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Extract from the Register of European Patents

EP About this file: EP3464337

EP3464337 - AB6 FAMILY DESIGNER LIGANDS OF TGF-BETA SUPERFAMILY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  02.07.2021
Database last updated on 16.11.2024
FormerGrant of patent is intended
Status updated on  12.10.2020
FormerExamination is in progress
Status updated on  22.06.2020
FormerRequest for examination was made
Status updated on  08.03.2019
FormerThe international publication has been made
Status updated on  08.12.2017
Most recent event   Tooltip02.07.2021Application deemed to be withdrawnpublished on 04.08.2021  [2021/31]
Applicant(s)For all designated states
Mogam Institute for Biomedical Research
93, Ihyeon-ro 30beon-gil
Giheung-gu Yongin-si
Gyeonggi-do 16924 / KR
For all designated states
Joint Center For Biosciences
B-301 Songdo Smart Valley 30
Songdomirae-ro
Yeonsu-gu
Incheon 21990 / KR
[2019/15]
Inventor(s)01 / CHOE, Sen Yon
(Bojeong-dong) 93
Ihyeon-ro 30beon-gil
Giheung-gu
Yongin-si Gyeonggi-do 16924 / KR
02 / AHN, Chi Hoon
(Bojeong-dong) 93
Ihyeon-ro 30beon-gil
Giheung-gu
Yongin-si Gyeonggi-do 16924 / KR
03 / KIM, Ho Cheol
(Bojeong-dong) 93
Ihyeon-ro 30beon-gil
Giheung-gu
Yongin-si Gyeonggi-do 16924 / KR
04 / KIM, Hyeon Jin
(Bojeong-dong) 93
Ihyeon-ro 30beon-gil
Giheung-gu
Yongin-si Gyeonggi-do 16924 / KR
 [2019/15]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[2019/15]
Application number, filing date17807012.431.05.2017
[2019/15]
WO2017KR05703
Priority number, dateUS201662343326P31.05.2016         Original published format: US 201662343326 P
[2019/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017209519
Date:07.12.2017
Language:EN
[2017/49]
Type: A1 Application with search report 
No.:EP3464337
Date:10.04.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 07.12.2017 takes the place of the publication of the European patent application.
[2019/15]
Search report(s)International search report - published on:KR07.12.2017
(Supplementary) European search report - dispatched on:EP15.11.2019
ClassificationIPC:C07K14/495, C07K14/51
[2019/50]
CPC:
C07K14/495 (EP,KR); C07K16/22 (US); C07K14/51 (EP);
C07K16/2863 (US); C07K2317/24 (US); C07K2319/00 (EP,KR)
Former IPC [2019/15]C07K14/495
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/15]
TitleGerman:AB6-FAMILIE-DESIGNERLIGANDEN DER TGF-BETA-SUPERFAMILIE[2019/15]
English:AB6 FAMILY DESIGNER LIGANDS OF TGF-BETA SUPERFAMILY[2019/15]
French:LIGANDS SUR MESURE DE LA FAMILLE AB6 DE LA SUPERFAMILLE TGF-BÊTA[2019/15]
Entry into regional phase28.12.2018National basic fee paid 
28.12.2018Search fee paid 
28.12.2018Designation fee(s) paid 
28.12.2018Examination fee paid 
Examination proceduredeletedDate on which the examining division has become responsible
28.12.2018Examination requested  [2019/15]
20.04.2020Amendment by applicant (claims and/or description)
25.06.2020Despatch of a communication from the examining division (Time limit: M02)
20.08.2020Reply to a communication from the examining division
13.10.2020Communication of intention to grant the patent
24.02.2021Application deemed to be withdrawn, date of legal effect  [2021/31]
17.03.2021Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2021/31]
Fees paidRenewal fee
28.05.2019Renewal fee patent year 03
26.03.2020Renewal fee patent year 04
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]US2015239950  (CHOE SENYON [US], et al) [Y] 1-3,7-9 * claims 1-20 * * table B * * paragraphs [0005] , [0 60] - [0069] - [0 81] , [ 148] , [ 151] , [ 174] - [0180] - [ 249] *;
 [Y]  - BYUNG-HAK YOON ET AL, "An Activin A/BMP2 Chimera, AB204, Displays Bone-Healing Properties Superior to Those of BMP2 : BONE-HEALING PROPERTIES OF AN ACTIVIN A/BMP2 CHIMERA", JOURNAL OF BONE AND MINERAL RESEARCH, US, (20140820), vol. 29, no. 9, doi:10.1002/jbmr.2238, ISSN 0884-0431, pages 1950 - 1959, XP055630032 [Y] 1-3,7-9 * the whole document *

DOI:   http://dx.doi.org/10.1002/jbmr.2238
 [Y]  - WITEK KWIATKOWSKI ET AL, "Engineering TGF-[beta] superfamily ligands for clinical applications", TRENDS IN PHARMACOLOGICAL SCIENCES., GB, (20141201), vol. 35, no. 12, doi:10.1016/j.tips.2014.10.006, ISSN 0165-6147, pages 648 - 657, XP055630589 [Y] 1-3,7-9 * the whole document *

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 [Y]  - GEORGE P. ALLENDORPH ET AL, "Designer TGF[beta] Superfamily Ligands with Diversified Functionality", PLOS ONE, (20111104), vol. 6, no. 11, doi:10.1371/journal.pone.0026402, page e26402, XP055630590 [Y] 1-3,7-9 * the whole document *

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 [A]  - GEORGE P. ALLENDORPH ET AL, "BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors + , +", BIOCHEMISTRY, (20071001), vol. 46, no. 43, doi:10.1021/bi700907k, ISSN 0006-2960, pages 12238 - 12247, XP055071961 [A] 1-9 * page 6, column L, paragraph 4; figure 4a *

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DOI:   http://dx.doi.org/10.1074/jbc.M704530200
 [T]  - AHN C ET AL, "AB604, an activin a/bone morphogenetic protein 6 (BMP6) chimera, has potential anti-fibrotic properties", EMBASE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (20171001), Database accession no. EMB-618937010, XP002794839 [T] 1-9 * the whole document *
 [P]  - AHN C ET AL, "AB604, an activin a/bone morphogenetic protein 6 (BMP6) chimera, has potential anti-fibrotic properties", HEPATOLOGY 20171001 JOHN WILEY AND SONS INC. NLD, (20171001), vol. 66, no. Supplement 1, ISSN 1527-3350, pages 223A CONF 20171020 to 20171024 Washington, DC - 68th Annu
International search[A]US5756308  (WOLFMAN NEIL M [US], et al) [A] 1-9* See the whole document. *;
 [A]US2005250936  (OPPERMANN HERMANN [US], et al) [A] 1-9 * See the whole document. *;
 [X]US2015239950  (CHOE SENYON [US], et al) [X] 1-9 * See abstract; paragraphs [0005], [0060]-[0069], [0081], [0148], [0151], [0174] [0180], [0249]; Table B; claim 1. *;
 [A]  - KORUPOLU et al., "Activin A/bone morphogenetic protein (BMP) chimeras exhibit BMP-like activity and antagonize activin and myostatin", The Journal of Biological Chemistry, (20080000), vol. 283, no. 7, pages 3782 - 3790, XP008150979 [A] 1-9 * See the whole document. *

DOI:   http://dx.doi.org/10.1074/jbc.M704530200
 [A]  - JIMENEZ et al., "Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes", Scientific Reports, (20150000), vol. 5, pages 1 - 8, XP055446084 [A] 1-9 * See the whole document. *

DOI:   http://dx.doi.org/10.1038/srep16400
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    - BYUNG-HAK YOON et al., "An Activin A/BMP2 Chimera, AB204, Displays Bone-Healing Properties Superior to Those of BMP2 : BONE-HEALING PROPERTIES OF AN ACTIVIN A/BMP2 CHIMERA", JOURNAL OF BONE AND MINERAL RESEARCH, (20140820), vol. 29, no. 9, doi:10.1002/jbmr.2238, ISSN 0884-0431, pages 1950 - 1959, XP055630032

DOI:   http://dx.doi.org/10.1002/jbmr.2238
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