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Extract from the Register of European Patents

EP About this file: EP3439656

EP3439656 - SMALL MOLECULE DUAL-INHIBITORS OF TRPV4 AND TRPA1 FOR SANITIZING AND ANESTHETIZING [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.03.2023
Database last updated on 19.10.2024
FormerExamination is in progress
Status updated on  12.02.2021
FormerRequest for examination was made
Status updated on  11.01.2019
FormerThe international publication has been made
Status updated on  13.10.2017
Most recent event   Tooltip17.03.2023Application deemed to be withdrawnpublished on 19.04.2023  [2023/16]
Applicant(s)For all designated states
Duke University
2812 Erwin Road Suite 306 Office of Science&Technology
Durham, North Carolina 27705 / US
[2019/07]
Inventor(s)01 / LIEDTKE, Wolfgang
11 Altmont Court
Durham, NC 27705 / US
 [2019/07]
Representative(s)Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2019/07]Stafford, Jonathan Alan Lewis
Marks & Clerk LLP
1 New York Street
Manchester M1 4HD / GB
Application number, filing date17779954.107.04.2017
[2019/07]
WO2017US26714
Priority number, dateUS201662319684P07.04.2016         Original published format: US 201662319684 P
US201662331951P04.05.2016         Original published format: US 201662331951 P
US201662337701P17.05.2016         Original published format: US 201662337701 P
[2019/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017177200
Date:12.10.2017
Language:EN
[2017/41]
Type: A1 Application with search report 
No.:EP3439656
Date:13.02.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 12.10.2017 takes the place of the publication of the European patent application.
[2019/07]
Search report(s)International search report - published on:US12.10.2017
(Supplementary) European search report - dispatched on:EP10.02.2020
ClassificationIPC:A61K31/4439, A61K31/426, A61P29/02, A61K45/06, A61K33/18
[2019/49]
CPC:
A61K31/426 (EP,US); A61K31/4439 (EP,US); A61K33/18 (EP,US);
A61K45/06 (EP,US); A61P29/02 (EP,US)
C-Set:
A61K31/426, A61K2300/00 (US,EP);
A61K31/4439, A61K2300/00 (US,EP);
A61K33/18, A61K2300/00 (EP,US)
Former IPC [2019/07]A61K31/4439, A61K31/426
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/07]
TitleGerman:KLEINMOLEKÜLIGE DUAL-INHIBITOREN VON TRPV4 UND TRPA1 ZUR DESINFEKTION UND BETÄUBUNG[2019/07]
English:SMALL MOLECULE DUAL-INHIBITORS OF TRPV4 AND TRPA1 FOR SANITIZING AND ANESTHETIZING[2019/07]
French:INHIBITEURS DOUBLES À PETITES MOLÉCULES DE TRPV4 ET TRPA1 POUR LA DÉSINFECTION ET L'ANESTHÉSIE[2019/07]
Entry into regional phase12.10.2018National basic fee paid 
12.10.2018Search fee paid 
12.10.2018Designation fee(s) paid 
12.10.2018Examination fee paid 
Examination proceduredeletedDate on which the examining division has become responsible
12.10.2018Examination requested  [2019/07]
08.09.2020Amendment by applicant (claims and/or description)
11.02.2021Despatch of a communication from the examining division (Time limit: M05)
21.07.2021Reply to a communication from the examining division
11.08.2022Despatch of a communication from the examining division (Time limit: M03)
22.11.2022Application deemed to be withdrawn, date of legal effect  [2023/16]
13.12.2022Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2023/16]
Fees paidRenewal fee
29.04.2019Renewal fee patent year 03
27.04.2020Renewal fee patent year 04
27.04.2021Renewal fee patent year 05
27.04.2022Renewal fee patent year 06
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Documents cited:Search[Y]WO2016028325  (UNIV DUKE [US], et al) [Y] 1,3-10 * claims 1,11,13 * * examples 14-18 *;
 [YP]  - DEYUAN SU ET AL, "TRPA1 and TRPV1 contribute to iodine antiseptics‐associated pain and allergy", EMBO REPORTS, (20160826), vol. 17, no. 10, doi:10.15252/embr.201642349, ISSN 1469-3178, pages 1422 - 1430, XP055428880 [YP] 1,3-10 * abstract * * introduction * * page 1427, column 1, paragraph 4 *

DOI:   http://dx.doi.org/10.15252/embr.201642349
International search[A]WO2010109334  (GLENMARK PHARMACEUTICALS SA [CH], et al) [A] 3 * pg 8, para 4 *;
 [XY]US2015105406  (GULLAPALLI SRINIVAS [IN], et al) [X] 1-3, 13-17 * para [0014], [0018], [0019], [0027], [0203], [0205], [0206] 16 mg. Note, Thiocolchicoside is an anesthetic drug, as taught by Glenmark.). * [Y] 18, 19;
 [Y]WO2016028325  (UNIV DUKE [US], et al) [Y] 18, 19 * abstract, claims 2, 13, 14 *;
 [XP]  - "TRPA1 and TRPV1 contribute to iodine antiseptics-associated pain and allergy'' (Su et al.", EMBO Reports, (20160826), vol. 17, pages 1422 - 1430, XP055428880 [XP] 1-3, 13-19 * , entire doc. *

DOI:   http://dx.doi.org/10.15252/embr.201642349
by applicantWO9312227
 WO2016028325
    - SU et al., EMBO REPORTS, (20160826), vol. 17, pages 1422 - 1430
    - MOORE et al., Proc. Natl. Acad. Sci. U.S.A, (20130000), vol. 110, pages E3225 - E3234
    - P.J. HEAGERTY et al., Biometrics, (20000000), vol. 56, pages 337 - 44
    - VINCENTDUNCTON, Current Topics in Medicinal Chemistry, (20110000), vol. 11, pages 2216 - 2226
    - LI et al., Environ. Health Perspect, (20110000), vol. 119, pages 784 - 93
    - LUCCARINI et al., J. Pain, (20060000), no. 7, pages 908 - 914
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.