EP3535024 - TRANSDERMAL OPTOGENETIC PERIPHERAL NERVE STIMULATION [Right-click to bookmark this link] | Status | Grant of patent is intended Status updated on 16.06.2024 Database last updated on 31.08.2024 | |
Former | Examination is in progress Status updated on 25.05.2020 | ||
Former | Request for examination was made Status updated on 09.08.2019 | ||
Former | The international publication has been made Status updated on 11.05.2018 | ||
Former | unknown Status updated on 24.11.2017 | Most recent event Tooltip | 16.06.2024 | New entry: Communication of intention to grant a patent | Applicant(s) | For all designated states Massachusetts Institute Of Technology 77 Massachusetts Avenue Cambridge, MA 02139 / US | [2019/37] | Inventor(s) | 01 /
HERR, Hugh, M. 51 Montrose Street Somerville MA 02143 / US | 02 /
MAIMON, Benjamin 184 Saint Paul Street Apt. 3 Brookline MA 02446 / US | 03 /
ZORZOS, Anthony 40 Shepard Street Apt. 2 Cambridge MA 02138 / US | [2019/37] | Representative(s) | D Young & Co LLP 3 Noble Street London EC2V 7BQ / GB | [N/P] |
Former [2019/37] | D Young & Co LLP 120 Holborn London EC1N 2DY / GB | Application number, filing date | 17797828.5 | 31.10.2017 | [2019/37] | WO2017US59247 | Priority number, date | US201662415817P | 01.11.2016 Original published format: US 201662415817 P | [2019/37] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2018085253 | Date: | 11.05.2018 | Language: | EN | [2018/19] | Type: | A1 Application with search report | No.: | EP3535024 | Date: | 11.09.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 11.05.2018 takes the place of the publication of the European patent application. | [2019/37] | Search report(s) | International search report - published on: | EP | 11.05.2018 | Classification | IPC: | A61N5/06, A01K67/0275, C12N15/86, // A61F2/50, C07K14/47 | [2024/25] | CPC: |
A61N5/0618 (EP);
A61N1/327 (US);
A01K67/0275 (EP);
A61K9/0009 (US);
A61K9/0019 (US);
A61N1/0412 (US);
A61N5/062 (US);
A61N5/0622 (EP,US);
C07K14/47 (EP,US);
C12N15/86 (EP,US);
A01K2217/052 (EP);
A01K2217/206 (EP);
A01K2227/105 (EP);
A01K2267/03 (EP);
A61B2562/0219 (US);
A61B5/1126 (US);
A61F2002/5061 (EP);
A61N2005/0645 (EP,US);
A61N2005/0651 (US);
A61N2005/0659 (US);
A61N2005/0661 (US);
A61N2005/0663 (US);
A61N5/067 (US);
C12N2750/14143 (EP,US);
C12N2830/008 (EP,US)
(-)
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Former IPC [2019/37] | A61N5/06, A61K48/00, A61F2/50 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/37] | Title | German: | TRANSDERMALE OPTOGENETISCHE PERIPHERE NERVENSTIMULATION | [2019/37] | English: | TRANSDERMAL OPTOGENETIC PERIPHERAL NERVE STIMULATION | [2019/37] | French: | STIMULATION OPTOGÉNÉTIQUE TRANSDERMIQUE DU NERF PÉRIPHÉRIQUE | [2019/37] | Entry into regional phase | 31.05.2019 | National basic fee paid | 31.05.2019 | Designation fee(s) paid | 31.05.2019 | Examination fee paid | Examination procedure | 31.05.2019 | Examination requested [2019/37] | 31.05.2019 | Date on which the examining division has become responsible | 20.12.2019 | Amendment by applicant (claims and/or description) | 28.05.2020 | Despatch of a communication from the examining division (Time limit: M04) | 05.10.2020 | Reply to a communication from the examining division | 05.02.2021 | Despatch of a communication from the examining division (Time limit: M04) | 15.06.2021 | Reply to a communication from the examining division | 13.07.2022 | Despatch of a communication from the examining division (Time limit: M02) | 23.09.2022 | Reply to a communication from the examining division | 17.06.2024 | Communication of intention to grant the patent | Fees paid | Renewal fee | 28.10.2019 | Renewal fee patent year 03 | 27.10.2020 | Renewal fee patent year 04 | 27.10.2021 | Renewal fee patent year 05 | 27.10.2022 | Renewal fee patent year 06 | 27.10.2023 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [Y]WO2007024391 (UNIV LELAND STANFORD JUNIOR [US], et al) [Y] 1-10 * paragraphs [0088] , [0147] , [0157] , [0167] , [0208] - [0211] *; | [Y]WO2012061684 (UNIV LELAND STANFORD JUNIOR [US], et al) [Y] 1-10 * page 26, line 11 - page 27, line 9 * * page 37, line 24 - line 31; figure 3 * * page 38, line 12 - line 22 *; | [A]WO2015200380 (FLEXLITE CORP [US]) [A] 1-10 * abstract * * paragraphs [0055] , [0061] , [0062] *; | [A]US2016175611 (KIM TAE-IL [KR], et al) [A] 1-10* paragraphs [0045] - [0049] - [0066]; figure 4b * | by applicant | - IYER, S. M. et al., "Virally mediated optogenetic excitation and inhibition of pain in freely moving nontransgenic mice", Nat. Biotechnol., (20140000), vol. 32, pages 274 - 8 | - LLEWELLYN, M. E.; THOMPSON, K. R.; DEISSEROTH, K.; DELP, S. L., "Orderly recruitment of motor units under optical control in vivo", Nat. Med., (20100000), vol. 16, pages 1161 - 1165 | - YE, H.; DAOUD-EL BABA, M.; PENG, R.-W.; FUSSENEGGER, M., "A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice", Science, (20110000), vol. 332, doi:doi:10.1126/science.1203535, pages 1565 - 1568, XP002699843 DOI: http://dx.doi.org/10.1126/science.1203535 | - BICKEL, C. S.; GREGORY, C. M.; DEAN, J. C., "Motor unit recruitment during neuromuscular electrical stimulation: A critical appraisal", European Journal of Applied Physiology, (20110000), vol. 111, doi:doi:10.1007/s00421-011-2128-4, pages 2399 - 2407, XP019954347 DOI: http://dx.doi.org/10.1007/s00421-011-2128-4 | - TOWNE, C.; MONTGOMERY, K. L.; IYER, S. M.; DEISSEROTH, K.; DELP, S. L., "Optogenetic control of targeted peripheral axons in freely moving animals", PLoS One, (20130000), vol. 8, page e72691 | - JI, Z.-G. et al., "Light-evoked Somatosensory Perception of Transgenic Rats That Express Channelrhodopsin-2 in Dorsal Root Ganglion Cells", PLoS One, (20120000), vol. 7, page e32699 | - JACQUES, S. L., "Optical properties of biological tissues: a review", Phys. Med. Biol., (20130000), vol. 58, doi:doi:10.1088/0031-9155/58/11/R37, pages R37 - 61, XP020245078 DOI: http://dx.doi.org/10.1088/0031-9155/58/11/R37 | - AYLING, O. G. S.; HARRISON, T. C.; BOYD, J. D.; GOROSHKOV, A.; MURPHY, T. H., "Automated light-based mapping of motor cortex by photoactivation of channelrhodopsin-2 transgenic mice", Nat. Methods, (20090000), vol. 6, doi:doi:10.1038/nmeth.1303, pages 219 - 224, XP055135047 DOI: http://dx.doi.org/10.1038/nmeth.1303 | - CHUONG, A. S. et al., "Noninvasive optical inhibition with a red-shifted microbial rhodopsin", Nat. Neurosci., (20140000), vol. 17, pages 1123 - 9 | - LIN, J. Y.; KNUTSEN, P. M.; MULLER, A.; KLEINFELD, D.; TSIEN, R. Y., "ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation", Nat. Neurosci., (20130000), vol. 16, doi:doi:10.1038/nn.3502, pages 1499 - 508, XP055226552 DOI: http://dx.doi.org/10.1038/nn.3502 | - KIM, T.; FOLCHER, M.; BABA, M. D.-E.; FUSSENEGGER, M. A, "Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Inducible Penile Erection", Angew. Chemie Int. Ed., (20150000), vol. 54, pages 5933 - 5938 | - MAGOWN, P.; SHETTAR, B.; ZHANG, Y.; RAFUSE, V. F., "Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy", Nat. Commun., (20150000), vol. 6, page 8506 | - PETERSON, E. J.; TYLER, D. J., "Motor neuron activation in peripheral nerves using infrared neural stimulation", J. Neural Eng., (20130000), vol. 11, page 016001 | - BASHKATOV, A. N.; GENINA, E. A.; TUCHIN, V. V., "OPTICAL PROPERTIES OF SKIN, SUBCUTANEOUS, AND MUSCLE TISSUES: A REVIEW", J. Innov. Opt. Health Sci., (20110000), vol. 04, pages 9 - 38 | - YAROSLAVSKY, A. N. et al., "Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral range", Phys. Med. Biol., (20020000), vol. 47, page 305 | - ISLAM, M. S. et al., "Extracting structural features of rat sciatic nerve using polarization-sensitive spectral domain optical coherence tomography", J. Biomed. Opt., (20120000), vol. 17, page 056012 | - HENDRIKS, B. H. W. et al., "Nerve detection with optical spectroscopy for regional anesthesia procedures", J. Transl. Med., (20150000), vol. 13, page 380 | - MCCARTNEY, C. J. L.; XU, D.; CONSTANTINESCU, C.; ABBAS, S.; CHAN, V. W. S., "Ultrasound examination of peripheral nerves in the forearm", Reg. Anesth. Pain Med., vol. 32, doi:doi:10.1016/j.rapm.2007.02.011, pages 434 - 9, XP022381897 DOI: http://dx.doi.org/10.1016/j.rapm.2007.02.011 | - HONJOH, T. et al., "Optogenetic Patterning of Whisker-Barrel Cortical System in Transgenic Rat Expressing Channelrhodopsin-2", PLoS One, (20140000), vol. 9, page e93706 | - CHEEVER, T. R.; OLSON, E. A.; ERVASTI, J. M., "Axonal regeneration and neuronal function are preserved in motor neurons lacking ??-actin In Vivo", PLoS One, (20110000), page 6 | - MONTGOMERY, K. L. et al., "Beyond the brain: Optogenetic control in the spinal cord and peripheral nervous system", Sci. Transl. Med., (20160000), vol. 8, page 337rv5 | - BAINBRIDGE, J. W. B. et al., Long-Term Effect of Gene Therapy on Leber's Congenital Amaurosis, (20150000), URL: http://dx.doi.org/10.1056/NEJMoa1414221 | - MINGOZZI, F. et al., "Immune responses to AAV vectors: overcoming barriers to successful gene therapy", Blood, (20130000), vol. 122, doi:doi:10.1182/blood-2013-01-306647, pages 23 - 36, XP055175008 DOI: http://dx.doi.org/10.1182/blood-2013-01-306647 | - SACK, B. K.; HERZOG, R. W., "Evading the immune response upon in vivo gene therapy with viral vectors", Curr. Opin. Mol. Ther., (20090000), vol. 11, pages 493 - 503, XP055128231 | - MASON, M. R. et al., "Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons", Mol. Ther., (20100000), vol. 18, doi:doi:10.1038/mt.2010.19, pages 715 - 724, XP055099555 DOI: http://dx.doi.org/10.1038/mt.2010.19 | - WILLIAMS, E. K. et al., "Sensory Neurons that Detect Stretch and Nutrients in the Digestive System", Cell, (20160000), vol. 166, doi:doi:10.1016/j.cell.2016.05.011, pages 209 - 221, XP029627874 DOI: http://dx.doi.org/10.1016/j.cell.2016.05.011 | - CHANG, R. B.; STROCHLIC, D. E.; WILLIAMS, E. K.; UMANS, B. D.; LIBERLES, S. D., "Vagal Sensory Neuron Subtypes that Differentially Control Breathing", Cell, (20150000), vol. 161, pages 622 - 33 | - GROSENICK, L.; MARSHEL, J. H.; DEISSEROTH, K., "Closed-Loop and Activity-Guided Optogenetic Control", Neuron, (20150000), vol. 86, pages 106 - 139 |