1101/gr.171701, pages 1086 - 1094, XP002397526

DOI:   http://dx.doi.org/10.1101/gr.171701
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.