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Extract from the Register of European Patents

EP About this file: EP3510048

EP3510048 - METHODS OF TREATING PD-L1 EXPRESSING CANCER [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  22.04.2020
Database last updated on 09.09.2024
FormerRequest for examination was made
Status updated on  14.06.2019
FormerThe international publication has been made
Status updated on  23.03.2018
Formerunknown
Status updated on  29.09.2017
Most recent event   Tooltip27.09.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Mayo Foundation for Medical Education and Research
200 First Street S.W.
Rochester, Minnesota 55905 / US
[2019/29]
Inventor(s)01 / MARKOVIC, Svetomir N.
c/o Mayo Foundation for Medical
Education and Research
200 First Street SW
Rochester, Minnesota 55905 / US
02 / NEVALA, Wendy K.
c/o Mayo Foundation for Medical
Education and Research
200 First Street SW
Rochester, Minnesota 55905 / US
 [2019/29]
Representative(s)Script Intellectual Property LLP
Suite J, Anchor House
School Close
Chandlers Ford
Eastleigh, Hampshire SO53 4DY / GB
[N/P]
Former [2019/29]Mewburn Ellis LLP
City Tower
40 Basinghall Street
London EC2V 5DE / GB
Application number, filing date17768911.405.09.2017
[2019/29]
WO2017US50137
Priority number, dateUS201662383938P06.09.2016         Original published format: US 201662383938 P
[2019/29]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018048816
Date:15.03.2018
Language:EN
[2018/11]
Type: A1 Application with search report 
No.:EP3510048
Date:17.07.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 15.03.2018 takes the place of the publication of the European patent application.
[2019/29]
Search report(s)International search report - published on:EP15.03.2018
ClassificationIPC:C07K16/28, A61K9/00, A61K47/69, A61P35/00, A61K39/395, A61K31/337
[2019/29]
CPC:
C07K16/2827 (EP,KR,US); A61K47/6929 (EP,KR,US); A61K31/337 (EP,KR,US);
A61K31/555 (EP); A61K39/3955 (EP); A61K39/39558 (KR);
A61K45/06 (EP,KR,US); A61K47/643 (EP,KR); A61K47/6849 (EP);
A61K47/6851 (KR); A61P35/00 (EP,KR,US); C07K14/76 (US);
A61K2039/505 (KR); A61K2039/545 (KR); A61K2039/6031 (EP,KR);
A61K2300/00 (KR); A61K9/5169 (EP) (-)
C-Set:
A61K31/337, A61K2300/00 (EP);
A61K31/555, A61K2300/00 (EP);
A61K39/3955, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/29]
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON PD-L1-EXPRIMIERENDEM KREBS[2019/29]
English:METHODS OF TREATING PD-L1 EXPRESSING CANCER[2019/29]
French:PROCÉDÉS DE TRAITEMENT DU CANCER EXPRIMANT PD-L1[2019/29]
Entry into regional phase19.03.2019National basic fee paid 
19.03.2019Designation fee(s) paid 
19.03.2019Examination fee paid 
Examination procedure19.03.2019Examination requested  [2019/29]
19.03.2019Date on which the examining division has become responsible
28.11.2019Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
05.02.2020Amendment by applicant (claims and/or description)
28.04.2020Despatch of a communication from the examining division (Time limit: M04)
04.09.2020Reply to a communication from the examining division
07.12.2020Despatch of a communication from the examining division (Time limit: M06)
09.06.2021Reply to a communication from the examining division
19.01.2023Despatch of a communication from the examining division (Time limit: M04)
22.05.2023Reply to a communication from the examining division
Request for further processing for:05.02.2020Request for further processing filed
05.02.2020Full payment received (date of receipt of payment)
Request granted
13.02.2020Decision despatched
Fees paidRenewal fee
27.09.2019Renewal fee patent year 03
28.09.2020Renewal fee patent year 04
27.09.2021Renewal fee patent year 05
27.09.2022Renewal fee patent year 06
27.09.2023Renewal fee patent year 07
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Cited inInternational search[A]WO2012154861  (MAYO FOUNDATION [US], et al) [A] 1-68* examples 1-8; claims 1-12 *;
 [I]WO2015048520  (GENENTECH INC [US], et al) [I] 1-68 * claims 1-12 *;
 [A]WO2015195476  (MAYO FOUNDATION [US]) [A] 1-68 * example 2; claims 1-11 *;
 [XI]WO2016089873  (CELGENE CORP [US]) [X] 25-27 * paragraph [0211] - paragraph [0213]; figures 1-3; examples 10-12; claims 1-119 * [I] 1-68;
 [I]  - SYLVIA ADAMS ET AL, "Phase Ib trial of atezolizumab in combination with nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC)", vol. 34, no. 5, doi:10.1200/JCO.2016.34.15_suppl.1009, (201605), JOURNAL OF CLINICAL ONCOLOGY, URL: http://ascopubs.org/doi/abs/10.1200/JCO.2016.34.15_suppl.1009, (20171108), XP055422710 [I] 1-68 * the whole document *

DOI:   http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.1009
 [I]  - Anonymous, "Atezolizumab Plus Abraxane Promising New Treatment for Triple-Negative Breast Cancer", (20160107), pages 1 - 2, UNM Comprehensive Cancer Center, URL: http://cancer.unm.edu/2016/01/07/atezolizumab-plus-abraxane-promising-new-treatment-for-triple-negative-breast-cancer/, (20171020), XP055417747 [I] 1-68 * the whole document *
 [I]  - Silas Inman, "OT1-01-06 Atezolizumab/Nab-Paclitaxel Combo Shows High Response Rates in TNBC", INTERNET CITATION, (20151210), OneLive, URL: http://www.onclive.com/conference-coverage/sabcs-2015/atezolizumab-nab-paclitaxel-combo-shows-high-response-rates-in-tnbc, (20171020), XP002775312 [I] 1-68 * the whole document *
 [I]  - Emens L, et al., "OT1-01-06 A phase III randomized trial of atezolizumab in combination with nab-paclitaxel as first line therapy for patients withmetastatic triple-negative breast cancer (mTNBC)", INTERNET CITATION, (20160501), 2015 San Antonio Breast Cancer Symposium, URL: https://www.sabcs.org/Portals/SABCS2016/Documents/SABCS-2015-Abstracts.pdf?v=5, (20171106), XP002775313 [I] 1-68 * the whole document *
 [I]  - Adams S, et al., "Safety and clinical activity of atezolizumab (anti-PDL1) in combination with nab-paclitaxel in patients with metastatictriple-negative breast cancer", INTERNET CITATION, (20160215), 2015 San Antonio Breast Cancer Symposium, URL: https://www.sabcs.org/Portals/SABCS2016/Documents/SABCS-2015-Abstracts.pdf?v=5, (20171115), XP002775314 [I] 1-68 * the whole document *
 [I]  - Anonymous, "A Phase III, Multicenter, Randomized Placebo-Controlled Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Nab Paclitaxel Compared With Placebo With Nab Paclitaxel for Patients With Previously Untreated Metastatic Triple Negative Breast Cancer", (20150421), ClinicalTrials.gov, URL: https://clinicaltrials.gov/archive/NCT02425891/2016_09_01, (20171020), XP055417752 [I] 1-68 * the whole document *
by applicantWO2014055415
 WO2016057554
    - ISHIDA et al., EMBO J., (19920000), vol. 11, page 3887
    - PHILIPS; ATKINS, "Therapeutic uses of anti-PD-1 and anti-PD-Ll antibodies", International Immunology, vol. 27, no. 1, doi:doi:10.1093/intimm/dxu095, pages 39 - 46, XP055217958

DOI:   http://dx.doi.org/10.1093/intimm/dxu095
    - LUSSIER et al., J. Immunotherapy of Cancer, (20150000), vol. 3, page 21
    - KOYAMA et al., Nature Communications, (20160217), vol. 7, pages 1 - 9
    - LANZAVECCHIA et al., Eur. J. Immunol., (19870000), vol. 17, page 105
    - HUSTON et al., Proc. Natl. Acad. Sci. U.S.A., (19880000), vol. 85, pages 5879 - 5883
    - BIRD et al., Science, (19880000), vol. 242, pages 423 - 426
    - Hunkapiller and Hood, Nature, vol. 323, pages 15 - 16
 WO2015US54295
 WO2017US45643
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.