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EP About this file: EP3455760

EP3455760 - METHODS OF DETERMINING GENOMIC HEALTH RISK [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 12.02.2021 Database last updated on 03.09.2024
Former	Request for examination was made Status updated on 15.02.2019
Former	The international publication has been made Status updated on 17.11.2017
Most recent event Tooltip	12.02.2021	Application deemed to be withdrawn	published on 17.03.2021 [2021/11]
Applicant(s)	For all designated states Human Longevity, Inc. 4570 Executive Dr. San Diego, CA 92121 / US
	[2019/12]
Inventor(s)	01 / DI IULIO, Julia 4570 Executive Drive San Diego California 92121 / US
	02 / TELENTI, Amalio 4570 Executive Drive San Diego California 92121 / US
	[2019/12]
Representative(s)	Hutter, Anton, et al Venner Shipley LLP 5 Stirling House Stirling Road The Surrey Research Park Guildford GU2 7RF / GB
	[N/P]
Former [2019/12]	Hutter, Anton, et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD / GB
Application number, filing date	17796629.8	08.05.2017
	[2019/12]
	WO2017US31559
Priority number, date	US201662333653P	09.05.2016 Original published format: US 201662333653 P
	US201662410783P	20.10.2016 Original published format: US 201662410783 P
	[2019/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2017196728
	Date:	16.11.2017
	Language:	EN
	[2017/46]
	Type:	A2 Application without search report
	No.:	EP3455760
	Date:	20.03.2019
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 16.11.2017 takes the place of the publication of the European patent application.
	[2019/12]
Search report(s)	International search report - published on:	KR	26.07.2018
	(Supplementary) European search report - dispatched on:	EP	17.02.2020
Classification	IPC:	C12Q1/6883, C12Q1/6886	[2019/50]
	CPC:	G16B20/20 (EP,US); C12Q1/6883 (EP,US); C12Q1/6886 (EP,US); G16B20/00 (EP,US); G16B30/00 (EP,US); G16B30/10 (EP,US); (+) C12Q1/6869 (EP); C12Q2600/118 (US); C12Q2600/156 (EP,US); G16B20/40 (EP,US) (-)
	C-Set:	C12Q1/6869, C12Q2537/165 (EP,US)
	Former IPC [2019/12]	G06F19/18, G06F19/22, G06F19/24, G06F19/26
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/12]
Title	German:	VERFAHREN ZUR BESTIMMUNG DES GENOMISCHEN GESUNDHEITSRISIKOS	[2019/12]
	English:	METHODS OF DETERMINING GENOMIC HEALTH RISK	[2019/12]
	French:	PROCÉDÉS DE DÉTERMINATION D'UN RISQUE POUR LA SANTÉ GÉNOMIQUE	[2019/12]
Entry into regional phase	08.11.2018	National basic fee paid
	08.11.2018	Search fee paid
	08.11.2018	Designation fee(s) paid
	08.11.2018	Examination fee paid
Examination procedure	deleted	Date on which the examining division has become responsible
	08.11.2018	Examination requested [2019/12]
	19.06.2019	Amendment by applicant (claims and/or description)
	16.09.2020	Application deemed to be withdrawn, date of legal effect [2021/11]
	15.10.2020	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2021/11]
Fees paid	Renewal fee
	28.05.2019	Renewal fee patent year 03
	Penalty fee
	Additional fee for renewal fee
	31.05.2020	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[XI]US2002142295 (BYWATER MARGARET [US], et al) [X] 1-3,5,8-11,13,15 * paragraphs [0013] - [0015] - [0037] - [0040] - [0046] - [0047] - [0095] , [0100] - [0101]; tables 1-2 * * figure 9 * * claims 1,10-11 * [I] 4,6,12;
		[XI] - VARUN AGGARWALA ET AL, "An expanded sequence context model broadly explains variability in polymorphism levels across the human genome", NATURE GENETICS., NEW YORK, US, (20160215), vol. 48, no. 4, doi:10.1038/ng.3511, ISSN 1061-4036, pages 349 - 355, XP055427377 [X] 1-3,8 * abstract * * page 349, column l, paragraph 1 * * page 350, column l, paragraph 1 * * page 353 * * figures 3-4 * [I] 4-7,9-15 DOI: http://dx.doi.org/10.1038/ng.3511
		[XI] - STURM RICHARD A ET AL, "A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color", AMERICAN JOURNAL OF HUMAN GENETICS, AMERICAN SOCIETY OF HUMAN GENETICS, CHICAGO, IL, US, (200802), vol. 82, no. 2, doi:10.1016/J.AJHG.2007.11.005, ISSN 0002-9297, pages 424 - 431, XP009100453 [X] 1-6,9-13 * abstract * * page 425, column r - page 426, column r, paragraph 2 * * page 427 - page 428, column l, paragraph 1 * * figures 2-3 * [I] 7,14 DOI: http://dx.doi.org/10.1016/j.ajhg.2007.11.005
		[I] - BO-YING BAO ET AL, "Genetic variants in ultraconserved regions associate with prostate cancer recurrence and survival", SCIENTIFIC REPORTS, (20160223), vol. 6, no. 1, doi:10.1038/srep22124, XP055638543 [I] 1-15 * abstract * DOI: http://dx.doi.org/10.1038/srep22124
		[IP] - Julia Di Iulio ET AL, bioRxiv, doi:10.1101/082362, (20161021), URL: https://www.biorxiv.org/content/biorxiv/early/2016/10/21/082362.full.pdf, (20191030), XP055637551 [IP] 1-15 * abstract * * page 3, paragraphs 2-3 * * page 4, paragraph last * * page 6, paragraph 3 - page 7, paragraph 1 * * page 8, paragraph 3 * DOI: http://dx.doi.org/10.1101/082362
		[AD] - IULIANA IONITA-LAZA ET AL, "A spectral approach integrating functional genomic annotations for coding and noncoding variants", NATURE GENETICS., NEW YORK, US, (20160104), vol. 48, no. 2, doi:10.1038/ng.3477, ISSN 1061-4036, pages 214 - 220, XP055637830 [AD] 1-15 * the whole document * DOI: http://dx.doi.org/10.1038/ng.3477
		[A] - JIA LI ET AL, "A Dual Model for Prioritizing Cancer Mutations in the Non-coding Genome Based on Germline and Somatic Events", PLOS COMPUTATIONAL BIOLOGY, (20151120), vol. 11, no. 11, doi:10.1371/journal.pcbi.1004583, page e1004583, XP055639341 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1371/journal.pcbi.1004583
		[A] - KHURANA EKTA ET AL, "Role of non-coding sequence variants in cancer", NATURE REVIEWS: GENETICS, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20160119), vol. 17, no. 2, doi:10.1038/NRG.2015.17, ISSN 1471-0064, pages 93 - 108, XP002773468 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1038/nrg.2015.17
		[A] - B. J. WILLCOX ET AL, "FOXO3A genotype is strongly associated with human longevity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20080916), vol. 105, no. 37, doi:10.1073/pnas.0801030105, ISSN 0027-8424, pages 13987 - 13992, XP055012050 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.0801030105
		[T] - DI IULIO JULIA ET AL, "The human noncoding genome defined by genetic diversity", NATURE GENETICS, NATURE PUBLISHING GROUP, NEW YORK, US, vol. 50, no. 3, doi:10.1038/S41588-018-0062-7, ISSN 1061-4036, (20180226), pages 333 - 337, (20180226), XP036462462 [T] * the whole document * DOI: http://dx.doi.org/10.1038/s41588-018-0062-7
		[T] - JULIA DI IULIO, "Interpretation of the noncoding genome in medicine", PERSONALIZED MEDICINE, GB, (20181022), vol. 15, no. 6, doi:10.2217/pme-2018-0065, ISSN 1741-0541, pages 453 - 455, XP055637477 [T] * the whole document * DOI: http://dx.doi.org/10.2217/pme-2018-0065
	International search	[A]US2013332081 (REESE MARTIN G [US], et al) [A] 1-3, 20-27 * See the whole document. *;
		[A]US2015066378 (ROBISON REID [US], et al) [A] 1-3, 20-27 * See abstract; and claims 1-8, 18-21. *;
		[A]WO2015042496 (UNIVERSTIY OF WASHINGTON THROUGH ITS CT FOR COMMERCIALIZATION [US], et al) [A] 1-3, 20-27 * See abstract; and claims 1-7, 15-22. *;
		[A]WO2015105771 (UNIV MICHIGAN [US]) [A] 1-3, 20-27 * See the whole document. *;
		[A] - RITCHIE et al., "Computational approaches to interpreting genomic sequence variation", Genome Medicine, (20140000), vol. 6, no. 87, pages 1 - 11, XP 021208825 [A] 1-3, 20-27 * See the whole document. *
		[PX] - TELENTI et al., "Deep sequencing of 10,000 human genomes", PNAS, (20161000), vol. 113, no. 42, pages 11901 - 11906, XP055506897 [PX] 1-3, 20-27 * See pages 11901-11902, 11905; and figures 2-3. * DOI: http://dx.doi.org/10.1073/pnas.1613365113

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